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Items: 37


Genomic and immunologic characterization of INI1-deficient pediatric cancers.

Forrest SJ, Al-Ibraheemi A, Doan D, Ward A, Clinton CM, Putra J, Pinches RS, Kadoch C, Chi S, Dubois SG, Leavey P, LeBoeuf NR, Mullen E, Collins N, Church AJ, Janeway KA.

Clin Cancer Res. 2020 Mar 2. pii: clincanres.3089.2019. doi: 10.1158/1078-0432.CCR-19-3089. [Epub ahead of print]


Mycobacteriophage ZoeJ: A broad host-range close relative of mycobacteriophage TM4.

Dedrick RM, Guerrero Bustamante CA, Garlena RA, Pinches RS, Cornely K, Hatfull GF.

Tuberculosis (Edinb). 2019 Mar;115:14-23. doi: 10.1016/ Epub 2019 Jan 16.


The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria.

Noble R, Christodoulou Z, Kyes S, Pinches R, Newbold CI, Recker M.

Elife. 2013 Sep 17;2:e01074. doi: 10.7554/eLife.01074.


Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation.

Lemieux JE, Kyes SA, Otto TD, Feller AI, Eastman RT, Pinches RA, Berriman M, Su XZ, Newbold CI.

Mol Microbiol. 2013 Nov;90(3):519-37. doi: 10.1111/mmi.12381. Epub 2013 Sep 30.


An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing.

Auburn S, Campino S, Clark TG, Djimde AA, Zongo I, Pinches R, Manske M, Mangano V, Alcock D, Anastasi E, Maslen G, Macinnis B, Rockett K, Modiano D, Newbold CI, Doumbo OK, Ou├ędraogo JB, Kwiatkowski DP.

PLoS One. 2011;6(7):e22213. doi: 10.1371/journal.pone.0022213. Epub 2011 Jul 18.


Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.

Recker M, Buckee CO, Serazin A, Kyes S, Pinches R, Christodoulou Z, Springer AL, Gupta S, Newbold CI.

PLoS Pathog. 2011 Mar;7(3):e1001306. doi: 10.1371/journal.ppat.1001306. Epub 2011 Mar 3.


Plasmodium falciparum infected erythrocytes induce hepcidin (HAMP) mRNA synthesis by peripheral blood mononuclear cells.

Armitage AE, Pinches R, Eddowes LA, Newbold CI, Drakesmith H.

Br J Haematol. 2009 Dec;147(5):769-71. doi: 10.1111/j.1365-2141.2009.07880.x. Epub 2009 Aug 31. No abstract available.


Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture.

Lemieux JE, Gomez-Escobar N, Feller A, Carret C, Amambua-Ngwa A, Pinches R, Day F, Kyes SA, Conway DJ, Holmes CC, Newbold CI.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7559-64. doi: 10.1073/pnas.0811829106. Epub 2009 Apr 17.


Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1.

Mackintosh CL, Christodoulou Z, Mwangi TW, Kortok M, Pinches R, Williams TN, Marsh K, Newbold CI.

Malar J. 2008 Aug 16;7:155. doi: 10.1186/1475-2875-7-155.


Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children.

Mackintosh CL, Mwangi T, Kinyanjui SM, Mosobo M, Pinches R, Williams TN, Newbold CI, Marsh K.

Int J Parasitol. 2008 Oct;38(12):1445-54. doi: 10.1016/j.ijpara.2008.03.009. Epub 2008 Apr 29.


MORN1 has a conserved role in asexual and sexual development across the apicomplexa.

Ferguson DJ, Sahoo N, Pinches RA, Bumstead JM, Tomley FM, Gubbels MJ.

Eukaryot Cell. 2008 Apr;7(4):698-711. doi: 10.1128/EC.00021-08. Epub 2008 Feb 29.


Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum.

Mourier T, Carret C, Kyes S, Christodoulou Z, Gardner PP, Jeffares DC, Pinches R, Barrell B, Berriman M, Griffiths-Jones S, Ivens A, Newbold C, Pain A.

Genome Res. 2008 Feb;18(2):281-92. Epub 2007 Dec 20.


Plasmodium falciparum var gene expression is developmentally controlled at the level of RNA polymerase II-mediated transcription initiation.

Kyes S, Christodoulou Z, Pinches R, Kriek N, Horrocks P, Newbold C.

Mol Microbiol. 2007 Feb;63(4):1237-47.


PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes.

Horrocks P, Pinches RA, Chakravorty SJ, Papakrivos J, Christodoulou Z, Kyes SA, Urban BC, Ferguson DJ, Newbold CI.

J Cell Sci. 2005 Jun 1;118(Pt 11):2507-18.


Variable var transition rates underlie antigenic variation in malaria.

Horrocks P, Pinches R, Christodoulou Z, Kyes SA, Newbold CI.

Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11129-34. Epub 2004 Jul 15.


Transcription of subtelomerically located var gene variant in Plasmodium falciparum appears to require the truncation of an adjacent var gene.

Horrocks P, Kyes S, Pinches R, Christodoulou Z, Newbold C.

Mol Biochem Parasitol. 2004 Apr;134(2):193-9.


Characterization of the pathway for transport of the cytoadherence-mediating protein, PfEMP1, to the host cell surface in malaria parasite-infected erythrocytes.

Kriek N, Tilley L, Horrocks P, Pinches R, Elford BC, Ferguson DJ, Lingelbach K, Newbold CI.

Mol Microbiol. 2003 Nov;50(4):1215-27.


A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern.

Kyes SA, Christodoulou Z, Raza A, Horrocks P, Pinches R, Rowe JA, Newbold CI.

Mol Microbiol. 2003 Jun;48(5):1339-48.


Stage-specific promoter activity from stably maintained episomes in Plasmodium falciparum.

Horrocks P, Pinches R, Kriek N, Newbold C.

Int J Parasitol. 2002 Sep;32(10):1203-6.


Effect of var gene disruption on switching in Plasmodium falciparum.

Horrocks P, Pinches R, Kyes S, Kriek N, Lee S, Christodoulou Z, Newbold CI.

Mol Microbiol. 2002 Aug;45(4):1131-41.


Febrile temperatures induce cytoadherence of ring-stage Plasmodium falciparum-infected erythrocytes.

Udomsangpetch R, Pipitaporn B, Silamut K, Pinches R, Kyes S, Looareesuwan S, Newbold C, White NJ.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11825-9. Epub 2002 Aug 12.


Stage-specific merozoite surface protein 2 antisense transcripts in Plasmodium falciparum.

Kyes S, Christodoulou Z, Pinches R, Newbold C.

Mol Biochem Parasitol. 2002 Aug 7;123(1):79-83. No abstract available.


Identification of a Plasmodium falciparum intercellular adhesion molecule-1 binding domain: a parasite adhesion trait implicated in cerebral malaria.

Smith JD, Craig AG, Kriek N, Hudson-Taylor D, Kyes S, Fagan T, Pinches R, Baruch DI, Newbold CI, Miller LH.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1766-71. Erratum in: Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12209. Fagen, T [corrected to Fagan, T].


A simple RNA analysis method shows var and rif multigene family expression patterns in Plasmodium falciparum.

Kyes S, Pinches R, Newbold C.

Mol Biochem Parasitol. 2000 Feb 5;105(2):311-5. No abstract available.


Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1.

Craig AG, Pinches R, Khan S, Roberts DJ, Turner GD, Newbold CI, Berendt AR.

Infect Immun. 1997 Nov;65(11):4580-5.


Characterization of two vaccinia CD36 recombinant-virus-generated monoclonal antibodies (10/5, 13/10): effects on malarial cytoadherence and platelet functions.

Daviet L, Craig AG, McGregor L, Pinches R, Wild TF, Berendt AR, Newbold CI, McGregor JL.

Eur J Biochem. 1997 Jan 15;243(1-2):344-9.


Variant antigens and endothelial receptor adhesion in Plasmodium falciparum.

Gardner JP, Pinches RA, Roberts DJ, Newbold CI.

Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3503-8.


Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes.

Smith JD, Chitnis CE, Craig AG, Roberts DJ, Hudson-Taylor DE, Peterson DS, Pinches R, Newbold CI, Miller LH.

Cell. 1995 Jul 14;82(1):101-10.


Molecular mechanisms of sequestration in malaria.

Berendt AR, Ferguson DJ, Gardner J, Turner G, Rowe A, McCormick C, Roberts D, Craig A, Pinches R, Elford BC, et al.

Parasitology. 1994;108 Suppl:S19-28. Review. No abstract available.


Inducible transport systems in the regulation of parasite growth in malaria-infected red blood cells.

Elford BC, Pinches RA.

Biochem Soc Trans. 1992 Nov;20(4):790-6. Review. No abstract available.


Rapid switching to multiple antigenic and adhesive phenotypes in malaria.

Roberts DJ, Craig AG, Berendt AR, Pinches R, Nash G, Marsh K, Newbold CI.

Nature. 1992 Jun 25;357(6380):689-92.


Characteristics of 86Rb+ transport in human erythrocytes infected with Plasmodium falciparum.

Kirk K, Ashworth KJ, Elford BC, Pinches RA, Ellory JC.

Biochim Biophys Acta. 1991 Jan 30;1061(2):305-8.


Heterogeneous and substrate-specific membrane transport pathways induced in malaria-infected erythrocytes.

Elford BC, Pinches RA, Newbold CI, Ellory JC.

Blood Cells. 1990;16(2-3):433-6. No abstract available.


Maternal and fetal metabolic effects of prolonged ritodrine infusion.

Bassett JM, Burks AH, Levine DH, Pinches RA, Visser GH.

Obstet Gynecol. 1985 Dec;66(6):755-61.


Effects of intravenous glycine infusion on plasma glucagon, insulin and metabolite concentrations in lambs before and after birth.

Bassett JM, Burks AH, Pinches R.

J Dev Physiol. 1983 Feb;5(1):51-61. No abstract available.


Glucagon and insulin release in the lamb before and after birth: effects of amino acids in vitro and in vivo.

Bassett JM, Madill D, Burks AH, Pinches RA.

J Dev Physiol. 1982 Dec;4(6):379-89.


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