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Items: 40

1.

The pancreas-specific form of secretory pathway calcium ATPase 2 regulates multiple pathways involved in calcium homeostasis.

Fenech MA, Carter MM, Stathopulos PB, Pin CL.

Biochim Biophys Acta Mol Cell Res. 2020 Jan;1867(1):118567. doi: 10.1016/j.bbamcr.2019.118567. Epub 2019 Oct 30.

PMID:
31676354
2.

Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.

Luo Y, Yang Y, Liu M, Wang D, Wang F, Bi Y, Ji J, Li S, Liu Y, Chen R, Huang H, Wang X, Swidnicka-Siergiejko AK, Janowitz T, Beyaz S, Wang G, Xu S, Bialkowska AB, Luo CK, Pin CL, Liang G, Lu X, Wu M, Shroyer KR, Wolff RA, Plunkett W, Ji B, Li Z, Li E, Li X, Yang VW, Logsdon CD, Abbruzzese JL, Lu W.

Gastroenterology. 2019 Nov;157(5):1413-1428.e11. doi: 10.1053/j.gastro.2019.07.030. Epub 2019 Jul 25.

PMID:
31352001
3.

18F-Labeled PET Probe Targeting Enhancer of Zeste Homologue 2 (EZH2) for Cancer Imaging.

Yu L, Despotovic N, Kovacs MS, Pin CL, Luyt LG.

ACS Med Chem Lett. 2019 Feb 27;10(3):334-340. doi: 10.1021/acsmedchemlett.8b00613. eCollection 2019 Mar 14.

PMID:
30891136
4.

The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.

Young CC, Baker RM, Howlett CJ, Hryciw T, Herman JE, Higgs D, Gibbons R, Crawford H, Brown A, Pin CL.

Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):93-113. doi: 10.1016/j.jcmgh.2018.09.004. eCollection 2019.

5.

Epigenetics of gastrointestinal diseases: notes from a workshop.

Marks DL, Olson RL, Urrutia R, Billadeau DD, Roy N, Calin GA, Fabbri M, Koutsioumpa M, Iliopoulos D, Ordog T, Huebert R, Sarmento O, Bamidele AO, Faubion W, Lomberk GL, Siveke J, Ahuja N, Iovanna J, Hlady RA, Robertson K, Kisiel J, Pin CL, Fernandez-Zapico ME.

Epigenetics. 2018;13(4):449-457. doi: 10.1080/15592294.2018.1464351. Epub 2018 Jul 30.

6.

Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice.

Fazio EN, Young CC, Toma J, Levy M, Berger KR, Johnson CL, Mehmood R, Swan P, Chu A, Cregan SP, Dilworth FJ, Howlett CJ, Pin CL.

Mol Biol Cell. 2017 Sep 1;28(18):2347-2359. doi: 10.1091/mbc.E17-04-0254. Epub 2017 Jul 12.

7.

Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas.

Kim M, Deacon P, Tirona RG, Kim RB, Pin CL, Meyer Zu Schwabedissen HE, Wang R, Schwarz UI.

Histochem Cell Biol. 2017 Oct;148(4):345-357. doi: 10.1007/s00418-017-1580-6. Epub 2017 May 10.

PMID:
28493059
8.

A Fibroblast Growth Factor 21-Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease.

Woolsey SJ, Beaton MD, Mansell SE, Leon-Ponte M, Yu J, Pin CL, Adams PC, Kim RB, Tirona RG.

Mol Pharmacol. 2016 Oct;90(4):437-46. doi: 10.1124/mol.116.104687. Epub 2016 Aug 1.

PMID:
27482056
9.

Atp2c2 Is Transcribed From a Unique Transcriptional Start Site in Mouse Pancreatic Acinar Cells.

Fenech MA, Sullivan CM, Ferreira LT, Mehmood R, MacDonald WA, Stathopulos PB, Pin CL.

J Cell Physiol. 2016 Dec;231(12):2768-78. doi: 10.1002/jcp.25391. Epub 2016 Apr 21.

PMID:
27017909
10.

Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis.

Moon PM, Penuela S, Barr K, Khan S, Pin CL, Welch I, Attur M, Abramson SB, Laird DW, Beier F.

J Mol Med (Berl). 2015 Aug;93(8):845-56. doi: 10.1007/s00109-015-1311-1. Epub 2015 Jul 4.

11.

Acinar cell reprogramming: a clinically important target in pancreatic disease.

Pin CL, Ryan JF, Mehmood R.

Epigenomics. 2015;7(2):267-81. doi: 10.2217/epi.14.83. Review.

PMID:
25942535
12.

Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21.

Assini JM, Mulvihill EE, Burke AC, Sutherland BG, Telford DE, Chhoker SS, Sawyez CG, Drangova M, Adams AC, Kharitonenkov A, Pin CL, Huff MW.

Endocrinology. 2015 Jun;156(6):2087-102. doi: 10.1210/en.2014-2003. Epub 2015 Mar 16.

PMID:
25774553
13.

Silencing of the Fibroblast growth factor 21 gene is an underlying cause of acinar cell injury in mice lacking MIST1.

Johnson CL, Mehmood R, Laing SW, Stepniak CV, Kharitonenkov A, Pin CL.

Am J Physiol Endocrinol Metab. 2014 Apr 15;306(8):E916-28. doi: 10.1152/ajpendo.00559.2013. Epub 2014 Feb 18.

14.

Epigenetic reprogramming in Mist1(-/-) mice predicts the molecular response to cerulein-induced pancreatitis.

Mehmood R, Varga G, Mohanty SQ, Laing SW, Lu Y, Johnson CL, Kharitonenkov A, Pin CL.

PLoS One. 2014 Jan 21;9(1):e84182. doi: 10.1371/journal.pone.0084182. eCollection 2014.

15.

Comparison of the clonality of urothelial carcinoma developing in the upper urinary tract and those developing in the bladder.

Wang Y, Lang MR, Pin CL, Izawa JI.

Springerplus. 2013 Aug 28;2:412. doi: 10.1186/2193-1801-2-412. eCollection 2013.

16.

Activation of protein kinase Cδ leads to increased pancreatic acinar cell dedifferentiation in the absence of MIST1.

Johnson CL, Peat JM, Volante SN, Wang R, McLean CA, Pin CL.

J Pathol. 2012 Nov;228(3):351-65. doi: 10.1002/path.4015. Epub 2012 May 2.

PMID:
22374815
17.

The absence of MIST1 leads to increased ethanol sensitivity and decreased activity of the unfolded protein response in mouse pancreatic acinar cells.

Alahari S, Mehmood R, Johnson CL, Pin CL.

PLoS One. 2011;6(12):e28863. doi: 10.1371/journal.pone.0028863. Epub 2011 Dec 28.

18.

Embryo collection induces transient activation of XBP1 arm of the ER stress response while embryo vitrification does not.

Abraham T, Pin CL, Watson AJ.

Mol Hum Reprod. 2012 May;18(5):229-42. doi: 10.1093/molehr/gar076. Epub 2011 Dec 7.

PMID:
22155729
19.

Stanniocalcin 2 alters PERK signalling and reduces cellular injury during cerulein induced pancreatitis in mice.

Fazio EN, Dimattia GE, Chadi SA, Kernohan KD, Pin CL.

BMC Cell Biol. 2011 May 5;12:17. doi: 10.1186/1471-2121-12-17.

20.

MIST1 regulates the pancreatic acinar cell expression of Atp2c2, the gene encoding secretory pathway calcium ATPase 2.

Garside VC, Kowalik AS, Johnson CL, DiRenzo D, Konieczny SF, Pin CL.

Exp Cell Res. 2010 Oct 15;316(17):2859-70. doi: 10.1016/j.yexcr.2010.06.014. Epub 2010 Jun 23.

21.

Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice.

Johnson CL, Weston JY, Chadi SA, Fazio EN, Huff MW, Kharitonenkov A, Köester A, Pin CL.

Gastroenterology. 2009 Nov;137(5):1795-804. doi: 10.1053/j.gastro.2009.07.064. Epub 2009 Aug 5.

PMID:
19664632
22.

Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation.

Bhattacharya D, Cheah MT, Franco CB, Hosen N, Pin CL, Sha WC, Weissman IL.

J Immunol. 2007 Nov 15;179(10):6808-19.

23.

Identification of a transcription factor, BHLHB8, involved in mouse seminal vesicle epithelium differentiation and function.

Pin CL, Johnson CL, Rade B, Kowalik AS, Garside VC, Everest ME.

Biol Reprod. 2008 Jan;78(1):91-100. Epub 2007 Sep 26.

PMID:
17901072
24.

The role of the type I insulin-like growth factor receptor (IGF-IR) in glomerular integrity.

Bridgewater DJ, Dionne JM, Butt MJ, Pin CL, Matsell DG.

Growth Horm IGF Res. 2008 Feb;18(1):26-37. Epub 2007 Aug 3.

PMID:
17689124
25.
26.

Mist1-null mice are resistant to streptozotocin-induced beta cell damage.

Fazio EN, Pin CL.

Biochem Biophys Res Commun. 2007 Feb 16;353(3):823-8. Epub 2006 Dec 22.

PMID:
17196162
27.

Mice lacking the transcription factor Mist1 exhibit an altered stress response and increased sensitivity to caerulein-induced pancreatitis.

Kowalik AS, Johnson CL, Chadi SA, Weston JY, Fazio EN, Pin CL.

Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1123-32. Epub 2006 Dec 14.

28.

Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1.

Fazio EN, Everest M, Colman R, Wang R, Pin CL.

J Endocrinol. 2005 Dec;187(3):407-18.

PMID:
16423820
29.

Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma.

Tuveson DA, Zhu L, Gopinathan A, Willis NA, Kachatrian L, Grochow R, Pin CL, Mitin NY, Taparowsky EJ, Gimotty PA, Hruban RH, Jacks T, Konieczny SF.

Cancer Res. 2006 Jan 1;66(1):242-7.

30.
31.

Exocrine specific expression of Connexin32 is dependent on the basic helix-loop-helix transcription factor Mist1.

Rukstalis JM, Kowalik A, Zhu L, Lidington D, Pin CL, Konieczny SF.

J Cell Sci. 2003 Aug 15;116(Pt 16):3315-25. Epub 2003 Jun 26.

32.

A fast fiber enhancer exists in the muscle regulatory factor 4 gene promoter.

Pin CL, Konieczny SF.

Biochem Biophys Res Commun. 2002 Nov 22;299(1):7-13.

PMID:
12435381
33.

Embryonic and fetal rat myoblasts form different muscle fiber types in an ectopic in vivo environment.

Pin CL, Hrycyshyn AW, Rogers KA, Rushlow WJ, Merrifield PA.

Dev Dyn. 2002 Jul;224(3):253-66.

34.

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.

Pin CL, Rukstalis JM, Johnson C, Konieczny SF.

J Cell Biol. 2001 Nov 12;155(4):519-30. Epub 2001 Nov 5.

35.

Mist1 expression is a common link among serous exocrine cells exhibiting regulated exocytosis.

Pin CL, Bonvissuto AC, Konieczny SF.

Anat Rec. 2000 Jun 1;259(2):157-67.

36.

Cloning of the murine Mist1 gene and assignment to mouse chromosome band 5G2-5G3.

Pin CL, Lemercier C, Konieczny SF.

Cytogenet Cell Genet. 1999;86(3-4):219-22.

PMID:
10575209
37.
39.

Distal regulatory elements control MRF4 gene expression in early and late myogenic cell populations.

Pin CL, Ludolph DC, Cooper ST, Klocke BJ, Merlie JP, Konieczny SF.

Dev Dyn. 1997 Mar;208(3):299-312.

40.

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