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Items: 6


Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival.

Tang CH, Ranatunga S, Kriss CL, Cubitt CL, Tao J, Pinilla-Ibarz JA, Del Valle JR, Hu CC.

J Clin Invest. 2014 Jun;124(6):2585-98. doi: 10.1172/JCI73448. Epub 2014 May 8.


Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice.

Kriss CL, Pinilla-Ibarz JA, Mailloux AW, Powers JJ, Tang CH, Kang CW, Zanesi N, Epling-Burnette PK, Sotomayor EM, Croce CM, Del Valle JR, Hu CC.

Blood. 2012 Aug 2;120(5):1027-38. doi: 10.1182/blood-2011-11-394346. Epub 2012 Jun 12.


Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2'-deoxycytidine.

Dubovsky JA, Powers JJ, Gao Y, Mariusso LF, Sotomayor EM, Pinilla-Ibarz JA.

Leuk Res. 2011 Sep;35(9):1193-9. doi: 10.1016/j.leukres.2011.02.007. Epub 2011 Mar 5.


A molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors.

Powers JJ, Dubovsky JA, Epling-Burnette PK, Moscinski L, Zhang L, Mustjoki S, Sotomayor EM, Pinilla-Ibarz JA.

Leuk Lymphoma. 2011 Apr;52(4):668-79. doi: 10.3109/10428194.2010.550074. Epub 2011 Jan 27.


Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers.

Dubovsky JA, Wang D, Powers JJ, Berchmans E, Smith MA, Wright KL, Sotomayor EM, Pinilla-Ibarz JA.

Leuk Res. 2011 Mar;35(3):394-404. doi: 10.1016/j.leukres.2010.08.001. Epub 2010 Sep 22.


Treatment of chronic lymphocytic leukemia with a hypomethylating agent induces expression of NXF2, an immunogenic cancer testis antigen.

Dubovsky JA, McNeel DG, Powers JJ, Gordon J, Sotomayor EM, Pinilla-Ibarz JA.

Clin Cancer Res. 2009 May 15;15(10):3406-15. doi: 10.1158/1078-0432.CCR-08-2099. Epub 2009 Apr 28.

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