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Items: 1 to 50 of 205

1.

GUILDify v2.0: A Tool to Identify Molecular Networks Underlying Human Diseases, Their Comorbidities and Their Druggable Targets.

Aguirre-Plans J, Piñero J, Sanz F, Furlong LI, Fernandez-Fuentes N, Oliva B, Guney E.

J Mol Biol. 2019 Mar 7. pii: S0022-2836(19)30117-2. doi: 10.1016/j.jmb.2019.02.027. [Epub ahead of print]

PMID:
30851278
2.

Room Temperature Methane Capture and Activation by Ni Clusters Supported on TiC(001): Effects of Metal-Carbide Interactions on the Cleavage of the C-H Bond.

Prats H, Gutiérrez RA, Piñero JJ, Viñes F, Bromley ST, Ramírez PJ, Rodriguez JA, Illas F.

J Am Chem Soc. 2019 Mar 18. doi: 10.1021/jacs.8b13552. [Epub ahead of print]

PMID:
30848129
3.

Publisher Correction: Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set.

IMEx Consortium contributing authors, Del-Toro N, Duesbury M, Koch M, Perfetto L, Shrivastava A, Ochoa D, Wagih O, Piñero J, Kotlyar M, Pastrello C, Beltrao P, Furlong LI, Jurisica I, Hermjakob H, Orchard S, Porras P.

Nat Commun. 2019 Mar 4;10(1):1098. doi: 10.1038/s41467-019-08814-w.

4.

Isolation and molecular identification of free-living amoebae from dishcloths in Tenerife, Canary Islands, Spain.

Reyes-Batlle M, Hernández-Piñero I, Rizo-Liendo A, López-Arencibia A, Sifaoui I, Bethencourt-Estrella CJ, Chiboub O, Valladares B, Piñero JE, Lorenzo-Morales J.

Parasitol Res. 2019 Mar;118(3):927-933. doi: 10.1007/s00436-018-06193-7. Epub 2019 Feb 1.

PMID:
30707288
5.

Evaluation of the sensitivity to chlorhexidine, voriconazole and itraconazole of T4 genotype Acanthamoeba isolated from Mexico.

Hernández-Martínez D, Reyes-Batlle M, Castelan-Ramírez I, Hernández-Olmos P, Vanzzini-Zago V, Ramírez-Flores E, Sifaoui I, Piñero JE, Lorenzo-Morales J, Omaña-Molina M.

Exp Parasitol. 2019 Feb;197:29-35. doi: 10.1016/j.exppara.2019.01.006. Epub 2019 Jan 12.

PMID:
30648558
6.

Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set.

IMEx Consortium Curators, Del-Toro N, Duesbury M, Koch M, Perfetto L, Shrivastava A, Ochoa D, Wagih O, Piñero J, Kotlyar M, Pastrello C, Beltrao P, Furlong LI, Jurisica I, Hermjakob H, Orchard S, Porras P.

Nat Commun. 2019 Jan 2;10(1):10. doi: 10.1038/s41467-018-07709-6. Erratum in: Nat Commun. 2019 Mar 4;10(1):1098.

7.

Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury.

Souza T, Trairatphisan P, Piñero J, Furlong LI, Saez-Rodriguez J, Kleinjans J, Jennen D.

Front Genet. 2018 Nov 20;9:527. doi: 10.3389/fgene.2018.00527. eCollection 2018.

8.

Anti-Acanthamoeba Activity of Brominated Sesquiterpenes from Laurencia johnstonii.

García-Davis S, Sifaoui I, Reyes-Batlle M, Viveros-Valdez E, Piñero JE, Lorenzo-Morales J, Fernández JJ, Díaz-Marrero AR.

Mar Drugs. 2018 Nov 11;16(11). pii: E443. doi: 10.3390/md16110443.

9.

Network, Transcriptomic and Genomic Features Differentiate Genes Relevant for Drug Response.

Piñero J, Gonzalez-Perez A, Guney E, Aguirre-Plans J, Sanz F, Oliva B, Furlong LI.

Front Genet. 2018 Sep 25;9:412. doi: 10.3389/fgene.2018.00412. eCollection 2018.

10.

A Solvothermal Synthesis of TiO₂ Nanoparticles in a Non-Polar Medium to Prepare Highly Stable Nanofluids with Improved Thermal Properties.

Aguilar T, Carrillo-Berdugo I, Gómez-Villarejo R, Gallardo JJ, Martínez-Merino P, Piñero JC, Alcántara R, Fernández-Lorenzo C, Navas J.

Nanomaterials (Basel). 2018 Oct 10;8(10). pii: E816. doi: 10.3390/nano8100816.

11.

Pancreatic cancer and autoimmune diseases: An association sustained by computational and epidemiological case-control approaches.

Gomez-Rubio P, Piñero J, Molina-Montes E, Gutiérrez-Sacristán A, Marquez M, Rava M, Michalski CW, Farré A, Molero X, Löhr M, Perea J, Greenhalf W, O'Rorke M, Tardón A, Gress T, Barberá VM, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Domínguez-Muñoz E, Balsells J, Costello E, Yu J, Iglesias M, Ilzarbe L, Kleeff J, Kong B, Mora J, Murray L, O'Driscoll D, Poves I, Lawlor RT, Ye W, Hidalgo M, Scarpa A, Sharp L, Carrato A, Real FX, Furlong LI, Malats N; PanGenEU Study Investigators.

Int J Cancer. 2019 Apr 1;144(7):1540-1549. doi: 10.1002/ijc.31866. Epub 2018 Oct 26.

PMID:
30229903
12.

In silico models in drug development: where we are.

Piñero J, Furlong LI, Sanz F.

Curr Opin Pharmacol. 2018 Oct;42:111-121. doi: 10.1016/j.coph.2018.08.007. Epub 2018 Sep 8. Review.

PMID:
30205360
13.

Leishmanicidal activity of α-bisabolol from Tunisian chamomile essential oil.

Hajaji S, Sifaoui I, López-Arencibia A, Reyes-Batlle M, Jiménez IA, Bazzocchi IL, Valladares B, Akkari H, Lorenzo-Morales J, Piñero JE.

Parasitol Res. 2018 Sep;117(9):2855-2867. doi: 10.1007/s00436-018-5975-7. Epub 2018 Jun 28.

PMID:
29955971
14.

Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology.

Aguirre-Plans J, Piñero J, Menche J, Sanz F, Furlong LI, Schmidt HHHW, Oliva B, Guney E.

Pharmaceuticals (Basel). 2018 Jun 22;11(3). pii: E61. doi: 10.3390/ph11030061.

15.

Toxic effects of selected proprietary dry eye drops on Acanthamoeba.

Sifaoui I, Reyes-Batlle M, López-Arencibia A, Chiboub O, Rodríguez-Martín J, Rocha-Cabrera P, Valladares B, Piñero JE, Lorenzo-Morales J.

Sci Rep. 2018 Jun 4;8(1):8520. doi: 10.1038/s41598-018-26914-3.

16.

Effect of Physiological State on Female Melon Fly (Diptera: Tephritidae) Attraction to Host and Food Odor in the Field.

Vargas RI, Piñero JC, Miller NW.

J Econ Entomol. 2018 May 28;111(3):1318-1322. doi: 10.1093/jee/toy092.

PMID:
29659892
17.

Presence of Acanthamoeba in the ocular surface in a Spanish population of contact lens wearers.

Rodríguez-Martín J, Rocha-Cabrera P, Reyes-Batlle M, López-Arencibia A, Sifaoui I, Rizo-Liendo A, Bethencourt-Estrella CJ, Piñero JE, Lorenzo-Morales J.

Acta Parasitol. 2018 Jun 26;63(2):393-396. doi: 10.1515/ap-2018-0045.

PMID:
29654681
19.

Detection and molecular characterization of Acanthamoeba spp. in stray cats from Madrid, Spain.

Montoya A, Miró G, Saugar JM, Fernández B, Checa R, Gálvez R, Bailo B, Marino V, Piñero JE, Lorenzo-Morales J, Fuentes I.

Exp Parasitol. 2018 May;188:8-12. doi: 10.1016/j.exppara.2018.02.011. Epub 2018 Mar 1.

PMID:
29501695
20.

Mass trapping designs for organic control of the Japanese beetle, Popillia japonica (Coleoptera: Scarabaeidae).

Piñero JC, Dudenhoeffer AP.

Pest Manag Sci. 2018 Jul;74(7):1687-1693. doi: 10.1002/ps.4862. Epub 2018 Mar 6.

PMID:
29337404
21.

Assessment of the antiprotozoal activity of Pulicaria inuloides extracts, an Algerian medicinal plant: leishmanicidal bioguided fractionation.

Fadel H, Sifaoui I, López-Arencibia A, Reyes-Batlle M, Hajaji S, Chiboub O, Jiménez IA, Bazzocchi IL, Lorenzo-Morales J, Benayache S, Piñero JE.

Parasitol Res. 2018 Feb;117(2):531-537. doi: 10.1007/s00436-017-5731-4. Epub 2018 Jan 6.

PMID:
29306999
22.

Selective activity of Oleanolic and Maslinic Acids on the Amastigote form of Leishmania Spp.

Sifaoui I, López-Arencibia A, Martín-Navarro CM, Reyes-Batlle M, Mejri M, Valladares B, Lorenzo-Morales J, Abderabba M, Piñero JE.

Iran J Pharm Res. 2017 Summer;16(3):1190-1193.

23.

The architecture of mutualistic networks as an evolutionary spandrel.

Valverde S, Piñero J, Corominas-Murtra B, Montoya J, Joppa L, Solé R.

Nat Ecol Evol. 2018 Jan;2(1):94-99. doi: 10.1038/s41559-017-0383-4. Epub 2017 Nov 20.

24.

Design, synthesis and evaluation of amino-substituted 1H-phenalen-1-ones as anti-leishmanial agents.

Freijo MB, López-Arencibia A, Piñero JE, McNaughton-Smith G, Abad-Grillo T.

Eur J Med Chem. 2018 Jan 1;143:1312-1324. doi: 10.1016/j.ejmech.2017.10.032. Epub 2017 Oct 14.

PMID:
29126735
25.

Chemical composition and anti-Acanthamoeba activity of Melaleuca styphelioides essential oil.

Albouchi F, Sifaoui I, Reyes-Batlle M, López-Arencibia A, Piñero JE, Lorenzo-Morales J, Abderrabba M.

Exp Parasitol. 2017 Dec;183:104-108. doi: 10.1016/j.exppara.2017.10.014. Epub 2017 Nov 10.

PMID:
29103900
26.

In vitro amoebicidal and antioxidant activities of some Tunisian seaweeds.

Chiboub O, Ktari L, Sifaoui I, López-Arencibia A, Reyes-Batlle M, Mejri M, Valladares B, Abderrabba M, Piñero JE, Lorenzo-Morales J.

Exp Parasitol. 2017 Dec;183:76-80. doi: 10.1016/j.exppara.2017.10.012. Epub 2017 Nov 2.

PMID:
29102681
27.

Ammoides pusilla (Apiaceae) essential oil: Activity against Acanthamoeba castellanii Neff.

Souhaiel N, Sifaoui I, Ben Hassine D, Bleton J, Bonose M, Moussa F, Piñero JE, Lorenzo-Morales J, Abderrabba M.

Exp Parasitol. 2017 Dec;183:99-103. doi: 10.1016/j.exppara.2017.10.011. Epub 2017 Nov 2.

PMID:
29102680
28.

Correlation of radical-scavenging capacity and amoebicidal activity of Matricaria recutita L. (Asteraceae).

Hajaji S, Sifaoui I, López-Arencibia A, Reyes-Batlle M, Jiménez IA, Bazzocchi IL, Valladares B, Pinero JE, Lorenzo-Morales J, Akkari H.

Exp Parasitol. 2017 Dec;183:212-217. doi: 10.1016/j.exppara.2017.09.011. Epub 2017 Sep 14.

PMID:
28919332
29.

In vitro interactions of Acanthamoeba castellanii Neff and Vibrio harveyi.

Reyes-Batlle M, Martín-Rodríguez AJ, López-Arencibia A, Sifaoui I, Liendo AR, Bethencourt Estrella CJ, García Méndez AB, Chiboub O, Hajaji S, Valladares B, Martínez-Carretero E, Piñero JE, Lorenzo-Morales J.

Exp Parasitol. 2017 Dec;183:167-170. doi: 10.1016/j.exppara.2017.09.003. Epub 2017 Sep 13.

PMID:
28917709
30.

Amoebicidal, antimicrobial and in vitro ROS scavenging activities of Tunisian Rubus ulmifolius Schott, methanolic extract.

Hajaji S, Jabri MA, Sifaoui I, López-Arencibia A, Reyes-Batlle M, B'chir F, Valladares B, Pinero JE, Lorenzo-Morales J, Akkari H.

Exp Parasitol. 2017 Dec;183:224-230. doi: 10.1016/j.exppara.2017.09.013. Epub 2017 Sep 13.

PMID:
28917707
31.

Variation in Campylobacter jejuni culturability in presence of Acanthamoeba castellanii Neff.

Reyes-Batlle M, Girbau C, López-Arencibia A, Sifaoui I, Liendo AR, Bethencourt Estrella CJ, García Méndez AB, Chiboub O, Hajaji S, Fernández-Astorga A, Valladares B, Martínez-Carretero E, Piñero JE, Lorenzo-Morales J.

Exp Parasitol. 2017 Dec;183:178-181. doi: 10.1016/j.exppara.2017.09.005. Epub 2017 Sep 12.

PMID:
28916459
32.

In vitro activity of 1H-phenalen-1-one derivatives against Acanthamoeba castellanii Neff and their mechanisms of cell death.

López-Arencibia A, Reyes-Batlle M, Freijo MB, McNaughton-Smith G, Martín-Rodríguez P, Fernández-Pérez L, Sifaoui I, Wagner C, García-Méndez AB, Liendo AR, Bethencourt-Estrella CJ, Abad-Grillo T, Piñero JE, Lorenzo-Morales J.

Exp Parasitol. 2017 Dec;183:218-223. doi: 10.1016/j.exppara.2017.09.012. Epub 2017 Sep 13.

PMID:
28916457
33.

Anti-Acanthamoeba activity of Tunisian Thymus capitatus essential oil and organic extracts.

Saoudi S, Sifaoui I, Chammem N, Reyes-Batlle M, López-Arencibia A, Pacheco-Fernández I, Pino V, Hamdi M, Jiménez IA, Bazzocchi IL, Piñero JE, Lorenzo-Morales J.

Exp Parasitol. 2017 Dec;183:231-235. doi: 10.1016/j.exppara.2017.09.014. Epub 2017 Sep 12.

PMID:
28916454
34.

Programmed cell death in Acanthamoeba castellanii Neff induced by several molecules present in olive leaf extracts.

Sifaoui I, López-Arencibia A, Martín-Navarro CM, Reyes-Batlle M, Wagner C, Chiboub O, Mejri M, Valladares B, Abderrabba M, Piñero JE, Lorenzo-Morales J.

PLoS One. 2017 Aug 31;12(8):e0183795. doi: 10.1371/journal.pone.0183795. eCollection 2017.

35.

Structure elucidation, total assignment of the 1 H and 13 C chemical shifts, and absolute configuration by NMR techniques of dammarane-type triterpenes from Hippocratea volubilis.

Kennedy ML, López-Arencibia A, Reyes-Batlle M, Lorenzo-Morales J, Piñero JE, Bazzocchi IL, Jiménez IA.

Magn Reson Chem. 2018 Jan;56(1):46-54. doi: 10.1002/mrc.4644. Epub 2017 Sep 14. No abstract available.

PMID:
28806857
36.

Evaluation of the anti-Acanthamoeba activity of two commercial eye drops commonly used to lower eye pressure.

Sifaoui I, Reyes-Batlle M, López-Arencibia A, Wagner C, Chiboub O, De Agustino Rodríguez J, Rocha-Cabrera P, Valladares B, Piñero JE, Lorenzo-Morales J.

Exp Parasitol. 2017 Dec;183:117-123. doi: 10.1016/j.exppara.2017.07.012. Epub 2017 Aug 1.

PMID:
28778743
37.

Genetic and functional characterization of disease associations explains comorbidity.

Rubio-Perez C, Guney E, Aguilar D, Piñero J, Garcia-Garcia J, Iadarola B, Sanz F, Fernandez-Fuentes N, Furlong LI, Oliva B.

Sci Rep. 2017 Jul 24;7(1):6207. doi: 10.1038/s41598-017-04939-4.

38.

Specific humoral and cellular immune responses in cancer patients undergoing chronic immunization with a VEGF-based therapeutic vaccine.

Morera Y, Sánchez J, Bequet-Romero M, Selman-Housein KH, de la Torre A, Hernández-Bernal F, Martín Y, Garabito A, Piñero J, Bermúdez C, de la Torre J, Ayala M, Gavilondo JV.

Vaccine. 2017 Jun 16;35(28):3582-3590. doi: 10.1016/j.vaccine.2017.05.020. Epub 2017 May 20.

PMID:
28536029
39.

Amoebicidal activity of α-bisabolol, the main sesquiterpene in chamomile (Matricaria recutita L.) essential oil against the trophozoite stage of Acanthamoeba castellani Neff.

Hajaji S, Sifaoui I, López-Arencibia A, Reyes-Batlle M, Valladares B, Pinero JE, Lorenzo-Morales J, Akkari H.

Acta Parasitol. 2017 Jun 1;62(2):290-295. doi: 10.1515/ap-2017-0036.

PMID:
28426414
40.

Isolation and molecular characterization of a Naegleria strain from a recreational water fountain in Tenerife, Canary Islands, Spain.

Reyes-Batlle M, Wagner C, López-Arencibia A, Sifaoui I, Martínez-Carretero E, Valladares B, Piñero JE, Lorenzo-Morales J.

Acta Parasitol. 2017 Jun 1;62(2):265-268. doi: 10.1515/ap-2017-0033.

PMID:
28426408
41.

A systems approach identifies time-dependent associations of multimorbidities with pancreatic cancer risk.

Gomez-Rubio P, Rosato V, Márquez M, Bosetti C, Molina-Montes E, Rava M, Piñero J, Michalski CW, Farré A, Molero X, Löhr M, Ilzarbe L, Perea J, Greenhalf W, O'Rorke M, Tardón A, Gress T, Barberá VM, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Domínguez-Muñoz E, Gutiérrez-Sacristán A, Balsells J, Costello E, Guillén-Ponce C, Huang J, Iglesias M, Kleeff J, Kong B, Mora J, Murray L, O'Driscoll D, Peláez P, Poves I, Lawlor RT, Carrato A, Hidalgo M, Scarpa A, Sharp L, Furlong LI, Real FX, La Vecchia C, Malats N; PanGenEU Study Investigators.

Ann Oncol. 2017 Jul 1;28(7):1618-1624. doi: 10.1093/annonc/mdx167.

PMID:
28383714
42.

Vision-mediated exploitation of a novel host plant by a tephritid fruit fly.

Piñero JC, Souder SK, Vargas RI.

PLoS One. 2017 Apr 5;12(4):e0174636. doi: 10.1371/journal.pone.0174636. eCollection 2017.

43.

Amoebicidal Activity of Caffeine and Maslinic Acid by the Induction of Programmed Cell Death in Acanthamoeba.

Martín-Navarro CM, López-Arencibia A, Sifaoui I, Reyes-Batlle M, Fouque E, Osuna A, Valladares B, Piñero JE, Héchard Y, Maciver SK, Lorenzo-Morales J.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02660-16. doi: 10.1128/AAC.02660-16. Print 2017 Jun.

44.

Perifosine Mechanisms of Action in Leishmania Species.

López-Arencibia A, Martín-Navarro C, Sifaoui I, Reyes-Batlle M, Wagner C, Lorenzo-Morales J, Maciver SK, Piñero JE.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02127-16. doi: 10.1128/AAC.02127-16. Print 2017 Apr.

45.

Combined effect of carnosol, rosmarinic acid and thymol on the oxidative stability of soybean oil using a simplex centroid mixture design.

Saoudi S, Chammem N, Sifaoui I, Jiménez IA, Lorenzo-Morales J, Piñero JE, Bouassida-Beji M, Hamdi M, L Bazzocchi I.

J Sci Food Agric. 2017 Aug;97(10):3300-3311. doi: 10.1002/jsfa.8179. Epub 2017 Jan 13.

PMID:
27976408
46.

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants.

Piñero J, Bravo À, Queralt-Rosinach N, Gutiérrez-Sacristán A, Deu-Pons J, Centeno E, García-García J, Sanz F, Furlong LI.

Nucleic Acids Res. 2017 Jan 4;45(D1):D833-D839. doi: 10.1093/nar/gkw943. Epub 2016 Oct 19.

47.

Genotyping of clinical isolates of Acanthamoeba genus in Venezuela.

Wagner C, Reyes-Batlle M, Ysea MA, Pérez MV, de Rondón CG, Paduani AJ, Pérez AD, López-Arencibia A, Sifaoui I, de Galindo MV, de Suárez EP, Martínez-Carretero E, Valladares B, Piñero JE, Lorenzo-Morales J.

Acta Parasitol. 2016 Dec 1;61(4):796-801. doi: 10.1515/ap-2016-0110.

PMID:
27787218
48.

Isolation of thermotolerant Vermamoeba vermiformis strains from water sources in Lanzarote Island, Canary Islands, Spain.

Reyes-Batlle M, Wagner C, Zamora-Herrera J, Vargas-Mesa A, Sifaoui I, González AC, López-Arencibia A, Valladares B, Martínez-Carretero E, Piñero JE, Lorenzo-Morales J.

Acta Parasitol. 2016 Sep 1;61(3):650-3. doi: 10.1515/ap-2016-0088.

PMID:
27447234
49.

High occurrence of Acanthamoeba genotype T4 in soil sources from Bolívar State, Venezuela.

Wagner C, Reyes-Batlle M, Hernán A, Rojas E, Pérez G, López-Arencibia A, Sifaoui I, Martínez-Carretero E, Piñero JE, Valladares B, Lorenzo-Morales J.

Acta Parasitol. 2016 Sep 1;61(3):466-70. doi: 10.1515/ap-2016-0063.

PMID:
27447209
50.

DisGeNET-RDF: harnessing the innovative power of the Semantic Web to explore the genetic basis of diseases.

Queralt-Rosinach N, Piñero J, Bravo À, Sanz F, Furlong LI.

Bioinformatics. 2016 Jul 15;32(14):2236-8. doi: 10.1093/bioinformatics/btw214. Epub 2016 Apr 22.

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