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Items: 1 to 50 of 146

1.

Selective cytotoxicity of a novel immunotoxin based on pulchellin A chain for cells expressing HIV envelope.

Sadraeian M, Guimarães FEG, Araújo APU, Worthylake DK, LeCour LJ, Pincus SH.

Sci Rep. 2017 Aug 8;7(1):7579. doi: 10.1038/s41598-017-08037-3.

2.

Identification of Human Anti-HIV gp160 Monoclonal Antibodies That Make Effective Immunotoxins.

Pincus SH, Song K, Maresh GA, Hamer DH, Dimitrov DS, Chen W, Zhang MY, Ghetie VF, Chan-Hui PY, Robinson JE, Vitetta ES.

J Virol. 2017 Jan 18;91(3). pii: e01955-16. doi: 10.1128/JVI.01955-16. Print 2017 Feb 1.

3.

Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160.

Pincus SH, Song K, Maresh GA, Frank A, Worthylake D, Chung HK, Polacino P, Hamer DH, Coyne CP, Rosenblum MG, Marks JW, Chen G, Weiss D, Ghetie V, Vitetta ES, Robinson JE, Hu SL.

J Virol. 2017 Jan 18;91(3). pii: e01360-16. doi: 10.1128/JVI.01360-16. Print 2017 Feb 1.

4.

Coupling Peptide Antigens to Virus-Like Particles or to Protein Carriers Influences the Th1/Th2 Polarity of the Resulting Immune Response.

Pomwised R, Intamaso U, Teintze M, Young M, Pincus SH.

Vaccines (Basel). 2016 May 5;4(2). pii: E15. doi: 10.3390/vaccines4020015.

5.

Recent advances in the development of vaccines against ricin.

Brey RN 3rd, Mantis NJ, Pincus SH, Vitetta ES, Smith LA, Roy CJ.

Hum Vaccin Immunother. 2016 May 3;12(5):1196-201. doi: 10.1080/21645515.2015.1124202. Epub 2016 Jan 25.

6.

Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin.

Pincus SH, Bhaskaran M, Brey RN 3rd, Didier PJ, Doyle-Meyers LA, Roy CJ.

Toxins (Basel). 2015 Jun 9;7(6):2121-33. doi: 10.3390/toxins7062121.

7.

Role of Fc in antibody-mediated protection from ricin toxin.

Pincus SH, Das A, Song K, Maresh GA, Corti M, Berry J.

Toxins (Basel). 2014 May 7;6(5):1512-25. doi: 10.3390/toxins6051512.

8.

Expression of the memory marker CD45RO on helper T cells in macaques.

Valentine M, Song K, Maresh GA, Mack H, Huaman MC, Polacino P, Ho O, Cristillo A, Kyung Chung H, Hu SL, Pincus SH.

PLoS One. 2013 Sep 4;8(9):e73969. doi: 10.1371/journal.pone.0073969. eCollection 2013.

9.

Antibody to ricin a chain hinders intracellular routing of toxin and protects cells even after toxin has been internalized.

Song K, Mize RR, Marrero L, Corti M, Kirk JM, Pincus SH.

PLoS One. 2013 Apr 24;8(4):e62417. doi: 10.1371/journal.pone.0062417. Print 2013.

10.

Improved guanide compounds which bind the CXCR4 co-receptor and inhibit HIV-1 infection.

Wilkinson RA, Pincus SH, Song K, Shepard JB, Weaver AJ Jr, Labib ME, Teintze M.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):2197-201. doi: 10.1016/j.bmcl.2013.01.107. Epub 2013 Jan 30.

11.

Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody.

Zhao Z, Worthylake D, LeCour L Jr, Maresh GA, Pincus SH.

PLoS One. 2012;7(12):e52613. doi: 10.1371/journal.pone.0052613. Epub 2012 Dec 19.

12.

Anti-HIV double variable domain immunoglobulins binding both gp41 and gp120 for targeted delivery of immunoconjugates.

Craig RB, Summa CM, Corti M, Pincus SH.

PLoS One. 2012;7(10):e46778. doi: 10.1371/journal.pone.0046778. Epub 2012 Oct 4.

13.

Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41.

Zhang MY, Yuan T, Li J, Rosa Borges A, Watkins JD, Guenaga J, Yang Z, Wang Y, Wilson R, Li Y, Polonis VR, Pincus SH, Ruprecht RM, Dimitrov DS.

PLoS One. 2012;7(9):e44241. doi: 10.1371/journal.pone.0044241. Epub 2012 Sep 10.

14.

Fine specificity and cross-reactions of monoclonal antibodies to group B streptococcal capsular polysaccharide type III.

Pincus SH, Moran E, Maresh G, Jennings HJ, Pritchard DG, Egan ML, Blixt O.

Vaccine. 2012 Jul 6;30(32):4849-58. doi: 10.1016/j.vaccine.2012.05.006. Epub 2012 May 23.

15.

Passive and active vaccination strategies to prevent ricin poisoning.

Pincus SH, Smallshaw JE, Song K, Berry J, Vitetta ES.

Toxins (Basel). 2011 Sep;3(9):1163-84. doi: 10.3390/toxins3091163. Epub 2011 Sep 15. Review.

16.

Animal models of ricin toxicosis.

Roy CJ, Song K, Sivasubramani SK, Gardner DJ, Pincus SH.

Curr Top Microbiol Immunol. 2012;357:243-57. doi: 10.1007/82_2011_173.

17.

Scholars' awards go mainly to men.

Lincoln AE, Pincus SH, Leboy PS.

Nature. 2011 Jan 27;469(7331):472. doi: 10.1038/469472a. No abstract available.

PMID:
21270876
18.

Novel compounds containing multiple guanide groups that bind the HIV coreceptor CXCR4.

Wilkinson RA, Pincus SH, Shepard JB, Walton SK, Bergin EP, Labib M, Teintze M.

Antimicrob Agents Chemother. 2011 Jan;55(1):255-63. doi: 10.1128/AAC.00709-10. Epub 2010 Oct 11.

19.

Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements.

Chen QY, Zhang T, Pincus SH, Wu S, Ricks D, Liu D, Sun Z, Maclaren N, Lan MS.

J Immunol. 2010 May 1;184(9):5047-54. doi: 10.4049/jimmunol.0901912. Epub 2010 Apr 2.

20.

Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model.

Roche JK, Stone MK, Gross LK, Lindner M, Seaner R, Pincus SH, Obrig TG.

Lab Invest. 2008 Nov;88(11):1178-91. doi: 10.1038/labinvest.2008.83. Epub 2008 Sep 8.

21.

Use of tissue culture cell lines to evaluate HIV antiviral resistance.

Krowicka H, Robinson JE, Clark R, Hager S, Broyles S, Pincus SH.

AIDS Res Hum Retroviruses. 2008 Jul;24(7):957-67. doi: 10.1089/aid.2007.0242.

22.

Double-blind trial of recombinant gamma-interferon versus placebo in the treatment of rheumatoid arthritis. 1989.

Cannon GW, Pincus SH, Emkey RD, Denes A, Cohen SA, Wolfe F, Saway PA, Jaffer AM, Weaver AL, Cogen L, Schindler JD.

Arthritis Rheum. 2008 Feb;58(2 Suppl):S79-88. doi: 10.1002/art.23361.

23.

Peptides selected from a phage display library with an HIV-neutralizing antibody elicit antibodies to HIV gp120 in rabbits, but not to the same epitope.

Wilkinson RA, Evans JR, Jacobs JM, Slunaker D, Pincus SH, Pinter A, Parkos CA, Burritt JB, Teintze M.

AIDS Res Hum Retroviruses. 2007 Nov;23(11):1416-27. doi: 10.1089/aid.2007.0027.

PMID:
18184085
24.

Oropharyngeal aspiration of ricin as a lung challenge model for evaluation of the therapeutic index of antibodies against ricin A-chain for post-exposure treatment.

Pratt TS, Pincus SH, Hale ML, Moreira AL, Roy CJ, Tchou-Wong KM.

Exp Lung Res. 2007 Oct-Nov;33(8-9):459-81.

PMID:
17994372
25.

Molecular preservation in Late Cretaceous sauropod dinosaur eggshells.

Schweitzer MH, Chiappe L, Garrido AC, Lowenstein JM, Pincus SH.

Proc Biol Sci. 2005 Apr 22;272(1565):775-84.

26.

Comparison of different microarray data analysis programs and description of a database for microarray data management.

Xu L, Maresh GA, Giardina J, Pincus SH.

DNA Cell Biol. 2004 Oct;23(10):643-51.

PMID:
15585122
27.

Immunological characteristics associated with the protective efficacy of antibodies to ricin.

Maddaloni M, Cooke C, Wilkinson R, Stout AV, Eng L, Pincus SH.

J Immunol. 2004 May 15;172(10):6221-8.

28.

A modified SCID mouse model of HIV infection with utility for testing anti-HIV therapies.

Pincus SH, Fang H, Wilkinson RA, Olson WC, Marcotte TK.

AIDS Res Hum Retroviruses. 2003 Oct;19(10):901-8.

PMID:
14585222
29.

The Veterans Affairs Learners' Perceptions Survey: the foundation for educational quality improvement.

Keitz SA, Holland GJ, Melander EH, Bosworth HB, Pincus SH; VA Learners' Perceptions Working Group.

Acad Med. 2003 Sep;78(9):910-7.

PMID:
14507624
30.

NMR studies of carbohydrates and carbohydrate-mimetic peptides recognized by an anti-group B Streptococcus antibody.

Johnson MA, Jaseja M, Zou W, Jennings HJ, Copie V, Pinto BM, Pincus SH.

J Biol Chem. 2003 Jul 4;278(27):24740-52. Epub 2003 Apr 16.

31.

In vivo efficacy of anti-glycoprotein 41, but not anti-glycoprotein 120, immunotoxins in a mouse model of HIV infection.

Pincus SH, Fang H, Wilkinson RA, Marcotte TK, Robinson JE, Olson WC.

J Immunol. 2003 Feb 15;170(4):2236-41.

32.

Identification of hypoglycemia in mice as a surrogate marker of ricin toxicosis.

Pincus SH, Eng L, Cooke CL, Maddaloni M.

Comp Med. 2002 Dec;52(6):530-3.

PMID:
12540166
33.

The VA National Quality Scholars Fellowship Program: current status, future directions.

Pincus SH, Wolff EM, Melander EH.

Qual Manag Health Care. 2002 Spring;10(3):71-6.

PMID:
12512468
34.

Identification of immunoreactive material in mammoth fossils.

Schweitzer M, Hill CL, Asara JM, Lane WS, Pincus SH.

J Mol Evol. 2002 Dec;55(6):696-705.

PMID:
12486528
35.

Thalidomide therapy for cicatricial pemphigoid.

Duong DJ, Moxley RT 3rd, Kellman RM, Pincus SH, Gaspari AA.

J Am Acad Dermatol. 2002 Aug;47(2 Suppl):S193-5.

PMID:
12140460
36.

Initial studies of the molecular basis of peptide mimicry of group B streptococcal type III capsular polysaccharide.

Pincus SH, Lepage SR, Jung RF, Massey JG, Jaseja M.

Int Rev Immunol. 2001;20(2):221-7.

PMID:
11878766
37.

In vivo testing of anti-HIV immunotoxins.

Pincus SH, Marcotte TK, Forsyth BM, Fang H.

Methods Mol Biol. 2001;166:277-94. Review. No abstract available.

PMID:
11217373
38.

11 Targeting HIV-Infected Cells.

Pincus SH.

Methods Mol Med. 2000;25:193-214. doi: 10.1385/1-59259-075-6:193.

PMID:
21318847
39.

Peptide ligands that bind IgM antibodies and block interaction with antigen.

Glee PM, Pincus SH, McNamer DK, Smith MJ, Burritt JB, Cutler JE.

J Immunol. 1999 Jul 15;163(2):826-33.

40.

Improved reproducibility of ELISA using a static-discharge pad.

Cassutt KJ, Pincus SH.

Biotechniques. 1998 Nov;25(5):801-2. No abstract available.

41.

Tazarotene 0.1% gel plus corticosteroid cream in the treatment of plaque psoriasis.

Lebwohl MG, Breneman DL, Goffe BS, Grossman JR, Ling MR, Milbauer J, Pincus SH, Sibbald RG, Swinyer LJ, Weinstein GD, Lew-Kaya DA, Lue JC, Gibson JR, Sefton J.

J Am Acad Dermatol. 1998 Oct;39(4 Pt 1):590-6.

PMID:
9777766
42.
43.

Operational stress control in the former Yugoslavia: a joint endeavor.

Pincus SH, Benedek DM.

Mil Med. 1998 Jun;163(6):358-62.

PMID:
9640029
44.

Peptides that mimic the group B streptococcal type III capsular polysaccharide antigen.

Pincus SH, Smith MJ, Jennings HJ, Burritt JB, Glee PM.

J Immunol. 1998 Jan 1;160(1):293-8.

45.

Immunologic cross-reaction between HIV type 1 p17 and Mycoplasma hyorhinis variable lipoprotein.

Pincus SH, Cole RL, Watson-McKown R, Pinter A, Honnen W, Cole B, Wise KS.

AIDS Res Hum Retroviruses. 1998 Mar 20;14(5):419-25.

PMID:
9546801
46.

Vaccine-specific antibody responses induced by HIV-1 envelope subunit vaccines.

Pincus SH, Messer KG, Cole R, Ireland R, VanCott TC, Pinter A, Schwartz DH, Graham BS, Gorse GJ.

J Immunol. 1997 Apr 1;158(7):3511-20.

PMID:
9120313
47.

Influence of endosome-destabilizing peptides on efficacy of anti-HIV immunotoxins.

Tolstikov VV, Cole R, Fang H, Pincus SH.

Bioconjug Chem. 1997 Jan-Feb;8(1):38-43.

PMID:
9026033
48.

Therapeutic potential of anti-HIV immunotoxins.

Pincus SH.

Antiviral Res. 1996 Dec;33(1):1-9. Review.

PMID:
8955848
49.

In vitro effects of anti-HIV immunotoxins directed against multiple epitopes on HIV type 1 envelope glycoprotein 160.

Pincus SH, Wehrly K, Cole R, Fang H, Lewis GK, McClure J, Conley AJ, Wahren B, Posner MR, Notkins AL, Tilley SA, Pinter A, Eiden L, Teintze M, Dorward D, Tolstikov VV.

AIDS Res Hum Retroviruses. 1996 Jul 20;12(11):1041-51.

PMID:
8827220
50.

Treatment of vulvar dermatoses.

Zellis S, Pincus SH.

Semin Dermatol. 1996 Mar;15(1):71-6. Review. No abstract available.

PMID:
8723828

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