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Items: 43

1.

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.

Goiran T, Duplan E, Chami M, Bourgeois A, El Manaa W, Rouland L, Dunys J, Lauritzen I, You H, Stambolic V, Biféri MG, Barkats M, Pimplikar SW, Sergeant N, Colin M, Morais VA, Pardossi-Piquard R, Checler F, Alves da Costa C.

Biol Psychiatry. 2018 Mar 1;83(5):416-427. doi: 10.1016/j.biopsych.2017.04.011. Epub 2017 May 3.

2.

Multi-omics and Alzheimer's disease: a slower but surer path to an efficacious therapy?

Pimplikar SW.

Am J Physiol Cell Physiol. 2017 Jul 1;313(1):C1-C2. doi: 10.1152/ajpcell.00109.2017. Epub 2017 May 17. No abstract available.

3.

Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in Mice.

Ghosal K, Fan Q, Dawson HN, Pimplikar SW.

PLoS One. 2016 Jul 26;11(7):e0159435. doi: 10.1371/journal.pone.0159435. eCollection 2016.

4.

Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio.

Morris JK, Chomyk A, Song P, Parker N, Deckard S, Trapp BD, Pimplikar SW, Dutta R.

Invert Neurosci. 2015 Sep;15(3):4. doi: 10.1007/s10158-015-0180-1. Epub 2015 Jul 10.

PMID:
26159098
5.

JNK-interacting protein 1 mediates Alzheimer's-like pathological features in AICD-transgenic mice.

Margevicius DR, Bastian C, Fan Q, Davis RJ, Pimplikar SW.

Neurobiol Aging. 2015 Aug;36(8):2370-9. doi: 10.1016/j.neurobiolaging.2015.04.013. Epub 2015 Apr 30.

PMID:
26022769
6.

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

Jay TR, Miller CM, Cheng PJ, Graham LC, Bemiller S, Broihier ML, Xu G, Margevicius D, Karlo JC, Sousa GL, Cotleur AC, Butovsky O, Bekris L, Staugaitis SM, Leverenz JB, Pimplikar SW, Landreth GE, Howell GR, Ransohoff RM, Lamb BT.

J Exp Med. 2015 Mar 9;212(3):287-95. doi: 10.1084/jem.20142322. Epub 2015 Mar 2.

7.

Neuroinflammation in Alzheimer's disease: from pathogenesis to a therapeutic target.

Pimplikar SW.

J Clin Immunol. 2014 Jul;34 Suppl 1:S64-9. doi: 10.1007/s10875-014-0032-5. Epub 2014 Apr 8. Review.

PMID:
24711006
8.

Clinical and biomarker changes in Alzheimer's disease.

Pimplikar SW.

N Engl J Med. 2012 Nov 22;367(21):2050-1; author reply 2051-2. doi: 10.1056/NEJMc1211767. No abstract available.

PMID:
23171105
9.

The apolipoprotein-E-mimetic COG112 protects amyloid precursor protein intracellular domain-overexpressing animals from Alzheimer's disease-like pathological features.

Ghosal K, Stathopoulos A, Thomas D, Phenis D, Vitek MP, Pimplikar SW.

Neurodegener Dis. 2013;12(1):51-8. doi: 10.1159/000341299. Epub 2012 Sep 7.

PMID:
22965147
10.

Knockdown of amyloid precursor protein in zebrafish causes defects in motor axon outgrowth.

Song P, Pimplikar SW.

PLoS One. 2012;7(4):e34209. doi: 10.1371/journal.pone.0034209. Epub 2012 Apr 24.

11.

Amyloid precursor protein: more than just neurodegeneration.

Pimplikar SW, Ghosal K.

Stem Cell Res Ther. 2011 Oct 14;2(5):39. doi: 10.1186/scrt80.

12.

Amyloid-independent mechanisms in Alzheimer's disease pathogenesis.

Pimplikar SW, Nixon RA, Robakis NK, Shen J, Tsai LH.

J Neurosci. 2010 Nov 10;30(45):14946-54. doi: 10.1523/JNEUROSCI.4305-10.2010. Review.

13.

Detection of APP intracellular domain in brain tissue.

Pimplikar SW, Suryanarayana A.

Methods Mol Biol. 2011;670:85-91. doi: 10.1007/978-1-60761-744-0_7.

PMID:
20967585
14.

When neurogenesis encounters aging and disease.

Lazarov O, Mattson MP, Peterson DA, Pimplikar SW, van Praag H.

Trends Neurosci. 2010 Dec;33(12):569-79. doi: 10.1016/j.tins.2010.09.003. Epub 2010 Oct 18. Review.

15.

APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation.

Ghosal K, Stathopoulos A, Pimplikar SW.

PLoS One. 2010 Jul 30;5(7):e11866. doi: 10.1371/journal.pone.0011866.

16.

Aging and excitotoxic stress exacerbate neural circuit reorganization in amyloid precursor protein intracellular domain transgenic mice.

Ghosal K, Pimplikar SW.

Neurobiol Aging. 2011 Dec;32(12):2320.e1-9. doi: 10.1016/j.neurobiolaging.2010.04.020. Epub 2010 May 20.

17.

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.

Ghosal K, Vogt DL, Liang M, Shen Y, Lamb BT, Pimplikar SW.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18367-72. doi: 10.1073/pnas.0907652106. Epub 2009 Oct 16.

18.

Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain.

Vogt DL, Thomas D, Galvan V, Bredesen DE, Lamb BT, Pimplikar SW.

Neurobiol Aging. 2011 Sep;32(9):1725-9. doi: 10.1016/j.neurobiolaging.2009.09.002. Epub 2009 Oct 13.

19.

Amyloid precursor protein is required for convergent-extension movements during Zebrafish development.

Joshi P, Liang JO, DiMonte K, Sullivan J, Pimplikar SW.

Dev Biol. 2009 Nov 1;335(1):1-11. doi: 10.1016/j.ydbio.2009.07.041. Epub 2009 Aug 4.

20.

PAT1 induces cell death signal and SET mislocalization into the cytoplasm by increasing APP/APLP2 at the cell surface.

Briand S, Facchinetti P, Clamagirand C, Madeira A, Pommet JM, Pimplikar SW, Allinquant B.

Neurobiol Aging. 2011 Jun;32(6):1099-113. doi: 10.1016/j.neurobiolaging.2009.05.021. Epub 2009 Jun 30.

PMID:
19570594
21.

Reassessing the amyloid cascade hypothesis of Alzheimer's disease.

Pimplikar SW.

Int J Biochem Cell Biol. 2009 Jun;41(6):1261-8. doi: 10.1016/j.biocel.2008.12.015. Epub 2008 Dec 30. Review.

22.

Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease.

Varvel NH, Bhaskar K, Patil AR, Pimplikar SW, Herrup K, Lamb BT.

J Neurosci. 2008 Oct 22;28(43):10786-93. doi: 10.1523/JNEUROSCI.2441-08.2008.

23.

Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain.

Ryan KA, Pimplikar SW.

J Cell Biol. 2005 Oct 24;171(2):327-35. Epub 2005 Oct 17.

24.

Androgen receptor (AR) NH2- and COOH-terminal interactions result in the differential influences on the AR-mediated transactivation and cell growth.

Hsu CL, Chen YL, Ting HJ, Lin WJ, Yang Z, Zhang Y, Wang L, Wu CT, Chang HC, Yeh S, Pimplikar SW, Chang C.

Mol Endocrinol. 2005 Feb;19(2):350-61. Epub 2004 Oct 28.

PMID:
15514032
25.

Regulation of nuclear functions--nucleocytoplasmic transport in context.

Tartakoff AM, Matera AG, Pimplikar SW, Weimbs T.

Eur J Cell Biol. 2004 Jul;83(5):185-92. Review. No abstract available.

PMID:
15346808
27.

AbetaPP, apoptosis and Alzheimer's disease.

Pimplikar SW.

J Alzheimers Dis. 2002 Feb;4(1):39-40. No abstract available.

PMID:
12214017
28.

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus.

Gao Y, Pimplikar SW.

Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14979-84. Epub 2001 Dec 11.

29.

PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.

Zheng P, Eastman J, Vande Pol S, Pimplikar SW.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14745-50.

31.

Basolateral protein transport in streptolysin O-permeabilized MDCK cells.

Pimplikar SW, Ikonen E, Simons K.

J Cell Biol. 1994 Jun;125(5):1025-35.

32.

Regulation of apical transport in epithelial cells by a Gs class of heterotrimeric G protein.

Pimplikar SW, Simons K.

Nature. 1993 Apr 1;362(6419):456-8.

PMID:
8385268
33.

Role of heterotrimeric G proteins in polarized membrane transport.

Pimplikar SW, Simons K.

J Cell Sci Suppl. 1993;17:27-32. Review.

PMID:
8144702
34.

Sphingolipid transport from the trans-Golgi network to the apical surface in permeabilized MDCK cells.

Kobayashi T, Pimplikar SW, Parton RG, Bhakdi S, Simons K.

FEBS Lett. 1992 Apr 6;300(3):227-31.

36.

What the granins tell us about the formation of secretory granules in neuroendocrine cells.

Chanat E, Pimplikar SW, Stinchcombe JC, Huttner WB.

Cell Biophys. 1991 Oct-Dec;19(1-3):85-91. Review. No abstract available.

37.

Structure and function of the band 3 Cl-/HCO3- transporter.

Reithmeier RA, Lieberman DM, Casey JR, Pimplikar SW, Werner PK, See H, Pirraglia CA.

Ann N Y Acad Sci. 1989;574:75-83. No abstract available.

PMID:
2634358
38.
40.

Affinity chromatography of Band 3, the anion transport protein of erythrocyte membranes.

Pimplikar SW, Reithmeier RA.

J Biol Chem. 1986 Jul 25;261(21):9770-8.

41.

Analysis of erythrocyte membrane proteins from dystrophic hamsters.

Pimplikar SW, Malhotra SK.

FEBS Lett. 1983 May 30;156(1):141-4.

42.

Kidney, liver, erythrocyte membrane Na, K-adenosine triphosphatase in protein-energy malnourished rats.

Pimplikar SW, Kaplay SS.

Biochem Med. 1981 Aug;26(1):12-9. No abstract available.

PMID:
6271117
43.

Kidney, liver and erythrocyte membrane Na+-K+ adenosine triphosphatase in oral contraceptive treated rats.

Pimplikar SW, Ramanadham M, Kaplay SS.

Indian J Med Res. 1980 May;71:734-7. No abstract available.

PMID:
6250978

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