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Items: 45

1.

Heparan Sulfate Binding Coxsackievirus B3 Strain PD: A Novel Avirulent Oncolytic Agent Against Human Colorectal Carcinoma.

Hazini A, Pryshliak M, Brückner V, Klingel K, Sauter M, Pinkert S, Kurreck J, Fechner H.

Hum Gene Ther. 2018 Jun 20. doi: 10.1089/hum.2018.036. [Epub ahead of print]

PMID:
29739251
2.

The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.

Althof N, Goetzke CC, Kespohl M, Voss K, Heuser A, Pinkert S, Kaya Z, Klingel K, Beling A.

EMBO Mol Med. 2018 Feb;10(2):200-218. doi: 10.15252/emmm.201708089.

3.

The forkhead transcription factor Foxo3 negatively regulates natural killer cell function and viral clearance in myocarditis.

Loebel M, Holzhauser L, Hartwig JA, Shukla PC, Savvatis K, Jenke A, Gast M, Escher F, Becker SC, Bauer S, Stroux A, Beling A, Kespohl M, Pinkert S, Fechner H, Kuehl U, Lassner D, Poller W, Schultheiss HP, Zeller T, Blankenberg S, Papageorgiou AP, Heymans S, Landmesser U, Scheibenbogen C, Skurk C.

Eur Heart J. 2018 Mar 7;39(10):876-887. doi: 10.1093/eurheartj/ehx624.

PMID:
29136142
4.

Activation-induced cytidine deaminase prevents pro-B cell acute lymphoblastic leukemia by functioning as a negative regulator in Rag1 deficient pro-B cells.

Auer F, Ingenhag D, Pinkert S, Kracker S, Hacein-Bey-Abina S, Cavazzana M, Gombert M, Martin-Lorenzo A, Lin MH, Vicente-Dueñas C, Sánchez-García I, Borkhardt A, Hauer J.

Oncotarget. 2017 Sep 7;8(44):75797-75807. doi: 10.18632/oncotarget.20563. eCollection 2017 Sep 29.

5.

Infection of iPSC Lines with Miscarriage-Associated Coxsackievirus and Measles Virus and Teratogenic Rubella Virus as a Model for Viral Impairment of Early Human Embryogenesis.

Hübner D, Jahn K, Pinkert S, Böhnke J, Jung M, Fechner H, Rujescu D, Liebert UG, Claus C.

ACS Infect Dis. 2017 Dec 8;3(12):886-897. doi: 10.1021/acsinfecdis.7b00103. Epub 2017 Oct 26.

PMID:
29043768
6.

Anti-adenoviral Artificial MicroRNAs Expressed from AAV9 Vectors Inhibit Human Adenovirus Infection in Immunosuppressed Syrian Hamsters.

Schaar K, Geisler A, Kraus M, Pinkert S, Pryshliak M, Spencer JF, Tollefson AE, Ying B, Kurreck J, Wold WS, Klopfleisch R, Toth K, Fechner H.

Mol Ther Nucleic Acids. 2017 Sep 15;8:300-316. doi: 10.1016/j.omtn.2017.07.002. Epub 2017 Jul 8.

7.

NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis.

Tschöpe C, Müller I, Xia Y, Savvatis K, Pappritz K, Pinkert S, Lassner D, Heimesaat MM, Spillmann F, Miteva K, Bereswill S, Schultheiss HP, Fechner H, Pieske B, Kühl U, Van Linthout S.

Circ Heart Fail. 2017 Sep;10(9). pii: e003870. doi: 10.1161/CIRCHEARTFAILURE.117.003870.

PMID:
28912259
8.

First record of hawker dragonflies from Eocene Baltic amber (Odonata: Anisoptera: Gomphaeschnidae).

Pinkert S, Bechly G, Nel A.

Zootaxa. 2017 May 29;4272(2):263-275. doi: 10.11646/zootaxa.4272.2.7.

PMID:
28610295
9.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Walther DM, Kasturi P, Zheng M, Pinkert S, Vecchi G, Ciryam P, Morimoto RI, Dobson CM, Vendruscolo M, Mann M, Hartl FU.

Cell. 2017 Feb 23;168(5):944. doi: 10.1016/j.cell.2016.12.041. No abstract available.

10.

Soluble coxsackie- and adenovirus receptor (sCAR-Fc); a highly efficient compound against laboratory and clinical strains of coxsackie-B-virus.

Pinkert S, Dieringer B, Diedrich S, Zeichhardt H, Kurreck J, Fechner H.

Antiviral Res. 2016 Dec;136:1-8. doi: 10.1016/j.antiviral.2016.10.010. Epub 2016 Oct 20.

PMID:
27773751
11.

Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor.

Rühl G, Niedl AG, Patronov A, Siewert K, Pinkert S, Kalemanov M, Friese MA, Attfield KE, Antes I, Hohlfeld R, Dornmair K.

Neurol Neuroimmunol Neuroinflamm. 2016 May 17;3(4):e241. doi: 10.1212/NXI.0000000000000241. eCollection 2016 Aug.

12.

Biological antivirals for treatment of adenovirus infections.

Schaar K, Röger C, Pozzuto T, Kurreck J, Pinkert S, Fechner H.

Antivir Ther. 2016;21(7):559-566. doi: 10.3851/IMP3047. Epub 2016 Apr 1. Review.

PMID:
27032991
13.

The Coxsackievirus and Adenovirus Receptor: Glycosylation and the Extracellular D2 Domain Are Not Required for Coxsackievirus B3 Infection.

Pinkert S, Röger C, Kurreck J, Bergelson JM, Fechner H.

J Virol. 2016 May 27;90(12):5601-5610. doi: 10.1128/JVI.00315-16. Print 2016 Jun 15.

14.

Exome sequencing reveals a novel CWF19L1 mutation associated with intellectual disability and cerebellar atrophy.

Evers C, Kaufmann L, Seitz A, Paramasivam N, Granzow M, Karch S, Fischer C, Hinderhofer K, Gdynia G, Elsässer M, Pinkert S, Schlesner M, Bartram CR, Moog U.

Am J Med Genet A. 2016 Jun;170(6):1502-9. doi: 10.1002/ajmg.a.37632. Epub 2016 Mar 26.

PMID:
27016154
15.

Melanocyte antigen triggers autoimmunity in human psoriasis.

Arakawa A, Siewert K, Stöhr J, Besgen P, Kim SM, Rühl G, Nickel J, Vollmer S, Thomas P, Krebs S, Pinkert S, Spannagl M, Held K, Kammerbauer C, Besch R, Dornmair K, Prinz JC.

J Exp Med. 2015 Dec 14;212(13):2203-12. doi: 10.1084/jem.20151093. Epub 2015 Nov 30.

16.

Loss of function of PGAP1 as a cause of severe encephalopathy identified by Whole Exome Sequencing: Lessons of the bioinformatics pipeline.

Granzow M, Paramasivam N, Hinderhofer K, Fischer C, Chotewutmontri S, Kaufmann L, Evers C, Kotzaeridou U, Rohrschneider K, Schlesner M, Sturm M, Pinkert S, Eils R, Bartram CR, Bauer P, Moog U.

Mol Cell Probes. 2015 Oct;29(5):323-9. doi: 10.1016/j.mcp.2015.05.012. Epub 2015 Jun 4.

PMID:
26050939
17.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Walther DM, Kasturi P, Zheng M, Pinkert S, Vecchi G, Ciryam P, Morimoto RI, Dobson CM, Vendruscolo M, Mann M, Hartl FU.

Cell. 2015 May 7;161(4):919-32. doi: 10.1016/j.cell.2015.03.032. Erratum in: Cell. 2017 Feb 23;168(5):944.

18.

Expression of an engineered soluble coxsackievirus and adenovirus receptor by a dimeric AAV9 vector inhibits adenovirus infection in mice.

Röger C, Pozzuto T, Klopfleisch R, Kurreck J, Pinkert S, Fechner H.

Gene Ther. 2015 Jun;22(6):458-66. doi: 10.1038/gt.2015.19. Epub 2015 Mar 19.

PMID:
25786873
19.

Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome.

Ripaud L, Chumakova V, Antonin M, Hastie AR, Pinkert S, Körner R, Ruff KM, Pappu RV, Hornburg D, Mann M, Hartl FU, Hipp MS.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18219-24. doi: 10.1073/pnas.1421313111. Epub 2014 Dec 8.

20.

Formant frequencies and bandwidths of the vocal tract transfer function are affected by the mechanical impedance of the vocal tract wall.

Fleischer M, Pinkert S, Mattheus W, Mainka A, Mürbe D.

Biomech Model Mechanobiol. 2015 Aug;14(4):719-33. doi: 10.1007/s10237-014-0632-2. Epub 2014 Nov 23.

21.

Combination of RNA interference and virus receptor trap exerts additive antiviral activity in coxsackievirus B3-induced myocarditis in mice.

Stein EA, Pinkert S, Becher PM, Geisler A, Zeichhardt H, Klopfleisch R, Poller W, Tschöpe C, Lassner D, Fechner H, Kurreck J.

J Infect Dis. 2015 Feb 15;211(4):613-22. doi: 10.1093/infdis/jiu504. Epub 2014 Sep 5.

PMID:
25193982
22.

Proteomic analysis of the multimeric nuclear egress complex of human cytomegalovirus.

Milbradt J, Kraut A, Hutterer C, Sonntag E, Schmeiser C, Ferro M, Wagner S, Lenac T, Claus C, Pinkert S, Hamilton ST, Rawlinson WD, Sticht H, Couté Y, Marschall M.

Mol Cell Proteomics. 2014 Aug;13(8):2132-46. doi: 10.1074/mcp.M113.035782. Epub 2014 Jun 26.

23.

Interspecies differences in virus uptake versus cardiac function of the coxsackievirus and adenovirus receptor.

Freiberg F, Sauter M, Pinkert S, Govindarajan T, Kaldrack J, Thakkar M, Fechner H, Klingel K, Gotthardt M.

J Virol. 2014 Jul;88(13):7345-56. doi: 10.1128/JVI.00104-14. Epub 2014 Apr 16.

24.

Adiponectin promotes coxsackievirus B3 myocarditis by suppression of acute anti-viral immune responses.

Jenke A, Holzhauser L, Löbel M, Savvatis K, Wilk S, Weithäuser A, Pinkert S, Tschöpe C, Klingel K, Poller W, Scheibenbogen C, Schultheiss HP, Skurk C.

Basic Res Cardiol. 2014 May;109(3):408. doi: 10.1007/s00395-014-0408-y. Epub 2014 Apr 2.

PMID:
24691762
25.

A novel artificial microRNA expressing AAV vector for phospholamban silencing in cardiomyocytes improves Ca2+ uptake into the sarcoplasmic reticulum.

Gröβl T, Hammer E, Bien-Möller S, Geisler A, Pinkert S, Röger C, Poller W, Kurreck J, Völker U, Vetter R, Fechner H.

PLoS One. 2014 Mar 26;9(3):e92188. doi: 10.1371/journal.pone.0092188. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e107093.

26.

Interplay of acetyltransferase EP300 and the proteasome system in regulating heat shock transcription factor 1.

Raychaudhuri S, Loew C, Körner R, Pinkert S, Theis M, Hayer-Hartl M, Buchholz F, Hartl FU.

Cell. 2014 Feb 27;156(5):975-85. doi: 10.1016/j.cell.2014.01.055.

27.

Application of mutated miR-206 target sites enables skeletal muscle-specific silencing of transgene expression of cardiotropic AAV9 vectors.

Geisler A, Schön C, Größl T, Pinkert S, Stein EA, Kurreck J, Vetter R, Fechner H.

Mol Ther. 2013 May;21(5):924-33. doi: 10.1038/mt.2012.276. Epub 2013 Feb 26.

28.

Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response.

Sharma K, Vabulas RM, Macek B, Pinkert S, Cox J, Mann M, Hartl FU.

Mol Cell Proteomics. 2012 Mar;11(3):M111.014654. doi: 10.1074/mcp.M111.014654. Epub 2011 Dec 13.

29.

Pharmacological and biological antiviral therapeutics for cardiac coxsackievirus infections.

Fechner H, Pinkert S, Geisler A, Poller W, Kurreck J.

Molecules. 2011 Oct 11;16(10):8475-503. doi: 10.3390/molecules16108475. Review.

30.

Virus-host coevolution in a persistently coxsackievirus B3-infected cardiomyocyte cell line.

Pinkert S, Klingel K, Lindig V, Dörner A, Zeichhardt H, Spiller OB, Fechner H.

J Virol. 2011 Dec;85(24):13409-19. doi: 10.1128/JVI.00621-11. Epub 2011 Oct 5.

31.

Involvement of p32 and microtubules in alteration of mitochondrial functions by rubella virus.

Claus C, Chey S, Heinrich S, Reins M, Richardt B, Pinkert S, Fechner H, Gaunitz F, Schäfer I, Seibel P, Liebert UG.

J Virol. 2011 Apr;85(8):3881-92. doi: 10.1128/JVI.02492-10. Epub 2011 Jan 19.

32.

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions.

Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, Vendruscolo M, Hayer-Hartl M, Hartl FU, Vabulas RM.

Cell. 2011 Jan 7;144(1):67-78. doi: 10.1016/j.cell.2010.11.050.

33.

Inhibition of adenovirus infections by siRNA-mediated silencing of early and late adenoviral gene functions.

Eckstein A, Grössl T, Geisler A, Wang X, Pinkert S, Pozzuto T, Schwer C, Kurreck J, Weger S, Vetter R, Poller W, Fechner H.

Antiviral Res. 2010 Oct;88(1):86-94. doi: 10.1016/j.antiviral.2010.08.002. Epub 2010 Aug 11.

PMID:
20708037
34.

Versatility of trigger factor interactions with ribosome-nascent chain complexes.

Lakshmipathy SK, Gupta R, Pinkert S, Etchells SA, Hartl FU.

J Biol Chem. 2010 Sep 3;285(36):27911-23. doi: 10.1074/jbc.M110.134163. Epub 2010 Jul 1.

35.

Protein interaction networks--more than mere modules.

Pinkert S, Schultz J, Reichardt J.

PLoS Comput Biol. 2010 Jan 29;6(1):e1000659. doi: 10.1371/journal.pcbi.1000659.

36.

Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor.

Pinkert S, Westermann D, Wang X, Klingel K, Dörner A, Savvatis K, Grössl T, Krohn S, Tschöpe C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H.

Circulation. 2009 Dec 8;120(23):2358-66. doi: 10.1161/CIRCULATIONAHA.108.845339. Epub 2009 Nov 23.

37.

Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic antiviral activity against coxsackievirus B3.

Werk D, Pinkert S, Heim A, Zeichhardt H, Grunert HP, Poller W, Erdmann VA, Fechner H, Kurreck J.

Antiviral Res. 2009 Sep;83(3):298-306. doi: 10.1016/j.antiviral.2009.07.002. Epub 2009 Jul 8.

PMID:
19591879
38.

Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy.

Fechner H, Sipo I, Westermann D, Pinkert S, Wang X, Suckau L, Kurreck J, Zeichhardt H, Müller O, Vetter R, Erdmann V, Tschope C, Poller W.

J Mol Med (Berl). 2008 Sep;86(9):987-97. doi: 10.1007/s00109-008-0363-x. Epub 2008 Jun 12.

PMID:
18548221
39.

Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis.

Blenk S, Engelmann JC, Pinkert S, Weniger M, Schultz J, Rosenwald A, Müller-Hermelink HK, Müller T, Dandekar T.

BMC Cancer. 2008 Apr 16;8:106. doi: 10.1186/1471-2407-8-106.

40.

Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction.

Sipo I, Fechner H, Pinkert S, Suckau L, Wang X, Weger S, Poller W.

Gene Ther. 2007 Sep;14(18):1319-29. Epub 2007 Jul 5.

PMID:
17611587
41.

Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor.

Fechner H, Pinkert S, Wang X, Sipo I, Suckau L, Kurreck J, Dörner A, Sollerbrant K, Zeichhardt H, Grunert HP, Vetter R, Schultheiss HP, Poller W.

Gene Ther. 2007 Jun;14(12):960-71. Epub 2007 Mar 22.

PMID:
17377597
42.

A bidirectional Tet-dependent promotor construct regulating the expression of E1A for tight control of oncolytic adenovirus replication.

Fechner H, Wang X, Picó AH, Wildner J, Suckau L, Pinkert S, Sipo I, Weger S, Poller W.

J Biotechnol. 2007 Jan 20;127(4):560-74. Epub 2006 Sep 27.

PMID:
17083991
43.

Highly efficient and specific modulation of cardiac calcium homeostasis by adenovector-derived short hairpin RNA targeting phospholamban.

Fechner H, Suckau L, Kurreck J, Sipo I, Wang X, Pinkert S, Loschen S, Rekittke J, Weger S, Dekkers D, Vetter R, Erdmann VA, Schultheiss HP, Paul M, Lamers J, Poller W.

Gene Ther. 2007 Feb;14(3):211-8. Epub 2006 Oct 5.

PMID:
17024101
44.

Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets.

Gandhi TK, Zhong J, Mathivanan S, Karthick L, Chandrika KN, Mohan SS, Sharma S, Pinkert S, Nagaraju S, Periaswamy B, Mishra G, Nandakumar K, Shen B, Deshpande N, Nayak R, Sarker M, Boeke JD, Parmigiani G, Schultz J, Bader JS, Pandey A.

Nat Genet. 2006 Mar;38(3):285-93.

PMID:
16501559
45.

SMART 5: domains in the context of genomes and networks.

Letunic I, Copley RR, Pils B, Pinkert S, Schultz J, Bork P.

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D257-60.

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