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Items: 1 to 50 of 250

1.

Intratumoral heterogeneity and hypoxia gene expression signatures: Is a single biopsy adequate?

Lukovic J, Han K, Pintilie M, Chaudary N, Hill RP, Fyles A, Milosevic M.

Clin Transl Radiat Oncol. 2019 Oct 3;19:110-115. doi: 10.1016/j.ctro.2019.09.006. eCollection 2019 Nov.

2.

Evaluation of Lymphadenopathy and Suspected Lymphoma in a Lymphoma Rapid Diagnosis Clinic.

Nixon S, Bezverbnaya K, Maganti M, Gullane P, Reedijk M, Kuruvilla J, Prica A, Kridel R, Kukreti V, Bennett S, Rogalla P, Delabie J, Pintilie M, Crump M.

J Oncol Pract. 2019 Oct 1:JOP1900202. doi: 10.1200/JOP.19.00202. [Epub ahead of print]

PMID:
31573831
3.

Correction: Targeting CXCL12/CXCR4 and myeloid cells to improve the therapeutic ratio in patient-derived cervical cancer models treated with radio-chemotherapy.

Lecavalier-Barsoum M, Chaudary N, Han K, Pintilie M, Hill RP, Milosevic M.

Br J Cancer. 2019 Oct;121(7):626. doi: 10.1038/s41416-019-0545-z.

PMID:
31399696
4.

Anaplastic lymphoma kinase 5A4 immunohistochemistry as a diagnostic assay in lung cancer: A Canadian reference testing center's results in population-based reflex testing.

Fiset PO, Labbé C, Young K, Craddock KJ, Smith AC, Tanguay J, Pintilie M, Wang R, Torlakovic E, Cheung C, da Cunha Santos G, Ko HM, Boerner SL, Hwang DM, Leighl NB, Tsao MS.

Cancer. 2019 Nov 15;125(22):4043-4051. doi: 10.1002/cncr.32422. Epub 2019 Aug 7.

PMID:
31390053
5.

Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer.

Wang D, Pham NA, Freeman TM, Raghavan V, Navab R, Chang J, Zhu CQ, Ly D, Tong J, Wouters BG, Pintilie M, Moran MF, Liu G, Shepherd FA, Tsao MS.

Cancers (Basel). 2019 Jul 19;11(7). pii: E1009. doi: 10.3390/cancers11071009.

6.

HPV-independent Vulvar Squamous Cell Carcinoma is Associated With Significantly Worse Prognosis Compared With HPV-associated Tumors.

Allo G, Yap ML, Cuartero J, Milosevic M, Ferguson S, Mackay H, Kamel-Reid S, Weinreb I, Ghazarian D, Pintilie M, Clarke BA.

Int J Gynecol Pathol. 2019 Jul 3. doi: 10.1097/PGP.0000000000000620. [Epub ahead of print]

PMID:
31274700
7.

Targeting CXCL12/CXCR4 and myeloid cells to improve the therapeutic ratio in patient-derived cervical cancer models treated with radio-chemotherapy.

Lecavalier-Barsoum M, Chaudary N, Han K, Pintilie M, Hill RP, Milosevic M.

Br J Cancer. 2019 Jul;121(3):249-256. doi: 10.1038/s41416-019-0497-3. Epub 2019 Jun 26. Erratum in: Br J Cancer. 2019 Aug 9;:.

PMID:
31239542
8.

Repeatability and reproducibility of MRI-based radiomic features in cervical cancer.

Fiset S, Welch ML, Weiss J, Pintilie M, Conway JL, Milosevic M, Fyles A, Traverso A, Jaffray D, Metser U, Xie J, Han K.

Radiother Oncol. 2019 Jun;135:107-114. doi: 10.1016/j.radonc.2019.03.001. Epub 2019 Mar 19.

PMID:
31015155
9.

Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion.

Hao J, Zeltz C, Pintilie M, Li Q, Sakashita S, Wang T, Cabanero M, Martins-Filho SN, Wang DY, Pasko E, Venkat K, Joseph J, Raghavan V, Zhu CQ, Wang YH, Moghal N, Tsao MS, Navab R.

Neoplasia. 2019 May;21(5):482-493. doi: 10.1016/j.neo.2019.03.009. Epub 2019 Apr 9.

10.

Meningioma Screening With MRI in Childhood Leukemia Survivors Treated With Cranial Radiation.

Co JL, Swain M, Murray LJ, Ahmed S, Laperriere NJ, Tsang DS, Yu E, Pintilie M, Weiss J, Hodgson DC.

Int J Radiat Oncol Biol Phys. 2019 Jul 1;104(3):640-643. doi: 10.1016/j.ijrobp.2019.02.057. Epub 2019 Mar 14.

PMID:
30880270
11.

Effect of Coexisting KRAS and TP53 Mutations in Patients Treated With Chemotherapy for Non-small-cell Lung Cancer.

Tomasini P, Mascaux C, Jao K, Labbe C, Kamel-Reid S, Stockley T, Hwang DM, Leighl NB, Liu G, Bradbury PA, Pintilie M, Tsao MS, Shepherd FA.

Clin Lung Cancer. 2019 May;20(3):e338-e345. doi: 10.1016/j.cllc.2018.12.009. Epub 2018 Dec 19.

PMID:
30770327
12.

Systemic Therapy Use and Outcomes After Relapse from Preoperative Radiation and Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma.

Soldera SV, Kavanagh J, Pintilie M, Leighl NB, de Perrot M, Cho J, Hope A, Feld R, Bradbury PA.

Oncologist. 2019 Jul;24(7):e510-e517. doi: 10.1634/theoncologist.2018-0501. Epub 2018 Nov 26.

PMID:
30478189
13.

Genomic Classifier for Guiding Treatment of Intermediate-Risk Prostate Cancers to Dose-Escalated Image Guided Radiation Therapy Without Hormone Therapy.

Berlin A, Murgic J, Hosni A, Pintilie M, Salcedo A, Fraser M, Kamel-Reid S, Zhang J, Wang Q, Ch'ng C, Deheshi S, Davicioni E, van der Kwast T, Boutros PC, Bristow RG, Chua MLK.

Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):84-91. doi: 10.1016/j.ijrobp.2018.08.030. Epub 2018 Aug 29.

14.

The prognostic effect of single and multiple cancer-related somatic mutations in resected non-small-cell lung cancer.

Jao K, Tomasini P, Kamel-Reid S, Korpanty GJ, Mascaux C, Sakashita S, Labbé C, Leighl NB, Liu G, Feld R, Bradbury PA, Hwang DM, Pintilie M, Tsao MS, Shepherd FA.

Lung Cancer. 2018 Sep;123:22-29. doi: 10.1016/j.lungcan.2018.06.023. Epub 2018 Jun 19.

PMID:
30089591
15.

Lung cancer in never smokers from the Princess Margaret Cancer Centre.

Korpanty GJ, Kamel-Reid S, Pintilie M, Hwang DM, Zer A, Liu G, Leighl NB, Feld R, Siu LL, Bedard PL, Tsao MS, Shepherd FA.

Oncotarget. 2018 Apr 27;9(32):22559-22570. doi: 10.18632/oncotarget.25176. eCollection 2018 Apr 27.

16.

PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 Project.

Tsao MS, Kerr KM, Kockx M, Beasley MB, Borczuk AC, Botling J, Bubendorf L, Chirieac L, Chen G, Chou TY, Chung JH, Dacic S, Lantuejoul S, Mino-Kenudson M, Moreira AL, Nicholson AG, Noguchi M, Pelosi G, Poleri C, Russell PA, Sauter J, Thunnissen E, Wistuba I, Yu H, Wynes MW, Pintilie M, Yatabe Y, Hirsch FR.

J Thorac Oncol. 2018 Sep;13(9):1302-1311. doi: 10.1016/j.jtho.2018.05.013. Epub 2018 May 22.

17.

Measurement of Tumor Hypoxia in Patients With Locally Advanced Cervical Cancer Using Positron Emission Tomography with 18F-Fluoroazomyin Arabinoside.

Han K, Shek T, Vines D, Driscoll B, Fyles A, Jaffray D, Keller H, Metser U, Pintilie M, Xie J, Yeung I, Milosevic M.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1202-1209. doi: 10.1016/j.ijrobp.2018.02.030. Epub 2018 Mar 2.

PMID:
29680257
18.

Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC).

Dhont L, Pintilie M, Kaufman E, Navab R, Tam S, Burny A, Shepherd F, Belayew A, Tsao MS, Mascaux C.

BMC Cancer. 2018 Apr 16;18(1):429. doi: 10.1186/s12885-018-4215-y.

19.

The predictive value of nadir neutrophil count during treatment of cervical cancer: Interactions with tumor hypoxia and interstitial fluid pressure (IFP).

Glicksman R, Chaudary N, Pintilie M, Leung E, Clarke B, Sy K, Hill RP, Han K, Fyles A, Milosevic M.

Clin Transl Radiat Oncol. 2017 Sep 15;6:15-20. doi: 10.1016/j.ctro.2017.08.002. eCollection 2017 Oct.

20.

Prognostic Significance of Human Papilloma Virus and p16 Expression in Patients with Vulvar Squamous Cell Carcinoma who Received Radiotherapy.

Yap ML, Allo G, Cuartero J, Pintilie M, Kamel-Reid S, Murphy J, Mackay H, Clarke B, Fyles A, Milosevic M.

Clin Oncol (R Coll Radiol). 2018 Apr;30(4):254-261. doi: 10.1016/j.clon.2018.01.011. Epub 2018 Feb 12.

PMID:
29449057
21.

Role of Magnetic Resonance Imaging Targeted Biopsy in Detection of Prostate Cancer Harboring Adverse Pathological Features of Intraductal Carcinoma and Invasive Cribriform Carcinoma.

Prendeville S, Gertner M, Maganti M, Pintilie M, Perlis N, Toi A, Evans AJ, Finelli A, van der Kwast TH, Ghai S.

J Urol. 2018 Jul;200(1):104-113. doi: 10.1016/j.juro.2018.01.081. Epub 2018 Feb 2.

PMID:
29408568
22.

Long-Term Outcomes of Phase 1 and 2 Studies of SBRT for Hepatic Colorectal Metastases.

McPartlin A, Swaminath A, Wang R, Pintilie M, Brierley J, Kim J, Ringash J, Wong R, Dinniwell R, Craig T, Dawson LA.

Int J Radiat Oncol Biol Phys. 2017 Oct 1;99(2):388-395. doi: 10.1016/j.ijrobp.2017.04.010. Epub 2017 Apr 13.

PMID:
28871989
23.

Prognostic and predictive effects of TP53 co-mutation in patients with EGFR-mutated non-small cell lung cancer (NSCLC).

Labbé C, Cabanero M, Korpanty GJ, Tomasini P, Doherty MK, Mascaux C, Jao K, Pitcher B, Wang R, Pintilie M, Leighl NB, Feld R, Liu G, Bradbury PA, Kamel-Reid S, Tsao MS, Shepherd FA.

Lung Cancer. 2017 Sep;111:23-29. doi: 10.1016/j.lungcan.2017.06.014. Epub 2017 Jun 24.

PMID:
28838393
24.

A Prostate Cancer "Nimbosus": Genomic Instability and SChLAP1 Dysregulation Underpin Aggression of Intraductal and Cribriform Subpathologies.

Chua MLK, Lo W, Pintilie M, Murgic J, Lalonde E, Bhandari V, Mahamud O, Gopalan A, Kweldam CF, van Leenders GJLH, Verhoef EI, Hoogland AM, Livingstone J, Berlin A, Dal Pra A, Meng A, Zhang J, Orain M, Picard V, Hovington H, Bergeron A, Lacombe L, Fradet Y, Têtu B, Reuter VE, Fleshner N, Fraser M, Boutros PC, van der Kwast TH, Bristow RG.

Eur Urol. 2017 Nov;72(5):665-674. doi: 10.1016/j.eururo.2017.04.034. Epub 2017 May 13.

PMID:
28511883
25.

Improved outcomes with dose escalation in localized prostate cancer treated with precision image-guided radiotherapy.

Raziee H, Moraes FY, Murgic J, Chua MLK, Pintilie M, Chung P, Ménard C, Bayley A, Gospodarowicz M, Warde P, Craig T, Catton C, Bristow RG, Jaffray DA, Berlin A.

Radiother Oncol. 2017 Jun;123(3):459-465. doi: 10.1016/j.radonc.2017.04.003. Epub 2017 Apr 20.

PMID:
28434799
26.

Human tissue Kallikreins: Blood levels and response to radiotherapy in intermediate risk prostate cancer.

Nasser NJ, Thoms J, Soosaipillai A, Pintilie M, Wang R, Diamandis EP, Bristow RG.

Radiother Oncol. 2017 Sep;124(3):427-432. doi: 10.1016/j.radonc.2017.03.023. Epub 2017 Apr 17.

PMID:
28427756
27.

Hazards and incidents: Detection and learning in radiation medicine, a comparison of 2 educational interventions.

Thompson R, Lu Y, Potvin M, Holmes J, Di Prospero L, Keller B, Szumacher E, Liszewski B, Catton P, Giuliani M, Pitcher B, Pintilie M, Bissonnette JP.

Pract Radiat Oncol. 2017 Nov - Dec;7(6):e431-e438. doi: 10.1016/j.prro.2017.02.006. Epub 2017 Feb 27.

PMID:
28377137
28.

Treatment options for patients with brain metastases from EGFR/ALK-driven lung cancer.

Doherty MK, Korpanty GJ, Tomasini P, Alizadeh M, Jao K, Labbé C, Mascaux CM, Martin P, Kamel-Reid S, Tsao MS, Pintilie M, Liu G, Bradbury PA, Feld R, Leighl NB, Chung C, Shepherd FA.

Radiother Oncol. 2017 May;123(2):195-202. doi: 10.1016/j.radonc.2017.03.007. Epub 2017 Mar 28.

PMID:
28363487
29.

Interferon β-1a for the treatment of Ebola virus disease: A historically controlled, single-arm proof-of-concept trial.

Konde MK, Baker DP, Traore FA, Sow MS, Camara A, Barry AA, Mara D, Barry A, Cone M, Kaba I, Richard AA, Beavogui AH, Günther S; European Mobile Laboratory Consortium, Pintilie M, Fish EN.

PLoS One. 2017 Feb 22;12(2):e0169255. doi: 10.1371/journal.pone.0169255. eCollection 2017. Erratum in: PLoS One. 2017 Apr 12;12 (4):e0175930.

30.

Assessment of a prognostic model, PSA metrics and toxicities in metastatic castrate resistant prostate cancer using data from Project Data Sphere (PDS).

Pitcher B, Khoja L, Hamilton RJ, Abdallah K, Pintilie M, Joshua AM.

PLoS One. 2017 Feb 2;12(2):e0170544. doi: 10.1371/journal.pone.0170544. eCollection 2017.

31.

The impact of active breathing control on internal mammary lymph node coverage and normal tissue exposure in breast cancer patients planned for left-sided postmastectomy radiation therapy.

Barry A, Rock K, Sole C, Rahman M, Pintilie M, Lee G, Fyles A, Koch CA.

Pract Radiat Oncol. 2017 Jul - Aug;7(4):228-233. doi: 10.1016/j.prro.2016.11.010. Epub 2016 Dec 7.

PMID:
28139424
32.

FGFR4 polymorphic alleles modulate mitochondrial respiration: A novel target for somatostatin analog action in pituitary tumors.

Ezzat S, Wang R, Pintilie M, Asa SL.

Oncotarget. 2017 Jan 10;8(2):3481-3494. doi: 10.18632/oncotarget.13843.

33.

MATE2 Expression Is Associated with Cancer Cell Response to Metformin.

Chowdhury S, Yung E, Pintilie M, Muaddi H, Chaib S, Yeung M, Fusciello M, Sykes J, Pitcher B, Hagenkort A, McKee T, Vellanki R, Chen E, Bristow RG, Wouters BG, Koritzinsky M.

PLoS One. 2016 Dec 13;11(12):e0165214. doi: 10.1371/journal.pone.0165214. eCollection 2016.

34.

Activity of the novel polo-like kinase 4 inhibitor CFI-400945 in pancreatic cancer patient-derived xenografts.

Lohse I, Mason J, Cao PM, Pintilie M, Bray M, Hedley DW.

Oncotarget. 2017 Jan 10;8(2):3064-3071. doi: 10.18632/oncotarget.13619.

35.

Hedgehog inhibition enhances efficacy of radiation and cisplatin in orthotopic cervical cancer xenografts.

Chaudary N, Pintilie M, Hedley D, Hill RP, Milosevic M, Mackay H.

Br J Cancer. 2017 Jan 3;116(1):50-57. doi: 10.1038/bjc.2016.383. Epub 2016 Nov 22.

36.

Long-term outcomes of a phase II trial of moderate hypofractionated image-guided intensity modulated radiotherapy (IG-IMRT) for localized prostate cancer.

Lieng H, Pintilie M, Bayley A, Berlin A, Bristow R, Chung P, Gospodarowicz M, Huang R, Ménard C, Warde P, Catton C.

Radiother Oncol. 2017 Jan;122(1):93-98. doi: 10.1016/j.radonc.2016.10.017. Epub 2016 Nov 9.

PMID:
27838147
37.

Translating a Prognostic DNA Genomic Classifier into the Clinic: Retrospective Validation in 563 Localized Prostate Tumors.

Lalonde E, Alkallas R, Chua MLK, Fraser M, Haider S, Meng A, Zheng J, Yao CQ, Picard V, Orain M, Hovington H, Murgic J, Berlin A, Lacombe L, Bergeron A, Fradet Y, Têtu B, Lindberg J, Egevad L, Grönberg H, Ross-Adams H, Lamb AD, Halim S, Dunning MJ, Neal DE, Pintilie M, van der Kwast T, Bristow RG, Boutros PC.

Eur Urol. 2017 Jul;72(1):22-31. doi: 10.1016/j.eururo.2016.10.013. Epub 2016 Nov 1.

PMID:
27815082
38.

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.

Wang D, Pham NA, Tong J, Sakashita S, Allo G, Kim L, Yanagawa N, Raghavan V, Wei Y, To C, Trinh QM, Starmans MH, Chan-Seng-Yue MA, Chadwick D, Li L, Zhu CQ, Liu N, Li M, Lee S, Ignatchenko V, Strumpf D, Taylor P, Moghal N, Liu G, Boutros PC, Kislinger T, Pintilie M, Jurisica I, Shepherd FA, McPherson JD, Muthuswamy L, Moran MF, Tsao MS.

Int J Cancer. 2017 Feb 1;140(3):662-673. doi: 10.1002/ijc.30472. Epub 2016 Nov 7.

39.

Phase 1/2 Study of the Addition of Cisplatin to Adjuvant Chemotherapy With Image Guided High-Precision Radiation Therapy for Completely Resected Gastric Cancer.

Goody RB, MacKay H, Pitcher B, Oza A, Siu LL, Kim J, Wong RK, Chen E, Swallow C, Knox J, Kassam Z, Cummings B, Feld R, Hedley D, Liu G, Krzyzanowska MK, Dinniwell R, Brade AM, Dawson LA, Pintilie M, Ringash J.

Int J Radiat Oncol Biol Phys. 2016 Dec 1;96(5):994-1002. doi: 10.1016/j.ijrobp.2016.08.034. Epub 2016 Aug 31.

PMID:
27745984
40.

Plerixafor Improves Primary Tumor Response and Reduces Metastases in Cervical Cancer Treated with Radio-Chemotherapy.

Chaudary N, Pintilie M, Jelveh S, Lindsay P, Hill RP, Milosevic M.

Clin Cancer Res. 2017 Mar 1;23(5):1242-1249. doi: 10.1158/1078-0432.CCR-16-1730. Epub 2016 Oct 3.

41.

Patient-Derived Xenograft Establishment from Human Malignant Pleural Mesothelioma.

Wu L, Allo G, John T, Li M, Tagawa T, Opitz I, Anraku M, Yun Z, Pintilie M, Pitcher B, Liu G, Feld R, Johnston MR, de Perrot M, Tsao MS.

Clin Cancer Res. 2017 Feb 15;23(4):1060-1067. doi: 10.1158/1078-0432.CCR-16-0844. Epub 2016 Sep 28.

42.

Hypoxia Marker GLUT-1 (Glucose Transporter 1) is an Independent Prognostic Factor for Survival in Bladder Cancer Patients Treated with Radical Cystectomy.

Boström PJ, Thoms J, Sykes J, Ahmed O, Evans A, van Rhijn BW, Mirtti T, Stakhovskyi O, Laato M, Margel D, Pintilie M, Kuk C, Milosevic M, Zlotta AR, Bristow RG.

Bladder Cancer. 2016 Jan 7;2(1):101-109.

43.

Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302.

Lohse I, Rasowski J, Cao P, Pintilie M, Do T, Tsao MS, Hill RP, Hedley DW.

Oncotarget. 2016 Jun 7;7(23):33571-80. doi: 10.18632/oncotarget.9654.

44.

PMH 9907: Long-term outcomes of a randomized phase 3 study of short-term bicalutamide hormone therapy and dose-escalated external-beam radiation therapy for localized prostate cancer.

McPartlin AJ, Glicksman R, Pintilie M, Tsuji D, Mok G, Bayley A, Chung P, Bristow RG, Gospodarowicz MK, Catton CN, Milosevic M, Warde PR.

Cancer. 2016 Aug 15;122(16):2595-603. doi: 10.1002/cncr.30093. Epub 2016 May 24.

45.

MiR-449a promotes breast cancer progression by targeting CRIP2.

Shi W, Bruce J, Lee M, Yue S, Rowe M, Pintilie M, Kogo R, Bissey PA, Fyles A, Yip KW, Liu FF.

Oncotarget. 2016 Apr 5;7(14):18906-18. doi: 10.18632/oncotarget.7753.

46.

Changes in plasma biomarkers following treatment with cabozantinib in metastatic castration-resistant prostate cancer: a post hoc analysis of an extension cohort of a phase II trial.

Leibowitz-Amit R, Pintilie M, Khoja L, Azad AA, Berger R, Laird AD, Aftab DT, Chi KN, Joshua AM.

J Transl Med. 2016 Jan 13;14:12. doi: 10.1186/s12967-015-0747-y.

47.

Survival Analysis in the Presence of Competing Risks: The Example of Waitlisted Kidney Transplant Candidates.

Sapir-Pichhadze R, Pintilie M, Tinckam KJ, Laupacis A, Logan AG, Beyene J, Kim SJ.

Am J Transplant. 2016 Jul;16(7):1958-66. doi: 10.1111/ajt.13717. Epub 2016 Mar 3. Review.

48.

A proposal for cellularity assessment for EGFR mutational analysis with a correlation with DNA yield and evaluation of the number of sections obtained from cell blocks for immunohistochemistry in non-small cell lung carcinoma.

da Cunha Santos G, Wyeth T, Reid A, Saieg MA, Pitcher B, Pintilie M, Kamel-Reid S, Tsao MS.

J Clin Pathol. 2016 Jul;69(7):607-11. doi: 10.1136/jclinpath-2015-203437. Epub 2016 Jan 5.

PMID:
26733659
49.

Association between Metformin Use and Mortality after Cervical Cancer in Older Women with Diabetes.

Han K, Pintilie M, Lipscombe LL, Lega IC, Milosevic MF, Fyles AW.

Cancer Epidemiol Biomarkers Prev. 2016 Mar;25(3):507-12. doi: 10.1158/1055-9965.EPI-15-1008. Epub 2015 Dec 31.

50.

Progression to Stage 4 chronic kidney disease and death, acute kidney injury and hospitalization risk: a retrospective cohort study.

Sud M, Tangri N, Pintilie M, Levey AS, Naimark DM.

Nephrol Dial Transplant. 2016 Jul;31(7):1122-30. doi: 10.1093/ndt/gfv389. Epub 2015 Nov 20.

PMID:
26590389

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