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Cardiorenal AL amyloidosis: risk stratification and outcomes based upon cardiac and renal biomarkers.

Rezk T, Lachmann HJ, Fontana M, Naharro AM, Sachchithanantham S, Mahmood S, Petrie A, Whelan CJ, Pinney JH, Foard D, Lane T, Youngstein T, Wechalekar AD, Hawkins PN, Gillmore JD.

Br J Haematol. 2019 Aug;186(3):460-470. doi: 10.1111/bjh.15955. Epub 2019 May 24.


Bioimpedance vector analysis for the detection of extracellular volume overload and sarcopenia in systemic AL amyloidosis.

Rezk T, Davenport A, Gan JJ, Lachmann HJ, Fontana M, Martinez-Naharro A, Sachchithanantham S, Guillotte C, Mahmood S, Petrie A, Whelan CJ, Pinney JH, Foard D, Lane T, Youngstein T, Wechalekar AD, Hawkins PN, Gillmore JD.

Br J Haematol. 2019 Jun;185(5):977-980. doi: 10.1111/bjh.15675. Epub 2018 Nov 18. No abstract available.


Successful Renal Outcome in Membranoproliferative Glomerulonephritis Following Treatment of the Underlying Subtle Clone: A Case Report.

Rana R, Cockwell P, Vydianath B, Cook M, Pratt G, Drayson MT, Pinney JH.

Mayo Clin Proc Innov Qual Outcomes. 2018 Jun 5;2(3):297-302. doi: 10.1016/j.mayocpiqo.2018.04.003. eCollection 2018 Sep.


Serum free light chain levels and renal function at diagnosis in patients with multiple myeloma.

Yadav P, Cockwell P, Cook M, Pinney J, Giles H, Aung YS, Cairns D, Owen RG, Davies FE, Jackson GH, Child JA, Morgan GJ, Drayson MT.

BMC Nephrol. 2018 Jul 13;19(1):178. doi: 10.1186/s12882-018-0962-x.


CD8 Follicular T Cells Promote B Cell Antibody Class Switch in Autoimmune Disease.

Valentine KM, Davini D, Lawrence TJ, Mullins GN, Manansala M, Al-Kuhlani M, Pinney JM, Davis JK, Beaudin AE, Sindi SS, Gravano DM, Hoyer KK.

J Immunol. 2018 Jul 1;201(1):31-40. doi: 10.4049/jimmunol.1701079. Epub 2018 May 9.


Facing the facts: The Runx2 gene is associated with variation in facial morphology in primates.

Ritzman TB, Banovich N, Buss KP, Guida J, Rubel MA, Pinney J, Khang B, Ravosa MJ, Stone AC.

J Hum Evol. 2017 Oct;111:139-151. doi: 10.1016/j.jhevol.2017.06.014. Epub 2017 Aug 9.


Protein-Protein Interactions in Virus-Host Systems.

Brito AF, Pinney JW.

Front Microbiol. 2017 Aug 17;8:1557. doi: 10.3389/fmicb.2017.01557. eCollection 2017. Review.


Prolonged renal survival in light chain amyloidosis: speed and magnitude of light chain reduction is the crucial factor.

Rezk T, Lachmann HJ, Fontana M, Sachchithanantham S, Mahmood S, Petrie A, Whelan CJ, Pinney JH, Foard D, Lane T, Youngstein T, Wechalekar AD, Bass P, Hawkins PN, Gillmore JD.

Kidney Int. 2017 Dec;92(6):1476-1483. doi: 10.1016/j.kint.2017.05.004. Epub 2017 Jul 18.


Multiple myeloma can be accurately diagnosed in acute kidney injury patients using a rapid serum free light chain test.

Heaney JLJ, Campbell JP, Yadav P, Griffin AE, Shemar M, Pinney JH, Drayson MT.

BMC Nephrol. 2017 Jul 20;18(1):247. doi: 10.1186/s12882-017-0661-z.


Changing epidemiology of AA amyloidosis: clinical observations over 25 years at a single national referral centre.

Lane T, Pinney JH, Gilbertson JA, Hutt DF, Rowczenio DM, Mahmood S, Sachchithanantham S, Fontana M, Youngstein T, Quarta CC, Wechalekar AD, Gillmore JD, Hawkins PN, Lachmann HJ.

Amyloid. 2017 Sep;24(3):162-166. doi: 10.1080/13506129.2017.1342235. Epub 2017 Jul 7.


Increased fracture risk in plasma cell dyscrasias is associated with poorer overall survival.

McIlroy G, Mytton J, Evison F, Yadav P, Drayson MT, Cook M, Pratt G, Cockwell P, Pinney JH.

Br J Haematol. 2017 Oct;179(1):61-65. doi: 10.1111/bjh.14815. Epub 2017 Jun 27.


A population-based study of the impact of dialysis on mortality in multiple myeloma.

Evison F, Sangha J, Yadav P, Aung YS, Sharif A, Pinney JA, Drayson MT, Cook M, Cockwell P.

Br J Haematol. 2018 Feb;180(4):588-591. doi: 10.1111/bjh.14394. Epub 2016 Oct 21. No abstract available.


Uterine artery pulsatility and resistivity indices in pregnancy: Comparison of MRI and Doppler US.

Hawkes RA, Patterson AJ, Priest AN, Harrison G, Hunter S, Pinney J, Set P, Hilliard N, Graves MJ, Smith GC, Lomas DJ.

Placenta. 2016 Jul;43:35-40. doi: 10.1016/j.placenta.2016.04.002. Epub 2016 Apr 6.


Patients with multiple myeloma have excellent long-term outcomes after recovery from dialysis-dependent acute kidney injury.

Yadav P, Hutchison CA, Basnayake K, Stringer S, Jesky M, Fifer L, Snell K, Pinney J, Drayson MT, Cook M, Cockwell P.

Eur J Haematol. 2016 Jun;96(6):610-7. doi: 10.1111/ejh.12644. Epub 2015 Sep 16.


PathwayBooster: a tool to support the curation of metabolic pathways.

Liberal R, Lisowska BK, Leak DJ, Pinney JW.

BMC Bioinformatics. 2015 Mar 15;16:86. doi: 10.1186/s12859-014-0447-2.


Localized delivery of mechano-growth factor E-domain peptide via polymeric microstructures improves cardiac function following myocardial infarction.

Peña JR, Pinney JR, Ayala P, Desai TA, Goldspink PH.

Biomaterials. 2015 Apr;46:26-34. doi: 10.1016/j.biomaterials.2014.12.050. Epub 2015 Jan 16.


Oculoleptomeningeal Amyloidosis associated with transthyretin Leu12Pro in an African patient.

McColgan P, Viegas S, Gandhi S, Bull K, Tudor R, Sheikh F, Pinney J, Fontana M, Rowczenio D, Gillmore JD, Gilbertson JA, Whelan CJ, Shah S, Jaunmuktane Z, Holton JL, Schott JM, Werring DJ, Hawkins PN, Reilly MM.

J Neurol. 2015 Jan;262(1):228-34. doi: 10.1007/s00415-014-7594-2. Epub 2014 Dec 9.


Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding.

Cerchiari A, Garbe JC, Todhunter ME, Jee NY, Pinney JR, LaBarge MA, Desai TA, Gartner ZJ.

Tissue Eng Part C Methods. 2015 Jun;21(6):541-7. doi: 10.1089/ten.TEC.2014.0450. Epub 2014 Dec 11.


Stringent patient selection improves outcomes in systemic light-chain amyloidosis after autologous stem cell transplantation in the upfront and relapsed setting.

Venner CP, Gillmore JD, Sachchithanantham S, Mahmood S, Lane T, Foard D, Roussel M, Rannigan L, Gibbs SDj, Pinney JH, Whelan CJ, Lachmann HJ, Hawkins PN, Wechalekar AD.

Haematologica. 2014 Dec;99(12):e260-3. doi: 10.3324/haematol.2014.108191. Epub 2014 Sep 5. No abstract available.


Novel functionalization of discrete polymeric biomaterial microstructures for applications in imaging and three-dimensional manipulation.

Pinney JR, Melkus G, Cerchiari A, Hawkins J, Desai TA.

ACS Appl Mater Interfaces. 2014 Aug 27;6(16):14477-85. doi: 10.1021/am503778t. Epub 2014 Jul 28.


Discrete microstructural cues for the attenuation of fibrosis following myocardial infarction.

Pinney JR, Du KT, Ayala P, Fang Q, Sievers RE, Chew P, Delrosario L, Lee RJ, Desai TA.

Biomaterials. 2014 Oct;35(31):8820-8828. doi: 10.1016/j.biomaterials.2014.07.005. Epub 2014 Jul 18.


A matched comparison of cyclophosphamide, bortezomib and dexamethasone (CVD) versus risk-adapted cyclophosphamide, thalidomide and dexamethasone (CTD) in AL amyloidosis.

Venner CP, Gillmore JD, Sachchithanantham S, Mahmood S, Lane T, Foard D, Rannigan L, Gibbs SD, Pinney JH, Whelan CJ, Lachmann HJ, Hawkins PN, Wechalekar AD.

Leukemia. 2014 Dec;28(12):2304-10. doi: 10.1038/leu.2014.218. Epub 2014 Jul 16.


Lenalidomide and dexamethasone for systemic AL amyloidosis following prior treatment with thalidomide or bortezomib regimens.

Mahmood S, Venner CP, Sachchithanantham S, Lane T, Rannigan L, Foard D, Pinney JH, Gibbs SD, Whelan CJ, Lachmann HJ, Gillmore JD, Hawkins PN, Wechalekar AD.

Br J Haematol. 2014 Sep;166(6):842-8. doi: 10.1111/bjh.12973. Epub 2014 Jun 13.


Sustained delivery of MGF peptide from microrods attracts stem cells and reduces apoptosis of myocytes.

Doroudian G, Pinney J, Ayala P, Los T, Desai TA, Russell B.

Biomed Microdevices. 2014 Oct;16(5):705-15. doi: 10.1007/s10544-014-9875-z.


Derivative processes for modelling metabolic fluxes.

Zurauskienė J, Kirk P, Thorne T, Pinney J, Stumpf M.

Bioinformatics. 2014 Jul 1;30(13):1892-8. doi: 10.1093/bioinformatics/btu069. Epub 2014 Feb 26.


CMR-based differentiation of AL and ATTR cardiac amyloidosis.

Dungu JN, Valencia O, Pinney JH, Gibbs SD, Rowczenio D, Gilbertson JA, Lachmann HJ, Wechalekar A, Gillmore JD, Whelan CJ, Hawkins PN, Anderson LJ.

JACC Cardiovasc Imaging. 2014 Feb;7(2):133-42. doi: 10.1016/j.jcmg.2013.08.015. Epub 2014 Jan 8.


Analysis of metabolic evolution in bacteria using whole-genome metabolic models.

Bryant WA, Faruqi AA, Pinney JW.

J Comput Biol. 2013 Oct;20(10):755-64. doi: 10.1089/cmb.2013.0079. Epub 2013 Aug 31.


Deciphering the response of Mycobacterium smegmatis to nitrogen stress using bipartite active modules.

Williams KJ, Bryant WA, Jenkins VA, Barton GR, Witney AA, Pinney JW, Robertson BD.

BMC Genomics. 2013 Jul 2;14:436. doi: 10.1186/1471-2164-14-436.


Simple topological properties predict functional misannotations in a metabolic network.

Liberal R, Pinney JW.

Bioinformatics. 2013 Jul 1;29(13):i154-61. doi: 10.1093/bioinformatics/btt236.


Clinical profile and treatment outcomes of immunoglobulin D associated AL amyloidosis.

Roussel M, Sachchithanantham S, Gibbs SD, Venner CP, Pinney JH, Gillmore JD, Lachmann HJ, Hawkins PN, Wechalekar AD.

Br J Haematol. 2013 Sep;162(6):856-8. doi: 10.1111/bjh.12433. Epub 2013 Jun 18. No abstract available.


Modular biological function is most effectively captured by combining molecular interaction data types.

Ames RM, Macpherson JI, Pinney JW, Lovell SC, Robertson DL.

PLoS One. 2013 May 3;8(5):e62670. doi: 10.1371/journal.pone.0062670. Print 2013.


Senile systemic amyloidosis: clinical features at presentation and outcome.

Pinney JH, Whelan CJ, Petrie A, Dungu J, Banypersad SM, Sattianayagam P, Wechalekar A, Gibbs SD, Venner CP, Wassef N, McCarthy CA, Gilbertson JA, Rowczenio D, Hawkins PN, Gillmore JD, Lachmann HJ.

J Am Heart Assoc. 2013 Apr 22;2(2):e000098. doi: 10.1161/JAHA.113.000098.


AMBIENT: Active Modules for Bipartite Networks--using high-throughput transcriptomic data to dissect metabolic response.

Bryant WA, Sternberg MJ, Pinney JW.

BMC Syst Biol. 2013 Mar 25;7:26. doi: 10.1186/1752-0509-7-26.


Systemic amyloidosis in England: an epidemiological study.

Pinney JH, Smith CJ, Taube JB, Lachmann HJ, Venner CP, Gibbs SD, Dungu J, Banypersad SM, Wechalekar AD, Whelan CJ, Hawkins PN, Gillmore JD.

Br J Haematol. 2013 May;161(4):525-32. doi: 10.1111/bjh.12286. Epub 2013 Mar 11.


Digital necrosis from dandelion tea.

Moriarty B, Pinney JH, Owen-Casey MP, Rustin MH, Deroide F, Laing C, Davenport A.

Br J Dermatol. 2013 Jul;169(1):227-30. doi: 10.1111/bjd.12288. No abstract available.


Inflammatory bowel disease and systemic AA amyloidosis.

Sattianayagam PT, Gillmore JD, Pinney JH, Gibbs SD, Wechalekar AD, Gilbertson JA, Rowczenio D, Hawkins PN, Lachmann HJ.

Dig Dis Sci. 2013 Jun;58(6):1689-97. doi: 10.1007/s10620-012-2549-x. Epub 2013 Jan 31.


Systemic AA amyloidosis.

Pinney JH, Lachmann HJ.

Subcell Biochem. 2012;65:541-64. doi: 10.1007/978-94-007-5416-4_20. Review.


Quantification of myocardial extracellular volume fraction in systemic AL amyloidosis: an equilibrium contrast cardiovascular magnetic resonance study.

Banypersad SM, Sado DM, Flett AS, Gibbs SD, Pinney JH, Maestrini V, Cox AT, Fontana M, Whelan CJ, Wechalekar AD, Hawkins PN, Moon JC.

Circ Cardiovasc Imaging. 2013 Jan 1;6(1):34-9. doi: 10.1161/CIRCIMAGING.112.978627. Epub 2012 Nov 28.


Renal transplantation in systemic amyloidosis-importance of amyloid fibril type and precursor protein abundance.

Pinney JH, Lachmann HJ, Sattianayagam PT, Gibbs SD, Wechalekar AD, Venner CP, Whelan CJ, Gilbertson JA, Rowczenio D, Hawkins PN, Gillmore JD.

Am J Transplant. 2013 Feb;13(2):433-41. doi: 10.1111/j.1600-6143.2012.04326.x. Epub 2012 Nov 21.


A prospective study of nutritional status in immunoglobulin light chain amyloidosis.

Sattianayagam PT, Lane T, Fox Z, Petrie A, Gibbs SD, Pinney JH, Risom SS, Rowczenio DM, Wechalekar AD, Lachmann HJ, Gilbertson JA, Hawkins PN, Gillmore JD.

Haematologica. 2013 Jan;98(1):136-40. doi: 10.3324/haematol.2012.070359. Epub 2012 Sep 14.


Evolutionary characteristics of bacterial two-component systems.

Sheng X, Huvet M, Pinney JW, Stumpf MP.

Adv Exp Med Biol. 2012;751:121-37. doi: 10.1007/978-1-4614-3567-9_6.


The electrocardiographic features associated with cardiac amyloidosis of variant transthyretin isoleucine 122 type in Afro-Caribbean patients.

Dungu J, Sattianayagam PT, Whelan CJ, Gibbs SD, Pinney JH, Banypersad SM, Rowczenio D, Gilbertson JA, Lachmann HJ, Wechalekar A, Gillmore JD, Hawkins PN, Anderson LJ.

Am Heart J. 2012 Jul;164(1):72-9. doi: 10.1016/j.ahj.2012.04.013.


Comparison of volume status in asymptomatic haemodialysis and peritoneal dialysis outpatients.

Papakrivopoulou E, Booth J, Pinney J, Davenport A.

Nephron Extra. 2012 Jan;2(1):48-54. doi: 10.1159/000337338. Epub 2012 Mar 26.



Pinney JH, Hawkins PN.

Ann Clin Biochem. 2012 May;49(Pt 3):229-41. doi: 10.1258/acb.2011.011225. Epub 2012 Mar 8. Review.


Cyclophosphamide, bortezomib, and dexamethasone therapy in AL amyloidosis is associated with high clonal response rates and prolonged progression-free survival.

Venner CP, Lane T, Foard D, Rannigan L, Gibbs SD, Pinney JH, Whelan CJ, Lachmann HJ, Gillmore JD, Hawkins PN, Wechalekar AD.

Blood. 2012 May 10;119(19):4387-90. doi: 10.1182/blood-2011-10-388462. Epub 2012 Feb 13.


Imaging longitudinal changes in articular cartilage and bone following doxycycline treatment in a rabbit anterior cruciate ligament transection model of osteoarthritis.

Pinney JR, Taylor C, Doan R, Burghardt AJ, Li X, Kim HT, Benjamin Ma C, Majumdar S.

Magn Reson Imaging. 2012 Feb;30(2):271-82. doi: 10.1016/j.mri.2011.09.025. Epub 2011 Nov 8.


Extravascular lung water predicts progression to acute lung injury in patients with increased risk*.

LeTourneau JL, Pinney J, Phillips CR.

Crit Care Med. 2012 Mar;40(3):847-54. doi: 10.1097/CCM.0b013e318236f60e.


Cardiac phenotype and clinical outcome of familial amyloid polyneuropathy associated with transthyretin alanine 60 variant.

Sattianayagam PT, Hahn AF, Whelan CJ, Gibbs SD, Pinney JH, Stangou AJ, Rowczenio D, Pflugfelder PW, Fox Z, Lachmann HJ, Wechalekar AD, Hawkins PN, Gillmore JD.

Eur Heart J. 2012 May;33(9):1120-7. doi: 10.1093/eurheartj/ehr383. Epub 2011 Oct 11.


Hereditary lysozyme amyloidosis -- phenotypic heterogeneity and the role of solid organ transplantation.

Sattianayagam PT, Gibbs SD, Rowczenio D, Pinney JH, Wechalekar AD, Gilbertson JA, Hawkins PN, Lachmann HJ, Gillmore JD.

J Intern Med. 2012 Jul;272(1):36-44. doi: 10.1111/j.1365-2796.2011.02470.x. Epub 2011 Nov 15.


Development of Microfabricated Magnetic Actuators for Removing Cellular Occlusion.

Lee SA, Lee H, Pinney JR, Khialeeva E, Bergsneider M, Judy JW.

J Micromech Microeng. 2011 May;21(5):54006.

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