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Items: 1 to 50 of 95

1.

Risk prediction for severe disease and better diagnostic accuracy in early dengue infection; the Colombo dengue study.

Sigera PC, Amarasekara R, Rodrigo C, Rajapakse S, Weeratunga P, De Silva NL, Huang CH, Sahoo MK, Pinsky BA, Pillai DR, Tissera HA, Jayasinghe S, Handunnetti S, Fernando SD.

BMC Infect Dis. 2019 Aug 1;19(1):680. doi: 10.1186/s12879-019-4304-9.

2.

Multicenter Clinical Validation of the Molecular BD Max Enteric Viral Panel for Detection of Enteric Pathogens.

Stokes W, Simner PJ, Mortensen J, Oethinger M, Stellrecht K, Lockamy E, Lay T, Bouchy P, Pillai DR.

J Clin Microbiol. 2019 Aug 26;57(9). pii: e00306-19. doi: 10.1128/JCM.00306-19. Print 2019 Sep.

3.

The Impact of Malaria on Liver Enzymes: A Retrospective Cohort Study (2010-2017).

Cheaveau J, Marasinghe D, Akakpo S, Deardon R, Naugler C, Chin A, Pillai DR.

Open Forum Infect Dis. 2019 May 16;6(6):ofz234. doi: 10.1093/ofid/ofz234. eCollection 2019 Jun.

4.

Reply to Awandu, et al.

Golassa L, Cheaveau J, Mohon AN, Pillai DR.

Clin Infect Dis. 2019 Feb 15. pii: ciz148. doi: 10.1093/cid/ciz148. [Epub ahead of print] No abstract available.

PMID:
30763414
5.

Prevalence and Epidemiological Characteristics of Asymptomatic Malaria Based on Ultrasensitive Diagnostics: A Cross-sectional Study.

Girma S, Cheaveau J, Mohon AN, Marasinghe D, Legese R, Balasingam N, Abera A, Feleke SM, Golassa L, Pillai DR.

Clin Infect Dis. 2019 Aug 30;69(6):1003-1010. doi: 10.1093/cid/ciy1005.

PMID:
30475992
6.

Clinical Validation of a Commercial LAMP Test for Ruling out Malaria in Returning Travelers: A Prospective Diagnostic Trial.

Cheaveau J, Nguyen H, Chow B, Marasinghe D, Mohon AN, Yuan H, Viana G, van Schalkwyk D, Church D, Chan W, Pillai DR.

Open Forum Infect Dis. 2018 Oct 12;5(11):ofy260. doi: 10.1093/ofid/ofy260. eCollection 2018 Nov.

7.

Epidemiological and genomic characterization of community-acquired Clostridium difficile infections.

Thornton CS, Rubin JE, Greninger AL, Peirano G, Chiu CY, Pillai DR.

BMC Infect Dis. 2018 Aug 31;18(1):443. doi: 10.1186/s12879-018-3337-9.

8.

Molecular detection of Enteropathogens from diarrheic stool of HIV positive patients in Gondar, Ethiopia.

Seid L, Stokes W, Bayih AG, Getie S, Abere A, Tesfa H, Pillai DR.

BMC Infect Dis. 2018 Jul 31;18(1):354. doi: 10.1186/s12879-018-3265-8.

9.

A Novel Single-Nucleotide Polymorphism Loop Mediated Isothermal Amplification Assay for Detection of Artemisinin-Resistant Plasmodium falciparum Malaria.

Mohon AN, Menard D, Alam MS, Perera K, Pillai DR.

Open Forum Infect Dis. 2018 Jan 9;5(4):ofy011. doi: 10.1093/ofid/ofy011. eCollection 2018 Apr.

10.

Laboratory Diagnosis of Parasites from the Gastrointestinal Tract.

Garcia LS, Arrowood M, Kokoskin E, Paltridge GP, Pillai DR, Procop GW, Ryan N, Shimizu RY, Visvesvara G.

Clin Microbiol Rev. 2017 Nov 15;31(1). pii: e00025-17. doi: 10.1128/CMR.00025-17. Print 2018 Jan. Review.

11.

Multisite Evaluation of the BD Max Extended Enteric Bacterial Panel for Detection of Yersinia enterocolitica, Enterotoxigenic Escherichia coli, Vibrio, and Plesiomonas shigelloides from Stool Specimens.

Simner PJ, Oethinger M, Stellrecht KA, Pillai DR, Yogev R, Leblond H, Mortensen J.

J Clin Microbiol. 2017 Nov;55(11):3258-3266. doi: 10.1128/JCM.00911-17. Epub 2017 Sep 6.

12.

Detection of Plasmodium Infection by the illumigene Malaria Assay Compared to Reference Microscopy and Real-Time PCR.

Rypien C, Chow B, Chan WW, Church DL, Pillai DR.

J Clin Microbiol. 2017 Oct;55(10):3037-3045. doi: 10.1128/JCM.00806-17. Epub 2017 Aug 2.

13.

Susceptibility Testing of Medically Important Parasites.

Genetu Bayih A, Debnath A, Mitre E, Huston CD, Laleu B, Leroy D, Blasco B, Campo B, Wells TNC, Willis PA, Sjö P, Van Voorhis WC, Pillai DR.

Clin Microbiol Rev. 2017 Jul;30(3):647-669. doi: 10.1128/CMR.00111-16. Review.

14.

Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors.

Michalski D, Pitsch R, Pillai DR, Mages B, Aleithe S, Grosche J, Martens H, Schlachetzki F, Härtig W.

PLoS One. 2017 Apr 26;12(4):e0174996. doi: 10.1371/journal.pone.0174996. eCollection 2017.

15.

Performance of loop-mediated isothermal amplification (LAMP) for the diagnosis of malaria among malaria suspected pregnant women in Northwest Ethiopia.

Tegegne B, Getie S, Lemma W, Mohon AN, Pillai DR.

Malar J. 2017 Jan 19;16(1):34. doi: 10.1186/s12936-017-1692-4.

16.
17.

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Ménard D, Khim N, Beghain J, Adegnika AA, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos MD, Cao J, Chen JH, Collet L, Cui L, Thakur GD, Dieye A, Djallé D, Dorkenoo MA, Eboumbou-Moukoko CE, Espino FE, Fandeur T, Ferreira-da-Cruz MF, Fola AA, Fuehrer HP, Hassan AM, Herrera S, Hongvanthong B, Houzé S, Ibrahim ML, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner PG, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati JB, Ménard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niaré K, Noedl H, Ouédraogo JB, Pillai DR, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silué KD, Sirima SB, Sutherland C, Syafruddin D, Tahar R, Tang LH, Touré OA, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale JC, Stokes B, Straimer J, Witkowski B, Fidock DA, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O; KARMA Consortium.

N Engl J Med. 2016 Jun 23;374(25):2453-64. doi: 10.1056/NEJMoa1513137.

18.

NINA-LAMP compared to microscopy, RDT, and nested PCR for the detection of imported malaria.

Mohon AN, Lee LD, Bayih AG, Folefoc A, Guelig D, Burton RA, LaBarre P, Chan W, Meatherall B, Pillai DR.

Diagn Microbiol Infect Dis. 2016 Jun;85(2):149-53. doi: 10.1016/j.diagmicrobio.2015.11.009. Epub 2015 Nov 10.

19.

Whole-Genome Sequencing Reveals the Origin and Rapid Evolution of an Emerging Outbreak Strain of Streptococcus pneumoniae 12F.

Deng X, Peirano G, Schillberg E, Mazzulli T, Gray-Owen SD, Wylie JL, Robinson DA, Mahmud SM, Pillai DR.

Clin Infect Dis. 2016 May 1;62(9):1126-1132. doi: 10.1093/cid/ciw050. Epub 2016 Feb 7.

PMID:
26908785
20.

Development and validation of a Pneumocystis jirovecii real-time polymerase chain reaction assay for diagnosis of Pneumocystis pneumonia.

Church DL, Ambasta A, Wilmer A, Williscroft H, Ritchie G, Pillai DR, Champagne S, Gregson DG.

Can J Infect Dis Med Microbiol. 2015 Sep-Oct;26(5):263-7.

21.

A Unique Plasmodium falciparum K13 Gene Mutation in Northwest Ethiopia.

Bayih AG, Getnet G, Alemu A, Getie S, Mohon AN, Pillai DR.

Am J Trop Med Hyg. 2016 Jan;94(1):132-5. doi: 10.4269/ajtmh.15-0477. Epub 2015 Oct 19.

22.

Assay for drug discovery: Synthesis and testing of nitrocefin analogues for use as β-lactamase substrates.

Ghavami A, Labbé G, Brem J, Goodfellow VJ, Marrone L, Tanner CA, King DT, Lam M, Strynadka NC, Pillai DR, Siemann S, Spencer J, Schofield CJ, Dmitrienko GI.

Anal Biochem. 2015 Oct 1;486:75-7. doi: 10.1016/j.ab.2015.06.032. Epub 2015 Jul 2.

PMID:
26142222
23.

Heat shock protein 90 inhibitors repurposed against Entamoeba histolytica.

Shahinas D, Debnath A, Benedict C, McKerrow JH, Pillai DR.

Front Microbiol. 2015 Apr 28;6:368. doi: 10.3389/fmicb.2015.00368. eCollection 2015.

24.

Genetic analysis of invasive pneumococcal isolates from children in Ontario, Canada, 2007-2012.

Deng X, Arya G, Memari N, Mackenzie R, MacMullin G, Low DE, Pillai DR, Gubbay JB.

Pediatr Infect Dis J. 2015 Jun;34(6):594-8. doi: 10.1097/INF.0000000000000697.

PMID:
25831418
25.

Multicenter evaluation of the BD max enteric bacterial panel PCR assay for rapid detection of Salmonella spp., Shigella spp., Campylobacter spp. (C. jejuni and C. coli), and Shiga toxin 1 and 2 genes.

Harrington SM, Buchan BW, Doern C, Fader R, Ferraro MJ, Pillai DR, Rychert J, Doyle L, Lainesse A, Karchmer T, Mortensen JE.

J Clin Microbiol. 2015 May;53(5):1639-47. doi: 10.1128/JCM.03480-14. Epub 2015 Mar 4.

26.

Evaluation of non-instrumented nucleic acid amplification by loop-mediated isothermal amplification (NINA-LAMP) for the diagnosis of malaria in Northwest Ethiopia.

Sema M, Alemu A, Bayih AG, Getie S, Getnet G, Guelig D, Burton R, LaBarre P, Pillai DR.

Malar J. 2015 Jan 28;14:44. doi: 10.1186/s12936-015-0559-9.

27.

Mutations in Plasmodium falciparum K13 propeller gene from Bangladesh (2009-2013).

Mohon AN, Alam MS, Bayih AG, Folefoc A, Shahinas D, Haque R, Pillai DR.

Malar J. 2014 Nov 18;13:431. doi: 10.1186/1475-2875-13-431.

28.

False positive malaria rapid diagnostic test in returning traveler with typhoid fever.

Meatherall B, Preston K, Pillai DR.

BMC Infect Dis. 2014 Jul 9;14:377. doi: 10.1186/1471-2334-14-377.

29.

Mouse studies on inhibitors of Plasmodium falciparum Hsp90: progress and challenges.

Bayih AG, Pillai DR.

Parasitology. 2014 Aug;141(9):1216-22. doi: 10.1017/S0031182014000754. Epub 2014 May 28. Review.

PMID:
24871961
30.

Outbreak of invasive Streptococcus pneumoniae serotype 12F among a marginalized inner-city population in Winnipeg, Canada, 2009-2011.

Schillberg E, Isaac M, Deng X, Peirano G, Wylie JL, Van Caeseele P, Pillai DR, Sinnock H, Mahmud SM.

Clin Infect Dis. 2014 Sep 1;59(5):651-7. doi: 10.1093/cid/ciu366. Epub 2014 May 19.

PMID:
24842908
31.

Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.

Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH.

Antimicrob Agents Chemother. 2014 Jul;58(7):4138-44. doi: 10.1128/AAC.02576-14. Epub 2014 May 12.

32.

Artemisinin combination therapy can result in clinical failure if oral therapy is not directly observed.

Chan WW, Virmani D, Pillai DR.

Can J Infect Dis Med Microbiol. 2013 Winter;24(4):215-6.

33.

Characterizing cerebral oxygen metabolism employing oxygen-17 MRI/MRS at high fields.

Gordji-Nejad A, Möllenhoff K, Oros-Peusquens AM, Pillai DR, Shah NJ.

MAGMA. 2014 Feb;27(1):81-93. doi: 10.1007/s10334-013-0413-4. Epub 2013 Dec 15. Review.

PMID:
24337392
34.

Spatiotemporal dynamics and demographic profiles of imported Plasmodium falciparum and Plasmodium vivax infections in Ontario, Canada (1990-2009).

Nelder MP, Russell C, Williams D, Johnson K, Li L, Baker SL, Marshall S, Bhanich-Supapol W, Pillai DR, Ralevski F.

PLoS One. 2013 Sep 30;8(9):e76208. doi: 10.1371/journal.pone.0076208. eCollection 2013.

35.

A purine analog synergizes with chloroquine (CQ) by targeting Plasmodium falciparum Hsp90 (PfHsp90).

Shahinas D, Folefoc A, Taldone T, Chiosis G, Crandall I, Pillai DR.

PLoS One. 2013 Sep 30;8(9):e75446. doi: 10.1371/journal.pone.0075446. eCollection 2013.

36.

Streptococcus pneumoniae infection: a Canadian perspective.

Deng X, Church D, Vanderkooi OG, Low DE, Pillai DR.

Expert Rev Anti Infect Ther. 2013 Aug;11(8):781-91. doi: 10.1586/14787210.2013.814831. Review.

PMID:
23977934
37.

Indeterminate tcdB using a Clostridium difficile PCR assay: a retrospective cohort study.

Leis JA, Gold WL, Ng J, Hirji Z, Pillai DR, Broukhanski G, Raggiunti P, Hota S, McGeer A, Poutanen SM.

BMC Infect Dis. 2013 Jul 16;13:324. doi: 10.1186/1471-2334-13-324.

38.

Comparative Genomic Analyses of Streptococcus pseudopneumoniae Provide Insight into Virulence and Commensalism Dynamics.

Shahinas D, Thornton CS, Tamber GS, Arya G, Wong A, Jamieson FB, Ma JH, Alexander DC, Low DE, Pillai DR.

PLoS One. 2013 Jun 19;8(6):e65670. doi: 10.1371/journal.pone.0065670. Print 2013.

39.

Population-based laboratory surveillance of imported malaria in metropolitan Calgary, 2000-2011.

Lee CS, Gregson DB, Church D, Laupland KB, Eckhardt R, Ross T, Chan W, Pillai DR.

PLoS One. 2013 Apr 15;8(4):e60751. doi: 10.1371/journal.pone.0060751. Print 2013.

40.

Have changing pneumococcal vaccination programmes impacted disease in Ontario?

Lim GH, Wormsbecker AE, McGeer A, Pillai DR, Gubbay JB, Rudnick W, Low DE, Green K, Crowcroft NS, Deeks SL.

Vaccine. 2013 May 31;31(24):2680-5. doi: 10.1016/j.vaccine.2013.04.007. Epub 2013 Apr 16.

PMID:
23597716
41.

A potential new tool for managing Clostridium difficile infection.

Armstrong GD, Pillai DR, Louie TJ, MacDonald JA, Beck PL.

J Infect Dis. 2013 May 15;207(10):1484-6. doi: 10.1093/infdis/jit069. Epub 2013 Feb 18. No abstract available.

PMID:
23420904
42.

Neurovascular protection by targeting early blood-brain barrier disruption with neurotrophic factors after ischemia-reperfusion in rats*.

Pillai DR, Shanbhag NC, Dittmar MS, Bogdahn U, Schlachetzki F.

J Cereb Blood Flow Metab. 2013 Apr;33(4):557-66. doi: 10.1038/jcbfm.2012.201. Epub 2013 Jan 9.

43.

Targeting Plasmodium falciparum Hsp90: Towards Reversing Antimalarial Resistance.

Shahinas D, Folefoc A, Pillai DR.

Pathogens. 2013 Feb 4;2(1):33-54. doi: 10.3390/pathogens2010033. Review.

44.

Real-time polymerase chain reaction method for detection of toxigenic Clostridium difficile from stools and presumptive identification of NAP1 clone.

Jayaratne PA, Monkman L, Broukhanski G, Pillai DR, Lee C.

Diagn Microbiol Infect Dis. 2013 Feb;75(2):121-3. doi: 10.1016/j.diagmicrobio.2012.10.002. Epub 2012 Nov 20.

PMID:
23182075
45.

Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing.

Shahinas D, Silverman M, Sittler T, Chiu C, Kim P, Allen-Vercoe E, Weese S, Wong A, Low DE, Pillai DR.

MBio. 2012 Oct 23;3(5). pii: e00338-12. doi: 10.1128/mBio.00338-12.

46.

Chloroquine-resistant malaria in travelers returning from Haiti after 2010 earthquake.

Gharbi M, Pillai DR, Lau R, Hubert V, Khairnar K, Existe A, Kendjo E, Dahlström S, Guérin PJ, Le Bras J; French National Reference Center for Imported Malaria Study.

Emerg Infect Dis. 2012 Aug;18(8):1346-9. doi: 10.3201/eid1808.111779.

47.

Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.

Shahinas D, Macmullin G, Benedict C, Crandall I, Pillai DR.

Antimicrob Agents Chemother. 2012 Aug;56(8):4207-13. doi: 10.1128/AAC.00328-12. Epub 2012 May 21.

48.

Host immune response in returning travellers infected with malaria.

MacMullin G, Mackenzie R, Lau R, Khang J, Zhang H, Rajwans N, Liles WC, Pillai DR.

Malar J. 2012 May 3;11:148.

49.

Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections.

Pillai DR, Lau R, Khairnar K, Lepore R, Via A, Staines HM, Krishna S.

Malar J. 2012 Apr 27;11:131. doi: 10.1186/1475-2875-11-131.

50.

A spatial analysis of individual- and neighborhood-level determinants of malaria incidence in adults, Ontario, Canada.

Eckhardt R, Berrang-Ford L, Ross NA, Pillai DR, Buckeridge DL.

Emerg Infect Dis. 2012 May;18(5):775-82. doi: 10.3201/eid1805.110602.

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