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Items: 1 to 50 of 366

1.

Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients.

Castellazzi M, Patergnani S, Donadio M, Giorgi C, Bonora M, Fainardi E, Casetta I, Granieri E, Pugliatti M, Pinton P.

J Neuroinflammation. 2019 Jun 27;16(1):131. doi: 10.1186/s12974-019-1526-0.

2.

Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective.

Rimessi A, Pedriali G, Vezzani B, Tarocco A, Marchi S, Wieckowski MR, Giorgi C, Pinton P.

Semin Cell Dev Biol. 2019 May 24. pii: S1084-9521(18)30182-4. doi: 10.1016/j.semcdb.2019.05.015. [Epub ahead of print] Review.

PMID:
31108186
3.

A New Current for the Mitochondrial Permeability Transition.

Bonora M, Pinton P.

Trends Biochem Sci. 2019 Jul;44(7):559-561. doi: 10.1016/j.tibs.2019.04.009. Epub 2019 May 7.

PMID:
31076251
4.

Mitochondrial calcium uniporter complex modulation in cancerogenesis.

Marchi S, Vitto VAM, Danese A, Wieckowski MR, Giorgi C, Pinton P.

Cell Cycle. 2019 May;18(10):1068-1083. doi: 10.1080/15384101.2019.1612698. Epub 2019 May 10.

PMID:
31032692
5.

Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care.

Tarocco A, Caroccia N, Morciano G, Wieckowski MR, Ancora G, Garani G, Pinton P.

Cell Death Dis. 2019 Apr 8;10(4):317. doi: 10.1038/s41419-019-1556-7. Review.

6.

High mitochondrial Ca2+ content increases cancer cell proliferation upon inhibition of mitochondrial permeability transition pore (mPTP).

Marchi S, Vitto VAM, Patergnani S, Pinton P.

Cell Cycle. 2019 Apr;18(8):914-916. doi: 10.1080/15384101.2019.1598729. Epub 2019 Apr 7. No abstract available.

PMID:
30909805
7.

Effects of Mycotoxins on the Intestine.

Alassane-Kpembi I, Pinton P, Oswald IP.

Toxins (Basel). 2019 Mar 13;11(3). pii: E159. doi: 10.3390/toxins11030159.

8.

Deoxynivalenol inhibits the expression of trefoil factors (TFF) by intestinal human and porcine goblet cells.

Graziani F, Pinton P, Olleik H, Pujol A, Nicoletti C, Sicre M, Quinson N, Ajandouz EH, Perrier J, Pasquale ED, Oswald IP, Maresca M.

Arch Toxicol. 2019 Apr;93(4):1039-1049. doi: 10.1007/s00204-019-02425-6. Epub 2019 Mar 11.

PMID:
30854615
9.

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.

D'Eletto M, Rossin F, Occhigrossi L, Farrace MG, Faccenda D, Desai R, Marchi S, Refolo G, Falasca L, Antonioli M, Ciccosanti F, Fimia GM, Pinton P, Campanella M, Piacentini M.

Cell Rep. 2018 Dec 26;25(13):3573-3581.e4. doi: 10.1016/j.celrep.2018.11.094.

10.

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth.

Marchi S, Corricelli M, Branchini A, Vitto VAM, Missiroli S, Morciano G, Perrone M, Ferrarese M, Giorgi C, Pinotti M, Galluzzi L, Kroemer G, Pinton P.

EMBO J. 2019 Jan 15;38(2). pii: e99435. doi: 10.15252/embj.201899435. Epub 2018 Nov 30.

PMID:
30504268
11.

Membrane-potential compensation reveals mitochondrial volume expansion during HSC commitment.

Bonora M, Ito K, Morganti C, Pinton P, Ito K.

Exp Hematol. 2018 Dec;68:30-37.e1. doi: 10.1016/j.exphem.2018.10.012. Epub 2018 Nov 3.

12.

A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss.

Pozzer D, Varone E, Chernorudskiy A, Schiarea S, Missiroli S, Giorgi C, Pinton P, Canato M, Germinario E, Nogara L, Blaauw B, Zito E.

Redox Biol. 2019 Jan;20:354-366. doi: 10.1016/j.redox.2018.10.017. Epub 2018 Oct 26.

13.

NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus.

Kuchay S, Saeed M, Giorgi C, Li J, Hoffmann HH, Pinton P, Rice CM, Pagano M.

Cell Rep. 2018 Oct 23;25(4):833-840.e3. doi: 10.1016/j.celrep.2018.09.088.

14.

ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome.

Angebault C, Fauconnier J, Patergnani S, Rieusset J, Danese A, Affortit CA, Jagodzinska J, Mégy C, Quiles M, Cazevieille C, Korchagina J, Bonnet-Wersinger D, Milea D, Hamel C, Pinton P, Thiry M, Lacampagne A, Delprat B, Delettre C.

Sci Signal. 2018 Oct 23;11(553). pii: eaaq1380. doi: 10.1126/scisignal.aaq1380.

PMID:
30352948
15.

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G.

Cell Death Differ. 2018 Nov;25(11):1885-1904. doi: 10.1038/s41418-018-0213-5. Epub 2018 Oct 15.

PMID:
30323273
16.

Overview and Comparison of Intestinal Organotypic Models, Intestinal Cells, and Intestinal Explants Used for Toxicity Studies.

Maresca M, Pinton P, Ajandouz EH, Menard S, Ferrier L, Oswald IP.

Curr Top Microbiol Immunol. 2018 Sep 28. doi: 10.1007/82_2018_142. [Epub ahead of print]

PMID:
30259111
17.

IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice.

Valladares D, Utreras-Mendoza Y, Campos C, Morales C, Diaz-Vegas A, Contreras-Ferrat A, Westermeier F, Jaimovich E, Marchi S, Pinton P, Lavandero S.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3685-3695. doi: 10.1016/j.bbadis.2018.08.042. Epub 2018 Sep 7.

PMID:
30251688
18.

Publisher Correction: The machineries, regulation and cellular functions of mitochondrial calcium.

Giorgi C, Marchi S, Pinton P.

Nat Rev Mol Cell Biol. 2018 Nov;19(11):746. doi: 10.1038/s41580-018-0066-2.

PMID:
30250295
19.

Mitochondrial DNA keeps you young.

Bonora M, Pinton P.

Cell Death Dis. 2018 Sep 24;9(10):992. doi: 10.1038/s41419-018-1045-4. No abstract available.

20.

Review article: Role of satiety hormones in anorexia induction by Trichothecene mycotoxins.

Terciolo C, Maresca M, Pinton P, Oswald IP.

Food Chem Toxicol. 2018 Nov;121:701-714. doi: 10.1016/j.fct.2018.09.034. Epub 2018 Sep 20. Review.

PMID:
30243968
21.

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles.

Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L.

Nat Rev Cardiol. 2019 Jan;16(1):33-55. doi: 10.1038/s41569-018-0074-0. Review.

PMID:
30177752
22.

Deepoxy-deoxynivalenol retains some immune-modulatory properties of the parent molecule deoxynivalenol in piglets.

Pierron A, Bracarense APFL, Cossalter AM, Laffitte J, Schwartz-Zimmermann HE, Schatzmayr G, Pinton P, Moll WD, Oswald IP.

Arch Toxicol. 2018 Nov;92(11):3381-3389. doi: 10.1007/s00204-018-2293-x. Epub 2018 Aug 31.

PMID:
30171291
23.

The machineries, regulation and cellular functions of mitochondrial calcium.

Giorgi C, Marchi S, Pinton P.

Nat Rev Mol Cell Biol. 2018 Nov;19(11):713-730. doi: 10.1038/s41580-018-0052-8. Review. Erratum in: Nat Rev Mol Cell Biol. 2018 Sep 24;:.

PMID:
30143745
24.

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, Patalas-Krawczyk P, Borchard S, Jędrak P, Pierzynowska K, Szymański J, Wang DQ, Portincasa P, Węgrzyn G, Zischka H, Dobrzyn P, Bonora M, Duszynski J, Rimessi A, Karkucinska-Wieckowska A, Dobrzyn A, Szabadkai G, Zavan B, Oliveira PJ, Sardao VA, Pinton P, Wieckowski MR.

Int Rev Cell Mol Biol. 2018;340:209-344. doi: 10.1016/bs.ircmb.2018.05.006. Epub 2018 Jun 22. Review.

PMID:
30072092
25.

Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction.

Morciano G, Preti D, Pedriali G, Aquila G, Missiroli S, Fantinati A, Caroccia N, Pacifico S, Bonora M, Talarico A, Morganti C, Rizzo P, Ferrari R, Wieckowski MR, Campo G, Giorgi C, Trapella C, Pinton P.

J Med Chem. 2018 Aug 23;61(16):7131-7143. doi: 10.1021/acs.jmedchem.8b00278. Epub 2018 Aug 9.

PMID:
30060655
26.

STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses.

Avalle L, Camporeale A, Morciano G, Caroccia N, Ghetti E, Orecchia V, Viavattene D, Giorgi C, Pinton P, Poli V.

Cell Death Differ. 2019 May;26(5):932-942. doi: 10.1038/s41418-018-0171-y. Epub 2018 Jul 24.

27.

LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.

Gibellini L, Losi L, De Biasi S, Nasi M, Lo Tartaro D, Pecorini S, Patergnani S, Pinton P, De Gaetano A, Carnevale G, Pisciotta A, Mariani F, Roncucci L, Iannone A, Cossarizza A, Pinti M.

Front Oncol. 2018 Jul 9;8:254. doi: 10.3389/fonc.2018.00254. eCollection 2018.

28.

The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation.

Pignani S, Todaro A, Ferrarese M, Marchi S, Lombardi S, Balestra D, Pinton P, Bernardi F, Pinotti M, Branchini A.

J Thromb Haemost. 2018 Oct;16(10):2035-2043. doi: 10.1111/jth.14236. Epub 2018 Aug 9.

PMID:
29993188
29.

Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2.

Bittremieux M, La Rovere RM, Akl H, Martines C, Welkenhuyzen K, Dubron K, Baes M, Janssens A, Vandenberghe P, Laurenti L, Rietdorf K, Morciano G, Pinton P, Mikoshiba K, Bootman MD, Efremov DG, De Smedt H, Parys JB, Bultynck G.

Cell Death Differ. 2019 Mar;26(3):531-547. doi: 10.1038/s41418-018-0142-3. Epub 2018 Jun 13.

30.

Fumonisin-Exposure Impairs Age-Related Ecological Succession of Bacterial Species in Weaned Pig Gut Microbiota.

Mateos I, Combes S, Pascal G, Cauquil L, Barilly C, Cossalter AM, Laffitte J, Botti S, Pinton P, Oswald IP.

Toxins (Basel). 2018 Jun 5;10(6). pii: E230. doi: 10.3390/toxins10060230.

31.

Relation Between Mitochondrial Membrane Potential and ROS Formation.

Suski J, Lebiedzinska M, Bonora M, Pinton P, Duszynski J, Wieckowski MR.

Methods Mol Biol. 2018;1782:357-381. doi: 10.1007/978-1-4939-7831-1_22.

PMID:
29851012
32.

Heart rate reduction with ivabradine in the early phase of atherosclerosis is protective in the endothelium of ApoE-deficient mice.

Aquila G, Morelli MB, Vieceli Dalla Sega F, Fortini F, Nigro P, Caliceti C, Ferracin M, Negrini M, Pannuti A, Bonora M, Pinton P, Ferrari R, Rizzo P.

J Physiol Pharmacol. 2018 Feb;69(1):35-52. doi: 10.26402/jpp.2018.1.04. Epub 2018 May 8.

33.

Saccharomyces cerevisiae Boulardii Reduces the Deoxynivalenol-Induced Alteration of the Intestinal Transcriptome.

Alassane-Kpembi I, Pinton P, Hupé JF, Neves M, Lippi Y, Combes S, Castex M, Oswald IP.

Toxins (Basel). 2018 May 15;10(5). pii: E199. doi: 10.3390/toxins10050199.

34.

Ergot Alkaloids at Doses Close to EU Regulatory Limits Induce Alterations of the Liver and Intestine.

Maruo VM, Bracarense AP, Metayer JP, Vilarino M, Oswald IP, Pinton P.

Toxins (Basel). 2018 May 1;10(5). pii: E183. doi: 10.3390/toxins10050183.

35.

PLCB3 Loss of Function Reduces Pseudomonas aeruginosa-Dependent IL-8 Release in Cystic Fibrosis.

Rimessi A, Bezzerri V, Salvatori F, Tamanini A, Nigro F, Dechecchi MC, Santangelo A, Prandini P, Munari S, Provezza L, Garreau de Loubresse N, Muller J, Ribeiro CMP, Lippi G, Gambari R, Pinton P, Cabrini G.

Am J Respir Cell Mol Biol. 2018 Oct;59(4):428-436. doi: 10.1165/rcmb.2017-0267OC.

PMID:
29668297
36.

Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.

Morciano G, Marchi S, Morganti C, Sbano L, Bittremieux M, Kerkhofs M, Corricelli M, Danese A, Karkucinska-Wieckowska A, Wieckowski MR, Bultynck G, Giorgi C, Pinton P.

Neoplasia. 2018 May;20(5):510-523. doi: 10.1016/j.neo.2018.03.005. Epub 2018 Apr 5. Review.

37.

Mitochondria-associated membranes (MAMs) and pathologies.

Pinton P.

Cell Death Dis. 2018 Apr 1;9(4):413. doi: 10.1038/s41419-018-0424-1. No abstract available.

38.

Vav1 is necessary for PU.1 mediated upmodulation of miR-29b in acute myeloid leukaemia-derived cells.

Vezzali F, Grassilli S, Lambertini E, Brugnoli F, Patergnani S, Nika E, Piva R, Pinton P, Capitani S, Bertagnolo V.

J Cell Mol Med. 2018 Jun;22(6):3149-3158. doi: 10.1111/jcmm.13594. Epub 2018 Mar 13.

39.

Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes.

Kerkhofs M, Bittremieux M, Morciano G, Giorgi C, Pinton P, Parys JB, Bultynck G.

Cell Death Dis. 2018 Feb 28;9(3):334. doi: 10.1038/s41419-017-0179-0. Review.

40.

Editorial: Inter-Organelle Calcium Communication in Cancer.

Cardenas C, Pinton P, Bultynck G.

Front Oncol. 2018 Feb 6;8:14. doi: 10.3389/fonc.2018.00014. eCollection 2018. No abstract available.

41.

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease.

Tozzi A, Tantucci M, Marchi S, Mazzocchetti P, Morari M, Pinton P, Mancini A, Calabresi P.

Cell Death Dis. 2018 Feb 12;9(2):204. doi: 10.1038/s41419-017-0221-2.

42.

Gelatin-genipin-based biomaterials for skeletal muscle tissue engineering.

Gattazzo F, De Maria C, Rimessi A, Donà S, Braghetta P, Pinton P, Vozzi G, Bonaldo P.

J Biomed Mater Res B Appl Biomater. 2018 Nov;106(8):2763-2777. doi: 10.1002/jbm.b.34057. Epub 2018 Feb 7.

PMID:
29412500
43.

Calcium Dynamics as a Machine for Decoding Signals.

Giorgi C, Danese A, Missiroli S, Patergnani S, Pinton P.

Trends Cell Biol. 2018 Apr;28(4):258-273. doi: 10.1016/j.tcb.2018.01.002. Epub 2018 Feb 3. Review.

PMID:
29409699
44.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

45.

MicroRNA501-5p induces p53 proteasome degradation through the activation of the mTOR/MDM2 pathway in ADPKD cells.

de Stephanis L, Mangolini A, Servello M, Harris PC, Dell'Atti L, Pinton P, Aguiari G.

J Cell Physiol. 2018 Sep;233(9):6911-6924. doi: 10.1002/jcp.26473. Epub 2018 Mar 25.

PMID:
29323708
46.

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

Civiero L, Cogo S, Kiekens A, Morganti C, Tessari I, Lobbestael E, Baekelandt V, Taymans JM, Chartier-Harlin MC, Franchin C, Arrigoni G, Lewis PA, Piccoli G, Bubacco L, Cookson MR, Pinton P, Greggio E.

Front Mol Neurosci. 2017 Dec 14;10:417. doi: 10.3389/fnmol.2017.00417. eCollection 2017.

47.

Mitochondria in non-alcoholic fatty liver disease.

Simões ICM, Fontes A, Pinton P, Zischka H, Wieckowski MR.

Int J Biochem Cell Biol. 2018 Feb;95:93-99. doi: 10.1016/j.biocel.2017.12.019. Epub 2017 Dec 26. Review.

48.

Analysis of the interactions between environmental and food contaminants, cadmium and deoxynivalenol, in different target organs.

Le TH, Alassane-Kpembi I, Oswald IP, Pinton P.

Sci Total Environ. 2018 May 1;622-623:841-848. doi: 10.1016/j.scitotenv.2017.12.014. Epub 2017 Dec 13.

PMID:
29223910
49.

Porcine Small and Large Intestinal Microbiota Rapidly Hydrolyze the Masked Mycotoxin Deoxynivalenol-3-Glucoside and Release Deoxynivalenol in Spiked Batch Cultures In Vitro.

Gratz SW, Currie V, Richardson AJ, Duncan G, Holtrop G, Farquharson F, Louis P, Pinton P, Oswald IP.

Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e02106-17. doi: 10.1128/AEM.02106-17. Print 2018 Jan 15.

50.

Intestinal toxicity of deoxynivalenol is limited by Lactobacillus rhamnosus RC007 in pig jejunum explants.

García GR, Payros D, Pinton P, Dogi CA, Laffitte J, Neves M, González Pereyra ML, Cavaglieri LR, Oswald IP.

Arch Toxicol. 2018 Feb;92(2):983-993. doi: 10.1007/s00204-017-2083-x. Epub 2017 Oct 9.

PMID:
28993953

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