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Items: 1 to 50 of 379

1.

Fluorescent Light Energy (FLE) Acts on Mitochondrial Physiology Improving Wound Healing.

Ferroni L, Zago M, Patergnani S, Campbell SE, Hébert L, Nielsen M, Scarpa C, Bassetto F, Pinton P, Zavan B.

J Clin Med. 2020 Feb 18;9(2). pii: E559. doi: 10.3390/jcm9020559.

2.

Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer's disease and mild cognitive impairment.

Castellazzi M, Patergnani S, Donadio M, Giorgi C, Bonora M, Bosi C, Brombo G, Pugliatti M, Seripa D, Zuliani G, Pinton P.

Sci Rep. 2019 Dec 27;9(1):20009. doi: 10.1038/s41598-019-56614-5.

3.

Co-occurrence of DON and Emerging Mycotoxins in Worldwide Finished Pig Feed and Their Combined Toxicity in Intestinal Cells.

Khoshal AK, Novak B, Martin PGP, Jenkins T, Neves M, Schatzmayr G, Oswald IP, Pinton P.

Toxins (Basel). 2019 Dec 11;11(12). pii: E727. doi: 10.3390/toxins11120727.

4.

Systematic Review with Network Meta-Analysis: Comparative Efficacy and Safety of Combination Therapy with Angiotensin II Receptor Blockers and Amlodipine in Asian Hypertensive Patients.

Lee DW, Jung M, Wang HW, Khan Z, Pinton P.

Int J Hypertens. 2019 Nov 11;2019:9516279. doi: 10.1155/2019/9516279. eCollection 2019.

5.

Translational readthrough of GLA nonsense mutations suggests dominant-negative effects exerted by the interaction of wild-type and missense variants.

Lombardi S, Ferrarese M, Marchi S, Pinton P, Pinotti M, Bernardi F, Branchini A.

RNA Biol. 2020 Feb;17(2):254-263. doi: 10.1080/15476286.2019.1676115. Epub 2019 Oct 15.

PMID:
31613176
6.

KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction.

Vieceli Dalla Sega F, Mastrocola R, Aquila G, Fortini F, Fornelli C, Zotta A, Cento AS, Perrelli A, Boda E, Pannuti A, Marchi S, Pinton P, Ferrari R, Rizzo P, Retta SF.

Int J Mol Sci. 2019 Oct 5;20(19). pii: E4930. doi: 10.3390/ijms20194930.

7.

Fumonisins at Doses below EU Regulatory Limits Induce Histological Alterations in Piglets.

Terciolo C, Bracarense AP, Souto PCMC, Cossalter AM, Dopavogui L, Loiseau N, Oliveira CAF, Pinton P, Oswald IP.

Toxins (Basel). 2019 Sep 19;11(9). pii: E548. doi: 10.3390/toxins11090548.

8.

Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane.

Bestetti S, Galli M, Sorrentino I, Pinton P, Rimessi A, Sitia R, Medraño-Fernandez I.

Redox Biol. 2020 Jan;28:101326. doi: 10.1016/j.redox.2019.101326. Epub 2019 Sep 12.

9.

Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo.

Petralla S, Peña-Altamira LE, Poeta E, Massenzio F, Virgili M, Barile SN, Sbano L, Profilo E, Corricelli M, Danese A, Giorgi C, Ostan R, Capri M, Pinton P, Palmieri F, Lasorsa FM, Monti B.

Int J Mol Sci. 2019 Sep 11;20(18). pii: E4486. doi: 10.3390/ijms20184486.

10.

Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma.

Shankaraiah RC, Callegari E, Guerriero P, Rimessi A, Pinton P, Gramantieri L, Silini EM, Sabbioni S, Negrini M.

Oncogene. 2019 Nov;38(45):7035-7045. doi: 10.1038/s41388-019-0942-z. Epub 2019 Aug 13.

PMID:
31409896
11.

In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier.

Luo S, Terciolo C, Bracarense APFL, Payros D, Pinton P, Oswald IP.

Environ Int. 2019 Nov;132:105082. doi: 10.1016/j.envint.2019.105082. Epub 2019 Aug 7.

12.

Mitochondrial functionality and metabolism in T cells from progressive multiple sclerosis patients.

De Biasi S, Simone AM, Bianchini E, Lo Tartaro D, Pecorini S, Nasi M, Patergnani S, Carnevale G, Gibellini L, Ferraro D, Vitetta F, Pinton P, Sola P, Cossarizza A, Pinti M.

Eur J Immunol. 2019 Dec;49(12):2204-2221. doi: 10.1002/eji.201948223. Epub 2019 Aug 16.

PMID:
31373677
13.

Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells.

Mollo N, Nitti M, Zerillo L, Faicchia D, Micillo T, Accarino R, Secondo A, Petrozziello T, Calì G, Cicatiello R, Bonfiglio F, Sarnataro V, Genesio R, Izzo A, Pinton P, Matarese G, Paladino S, Conti A, Nitsch L.

Front Genet. 2019 Jun 28;10:606. doi: 10.3389/fgene.2019.00606. eCollection 2019.

14.

Characterization of Dermal Stem Cells of Diabetic Patients.

Ferroni L, Gardin C, Dalla Paola L, Campo G, Cimaglia P, Bellin G, Pinton P, Zavan B.

Cells. 2019 Jul 16;8(7). pii: E729. doi: 10.3390/cells8070729.

15.

Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients.

Castellazzi M, Patergnani S, Donadio M, Giorgi C, Bonora M, Fainardi E, Casetta I, Granieri E, Pugliatti M, Pinton P.

J Neuroinflammation. 2019 Jun 27;16(1):131. doi: 10.1186/s12974-019-1526-0.

16.

Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective.

Rimessi A, Pedriali G, Vezzani B, Tarocco A, Marchi S, Wieckowski MR, Giorgi C, Pinton P.

Semin Cell Dev Biol. 2020 Feb;98:167-180. doi: 10.1016/j.semcdb.2019.05.015. Epub 2019 May 24. Review.

PMID:
31108186
17.

A New Current for the Mitochondrial Permeability Transition.

Bonora M, Pinton P.

Trends Biochem Sci. 2019 Jul;44(7):559-561. doi: 10.1016/j.tibs.2019.04.009. Epub 2019 May 7.

PMID:
31076251
18.

Mitochondrial calcium uniporter complex modulation in cancerogenesis.

Marchi S, Vitto VAM, Danese A, Wieckowski MR, Giorgi C, Pinton P.

Cell Cycle. 2019 May;18(10):1068-1083. doi: 10.1080/15384101.2019.1612698. Epub 2019 May 10.

PMID:
31032692
19.

Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care.

Tarocco A, Caroccia N, Morciano G, Wieckowski MR, Ancora G, Garani G, Pinton P.

Cell Death Dis. 2019 Apr 8;10(4):317. doi: 10.1038/s41419-019-1556-7. Review.

20.

High mitochondrial Ca2+ content increases cancer cell proliferation upon inhibition of mitochondrial permeability transition pore (mPTP).

Marchi S, Vitto VAM, Patergnani S, Pinton P.

Cell Cycle. 2019 Apr;18(8):914-916. doi: 10.1080/15384101.2019.1598729. Epub 2019 Apr 7. No abstract available.

PMID:
30909805
21.

Effects of Mycotoxins on the Intestine.

Alassane-Kpembi I, Pinton P, Oswald IP.

Toxins (Basel). 2019 Mar 13;11(3). pii: E159. doi: 10.3390/toxins11030159.

22.

Deoxynivalenol inhibits the expression of trefoil factors (TFF) by intestinal human and porcine goblet cells.

Graziani F, Pinton P, Olleik H, Pujol A, Nicoletti C, Sicre M, Quinson N, Ajandouz EH, Perrier J, Pasquale ED, Oswald IP, Maresca M.

Arch Toxicol. 2019 Apr;93(4):1039-1049. doi: 10.1007/s00204-019-02425-6. Epub 2019 Mar 11.

PMID:
30854615
23.

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.

D'Eletto M, Rossin F, Occhigrossi L, Farrace MG, Faccenda D, Desai R, Marchi S, Refolo G, Falasca L, Antonioli M, Ciccosanti F, Fimia GM, Pinton P, Campanella M, Piacentini M.

Cell Rep. 2018 Dec 26;25(13):3573-3581.e4. doi: 10.1016/j.celrep.2018.11.094.

24.

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth.

Marchi S, Corricelli M, Branchini A, Vitto VAM, Missiroli S, Morciano G, Perrone M, Ferrarese M, Giorgi C, Pinotti M, Galluzzi L, Kroemer G, Pinton P.

EMBO J. 2019 Jan 15;38(2). pii: e99435. doi: 10.15252/embj.201899435. Epub 2018 Nov 30.

25.

Membrane-potential compensation reveals mitochondrial volume expansion during HSC commitment.

Bonora M, Ito K, Morganti C, Pinton P, Ito K.

Exp Hematol. 2018 Dec;68:30-37.e1. doi: 10.1016/j.exphem.2018.10.012. Epub 2018 Nov 3.

26.

A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss.

Pozzer D, Varone E, Chernorudskiy A, Schiarea S, Missiroli S, Giorgi C, Pinton P, Canato M, Germinario E, Nogara L, Blaauw B, Zito E.

Redox Biol. 2019 Jan;20:354-366. doi: 10.1016/j.redox.2018.10.017. Epub 2018 Oct 26.

27.

NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus.

Kuchay S, Saeed M, Giorgi C, Li J, Hoffmann HH, Pinton P, Rice CM, Pagano M.

Cell Rep. 2018 Oct 23;25(4):833-840.e3. doi: 10.1016/j.celrep.2018.09.088.

28.

ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome.

Angebault C, Fauconnier J, Patergnani S, Rieusset J, Danese A, Affortit CA, Jagodzinska J, Mégy C, Quiles M, Cazevieille C, Korchagina J, Bonnet-Wersinger D, Milea D, Hamel C, Pinton P, Thiry M, Lacampagne A, Delprat B, Delettre C.

Sci Signal. 2018 Oct 23;11(553). pii: eaaq1380. doi: 10.1126/scisignal.aaq1380.

29.

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G.

Cell Death Differ. 2018 Nov;25(11):1885-1904. doi: 10.1038/s41418-018-0213-5. Epub 2018 Oct 15. Review.

30.

Overview and Comparison of Intestinal Organotypic Models, Intestinal Cells, and Intestinal Explants Used for Toxicity Studies.

Maresca M, Pinton P, Ajandouz EH, Menard S, Ferrier L, Oswald IP.

Curr Top Microbiol Immunol. 2018 Sep 28. doi: 10.1007/82_2018_142. [Epub ahead of print]

PMID:
30259111
31.

IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice.

Valladares D, Utreras-Mendoza Y, Campos C, Morales C, Diaz-Vegas A, Contreras-Ferrat A, Westermeier F, Jaimovich E, Marchi S, Pinton P, Lavandero S.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3685-3695. doi: 10.1016/j.bbadis.2018.08.042. Epub 2018 Sep 7.

32.

Publisher Correction: The machineries, regulation and cellular functions of mitochondrial calcium.

Giorgi C, Marchi S, Pinton P.

Nat Rev Mol Cell Biol. 2018 Nov;19(11):746. doi: 10.1038/s41580-018-0066-2.

PMID:
30250295
33.

Mitochondrial DNA keeps you young.

Bonora M, Pinton P.

Cell Death Dis. 2018 Sep 24;9(10):992. doi: 10.1038/s41419-018-1045-4. No abstract available.

34.

Review article: Role of satiety hormones in anorexia induction by Trichothecene mycotoxins.

Terciolo C, Maresca M, Pinton P, Oswald IP.

Food Chem Toxicol. 2018 Nov;121:701-714. doi: 10.1016/j.fct.2018.09.034. Epub 2018 Sep 20. Review.

PMID:
30243968
35.

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles.

Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L.

Nat Rev Cardiol. 2019 Jan;16(1):33-55. doi: 10.1038/s41569-018-0074-0. Review.

36.

Deepoxy-deoxynivalenol retains some immune-modulatory properties of the parent molecule deoxynivalenol in piglets.

Pierron A, Bracarense APFL, Cossalter AM, Laffitte J, Schwartz-Zimmermann HE, Schatzmayr G, Pinton P, Moll WD, Oswald IP.

Arch Toxicol. 2018 Nov;92(11):3381-3389. doi: 10.1007/s00204-018-2293-x. Epub 2018 Aug 31.

PMID:
30171291
37.

The machineries, regulation and cellular functions of mitochondrial calcium.

Giorgi C, Marchi S, Pinton P.

Nat Rev Mol Cell Biol. 2018 Nov;19(11):713-730. doi: 10.1038/s41580-018-0052-8. Review. Erratum in: Nat Rev Mol Cell Biol. 2018 Sep 24;:.

PMID:
30143745
38.

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, Patalas-Krawczyk P, Borchard S, Jędrak P, Pierzynowska K, Szymański J, Wang DQ, Portincasa P, Węgrzyn G, Zischka H, Dobrzyn P, Bonora M, Duszynski J, Rimessi A, Karkucinska-Wieckowska A, Dobrzyn A, Szabadkai G, Zavan B, Oliveira PJ, Sardao VA, Pinton P, Wieckowski MR.

Int Rev Cell Mol Biol. 2018;340:209-344. doi: 10.1016/bs.ircmb.2018.05.006. Epub 2018 Jun 22. Review.

PMID:
30072092
39.

Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction.

Morciano G, Preti D, Pedriali G, Aquila G, Missiroli S, Fantinati A, Caroccia N, Pacifico S, Bonora M, Talarico A, Morganti C, Rizzo P, Ferrari R, Wieckowski MR, Campo G, Giorgi C, Trapella C, Pinton P.

J Med Chem. 2018 Aug 23;61(16):7131-7143. doi: 10.1021/acs.jmedchem.8b00278. Epub 2018 Aug 9.

PMID:
30060655
40.

STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses.

Avalle L, Camporeale A, Morciano G, Caroccia N, Ghetti E, Orecchia V, Viavattene D, Giorgi C, Pinton P, Poli V.

Cell Death Differ. 2019 May;26(5):932-942. doi: 10.1038/s41418-018-0171-y. Epub 2018 Jul 24.

41.

LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells.

Gibellini L, Losi L, De Biasi S, Nasi M, Lo Tartaro D, Pecorini S, Patergnani S, Pinton P, De Gaetano A, Carnevale G, Pisciotta A, Mariani F, Roncucci L, Iannone A, Cossarizza A, Pinti M.

Front Oncol. 2018 Jul 9;8:254. doi: 10.3389/fonc.2018.00254. eCollection 2018.

42.

The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation.

Pignani S, Todaro A, Ferrarese M, Marchi S, Lombardi S, Balestra D, Pinton P, Bernardi F, Pinotti M, Branchini A.

J Thromb Haemost. 2018 Oct;16(10):2035-2043. doi: 10.1111/jth.14236. Epub 2018 Aug 9.

PMID:
29993188
43.

Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2.

Bittremieux M, La Rovere RM, Akl H, Martines C, Welkenhuyzen K, Dubron K, Baes M, Janssens A, Vandenberghe P, Laurenti L, Rietdorf K, Morciano G, Pinton P, Mikoshiba K, Bootman MD, Efremov DG, De Smedt H, Parys JB, Bultynck G.

Cell Death Differ. 2019 Mar;26(3):531-547. doi: 10.1038/s41418-018-0142-3. Epub 2018 Jun 13.

44.

Fumonisin-Exposure Impairs Age-Related Ecological Succession of Bacterial Species in Weaned Pig Gut Microbiota.

Mateos I, Combes S, Pascal G, Cauquil L, Barilly C, Cossalter AM, Laffitte J, Botti S, Pinton P, Oswald IP.

Toxins (Basel). 2018 Jun 5;10(6). pii: E230. doi: 10.3390/toxins10060230.

45.

Relation Between Mitochondrial Membrane Potential and ROS Formation.

Suski J, Lebiedzinska M, Bonora M, Pinton P, Duszynski J, Wieckowski MR.

Methods Mol Biol. 2018;1782:357-381. doi: 10.1007/978-1-4939-7831-1_22.

PMID:
29851012
46.

Heart rate reduction with ivabradine in the early phase of atherosclerosis is protective in the endothelium of ApoE-deficient mice.

Aquila G, Morelli MB, Vieceli Dalla Sega F, Fortini F, Nigro P, Caliceti C, Ferracin M, Negrini M, Pannuti A, Bonora M, Pinton P, Ferrari R, Rizzo P.

J Physiol Pharmacol. 2018 Feb;69(1):35-52. doi: 10.26402/jpp.2018.1.04. Epub 2018 May 8.

47.

Saccharomyces cerevisiae Boulardii Reduces the Deoxynivalenol-Induced Alteration of the Intestinal Transcriptome.

Alassane-Kpembi I, Pinton P, Hupé JF, Neves M, Lippi Y, Combes S, Castex M, Oswald IP.

Toxins (Basel). 2018 May 15;10(5). pii: E199. doi: 10.3390/toxins10050199.

48.

Ergot Alkaloids at Doses Close to EU Regulatory Limits Induce Alterations of the Liver and Intestine.

Maruo VM, Bracarense AP, Metayer JP, Vilarino M, Oswald IP, Pinton P.

Toxins (Basel). 2018 May 1;10(5). pii: E183. doi: 10.3390/toxins10050183.

49.

PLCB3 Loss of Function Reduces Pseudomonas aeruginosa-Dependent IL-8 Release in Cystic Fibrosis.

Rimessi A, Bezzerri V, Salvatori F, Tamanini A, Nigro F, Dechecchi MC, Santangelo A, Prandini P, Munari S, Provezza L, Garreau de Loubresse N, Muller J, Ribeiro CMP, Lippi G, Gambari R, Pinton P, Cabrini G.

Am J Respir Cell Mol Biol. 2018 Oct;59(4):428-436. doi: 10.1165/rcmb.2017-0267OC.

PMID:
29668297
50.

Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.

Morciano G, Marchi S, Morganti C, Sbano L, Bittremieux M, Kerkhofs M, Corricelli M, Danese A, Karkucinska-Wieckowska A, Wieckowski MR, Bultynck G, Giorgi C, Pinton P.

Neoplasia. 2018 May;20(5):510-523. doi: 10.1016/j.neo.2018.03.005. Epub 2018 Apr 5. Review.

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