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Items: 30

1.

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.

Vanmeert M, Razzokov J, Mirza MU, Weeks SD, Schepers G, Bogaerts A, Rozenski J, Froeyen M, Herdewijn P, Pinheiro VB, Lescrinier E.

Nucleic Acids Res. 2019 Dec 16;47(22):11976-11977. doi: 10.1093/nar/gkz1090. No abstract available.

PMID:
31713624
2.

Correction: E. coli surface display of streptavidin for directed evolution of an allylic deallylase.

Heinisch T, Schwizer F, Garabedian B, Csibra E, Jeschek M, Vallapurackal J, Pinheiro VB, Marlière P, Panke S, Ward TR.

Chem Sci. 2019 Jun 28;10(27):6735. doi: 10.1039/c9sc90139f. eCollection 2019 Jul 21.

3.

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.

Vanmeert M, Razzokov J, Mirza MU, Weeks SD, Schepers G, Bogaerts A, Rozenski J, Froeyen M, Herdewijn P, Pinheiro VB, Lescrinier E.

Nucleic Acids Res. 2019 Jul 26;47(13):7130-7142. doi: 10.1093/nar/gkz551.

4.

Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli.

Fedorec AJH, Ozdemir T, Doshi A, Ho YK, Rosa L, Rutter J, Velazquez O, Pinheiro VB, Danino T, Barnes CP.

iScience. 2019 Apr 26;14:323-334. doi: 10.1016/j.isci.2019.03.019. Epub 2019 Mar 22.

5.

Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases.

Renders M, Dumbre S, Abramov M, Kestemont D, Margamuljana L, Largy E, Cozens C, Vandenameele J, Pinheiro VB, Toye D, Frère JM, Herdewijn P.

Nucleic Acids Res. 2019 Mar 18;47(5):2160-2168. doi: 10.1093/nar/gkz008.

6.

Engineering-driven biological insights into DNA polymerase mechanism.

Pinheiro VB.

Curr Opin Biotechnol. 2019 Dec;60:9-16. doi: 10.1016/j.copbio.2018.11.008. Epub 2018 Nov 28. Review.

PMID:
30502514
7.

E. coli surface display of streptavidin for directed evolution of an allylic deallylase.

Heinisch T, Schwizer F, Garabedian B, Csibra E, Jeschek M, Vallapurackal J, Pinheiro VB, Marlière P, Panke S, Ward TR.

Chem Sci. 2018 May 24;9(24):5383-5388. doi: 10.1039/c8sc00484f. eCollection 2018 Jun 28. Erratum in: Chem Sci. 2019 Jun 28;10(27):6735.

8.

XNA Synthesis and Reverse Transcription by Engineered Thermophilic Polymerases.

Cozens C, Pinheiro VB.

Curr Protoc Chem Biol. 2018 Sep;10(3):e47. doi: 10.1002/cpch.47. Epub 2018 Jul 24.

PMID:
30039931
9.

Xenobiotic Nucleic Acid (XNA) Synthesis by Phi29 DNA Polymerase.

Torres LL, Pinheiro VB.

Curr Protoc Chem Biol. 2018 Jun;10(2):e41. doi: 10.1002/cpch.41. Epub 2018 May 18.

PMID:
29927114
10.

Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo.

Jabgunde AM, Jaziri F, Bande O, Froeyen M, Abramov M, Nguyen H, Schepers G, Lescrinier E, Pinheiro VB, Pezo V, Marlière P, Herdewijn P.

Chemistry. 2018 Aug 27;24(48):12695-12707. doi: 10.1002/chem.201802304. Epub 2018 Jul 23.

PMID:
29883012
11.

XNA ligation using T4 DNA ligase in crowding conditions.

Kestemont D, Renders M, Leonczak P, Abramov M, Schepers G, Pinheiro VB, Rozenski J, Herdewijn P.

Chem Commun (Camb). 2018 Jun 14;54(49):6408-6411. doi: 10.1039/c8cc02414f.

PMID:
29872779
12.

Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers.

Liu C, Cozens C, Jaziri F, Rozenski J, Maréchal A, Dumbre S, Pezo V, Marlière P, Pinheiro VB, Groaz E, Herdewijn P.

J Am Chem Soc. 2018 May 30;140(21):6690-6699. doi: 10.1021/jacs.8b03447. Epub 2018 May 17.

PMID:
29722977
13.

Darwin Assembly: fast, efficient, multi-site bespoke mutagenesis.

Cozens C, Pinheiro VB.

Nucleic Acids Res. 2018 May 4;46(8):e51. doi: 10.1093/nar/gky067.

14.

Synthetic biology approaches to biological containment: pre-emptively tackling potential risks.

Torres L, Krüger A, Csibra E, Gianni E, Pinheiro VB.

Essays Biochem. 2016 Nov 30;60(4):393-410. Review.

15.

Selection platforms for directed evolution in synthetic biology.

Tizei PA, Csibra E, Torres L, Pinheiro VB.

Biochem Soc Trans. 2016 Aug 15;44(4):1165-75. doi: 10.1042/BST20160076. Review.

16.

Catalysing mirror life.

Renders M, Pinheiro VB.

Chembiochem. 2015 Apr 13;16(6):899-901. doi: 10.1002/cbic.201500010. Epub 2015 Mar 4.

PMID:
25739380
17.

Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo.

Bande O, Abu El Asrar R, Braddick D, Dumbre S, Pezo V, Schepers G, Pinheiro VB, Lescrinier E, Holliger P, Marlière P, Herdewijn P.

Chemistry. 2015 Mar 23;21(13):5009-22. doi: 10.1002/chem.201406392. Epub 2015 Feb 13.

18.

Catalysts from synthetic genetic polymers.

Taylor AI, Pinheiro VB, Smola MJ, Morgunov AS, Peak-Chew S, Cozens C, Weeks KM, Herdewijn P, Holliger P.

Nature. 2015 Feb 19;518(7539):427-30. doi: 10.1038/nature13982. Epub 2014 Dec 1.

19.

Compartmentalized Self-Tagging for In Vitro-Directed Evolution of XNA Polymerases.

Pinheiro VB, Arangundy-Franklin S, Holliger P.

Curr Protoc Nucleic Acid Chem. 2014 Jun 24;57:9.9.1-18. doi: 10.1002/0471142700.nc0909s57. Review.

PMID:
24961724
20.

Towards XNA nanotechnology: new materials from synthetic genetic polymers.

Pinheiro VB, Holliger P.

Trends Biotechnol. 2014 Jun;32(6):321-8. doi: 10.1016/j.tibtech.2014.03.010. Epub 2014 Apr 15. Review.

21.

Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA.

Wynne SA, Pinheiro VB, Holliger P, Leslie AG.

PLoS One. 2013 Aug 5;8(8):e70892. doi: 10.1371/journal.pone.0070892. Print 2013.

22.

The effect of sodium bicarbonate upon urinary citrate excretion in calcium stone formers.

Pinheiro VB, Baxmann AC, Tiselius HG, Heilberg IP.

Urology. 2013 Jul;82(1):33-7. doi: 10.1016/j.urology.2013.03.002. Epub 2013 Apr 18.

PMID:
23602798
23.

Synthetic polymers and their potential as genetic materials.

Pinheiro VB, Loakes D, Holliger P.

Bioessays. 2013 Feb;35(2):113-22. doi: 10.1002/bies.201200135. Epub 2012 Dec 27.

PMID:
23281109
24.

The XNA world: progress towards replication and evolution of synthetic genetic polymers.

Pinheiro VB, Holliger P.

Curr Opin Chem Biol. 2012 Aug;16(3-4):245-52. doi: 10.1016/j.cbpa.2012.05.198. Epub 2012 Jun 14. Review.

PMID:
22704981
25.

A short adaptive path from DNA to RNA polymerases.

Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8067-72. doi: 10.1073/pnas.1120964109. Epub 2012 May 7.

26.

Synthetic genetic polymers capable of heredity and evolution.

Pinheiro VB, Taylor AI, Cozens C, Abramov M, Renders M, Zhang S, Chaput JC, Wengel J, Peak-Chew SY, McLaughlin SH, Herdewijn P, Holliger P.

Science. 2012 Apr 20;336(6079):341-4. doi: 10.1126/science.1217622.

27.

Ice as a protocellular medium for RNA replication.

Attwater J, Wochner A, Pinheiro VB, Coulson A, Holliger P.

Nat Commun. 2010 Sep 21;1:76. doi: 10.1038/ncomms1076.

PMID:
20865803
28.

Evolving a polymerase for hydrophobic base analogues.

Loakes D, Gallego J, Pinheiro VB, Kool ET, Holliger P.

J Am Chem Soc. 2009 Oct 21;131(41):14827-37. doi: 10.1021/ja9039696.

29.

Expression and insecticidal activity of Yersinia pseudotuberculosis and Photorhabdus luminescens toxin complex proteins.

Pinheiro VB, Ellar DJ.

Cell Microbiol. 2007 Oct;9(10):2372-80. Epub 2007 Jun 15.

PMID:
17573906
30.

How to kill a mocking bug?

Pinheiro VB, Ellar DJ.

Cell Microbiol. 2006 Apr;8(4):545-57. Review.

PMID:
16548881

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