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Items: 1 to 50 of 336

1.

Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23.

Kansara M, Thomson K, Pang P, Dutour A, Mirabello L, Acher F, Pin JP, Demicco EG, Yan J, Teng MWL, Smyth MJ, Thomas DM.

Cancer Discov. 2019 Sep 16. pii: CD-19-0154. doi: 10.1158/2159-8290.CD-19-0154. [Epub ahead of print]

PMID:
31527131
2.

Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer.

Xue L, Sun Q, Zhao H, Rovira X, Gai S, He Q, Pin JP, Liu J, Rondard P.

Nat Commun. 2019 Jun 24;10(1):2765. doi: 10.1038/s41467-019-10834-5.

3.

Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor.

Hajj M, De Vita T, Vol C, Renassia C, Bologna JC, Brabet I, Cazade M, Pastore M, Blahos J, Labesse G, Pin JP, Prézeau L.

Mol Pharmacol. 2019 Aug;96(2):233-246. doi: 10.1124/mol.118.113019. Epub 2019 Jun 12.

PMID:
31189666
4.

French Guidelines for the Management of Ambulatory Endovascular Procedures for Lower Extremity Peripheral Artery Disease.

Alimi Y, Hauguel A, Casbas L, Magnan PE, Pin JL, Sabatier J, Régnard O, Gouëffic Y; French Society of Vascular and Endovascular Surgery (SCVE).

Ann Vasc Surg. 2019 Aug;59:248-258. doi: 10.1016/j.avsg.2019.05.001. Epub 2019 May 25.

PMID:
31132446
5.

Context-dependent signalling of CXC chemokine receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3).

Heuninck J, Perpina Viciano C, Işbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C.

Mol Pharmacol. 2019 May 15. pii: mol.118.115477. doi: 10.1124/mol.118.115477. [Epub ahead of print]

6.

Cross-Linkable Liquid-Crystalline Biopolyesteramide as a Multifunctional Polymeric Platform Designed from Corn Oil Side-Stream Product of Bioethanol Industry.

Pin JM, Misra M, Mohanty AK.

Macromol Rapid Commun. 2019 Jul;40(13):e1900093. doi: 10.1002/marc.201900093. Epub 2019 May 8.

PMID:
31066487
7.

Time-Resolved FRET-Based Assays to Characterize G Protein-Coupled Receptor Hetero-oligomer Pharmacology.

Heuninck J, Hounsou C, Dupuis E, Trinquet E, Mouillac B, Pin JP, Bonnet D, Durroux T.

Methods Mol Biol. 2019;1947:151-168. doi: 10.1007/978-1-4939-9121-1_8.

PMID:
30969415
8.

GPCR interaction as a possible way for allosteric control between receptors.

Pin JP, Kniazeff J, Prézeau L, Liu JF, Rondard P.

Mol Cell Endocrinol. 2019 Apr 15;486:89-95. doi: 10.1016/j.mce.2019.02.019. Epub 2019 Mar 5. Review.

PMID:
30849406
9.

A high mucosal blocking score is associated with HIV protection.

Girard A, Rallón N, Benito JM, Jospin F, Rodriguez C, Chanut B, Benjelloun F, Del Romero J, Verrier B, Lucht F, Pin JJ, Genin C, Biasin M, Clerici M, Paul S.

AIDS. 2019 Mar 1;33(3):411-423. doi: 10.1097/QAD.0000000000002099.

PMID:
30703069
10.

HTRF® Total and Phospho-YAP (Ser127) Cellular Assays.

Zindel D, Vol C, Lecha O, Bequignon I, Bilgic M, Vereecke M, Charrier-Savournin F, Romier M, Trinquet E, Pin JP, Pannequin J, Roux T, Dupuis E, Prézeau L.

Methods Mol Biol. 2019;1893:153-166. doi: 10.1007/978-1-4939-8910-2_13.

PMID:
30565133
11.

Composites from renewable and sustainable resources: Challenges and innovations.

Mohanty AK, Vivekanandhan S, Pin JM, Misra M.

Science. 2018 Nov 2;362(6414):536-542. doi: 10.1126/science.aat9072. Epub 2018 Nov 1. Review.

PMID:
30385569
12.

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3.

Tora AS, Rovira X, Cao AM, Cabayé A, Olofsson L, Malhaire F, Scholler P, Baik H, Van Eeckhaut A, Smolders I, Rondard P, Margeat E, Acher F, Pin JP, Goudet C.

Neuropharmacology. 2018 Sep 15;140:275-286. doi: 10.1016/j.neuropharm.2018.08.011. Epub 2018 Aug 11.

PMID:
30102917
13.

Profiling of orthosteric and allosteric group-III metabotropic glutamate receptor ligands on various G protein-coupled receptors with Tag-lite® assays.

Belhocine A, Veglianese P, Hounsou C, Dupuis E, Acher F, Durroux T, Goudet C, Pin JP.

Neuropharmacology. 2018 Sep 15;140:233-245. doi: 10.1016/j.neuropharm.2018.07.032. Epub 2018 Aug 9.

PMID:
30099051
14.

Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics.

Møller TC, Hottin J, Clerté C, Zwier JM, Durroux T, Rondard P, Prézeau L, Royer CA, Pin JP, Margeat E, Kniazeff J.

Sci Rep. 2018 Jul 10;8(1):10414. doi: 10.1038/s41598-018-28682-6.

15.

Stereodynamic insight into the thermal history effects on poly(vinyl chloride) calorimetric sub-glass and glass transitions as a fragile glass model.

Pin JM, Behazin E, Misra M, Mohanty A.

Phys Chem Chem Phys. 2018 Jun 20;20(24):16333-16346. doi: 10.1039/c8cp00755a.

PMID:
29717310
16.

Fine Mapping the Interaction Between Dendritic Cell-Specific Intercellular Adhesion Molecule (ICAM)-3-Grabbing Nonintegrin and the Cytomegalovirus Envelope Glycoprotein B.

Chéneau C, Coulon F, Porkolab V, Fieschi F, Laurant S, Razanajaona-Doll D, Pin JJ, Borst EM, Messerle M, Bressollette-Bodin C, Halary F.

J Infect Dis. 2018 Jul 2;218(3):490-503. doi: 10.1093/infdis/jiy194.

17.

Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs.

Nasrallah C, Rottier K, Marcellin R, Compan V, Font J, Llebaria A, Pin JP, Banères JL, Lebon G.

Sci Rep. 2018 Mar 13;8(1):4407. doi: 10.1038/s41598-018-22729-4.

18.

Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.

Rivat C, Sar C, Mechaly I, Leyris JP, Diouloufet L, Sonrier C, Philipson Y, Lucas O, Mallié S, Jouvenel A, Tassou A, Haton H, Venteo S, Pin JP, Trinquet E, Charrier-Savournin F, Mezghrani A, Joly W, Mion J, Schmitt M, Pattyn A, Marmigère F, Sokoloff P, Carroll P, Rognan D, Valmier J.

Nat Commun. 2018 Mar 12;9(1):1042. doi: 10.1038/s41467-018-03496-2.

19.

Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites.

Selvam C, Lemasson IA, Brabet I, Oueslati N, Karaman B, Cabaye A, Tora AS, Commare B, Courtiol T, Cesarini S, McCort-Tranchepain I, Rigault D, Mony L, Bessiron T, McLean H, Leroux FR, Colobert F, Daniel H, Goupil-Lamy A, Bertrand HO, Goudet C, Pin JP, Acher FC.

J Med Chem. 2018 Mar 8;61(5):1969-1989. doi: 10.1021/acs.jmedchem.7b01438. Epub 2018 Feb 14.

PMID:
29397723
20.

Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator.

Font J, López-Cano M, Notartomaso S, Scarselli P, Di Prieto P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, Nicoletti F, Llebaria A, Ciruela F.

Elife. 2018 Jan 8;7. pii: e34752. doi: 10.7554/eLife.34752. No abstract available.

21.

Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers.

Stewart GD, Comps-Agrar L, Nørskov-Lauritsen LB, Pin JP, Kniazeff J.

Neuropharmacology. 2018 Jul 1;136(Pt A):92-101. doi: 10.1016/j.neuropharm.2017.12.042. Epub 2018 Jan 2.

PMID:
29305121
22.

Class C G protein-coupled receptors: reviving old couples with new partners.

Møller TC, Moreno-Delgado D, Pin JP, Kniazeff J.

Biophys Rep. 2017;3(4):57-63. doi: 10.1007/s41048-017-0036-9. Epub 2017 Feb 28.

23.

From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled Receptors.

Hounsou C, Baehr C, Gasparik V, Alili D, Belhocine A, Rodriguez T, Dupuis E, Roux T, Mann A, Heissler D, Pin JP, Durroux T, Bonnet D, Hibert M.

J Med Chem. 2018 Jan 11;61(1):174-188. doi: 10.1021/acs.jmedchem.7b01220. Epub 2017 Dec 22.

PMID:
29219316
24.

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.

Scholler P, Nevoltris D, de Bundel D, Bossi S, Moreno-Delgado D, Rovira X, Møller TC, El Moustaine D, Mathieu M, Blanc E, McLean H, Dupuis E, Mathis G, Trinquet E, Daniel H, Valjent E, Baty D, Chames P, Rondard P, Pin JP.

Nat Commun. 2017 Dec 6;8(1):1967. doi: 10.1038/s41467-017-01489-1.

25.

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.

Liu J, Zhang Z, Moreno-Delgado D, Dalton JA, Rovira X, Trapero A, Goudet C, Llebaria A, Giraldo J, Yuan Q, Rondard P, Huang S, Liu J, Pin JP.

Elife. 2017 Aug 10;6. pii: e26985. doi: 10.7554/eLife.26985.

26.

RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.

Christensen SB, Hone AJ, Roux I, Kniazeff J, Pin JP, Upert G, Servent D, Glowatzki E, McIntosh JM.

Front Cell Neurosci. 2017 Jul 21;11:219. doi: 10.3389/fncel.2017.00219. eCollection 2017.

27.

Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand.

Dalton JAR, Pin JP, Giraldo J.

Sci Rep. 2017 Jul 10;7(1):4944. doi: 10.1038/s41598-017-05095-5.

28.

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.

Moreno Delgado D, Møller TC, Ster J, Giraldo J, Maurel D, Rovira X, Scholler P, Zwier JM, Perroy J, Durroux T, Trinquet E, Prezeau L, Rondard P, Pin JP.

Elife. 2017 Jun 29;6. pii: e25233. doi: 10.7554/eLife.25233.

29.

Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.

Ayoub MA, Crépieux P, Koglin M, Parmentier M, Pin JP, Poupon A, Reiter E, Smit M, Steyaert J, Watier H, Wilkinson T.

MAbs. 2017 Jul;9(5):735-741. doi: 10.1080/19420862.2017.1325052. Epub 2017 May 5.

30.

Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator.

Font J, López-Cano M, Notartomaso S, Scarselli P, Di Pietro P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, Nicoletti F, Llebaria A, Ciruela F.

Elife. 2017 Apr 11;6. pii: e23545. doi: 10.7554/eLife.23545. Erratum in: Elife. 2018 Jan 08;7:.

31.

FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor.

Lecat-Guillet N, Monnier C, Rovira X, Kniazeff J, Lamarque L, Zwier JM, Trinquet E, Pin JP, Rondard P.

Cell Chem Biol. 2017 Mar 16;24(3):360-370. doi: 10.1016/j.chembiol.2017.02.011. Epub 2017 Mar 9.

32.

Neutralizing and Targeting Properties of a New Set of α4β7-Specific Antibodies Are Influenced by Their Isotype.

Girard A, Jelicic K, Van Ryk D, Rochereau N, Cicala C, Arthos J, Noailly B, Genin C, Verrier B, Laurant S, Razanajaoana-Doll D, Pin JJ, Paul S.

J Acquir Immune Defic Syndr. 2017 May 1;75(1):118-127. doi: 10.1097/QAI.0000000000001307.

PMID:
28177967
33.

Stereodynamic control of star-epoxy/anhydride crosslinking actuated by liquid-crystalline phase transitions.

Pin JM, Mija A, Sbirrazzuoli N.

Soft Matter. 2017 Mar 8;13(10):1956-1965. doi: 10.1039/c6sm02624a.

PMID:
28170018
34.

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals.

Gómez-Santacana X, Pittolo S, Rovira X, Lopez M, Zussy C, Dalton JA, Faucherre A, Jopling C, Pin JP, Ciruela F, Goudet C, Giraldo J, Gorostiza P, Llebaria A.

ACS Cent Sci. 2017 Jan 25;3(1):81-91. doi: 10.1021/acscentsci.6b00353. Epub 2016 Dec 19.

35.

HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.

Scholler P, Moreno-Delgado D, Lecat-Guillet N, Doumazane E, Monnier C, Charrier-Savournin F, Fabre L, Chouvet C, Soldevila S, Lamarque L, Donsimoni G, Roux T, Zwier JM, Trinquet E, Rondard P, Pin JP.

Nat Chem Biol. 2017 Apr;13(4):372-380. doi: 10.1038/nchembio.2286. Epub 2017 Jan 30.

PMID:
28135236
36.

Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation.

Gómez-Santacana X, Dalton JAR, Rovira X, Pin JP, Goudet C, Gorostiza P, Giraldo J, Llebaria A.

Eur J Med Chem. 2017 Feb 15;127:567-576. doi: 10.1016/j.ejmech.2017.01.013. Epub 2017 Jan 12.

PMID:
28109949
37.

Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4.

Zussy C, Gómez-Santacana X, Rovira X, De Bundel D, Ferrazzo S, Bosch D, Asede D, Malhaire F, Acher F, Giraldo J, Valjent E, Ehrlich I, Ferraguti F, Pin JP, Llebaria A, Goudet C.

Mol Psychiatry. 2018 Mar;23(3):509-520. doi: 10.1038/mp.2016.223. Epub 2016 Dec 20.

PMID:
27994221
38.

Synthesis of Glycerol-Based Biopolyesters as Toughness Enhancers for Polylactic Acid Bioplastic through Reactive Extrusion.

Valerio O, Pin JM, Misra M, Mohanty AK.

ACS Omega. 2016 Dec 19;1(6):1284-1295. doi: 10.1021/acsomega.6b00325. eCollection 2016 Dec 31.

39.

Organization and functions of mGlu and GABAB receptor complexes.

Pin JP, Bettler B.

Nature. 2016 Dec 1;540(7631):60-68. doi: 10.1038/nature20566. Review.

PMID:
27905440
40.

Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling.

Zindel D, Engel S, Bottrill AR, Pin JP, Prézeau L, Tobin AB, Bünemann M, Krasel C, Butcher AJ.

Biochem J. 2016 Nov 15;473(22):4173-4192. Epub 2016 Sep 13.

41.

OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity.

Rovira X, Trapero A, Pittolo S, Zussy C, Faucherre A, Jopling C, Giraldo J, Pin JP, Gorostiza P, Goudet C, Llebaria A.

Cell Chem Biol. 2016 Aug 18;23(8):929-34. doi: 10.1016/j.chembiol.2016.06.013. Epub 2016 Jul 28.

42.

Lethal coronary air embolism caused by the removal of a double-lumen hemodialysis catheter: a case report.

Mun SH, An DA, Choi HJ, Kim TH, Pin JW, Ko DC.

Korean J Anesthesiol. 2016 Jun;69(3):296-300. doi: 10.4097/kjae.2016.69.3.296. Epub 2016 Jun 1.

43.

Negative association between autoantibodies against IL-17, IL-17/anti-IL-17 antibody immune complexes and destruction in rheumatoid arthritis.

Ndongo-Thiam N, Clement A, Pin JJ, Razanajaona-Doll D, Miossec P.

Ann Rheum Dis. 2016 Jul;75(7):1420-2. doi: 10.1136/annrheumdis-2016-209149. Epub 2016 Apr 29. No abstract available.

PMID:
27130907
44.

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques.

Avalos CR, Price SL, Forsyth ER, Pin JN, Shirk EN, Bullock BT, Queen SE, Li M, Gellerup D, O'Connor SL, Zink MC, Mankowski JL, Gama L, Clements JE.

J Virol. 2016 May 27;90(12):5643-5656. doi: 10.1128/JVI.00290-16. Print 2016 Jun 15.

45.

Effectiveness of applying continuous positive airway pressure in a patient with paradoxical vocal fold movement after endotracheal extubation: a case report.

Shin YH, Song KL, Ko DC, Pin JW, Ryu KH, Kim HS.

Korean J Anesthesiol. 2016 Feb;69(1):84-7. doi: 10.4097/kjae.2016.69.1.84. Epub 2016 Jan 28.

46.

New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.

Huynh TH, Erichsen MN, Tora AS, Goudet C, Sagot E, Assaf Z, Thomsen C, Brodbeck R, Stensbøl TB, Bjørn-Yoshimoto WE, Nielsen B, Pin JP, Gefflaut T, Bunch L.

J Med Chem. 2016 Feb 11;59(3):914-24. doi: 10.1021/acs.jmedchem.5b01333. Epub 2016 Jan 27.

PMID:
26814576
47.

A negative allosteric modulator modulates GABAB-receptor signalling through GB2 subunits.

Sun B, Chen L, Liu L, Xia Z, Pin JP, Nan F, Liu J.

Biochem J. 2016 Mar 15;473(6):779-87. doi: 10.1042/BJ20150979. Epub 2016 Jan 15.

PMID:
26772870
48.

Copolymerization as a Strategy to Combine Epoxidized Linseed Oil and Furfuryl Alcohol: The Design of a Fully Bio-Based Thermoset.

Pin JM, Guigo N, Vincent L, Sbirrazzuoli N, Mija A.

ChemSusChem. 2015 Dec 21;8(24):4149-61. doi: 10.1002/cssc.201501259. Epub 2015 Dec 9.

PMID:
26663869
49.

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective.

Dalton JA, Lans I, Rovira X, Malhaire F, Gómez-Santacana X, Pittolo S, Gorostiza P, Llebaria A, Goudet C, Pin JP, Giraldo J.

Curr Neuropharmacol. 2016;14(5):441-54.

50.

Characterization of a novel canine T-cell line established from a spontaneously occurring aggressive T-cell lymphoma with large granular cell morphology.

Bonnefont-Rebeix C, Fournel-Fleury C, Ponce F, Belluco S, Watrelot D, Bouteille SE, Rapiteau S, Razanajaona-Doll D, Pin JJ, Leroux C, Marchal T.

Immunobiology. 2016 Jan;221(1):12-22. doi: 10.1016/j.imbio.2015.08.007. Epub 2015 Aug 24.

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