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Items: 6

1.

Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N, Delano K, Da Silva I, Davis J, Gallo C, Gardner M, Golas AJ, Guinn KM, Kennedy S, Korn R, McConnell JA, Moss CE, Murphy KC, Nietupski RM, Papavinasasundaram KG, Pinkham JT, Pino PA, Proulx MK, Ruecker N, Song N, Thompson M, Trujillo C, Wakabayashi S, Wallach JB, Watson C, Ioerger TR, Lander ES, Hubbard BK, Serrano-Wu MH, Ehrt S, Fitzgerald M, Rubin EJ, Sassetti CM, Schnappinger D, Hung DT.

Nature. 2019 Jul;571(7763):72-78. doi: 10.1038/s41586-019-1315-z. Epub 2019 Jun 19.

PMID:
31217586
2.

Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.

Raju RM, Jedrychowski MP, Wei JR, Pinkham JT, Park AS, O'Brien K, Rehren G, Schnappinger D, Gygi SP, Rubin EJ.

PLoS Pathog. 2014 Mar 6;10(3):e1003994. doi: 10.1371/journal.ppat.1003994. eCollection 2014 Mar.

3.

Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance.

Javid B, Sorrentino F, Toosky M, Zheng W, Pinkham JT, Jain N, Pan M, Deighan P, Rubin EJ.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1132-7. doi: 10.1073/pnas.1317580111. Epub 2014 Jan 6.

4.

Genetic modification of the O-polysaccharide of Francisella tularensis results in an avirulent live attenuated vaccine.

Kim TH, Pinkham JT, Heninger SJ, Chalabaev S, Kasper DL.

J Infect Dis. 2012 Apr 1;205(7):1056-65. doi: 10.1093/infdis/jir620. Epub 2011 Oct 3.

5.

Characterization of the O-antigen polymerase (Wzy) of Francisella tularensis.

Kim TH, Sebastian S, Pinkham JT, Ross RA, Blalock LT, Kasper DL.

J Biol Chem. 2010 Sep 3;285(36):27839-49. doi: 10.1074/jbc.M110.143859. Epub 2010 Jul 6.

6.

Cellular and humoral immunity are synergistic in protection against types A and B Francisella tularensis.

Sebastian S, Pinkham JT, Lynch JG, Ross RA, Reinap B, Blalock LT, Conlan JW, Kasper DL.

Vaccine. 2009 Jan 22;27(4):597-605. doi: 10.1016/j.vaccine.2008.10.079. Epub 2008 Nov 18.

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