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Items: 1 to 50 of 105

1.

Helicobacter pylori elicits B7H3 expression on gastric epithelial cells: Implications in local T cell regulation and subset development during infection.

Lina TT, Gonzalez J, Pinchuk IV, Beswick EJ, Reyes VE.

Clin Oncol Res. 2019;2(5). doi: 10.31487/j.cor.2019.05.05. Epub 2019 Oct 10.

2.

Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90+ (myo-)fibroblasts in Crohn's disease and regulate Th1/Th17 cell responses.

Aguirre JE, Beswick EJ, Grim C, Uribe G, Tafoya M, Chacon Palma G, Samedi V, McKee R, Villeger R, Fofanov Y, Cong Y, Yochum G, Koltun W, Powell D, Pinchuk IV.

Int Immunol. 2020 Jan 9;32(1):57-68. doi: 10.1093/intimm/dxz060.

PMID:
31633754
3.

[Radical cystectomy: therapeutic aspects of preoperative and early postoperative management].

Darenkov SP, Pinchuk IS, Proskokov AA, Trofimchuk AD, Fedulaev YN, Pinchuk TV, Makarova IV, Andreeva ON.

Urologiia. 2019 Sep;(4):44-50. Russian.

PMID:
31535804
4.

Laccase isoform diversity in basidiomycete Lentinus strigosus 1566: Potential for phenylpropanoid polymerization.

Kolomytseva MP, Myasoedova NM, Chernykh AM, Gaidina AS, Shebanova AD, Baskunov BP, Aschenbrenner J, Rosengarten JF, Renfeld ZV, Gasanov NB, Pinchuk IP, Classen T, Pietruszka J, Golovleva LA.

Int J Biol Macromol. 2019 Sep 15;137:1199-1210. doi: 10.1016/j.ijbiomac.2019.07.056. Epub 2019 Jul 8.

PMID:
31295487
5.

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study.

Pinchuk I, Weber D, Kochlik B, Stuetz W, Toussaint O, Debacq-Chainiaux F, Dollé MET, Jansen EHJM, Gonos ES, Sikora E, Breusing N, Gradinaru D, Sindlinger T, Moreno-Villanueva M, Bürkle A, Grune T, Lichtenberg D.

Redox Biol. 2019 Jun;24:101204. doi: 10.1016/j.redox.2019.101204. Epub 2019 Apr 15.

6.

MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth.

Phinney BB, Ray AL, Peretti AS, Jerman SJ, Grim C, Pinchuk IV, Beswick EJ.

Front Immunol. 2018 Sep 21;9:1857. doi: 10.3389/fimmu.2018.01857. eCollection 2018.

7.

Immunosuppression by Intestinal Stromal Cells.

Pinchuk IV, Powell DW.

Adv Exp Med Biol. 2018;1060:115-129. doi: 10.1007/978-3-319-78127-3_7. Review.

PMID:
30155625
8.

Lactobacillus rhamnosus GG increases cyclooxygenase-2 expression and prostaglandin E2 secretion in colonic myofibroblasts via a MyD88-dependent mechanism during homeostasis.

Uribe G, Villéger R, Bressollier P, Dillard RN, Worthley DL, Wang TC, Powell DW, Urdaci MC, Pinchuk IV.

Cell Microbiol. 2018 Nov;20(11):e12871. doi: 10.1111/cmi.12871. Epub 2018 Jul 26. Erratum in: Cell Microbiol. 2019 Aug;21(8):e13040.

9.

Expression of Programmed Death-Ligand 1 by Human Colonic CD90+ Stromal Cells Differs Between Ulcerative Colitis and Crohn's Disease and Determines Their Capacity to Suppress Th1 Cells.

Beswick EJ, Grim C, Singh A, Aguirre JE, Tafoya M, Qiu S, Rogler G, McKee R, Samedi V, Ma TY, Reyes VE, Powell DW, Pinchuk IV.

Front Immunol. 2018 May 30;9:1125. doi: 10.3389/fimmu.2018.01125. eCollection 2018.

10.

Oxidative stress, as assayed by a single test, cannot be used as a diagnostic tool.

Lichtenberg D, Pinchuk I, Weber D.

Biofactors. 2018 May;44(3):222-223. doi: 10.1002/biof.1420. Epub 2018 Mar 15. Review.

PMID:
29542835
11.

The cardiovascular benefits of indiscriminate supplementation of omega-3 fatty acids; meta-analysis and decision-making approach.

Leshno M, Goldbourt U, Pinchuk I, Lichtenberg D.

Int J Food Sci Nutr. 2018 Aug;69(5):549-556. doi: 10.1080/09637486.2017.1402868. Epub 2017 Nov 24.

PMID:
29171335
12.

Deletion of NF-κB/RelA in Angiotensin II-Sensitive Mesenchymal Cells Blocks Aortic Vascular Inflammation and Abdominal Aortic Aneurysm Formation.

Ijaz T, Sun H, Pinchuk IV, Milewicz DM, Tilton RG, Brasier AR.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1881-1890. doi: 10.1161/ATVBAHA.117.309863. Epub 2017 Aug 17.

13.

Deuterium kinetic isotope effect (DKIE) in copper-induced LDL peroxidation: Interrelated effects of on inhibition and propagation.

Pinchuk I, Lichtenberg D.

Chem Phys Lipids. 2017 Jun;205:42-47. doi: 10.1016/j.chemphyslip.2017.04.009. Epub 2017 Apr 26.

PMID:
28455203
14.

Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy.

Falik Zaccai TC, Savitzki D, Zivony-Elboum Y, Vilboux T, Fitts EC, Shoval Y, Kalfon L, Samra N, Keren Z, Gross B, Chasnyk N, Straussberg R, Mullikin JC, Teer JK, Geiger D, Kornitzer D, Bitterman-Deutsch O, Samson AO, Wakamiya M, Peterson JW, Kirtley ML, Pinchuk IV, Baze WB, Gahl WA, Kleta R, Anikster Y, Chopra AK.

Brain. 2017 Feb;140(2):370-386. doi: 10.1093/brain/aww295. Epub 2016 Dec 21.

15.

PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment.

Watts TL, Cui R, Szaniszlo P, Resto VA, Powell DW, Pinchuk IV.

J Transl Med. 2016 Dec 8;14(1):337.

16.

Switching from oral atypical antipsychotic monotherapy to paliperidone palmitate once-monthly in non-acute patients with schizophrenia: A prospective, open-label, interventional study.

Schreiner A, Caspi A, Bergmans P, Cherubin P, Keim S, Lara E, Pinchuk I, Schuepbach D, Suleman S, Hargarter L.

Psychopharmacology (Berl). 2017 Jan;234(1):3-13. doi: 10.1007/s00213-016-4445-0. Epub 2016 Nov 5.

17.

In Healthy Young Men, a Short Exhaustive Exercise Alters the Oxidative Stress Only Slightly, Independent of the Actual Fitness.

Finkler M, Hochman A, Pinchuk I, Lichtenberg D.

Oxid Med Cell Longev. 2016;2016:9107210. doi: 10.1155/2016/9107210. Epub 2016 Feb 17.

18.

Isolation of CD 90+ Fibroblast/Myofibroblasts from Human Frozen Gastrointestinal Specimens.

Johnson P, Beswick EJ, Chao C, Powell DW, Hellmich MR, Pinchuk IV.

J Vis Exp. 2016 Jan 31;(107):e53691. doi: 10.3791/53691.

19.

The effect of compartmentalization on the kinetics of transition metal ions-induced lipoprotein peroxidation.

Pinchuk I, Lichtenberg D.

Chem Phys Lipids. 2016 Feb;195:39-46. doi: 10.1016/j.chemphyslip.2015.11.004. Epub 2015 Dec 2.

PMID:
26631919
20.

[Importance of surgery of quick recovery program for surgical treatment of bladder tumors].

Darenkov SP, Kotov SV, Proskokov AA, Jusufov AG, Belomytcev SV, Badovskaya EV, Gubaidullin RR, Pinchuk IS.

Urologiia. 2015 Dec;(6):109-115. Review. Russian.

PMID:
28247690
21.

CD90(+) stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer.

Huynh PT, Beswick EJ, Coronado YA, Johnson P, O'Connell MR, Watts T, Singh P, Qiu S, Morris K, Powell DW, Pinchuk IV.

Int J Cancer. 2016 Apr 15;138(8):1971-81. doi: 10.1002/ijc.29939. Epub 2015 Dec 10.

22.

Blockade of MK2 is protective in inflammation-associated colorectal cancer development.

Ray AL, Castillo EF, Morris KT, Nofchissey RA, Weston LL, Samedi VG, Hanson JA, Gaestel M, Pinchuk IV, Beswick EJ.

Int J Cancer. 2016 Feb 1;138(3):770-5. doi: 10.1002/ijc.29716. Epub 2015 Aug 21.

23.

Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting protective NK cell, macrophage and T cell responses.

Morris KT, Castillo EF, Ray AL, Weston LL, Nofchissey RA, Hanson JA, Samedi VG, Pinchuk IV, Hudson LG, Beswick EJ.

Oncotarget. 2015 Sep 8;6(26):22338-47.

24.

Oxidative stress, the term and the concept.

Lichtenberg D, Pinchuk I.

Biochem Biophys Res Commun. 2015 Jun 5;461(3):441-4. doi: 10.1016/j.bbrc.2015.04.062. Epub 2015 Apr 21. Review.

PMID:
25911322
25.

Helicobacter pylori cag pathogenicity island's role in B7-H1 induction and immune evasion.

Lina TT, Alzahrani S, House J, Yamaoka Y, Sharpe AH, Rampy BA, Pinchuk IV, Reyes VE.

PLoS One. 2015 Mar 25;10(3):e0121841. doi: 10.1371/journal.pone.0121841. eCollection 2015.

26.

Role of intestinal myofibroblasts in HIV-associated intestinal collagen deposition and immune reconstitution following combination antiretroviral therapy.

Asmuth DM, Pinchuk IV, Wu J, Vargas G, Chen X, Mann S, Albanese A, Ma ZM, Saroufeem R, Melcher GP, Troia-Cancio P, Torok NJ, Miller CJ, Powell DW.

AIDS. 2015 May 15;29(8):877-88. doi: 10.1097/QAD.0000000000000636.

27.

Prolongation of the lag time preceding peroxidation of serum lipids: a measure of antioxidant capacity.

Pinchuk I, Lichtenberg D.

Methods Mol Biol. 2015;1208:171-80. doi: 10.1007/978-1-4939-1441-8_13.

PMID:
25323507
28.

miR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD.

Wu W, He C, Liu C, Cao AT, Xue X, Evans-Marin HL, Sun M, Fang L, Yao S, Pinchuk IV, Powell DW, Liu Z, Cong Y.

Gut. 2015 Nov;64(11):1755-64. doi: 10.1136/gutjnl-2014-307980. Epub 2014 Oct 3.

PMID:
25281418
29.

Effect of Helicobacter pylori on gastric epithelial cells.

Alzahrani S, Lina TT, Gonzalez J, Pinchuk IV, Beswick EJ, Reyes VE.

World J Gastroenterol. 2014 Sep 28;20(36):12767-80. doi: 10.3748/wjg.v20.i36.12767. Review.

30.

Immune evasion strategies used by Helicobacter pylori.

Lina TT, Alzahrani S, Gonzalez J, Pinchuk IV, Beswick EJ, Reyes VE.

World J Gastroenterol. 2014 Sep 28;20(36):12753-66. doi: 10.3748/wjg.v20.i36.12753. Review.

31.

TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells.

Beswick EJ, Johnson JR, Saada JI, Humen M, House J, Dann S, Qiu S, Brasier AR, Powell DW, Reyes VE, Pinchuk IV.

J Immunol. 2014 Sep 1;193(5):2218-29. doi: 10.4049/jimmunol.1203441. Epub 2014 Jul 28.

32.

Chronic macrophage migration inhibitory factor exposure induces mesenchymal epithelial transition and promotes gastric and colon cancers.

Morris KT, Nofchissey RA, Pinchuk IV, Beswick EJ.

PLoS One. 2014 Jun 2;9(6):e98656. doi: 10.1371/journal.pone.0098656. eCollection 2014.

33.

G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration.

Morris KT, Khan H, Ahmad A, Weston LL, Nofchissey RA, Pinchuk IV, Beswick EJ.

Br J Cancer. 2014 Mar 4;110(5):1211-20. doi: 10.1038/bjc.2013.822. Epub 2014 Jan 21.

34.

Analysis of the kinetics of lipid peroxidation in terms of characteristic time-points.

Pinchuk I, Lichtenberg D.

Chem Phys Lipids. 2014 Feb;178:63-76. doi: 10.1016/j.chemphyslip.2013.12.001. Epub 2013 Dec 11. Review.

PMID:
24333462
35.

CagA-dependent downregulation of B7-H2 expression on gastric mucosa and inhibition of Th17 responses during Helicobacter pylori infection.

Lina TT, Pinchuk IV, House J, Yamaoka Y, Graham DY, Beswick EJ, Reyes VE.

J Immunol. 2013 Oct 1;191(7):3838-46. doi: 10.4049/jimmunol.1300524. Epub 2013 Aug 30.

36.

The relationship between oxidative stress and exercise.

Finkler M, Lichtenberg D, Pinchuk I.

J Basic Clin Physiol Pharmacol. 2014 Feb;25(1):1-11. doi: 10.1515/jbcpp-2013-0082. Review.

PMID:
23959662
37.

Stromal cells induce Th17 during Helicobacter pylori infection and in the gastric tumor microenvironment.

Pinchuk IV, Morris KT, Nofchissey RA, Earley RB, Wu JY, Ma TY, Beswick EJ.

PLoS One. 2013;8(1):e53798. doi: 10.1371/journal.pone.0053798. Epub 2013 Jan 24.

38.

Inflammation, immunity, and vaccines for Helicobacter pylori infection.

Ihan A, Pinchuk IV, Beswick EJ.

Helicobacter. 2012 Sep;17 Suppl 1:16-21. doi: 10.1111/j.1523-5378.2012.00977.x. Review.

39.

Evaluation of antioxidants: scope, limitations and relevance of assays.

Pinchuk I, Shoval H, Dotan Y, Lichtenberg D.

Chem Phys Lipids. 2012 Sep;165(6):638-47. doi: 10.1016/j.chemphyslip.2012.05.003. Epub 2012 Jun 18. Review.

PMID:
22721987
40.

Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins.

Savidge TC, Urvil P, Oezguen N, Ali K, Choudhury A, Acharya V, Pinchuk I, Torres AG, English RD, Wiktorowicz JE, Loeffelholz M, Kumar R, Shi L, Nie W, Braun W, Herman B, Hausladen A, Feng H, Stamler JS, Pothoulakis C.

Nat Med. 2011 Aug 21;17(9):1136-41. doi: 10.1038/nm.2405.

41.

Role of gastric epithelial cell-derived transforming growth factor beta in reduced CD4+ T cell proliferation and development of regulatory T cells during Helicobacter pylori infection.

Beswick EJ, Pinchuk IV, Earley RB, Schmitt DA, Reyes VE.

Infect Immun. 2011 Jul;79(7):2737-45. doi: 10.1128/IAI.01146-10. Epub 2011 Apr 11.

42.

Human colonic myofibroblasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells.

Pinchuk IV, Beswick EJ, Saada JI, Boya G, Schmitt D, Raju GS, Brenmoehl J, Rogler G, Reyes VE, Powell DW.

Gastroenterology. 2011 Jun;140(7):2019-30. doi: 10.1053/j.gastro.2011.02.059. Epub 2011 Mar 2.

43.

Intestinal myofibroblasts: targets for stem cell therapy.

Mifflin RC, Pinchuk IV, Saada JI, Powell DW.

Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G684-96. doi: 10.1152/ajpgi.00474.2010. Epub 2011 Jan 20. Review.

44.

Mesenchymal cells of the intestinal lamina propria.

Powell DW, Pinchuk IV, Saada JI, Chen X, Mifflin RC.

Annu Rev Physiol. 2011;73:213-37. doi: 10.1146/annurev.physiol.70.113006.100646. Review.

45.

Ranking antioxidants based on their effect on human serum lipids peroxidation.

Pinchuk I, Shoval H, Bor A, Schnitzer E, Dotan Y, Lichtenberg D.

Chem Phys Lipids. 2011 Jan;164(1):42-8. doi: 10.1016/j.chemphyslip.2010.10.002. Epub 2010 Oct 15.

PMID:
20951686
46.

Intestinal mesenchymal cells.

Pinchuk IV, Mifflin RC, Saada JI, Powell DW.

Curr Gastroenterol Rep. 2010 Oct;12(5):310-8. doi: 10.1007/s11894-010-0135-y. Review.

47.

Staphylococcal enterotoxins.

Pinchuk IV, Beswick EJ, Reyes VE.

Toxins (Basel). 2010 Aug;2(8):2177-97. doi: 10.3390/toxins2082177. Epub 2010 Aug 18. Review.

48.

No evidence supports vitamin E indiscriminate supplementation.

Dotan Y, Lichtenberg D, Pinchuk I.

Biofactors. 2009 Nov-Dec;35(6):469-73. doi: 10.1002/biof.61. Review.

PMID:
19866453
49.

Decision analysis supports the paradigm that indiscriminate supplementation of vitamin E does more harm than good.

Dotan Y, Pinchuk I, Lichtenberg D, Leshno M.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1304-9. doi: 10.1161/ATVBAHA.108.178699. Epub 2009 Mar 12.

PMID:
19286632
50.

Degeneration of the pericryptal myofibroblast sheath by proinflammatory cytokines in inflammatory bowel diseases.

Francoeur C, Bouatrouss Y, Seltana A, Pinchuk IV, Vachon PH, Powell DW, Sawan B, Seidman EG, Beaulieu JF.

Gastroenterology. 2009 Jan;136(1):268-277.e3. doi: 10.1053/j.gastro.2008.10.014. Epub 2008 Oct 8.

PMID:
18976656

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