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Items: 45


pathCHEMO, a generalizable computational framework uncovers molecular pathways of chemoresistance in lung adenocarcinoma.

Epsi NJ, Panja S, Pine SR, Mitrofanova A.

Commun Biol. 2019 Sep 6;2:334. doi: 10.1038/s42003-019-0572-6. eCollection 2019.


Relationship between West African ancestry with lung cancer risk and survival in African Americans.

Mitchell KA, Shah E, Bowman ED, Zingone A, Nichols N, Pine SR, Kittles RA, Ryan BM.

Cancer Causes Control. 2019 Nov;30(11):1259-1268. doi: 10.1007/s10552-019-01212-z. Epub 2019 Aug 29.


A Novel Acquired Exon 20 EGFR M766Q Mutation in Lung Adenocarcinoma Mediates Osimertinib Resistance but is Sensitive to Neratinib and Poziotinib.

Castellano GM, Aisner J, Burley SK, Vallat B, Yu HA, Pine SR, Ganesan S.

J Thorac Oncol. 2019 Jun 27. pii: S1556-0864(19)30495-2. doi: 10.1016/j.jtho.2019.06.015. [Epub ahead of print]


Circulating Inflammation Proteins Associated With Lung Cancer in African Americans.

Meaney CL, Mitchell KA, Zingone A, Brown D, Bowman E, Yu Y, Wenzlaff AS, Neslund-Dudas C, Pine SR, Cao L, Schwartz AG, Ryan BM.

J Thorac Oncol. 2019 Jul;14(7):1192-1203. doi: 10.1016/j.jtho.2019.03.014. Epub 2019 Apr 3.


Identifying therapeutic vulnerabilities in lung cancer: application of a chemistry-first approach.

Pine SR, Ryan BM.

Transl Lung Cancer Res. 2018 Sep;7(Suppl 3):S265-S269. doi: 10.21037/tlcr.2018.09.10. No abstract available.


Editorial: Harnessing the Power of Patient Derived Models of Cancer.

Pine SR, Sabaawy HE.

Front Oncol. 2018 Sep 6;8:349. doi: 10.3389/fonc.2018.00349. eCollection 2018. No abstract available.


Rethinking Gamma-secretase Inhibitors for Treatment of Non-small-Cell Lung Cancer: Is Notch the Target?

Pine SR.

Clin Cancer Res. 2018 Dec 15;24(24):6136-6141. doi: 10.1158/1078-0432.CCR-18-1635. Epub 2018 Aug 13.


Utility of Glioblastoma Patient-Derived Orthotopic Xenografts in Drug Discovery and Personalized Therapy.

Patrizii M, Bartucci M, Pine SR, Sabaawy HE.

Front Oncol. 2018 Feb 12;8:23. doi: 10.3389/fonc.2018.00023. eCollection 2018.


Gamma Secretase Inhibition by BMS-906024 Enhances Efficacy of Paclitaxel in Lung Adenocarcinoma.

Morgan KM, Fischer BS, Lee FY, Shah JJ, Bertino JR, Rosenfeld J, Singh A, Khiabanian H, Pine SR.

Mol Cancer Ther. 2017 Dec;16(12):2759-2769. doi: 10.1158/1535-7163.MCT-17-0439. Epub 2017 Oct 4.


Patient-Derived Xenograft Models of Non-Small Cell Lung Cancer and Their Potential Utility in Personalized Medicine.

Morgan KM, Riedlinger GM, Rosenfeld J, Ganesan S, Pine SR.

Front Oncol. 2017 Jan 19;7:2. doi: 10.3389/fonc.2017.00002. eCollection 2017.


SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.

Hong X, Liu W, Song R, Shah JJ, Feng X, Tsang CK, Morgan KM, Bunting SF, Inuzuka H, Zheng XF, Shen Z, Sabaawy HE, Liu L, Pine SR.

Nucleic Acids Res. 2016 Oct 14;44(18):8855-8869. Epub 2016 Aug 26.


Differential Serum Cytokine Levels and Risk of Lung Cancer Between African and European Americans.

Pine SR, Mechanic LE, Enewold L, Bowman ED, Ryan BM, Cote ML, Wenzlaff AS, Loffredo CA, Olivo-Marston S, Chaturvedi A, Caporaso NE, Schwartz AG, Harris CC.

Cancer Epidemiol Biomarkers Prev. 2016 Mar;25(3):488-97. doi: 10.1158/1055-9965.EPI-15-0378. Epub 2015 Dec 28.


Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer.

Ryan BM, Robles AI, McClary AC, Haznadar M, Bowman ED, Pine SR, Brown D, Khan M, Shiraishi K, Kohno T, Okayama H, Modali R, Yokota J, Harris CC.

Cancer Res. 2015 Feb 1;75(3):566-75. doi: 10.1158/0008-5472.CAN-14-2101. Epub 2014 Dec 5.


Asymmetric cell division and template DNA co-segregation in cancer stem cells.

Pine SR, Liu W.

Front Oncol. 2014 Aug 21;4:226. doi: 10.3389/fonc.2014.00226. eCollection 2014. Review.


A combined prognostic serum interleukin-8 and interleukin-6 classifier for stage 1 lung cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.

Ryan BM, Pine SR, Chaturvedi AK, Caporaso N, Harris CC.

J Thorac Oncol. 2014 Oct;9(10):1494-503. doi: 10.1097/JTO.0000000000000278.


Activation of the Notch1 Stem Cell Signaling Pathway during Routine Cell Line Subculture.

Liu W, Morgan KM, Pine SR.

Front Oncol. 2014 Aug 6;4:211. doi: 10.3389/fonc.2014.00211. eCollection 2014. Review. No abstract available.


Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma.

Capaccione KM, Hong X, Morgan KM, Liu W, Bishop JM, Liu L, Markert E, Deen M, Minerowicz C, Bertino JR, Allen T, Pine SR.

Oncotarget. 2014 Jun 15;5(11):3636-50.


Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines.

Liu W, Jeganathan G, Amiri S, Morgan KM, Ryan BM, Pine SR.

Mol Cancer. 2013 Nov 15;12(1):139. doi: 10.1186/1476-4598-12-139.


p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes.

Mondal AM, Horikawa I, Pine SR, Fujita K, Morgan KM, Vera E, Mazur SJ, Appella E, Vojtesek B, Blasco MA, Lane DP, Harris CC.

J Clin Invest. 2013 Dec;123(12):5247-57. doi: 10.1172/JCI70355. Epub 2013 Nov 15.


The Notch signaling pathway as a mediator of tumor survival.

Capaccione KM, Pine SR.

Carcinogenesis. 2013 Jul;34(7):1420-30. doi: 10.1093/carcin/bgt127. Epub 2013 Apr 12. Review.


Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy.

Patel SA, Ramkissoon SH, Bryan M, Pliner LF, Dontu G, Patel PS, Amiri S, Pine SR, Rameshwar P.

Sci Rep. 2012;2:906. doi: 10.1038/srep00906. Epub 2012 Nov 30.


MDM2 SNP285 does not antagonize the effect of SNP309 in lung cancer.

Ryan BM, Calhoun KM, Pine SR, Bowman ED, Robles AI, Ambs S, Harris CC.

Int J Cancer. 2012 Dec 1;131(11):2710-6. doi: 10.1002/ijc.27573. Epub 2012 Apr 27.


Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer.

Pine SR, Mechanic LE, Enewold L, Chaturvedi AK, Katki HA, Zheng YL, Bowman ED, Engels EA, Caporaso NE, Harris CC.

J Natl Cancer Inst. 2011 Jul 20;103(14):1112-22. doi: 10.1093/jnci/djr216. Epub 2011 Jun 17.


Admixture mapping of lung cancer in 1812 African-Americans.

Schwartz AG, Wenzlaff AS, Bock CH, Ruterbusch JJ, Chen W, Cote ML, Artis AS, Van Dyke AL, Land SJ, Harris CC, Pine SR, Spitz MR, Amos CI, Levin AM, McKeigue PM.

Carcinogenesis. 2011 Mar;32(3):312-7. doi: 10.1093/carcin/bgq252. Epub 2010 Nov 29.


C-reactive protein and risk of lung cancer.

Chaturvedi AK, Caporaso NE, Katki HA, Wong HL, Chatterjee N, Pine SR, Chanock SJ, Goedert JJ, Engels EA.

J Clin Oncol. 2010 Jun 1;28(16):2719-26. doi: 10.1200/JCO.2009.27.0454. Epub 2010 Apr 26.


Microenvironmental modulation of asymmetric cell division in human lung cancer cells.

Pine SR, Ryan BM, Varticovski L, Robles AI, Harris CC.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2195-200. doi: 10.1073/pnas.0909390107. Epub 2010 Jan 13.


Childhood exposure to secondhand smoke and functional mannose binding lectin polymorphisms are associated with increased lung cancer risk.

Olivo-Marston SE, Yang P, Mechanic LE, Bowman ED, Pine SR, Loffredo CA, Alberg AJ, Caporaso N, Shields PG, Chanock S, Wu Y, Jiang R, Cunningham J, Jen J, Harris CC.

Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3375-83. doi: 10.1158/1055-9965.EPI-09-0986.


p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence.

Fujita K, Mondal AM, Horikawa I, Nguyen GH, Kumamoto K, Sohn JJ, Bowman ED, Mathe EA, Schetter AJ, Pine SR, Ji H, Vojtesek B, Bourdon JC, Lane DP, Harris CC.

Nat Cell Biol. 2009 Sep;11(9):1135-42. doi: 10.1038/ncb1928. Epub 2009 Aug 23.


Lung cancer stem cells.

Pine SR, Marshall B, Varticovski L.

Dis Markers. 2008;24(4-5):257-66. Review.


Manganese superoxide dismutase gene coding region polymorphisms lack clinical incidence in general population.

Martin RC, Barker DF, Doll MA, Pine SR, Mechanic L, Bowman ED, Harris CC, Hein DW.

DNA Cell Biol. 2008 Jun;27(6):321-3. doi: 10.1089/dna.2007.0725.


Lung cancer survival and functional polymorphisms in MBL2, an innate-immunity gene.

Pine SR, Mechanic LE, Ambs S, Bowman ED, Chanock SJ, Loffredo C, Shields PG, Harris CC.

J Natl Cancer Inst. 2007 Sep 19;99(18):1401-9. Epub 2007 Sep 11.


Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome.

Pine SR, Guo Q, Yin C, Jayabose S, Druschel CM, Sandoval C.

Blood. 2007 Sep 15;110(6):2128-31. Epub 2007 Jun 18.


Lymphoproliferative clonal origin of AIDS-related non-Hodgkin's lymphoma.

Sabaawy HE, Sandoval C, Guo Q, Yin C, Kulangara A, Lee J, Wormser G, Jayabose S, Pine SR.

Leuk Lymphoma. 2007 Apr;48(4):812-5. No abstract available.


Down syndrome and GATA1-related transient leukemia.

Sandoval C, Pine SR.

J Pediatr. 2007 Mar;150(3):e34. No abstract available.


MDM2 SNP309 and SNP354 are not associated with lung cancer risk.

Pine SR, Mechanic LE, Bowman ED, Welsh JA, Chanock SC, Shields PG, Harris CC.

Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1559-61.


GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome.

Pine SR, Guo Q, Yin C, Jayabose S, Levendoglu-Tugal O, Ozkaynak MF, Sandoval C.

Leuk Res. 2005 Nov;29(11):1353-6.


Detection of central nervous system leukemia in children with acute lymphoblastic leukemia by real-time polymerase chain reaction.

Pine SR, Yin C, Matloub YH, Sabaawy HE, Sandoval C, Levendoglu-Tugal O, Ozkaynak MF, Jayabose S.

J Mol Diagn. 2005 Feb;7(1):127-32.


Tetrasomy 21 transient leukemia with a GATA1 mutation in a phenotypically normal trisomy 21 mosaic infant: case report and review of the literature.

Sandoval C, Pine SR, Guo Q, Sastry S, Stewart J, Kronn D, Jayabose S.

Pediatr Blood Cancer. 2005 Jan;44(1):85-91. Review.


Real-time quantitative PCR: standardized detection of minimal residual disease in pediatric acute lymphoblastic leukemia. Polymerase chain reaction.

Pine SR, Moy FH, Wiemels JL, Gill RK, Levendoglu-Tugal O, Ozkaynak MF, Sandoval C, Jayabose S.

J Pediatr Hematol Oncol. 2003 Feb;25(2):103-8.


TEL-AML1 fusion precedes differentiation to pre-B cells in childhood acute lymphoblastic leukemia.

Pine SR, Wiemels JL, Jayabose S, Sandoval C.

Leuk Res. 2003 Feb;27(2):155-64.


Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.

Wiemels JL, Leonard BC, Wang Y, Segal MR, Hunger SP, Smith MT, Crouse V, Ma X, Buffler PA, Pine SR.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15101-6. Epub 2002 Nov 1.


Cholesterol limits estrogen uptake by liposomes and erythrocyte membranes.

Jacobsohn MK, Bauder S, Pine SR, Jacobsohn GM.

Biochim Biophys Acta. 1994 Oct 12;1195(1):131-40.


Tax court denies deductions paid to malpractice trust.

Pine SR, Wright PB.

Risk Manage. 1986 Feb;33(2):18, 20. No abstract available.


Court of claims rules on deductibility of premiums paid to wholly-owned insurance subsidiaries.

Pine SR, Wright PB.

Risk Manage. 1985 Oct;32(10):14-5, 18. No abstract available.


IRS denies exemption to hospitals' SI trust.

Pine SR, Wright PB.

Risk Manage. 1984 Jul;31(7):14-5. No abstract available.


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