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Items: 1 to 50 of 100

1.

Dynamic characteristics of the mitochondrial genome in SCNT pigs.

Yin T, Wang J, Xiang H, Pinkert CA, Li Q, Zhao X.

Biol Chem. 2019 Apr 24;400(5):613-623. doi: 10.1515/hsz-2018-0273.

PMID:
30367779
2.

A New Approach to Treating Neurodegenerative Otologic Disorders.

Moos WH, Faller DV, Glavas IP, Harpp DN, Irwin MH, Kanara I, Pinkert CA, Powers WR, Steliou K, Vavvas DG, Kodukula K.

Biores Open Access. 2018 Jul 1;7(1):107-115. doi: 10.1089/biores.2018.0017. eCollection 2018.

3.

Epigenetic Treatment of Neurodegenerative Ophthalmic Disorders: An Eye Toward the Future.

Moos WH, Faller DV, Glavas IP, Harpp DN, Irwin MH, Kanara I, Pinkert CA, Powers WR, Steliou K, Vavvas DG, Kodukula K.

Biores Open Access. 2017 Dec 1;6(1):169-181. doi: 10.1089/biores.2017.0036. eCollection 2017. Review.

4.

Epigenetic Treatment of Persistent Viral Infections.

Moos WH, Pinkert CA, Irwin MH, Faller DV, Kodukula K, Glavas IP, Steliou K.

Drug Dev Res. 2017 Feb;78(1):24-36. doi: 10.1002/ddr.21366. Epub 2016 Oct 20. Review.

PMID:
27761936
5.

Epigenetic Treatment of Neuropsychiatric Disorders: Autism and Schizophrenia.

Moos WH, Maneta E, Pinkert CA, Irwin MH, Hoffman ME, Faller DV, Steliou K.

Drug Dev Res. 2016 Mar;77(2):53-72. doi: 10.1002/ddr.21295. Epub 2016 Feb 21. Review.

PMID:
26899191
6.

Epigenetic Treatment of Neurodegenerative Disorders: Alzheimer and Parkinson Diseases.

Irwin MH, Moos WH, Faller DV, Steliou K, Pinkert CA.

Drug Dev Res. 2016 May;77(3):109-23. doi: 10.1002/ddr.21294. Epub 2016 Feb 21. Review.

PMID:
26899010
7.

Mitochondrial Haplotypes Influence Metabolic Traits in Porcine Transmitochondrial Cybrids.

Yu G, Xiang H, Tian J, Yin J, Pinkert CA, Li Q, Zhao X.

Sci Rep. 2015 Aug 19;5:13118. doi: 10.1038/srep13118.

8.

Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age.

Steliou K, Faller DV, Pinkert CA, Irwin MH, Moos WH.

Drug Dev Res. 2015 Jun;76(4):167-75. doi: 10.1002/ddr.21258.

PMID:
26109467
9.

Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition.

Parameshwaran K, Irwin MH, Steliou K, Suppiramaniam V, Pinkert CA.

Drug Dev Res. 2015 Mar;76(2):72-81. doi: 10.1002/ddr.21242. Epub 2015 Apr 3.

PMID:
25847731
10.

Mitochondrially-imported RNA in drug discovery.

Cannon MV, Irwin MH, Pinkert CA.

Drug Dev Res. 2015 Mar;76(2):61-71. doi: 10.1002/ddr.21241. Epub 2015 Apr 3.

PMID:
25847616
11.

Allotopic expression of ATP6 in the mouse as a transgenic model of mitochondrial disease.

Dunn DA, Pinkert CA.

Methods Mol Biol. 2015;1265:255-69. doi: 10.1007/978-1-4939-2288-8_18.

PMID:
25634280
12.

Effects of transgenic sterilization constructs and their repressor compounds on hatch, developmental rate and early survival of electroporated channel catfish embryos and fry.

Su B, Shang M, Li C, Perera DA, Pinkert CA, Irwin MH, Peatman E, Grewe P, Patil JG, Dunham RA.

Transgenic Res. 2015 Apr;24(2):333-52. doi: 10.1007/s11248-014-9846-4. Epub 2014 Nov 4.

PMID:
25367204
13.

Mitochondrial DNA sequence and phylogenetic evaluation of geographically disparate Sus scrofa breeds.

Cannon MV, Brandebourg TD, Kohn MC, Ðikić D, Irwin MH, Pinkert CA.

Anim Biotechnol. 2015;26(1):17-28. doi: 10.1080/10495398.2013.875474.

PMID:
25153451
14.

Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes.

Lee KK, Fujimoto K, Zhang C, Schwall CT, Alder NN, Pinkert CA, Krueger W, Rasmussen T, Boelsterli UA.

Free Radic Biol Med. 2013 Dec;65:584-594. doi: 10.1016/j.freeradbiomed.2013.07.038. Epub 2013 Jul 30.

PMID:
23911619
15.

Mouse models of mitochondrial complex I dysfunction.

Irwin MH, Parameshwaran K, Pinkert CA.

Int J Biochem Cell Biol. 2013 Jan;45(1):34-40. doi: 10.1016/j.biocel.2012.08.009. Epub 2012 Aug 10. Review.

16.

Nuclear expression of a mitochondrial DNA gene: mitochondrial targeting of allotopically expressed mutant ATP6 in transgenic mice.

Dunn DA, Pinkert CA.

J Biomed Biotechnol. 2012;2012:541245. doi: 10.1155/2012/541245. Epub 2012 Jun 20.

17.

Influence of intergeneric/interspecies mitochondrial injection; parthenogenetic development of bovine oocytes after injection of mitochondria derived from somatic cells.

Takeda K, Srirattana K, Matsukawa K, Akagi S, Kaneda M, Tasai M, Nirasawa K, Pinkert CA, Parnpai R, Nagai T.

J Reprod Dev. 2012;58(3):323-9. Epub 2012 Mar 9.

18.

Protection by an antioxidant of rotenone-induced neuromotor decline, reactive oxygen species generation and cellular stress in mouse brain.

Parameshwaran K, Irwin MH, Steliou K, Pinkert CA.

Pharmacol Biochem Behav. 2012 May;101(3):487-92. doi: 10.1016/j.pbb.2012.02.011. Epub 2012 Feb 17.

PMID:
22366220
19.

Comparative proteomic analysis of liver mitochondrial proteins derived from cloned adult pigs reconstructed with Meishan pig fibroblast cells and European pig enucleated oocytes.

Takeda K, Tasai M, Iwamoto M, Oe M, Chikuni K, Nakamura Y, Tagami T, Nirasawa K, Hanada H, Pinkert CA, Onishi A.

J Reprod Dev. 2012;58(2):248-53. Epub 2011 Dec 22.

20.

Animal models of human mitochondrial DNA mutations.

Dunn DA, Cannon MV, Irwin MH, Pinkert CA.

Biochim Biophys Acta. 2012 May;1820(5):601-7. doi: 10.1016/j.bbagen.2011.08.005. Epub 2011 Aug 11. Review.

21.

Mitochondrial biology in reproduction.

Cannon MV, Takeda K, Pinkert CA.

Reprod Med Biol. 2011 Aug 3;10(4):251-258. doi: 10.1007/s12522-011-0101-x. eCollection 2011 Dec. Review.

22.

Central insulin resistance and synaptic dysfunction in intracerebroventricular-streptozotocin injected rodents.

Shonesy BC, Thiruchelvam K, Parameshwaran K, Rahman EA, Karuppagounder SS, Huggins KW, Pinkert CA, Amin R, Dhanasekaran M, Suppiramaniam V.

Neurobiol Aging. 2012 Feb;33(2):430.e5-18. doi: 10.1016/j.neurobiolaging.2010.12.002. Epub 2011 Jan 21.

PMID:
21256630
23.

D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice.

Parameshwaran K, Irwin MH, Steliou K, Pinkert CA.

Rejuvenation Res. 2010 Dec;13(6):729-35. doi: 10.1089/rej.2010.1020. Epub 2011 Jan 4.

24.

Xenomitochondrial mice: investigation into mitochondrial compensatory mechanisms.

Cannon MV, Dunn DA, Irwin MH, Brooks AI, Bartol FF, Trounce IA, Pinkert CA.

Mitochondrion. 2011 Jan;11(1):33-9. doi: 10.1016/j.mito.2010.07.003. Epub 2010 Jul 16.

25.

Microinjection of serum-starved mitochondria derived from somatic cells affects parthenogenetic development of bovine and murine oocytes.

Takeda K, Tasai M, Akagi S, Matsukawa K, Takahashi S, Iwamoto M, Srirattana K, Onishi A, Tagami T, Nirasawa K, Hanada H, Pinkert CA.

Mitochondrion. 2010 Mar;10(2):137-42. doi: 10.1016/j.mito.2009.12.144. Epub 2009 Dec 11.

PMID:
20005304
26.

NDUFS4: creation of a mouse model mimicking a Complex I disorder.

Ingraham CA, Burwell LS, Skalska J, Brookes PS, Howell RL, Sheu SS, Pinkert CA.

Mitochondrion. 2009 Jun;9(3):204-10. doi: 10.1016/j.mito.2009.02.001. Epub 2009 Feb 11.

27.

In vivo cardioprotection by S-nitroso-2-mercaptopropionyl glycine.

Nadtochiy SM, Burwell LS, Ingraham CA, Spencer CM, Friedman AE, Pinkert CA, Brookes PS.

J Mol Cell Cardiol. 2009 Jun;46(6):960-8. doi: 10.1016/j.yjmcc.2009.01.012. Epub 2009 Feb 3.

28.

The mitochondrial genome sequence of Mus terricolor: comparison with Mus musculus domesticus and implications for xenomitochondrial mouse modeling.

Pogozelski WK, Fletcher LD, Cassar CA, Dunn DA, Trounce IA, Pinkert CA.

Gene. 2008 Jul 15;418(1-2):27-33. doi: 10.1016/j.gene.2008.04.001. Epub 2008 Apr 10.

29.

Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney.

Shen HM, Bozek G, Pinkert CA, McBride K, Wang L, Kenter A, Storb U.

Mol Immunol. 2008 Apr;45(7):1883-92. Epub 2007 Dec 11.

30.

Generation of transmitochondrial mice: development of xenomitochondrial mice to model neurodegenerative diseases.

Pinkert CA, Trounce IA.

Methods Cell Biol. 2007;80:549-69. Review. No abstract available.

PMID:
17445713
31.

Cybrid models of mtDNA disease and transmission, from cells to mice.

Trounce IA, Pinkert CA.

Curr Top Dev Biol. 2007;77:157-83. Review.

PMID:
17222703
32.

Muscle growth after postdevelopmental myostatin gene knockout.

Welle S, Bhatt K, Pinkert CA, Tawil R, Thornton CA.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E985-91. Epub 2006 Dec 5.

33.

Intraarticular induction of interleukin-1beta expression in the adult mouse, with resultant temporomandibular joint pathologic changes, dysfunction, and pain.

Lai YC, Shaftel SS, Miller JN, Tallents RH, Chang Y, Pinkert CA, Olschowka JA, Dickerson IM, Puzas JE, O'Banion MK, Kyrkanides S.

Arthritis Rheum. 2006 Apr;54(4):1184-97.

34.

Myofibrillar protein synthesis in myostatin-deficient mice.

Welle S, Bhatt K, Pinkert CA.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E409-15. Epub 2005 Oct 11.

35.

Developmental fate of mitochondria microinjected into murine zygotes.

Ingraham CA, Pinkert CA.

Mitochondrion. 2003 Aug;3(1):39-46.

PMID:
16120343
36.

Foundation Review: Transgenic animals and their impact on the drug discovery industry.

Dunn DA, Pinkert CA, Kooyman DL.

Drug Discov Today. 2005 Jun 1;10(11):757-67. Review.

PMID:
15922934
37.

Microinjection of cytoplasm or mitochondria derived from somatic cells affects parthenogenetic development of murine oocytes.

Takeda K, Tasai M, Iwamoto M, Onishi A, Tagami T, Nirasawa K, Hanada H, Pinkert CA.

Biol Reprod. 2005 Jun;72(6):1397-404. Epub 2005 Feb 16.

PMID:
15716395
38.

Development and initial characterization of xenomitochondrial mice.

Trounce IA, McKenzie M, Cassar CA, Ingraham CA, Lerner CA, Dunn DA, Donegan CL, Takeda K, Pogozelski WK, Howell RL, Pinkert CA.

J Bioenerg Biomembr. 2004 Aug;36(4):421-7.

PMID:
15377882
39.

Transgenic mouse with human mutant p53 expression in the prostate epithelium.

Elgavish A, Wood PA, Pinkert CA, Eltoum IE, Cartee T, Wilbanks J, Mentor-Marcel R, Tian L, Scroggins SE.

Prostate. 2004 Sep 15;61(1):26-34.

PMID:
15287091
40.
41.

Production of homoplasmic xenomitochondrial mice.

McKenzie M, Trounce IA, Cassar CA, Pinkert CA.

Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1685-90. Epub 2004 Jan 26.

42.

Mouse embryo yield and viability after euthanasia by CO2 inhalation or cervical dislocation.

Howell RL, Donegan CL, Pinkert CA.

Comp Med. 2003 Oct;53(5):510-3.

PMID:
14655993
43.

Transgenic animal technology: alternatives in genotyping and phenotyping.

Pinkert CA.

Comp Med. 2003 Apr;53(2):126-39. Review.

PMID:
12784846
44.

Functional respiratory chain analyses in murid xenomitochondrial cybrids expose coevolutionary constraints of cytochrome b and nuclear subunits of complex III.

McKenzie M, Chiotis M, Pinkert CA, Trounce IA.

Mol Biol Evol. 2003 Jul;20(7):1117-24. Epub 2003 May 30.

PMID:
12777531
45.

Mitochondrial activity in response to serum starvation in bovine (Bos taurus) cell culture.

Takeda K, Akagi S, Takahashi S, Onishi A, Hanada H, Pinkert CA.

Cloning Stem Cells. 2002;4(3):223-9.

PMID:
12398803
46.

Production of transmitochondrial mice.

Pinkert CA, Trounce IA.

Methods. 2002 Apr;26(4):348-57.

PMID:
12054926
47.

Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse.

Cox KB, Hamm DA, Millington DS, Matern D, Vockley J, Rinaldo P, Pinkert CA, Rhead WJ, Lindsey JR, Wood PA.

Hum Mol Genet. 2001 Sep 15;10(19):2069-77.

PMID:
11590124
48.

Membrane cofactor protein (MCP; CD46) expression in transgenic mice.

Kemper C, Leung M, Stephensen CB, Pinkert CA, Liszewski MK, Cattaneo R, Atkinson JP.

Clin Exp Immunol. 2001 May;124(2):180-9.

49.

Transgenic studies of fatty acid oxidation gene expression in nonobese diabetic mice.

Kurtz DM, Tian L, Gower BA, Nagy TR, Pinkert CA, Wood PA.

J Lipid Res. 2000 Dec;41(12):2063-70.

50.

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