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Items: 37


Isolation and Quantification of Zika Virus from Multiple Organs in a Mouse.

Brien JD, Hassert M, Stone ET, Geerling E, Cruz-Orengo L, Pinto AK.

J Vis Exp. 2019 Aug 15;(150). doi: 10.3791/59632.


Identification of Protective CD8 T Cell Responses in a Mouse Model of Zika Virus Infection.

Hassert M, Harris MG, Brien JD, Pinto AK.

Front Immunol. 2019 Jul 17;10:1678. doi: 10.3389/fimmu.2019.01678. eCollection 2019.


Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells.

Hassert M, Brien JD, Pinto AK.

Front Immunol. 2019 May 9;10:1045. doi: 10.3389/fimmu.2019.01045. eCollection 2019. Review.


CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection.

Hassert M, Wolf KJ, Schwetye KE, DiPaolo RJ, Brien JD, Pinto AK.

PLoS Pathog. 2018 Sep 13;14(9):e1007237. doi: 10.1371/journal.ppat.1007237. eCollection 2018 Sep.


Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus.

Pantoja P, Pérez-Guzmán EX, Rodríguez IV, White LJ, González O, Serrano C, Giavedoni L, Hodara V, Cruz L, Arana T, Martínez MI, Hassert MA, Brien JD, Pinto AK, de Silva A, Sariol CA.

Nat Commun. 2017 Jun 23;8:15674. doi: 10.1038/ncomms15674.


Solid-state fermentation for production of a bioherbicide from Diaporthe sp. and its formulation to enhance the efficacy.

Bastos BO, Deobald GA, Brun T, Dal Prá V, Junges E, Kuhn RC, Pinto AK, Mazutti MA.

3 Biotech. 2017 Jun;7(2):135. doi: 10.1007/s13205-017-0751-4. Epub 2017 Jun 8.


Residues in the PB2 and PA genes contribute to the pathogenicity of avian H7N3 influenza A virus in DBA/2 mice.

DesRochers BL, Chen RE, Gounder AP, Pinto AK, Bricker T, Linton CN, Rogers CD, Williams GD, Webby RJ, Boon AC.

Virology. 2016 Jul;494:89-99. doi: 10.1016/j.virol.2016.04.013. Epub 2016 Apr 20.


A North American H7N3 Influenza Virus Supports Reassortment with 2009 Pandemic H1N1 and Induces Disease in Mice without Prior Adaptation.

Williams GD, Pinto AK, Doll B, Boon ACM.

J Virol. 2016 Apr 14;90(9):4796-4806. doi: 10.1128/JVI.02761-15. Print 2016 May.


Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System.

Proenca-Modena JL, Hyde JL, Sesti-Costa R, Lucas T, Pinto AK, Richner JM, Gorman MJ, Lazear HM, Diamond MS.

J Virol. 2015 Oct 14;90(1):189-205. doi: 10.1128/JVI.02276-15. Print 2016 Jan 1.


Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection.

Pinto AK, Brien JD, Lam CY, Johnson S, Chiang C, Hiscott J, Sarathy VV, Barrett AD, Shresta S, Diamond MS.

MBio. 2015 Sep 15;6(5):e01316-15. doi: 10.1128/mBio.01316-15.


Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families.

Pinto AK, Williams GD, Szretter KJ, White JP, Proença-Módena JL, Liu G, Olejnik J, Brien JD, Ebihara H, Mühlberger E, Amarasinghe G, Diamond MS, Boon AC.

J Virol. 2015 Sep;89(18):9465-76. doi: 10.1128/JVI.00996-15. Epub 2015 Jul 8.


Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier.

Lazear HM, Daniels BP, Pinto AK, Huang AC, Vick SC, Doyle SE, Gale M Jr, Klein RS, Diamond MS.

Sci Transl Med. 2015 Apr 22;7(284):284ra59. doi: 10.1126/scitranslmed.aaa4304. Erratum in: Sci Transl Med. 2015 May 27;7(289):289er5.


Oropouche virus infection and pathogenesis are restricted by MAVS, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells.

Proenca-Modena JL, Sesti-Costa R, Pinto AK, Richner JM, Lazear HM, Lucas T, Hyde JL, Diamond MS.

J Virol. 2015 May;89(9):4720-37. doi: 10.1128/JVI.00077-15. Epub 2015 Feb 25.


Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection.

Thackray LB, Shrestha B, Richner JM, Miner JJ, Pinto AK, Lazear HM, Gale M Jr, Diamond MS.

J Virol. 2014 Oct;88(19):11007-21. doi: 10.1128/JVI.01545-14. Epub 2014 Jul 16.


c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells.

Chou C, Pinto AK, Curtis JD, Persaud SP, Cella M, Lin CC, Edelson BT, Allen PM, Colonna M, Pearce EL, Diamond MS, Egawa T.

Nat Immunol. 2014 Sep;15(9):884-93. doi: 10.1038/ni.2943. Epub 2014 Jul 13.


Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis.

Pinto AK, Ramos HJ, Wu X, Aggarwal S, Shrestha B, Gorman M, Kim KY, Suthar MS, Atkinson JP, Gale M Jr, Diamond MS.

PLoS Pathog. 2014 Apr 17;10(4):e1004086. doi: 10.1371/journal.ppat.1004086. eCollection 2014 Apr.


A novel T-cell receptor mimic defines dendritic cells that present an immunodominant West Nile virus epitope in mice.

Kim S, Pinto AK, Myers NB, Hawkins O, Doll K, Kaabinejadian S, Netland J, Bevan MJ, Weidanz JA, Hildebrand WH, Diamond MS, Hansen TH.

Eur J Immunol. 2014 Jul;44(7):1936-46. doi: 10.1002/eji.201444450. Epub 2014 May 3.


Murine norovirus infection does not cause major disruptions in the murine intestinal microbiota.

Nelson AM, Elftman MD, Pinto AK, Baldridge M, Hooper P, Kuczynski J, Petrosino JF, Young VB, Wobus CE.

Microbiome. 2013 Feb 18;1(1):7. doi: 10.1186/2049-2618-1-7.


Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system.

Lazear HM, Pinto AK, Ramos HJ, Vick SC, Shrestha B, Suthar MS, Gale M Jr, Diamond MS.

J Virol. 2013 Nov;87(21):11401-15. doi: 10.1128/JVI.01403-13. Epub 2013 Aug 21.


A hydrogen peroxide-inactivated virus vaccine elicits humoral and cellular immunity and protects against lethal West Nile virus infection in aged mice.

Pinto AK, Richner JM, Poore EA, Patil PP, Amanna IJ, Slifka MK, Diamond MS.

J Virol. 2013 Feb;87(4):1926-36. doi: 10.1128/JVI.02903-12. Epub 2012 Dec 5.


CD8+ T cells use TRAIL to restrict West Nile virus pathogenesis by controlling infection in neurons.

Shrestha B, Pinto AK, Green S, Bosch I, Diamond MS.

J Virol. 2012 Sep;86(17):8937-48. doi: 10.1128/JVI.00673-12. Epub 2012 Jun 27.


RAE1ε ligand expressed on pancreatic islets recruits NKG2D receptor-expressing cytotoxic T cells independent of T cell receptor recognition.

Markiewicz MA, Wise EL, Buchwald ZS, Pinto AK, Zafirova B, Polic B, Shaw AS.

Immunity. 2012 Jan 27;36(1):132-41. doi: 10.1016/j.immuni.2011.11.014. Epub 2012 Jan 12.


A temporal role of type I interferon signaling in CD8+ T cell maturation during acute West Nile virus infection.

Pinto AK, Daffis S, Brien JD, Gainey MD, Yokoyama WM, Sheehan KC, Murphy KM, Schreiber RD, Diamond MS.

PLoS Pathog. 2011 Dec;7(12):e1002407. doi: 10.1371/journal.ppat.1002407. Epub 2011 Dec 1.


Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection.

Schlub TE, Sun JC, Walton SM, Robbins SH, Pinto AK, Munks MW, Hill AB, Brossay L, Oxenius A, Davenport MP.

J Immunol. 2011 Aug 1;187(3):1385-92. doi: 10.4049/jimmunol.1100416. Epub 2011 Jun 22.


Beta interferon controls West Nile virus infection and pathogenesis in mice.

Lazear HM, Pinto AK, Vogt MR, Gale M Jr, Diamond MS.

J Virol. 2011 Jul;85(14):7186-94. doi: 10.1128/JVI.00396-11. Epub 2011 May 4.


The lectin pathway of complement activation contributes to protection from West Nile virus infection.

Fuchs A, Pinto AK, Schwaeble WJ, Diamond MS.

Virology. 2011 Mar 30;412(1):101-9. doi: 10.1016/j.virol.2011.01.003. Epub 2011 Jan 26.


Effects of acute and chronic murine norovirus infections on immune responses and recovery from Friend retrovirus infection.

Ammann CG, Messer RJ, Varvel K, Debuysscher BL, Lacasse RA, Pinto AK, Hasenkrug KJ.

J Virol. 2009 Dec;83(24):13037-41. doi: 10.1128/JVI.01445-09. Epub 2009 Oct 7.


Murine norovirus infection has no significant effect on adaptive immunity to vaccinia virus or influenza A virus.

Hensley SE, Pinto AK, Hickman HD, Kastenmayer RJ, Bennink JR, Virgin HW, Yewdell JW.

J Virol. 2009 Jul;83(14):7357-60. doi: 10.1128/JVI.00623-09. Epub 2009 Apr 29.


The role of NKG2D signaling in inhibition of cytotoxic T-lymphocyte lysis by the Murine cytomegalovirus immunoevasin m152/gp40.

Pinto AK, Jamieson AM, Raulet DH, Hill AB.

J Virol. 2007 Nov;81(22):12564-71. Epub 2007 Sep 12.


Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis.

Pinto AK, Munks MW, Koszinowski UH, Hill AB.

J Immunol. 2006 Sep 1;177(5):3225-34.


Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection.

Munks MW, Cho KS, Pinto AK, Sierro S, Klenerman P, Hill AB.

J Immunol. 2006 Jul 1;177(1):450-8.


Viral interference with antigen presentation to CD8+ T cells: lessons from cytomegalovirus.

Pinto AK, Hill AB.

Viral Immunol. 2005;18(3):434-44. Review.


T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens.

Brehm MA, Pinto AK, Daniels KA, Schneck JP, Welsh RM, Selin LK.

Nat Immunol. 2002 Jul;3(7):627-34. Epub 2002 Jun 3.


Innate immunity to viruses: control of vaccinia virus infection by gamma delta T cells.

Selin LK, Santolucito PA, Pinto AK, Szomolanyi-Tsuda E, Welsh RM.

J Immunol. 2001 Jun 1;166(11):6784-94.


Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses.

Selin LK, Lin MY, Kraemer KA, Pardoll DM, Schneck JP, Varga SM, Santolucito PA, Pinto AK, Welsh RM.

Immunity. 1999 Dec;11(6):733-42.

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