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Items: 12

1.

Discovery of CP-199,330 and CP-199,331: two potent and orally efficacious cysteinyl LT1 receptor antagonists devoid of liver toxicity.

Chambers RJ, Marfat A, Antognoli GW, Cheng JB, Damon DB, Kuperman AV, Liston TC, Mebus C, Pillar JS, Shirley JT, Watson JW.

Bioorg Med Chem Lett. 1999 Sep 20;9(18):2773-8.

PMID:
10509933
2.

Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists.

Chambers RJ, Antognoli GW, Cheng JB, Kuperman AV, Liston TC, Marfat A, Owens BS, Pillar JS, Shirley JT, Watson JW.

Bioorg Med Chem Lett. 1998 Dec 15;8(24):3577-82.

PMID:
9934474
3.

N-carbamoyl analogs of Zafirlukast: potent receptor antagonists of leukotriene D4.

Brown MF, Marfat A, Antognoli G, Chambers RJ, Cheng JB, Damon DB, Liston TE, McGlynn MA, O'Sullivan SP, Owens BS, Pillar JS, Shirley JT, Watson JW.

Bioorg Med Chem Lett. 1998 Sep 22;8(18):2451-6.

PMID:
9873560
4.

Development of new chromanol antagonists of leukotriene D4.

Chambers RJ, Antognoli GW, Cheng JB, Marfat A, Pillar JS, Shirley JT, Watson JW.

Bioorg Med Chem Lett. 1998 Jul 21;8(14):1791-6.

PMID:
9873435
5.

Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase.

Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB.

J Biol Chem. 1998 Jun 19;273(25):15559-64.

6.

Isolation and characterization of PDE8A, a novel human cAMP-specific phosphodiesterase.

Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB.

Biochem Biophys Res Commun. 1998 May 29;246(3):570-7.

PMID:
9618252
7.

Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.

Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.

Inflamm Res. 1997 May;46(5):168-79.

PMID:
9197987
8.

Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret.

Duplantier AJ, Biggers MS, Chambers RJ, Cheng JB, Cooper K, Damon DB, Eggler JF, Kraus KG, Marfat A, Masamune H, Pillar JS, Shirley JT, Umland JP, Watson JW.

J Med Chem. 1996 Jan 5;39(1):120-5.

PMID:
8568798
9.

Vortex flow filtration of mammalian and insect cells.

Hawrylik SJ, Wasilko DJ, Pillar JS, Cheng JB, Lee SE.

Cytotechnology. 1994;15(1-3):253-8.

PMID:
7765938
10.
11.

Evidence that peptidoleukotriene is a prerequisite for antigen-dependent thromboxane synthesis in IgG1-passively sensitized guinea pig lungs.

Cheng JB, Pillar JS, Conklyn MJ, Breslow R, Shirley JT, Showell HJ.

J Pharmacol Exp Ther. 1990 Nov;255(2):664-71.

PMID:
2243346

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