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The cellular prion protein controls the mesenchymal-like molecular subtype and predicts disease outcome in colorectal cancer.

Le Corre D, Ghazi A, Balogoun R, Pilati C, Aparicio T, Martin-Lannerée S, Marisa L, Djouadi F, Poindessous V, Crozet C, Emile JF, Mulot C, Le Malicot K, Boige V, Blons H, de Reynies A, Taieb J, Ghiringhelli F, Bennouna J, Launay JM, Laurent-Puig P, Mouillet-Richard S.

EBioMedicine. 2019 Aug;46:94-104. doi: 10.1016/j.ebiom.2019.07.036. Epub 2019 Jul 31.


Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis.

Lawlor RT, Veronese N, Pea A, Nottegar A, Smith L, Pilati C, Demurtas J, Fassan M, Cheng L, Luchini C.

BMC Cancer. 2019 Mar 14;19(1):232. doi: 10.1186/s12885-019-5424-8.


Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis.

Luchini C, Veronese N, Nottegar A, Riva G, Pilati C, Mafficini A, Stubbs B, Simbolo M, Mombello A, Corbo V, Cheng L, Yachida S, Wood LD, Lawlor RT, Salvia R, Scarpa A.

Pancreas. 2019 Jan;48(1):70-76. doi: 10.1097/MPA.0000000000001194.


Histo-molecular oncogenesis of pancreatic cancer: From precancerous lesions to invasive ductal adenocarcinoma.

Riva G, Pea A, Pilati C, Fiadone G, Lawlor RT, Scarpa A, Luchini C.

World J Gastrointest Oncol. 2018 Oct 15;10(10):317-327. doi: 10.4251/wjgo.v10.i10.317. Review.


Unresectable metastatic colorectal cancer patient cured with cetuximab-based chemotherapy: a case report with new molecular insights.

Cohen R, Sroussi M, Pilati C, Houry S, Laurent-Puig P, André T.

J Gastrointest Oncol. 2018 Aug;9(4):E23-E27. doi: 10.21037/jgo.2018.05.10.


CD200 expression is a feature of solid pseudopapillary neoplasms of the pancreas.

Lawlor RT, Daprà V, Girolami I, Pea A, Pilati C, Nottegar A, Piccoli P, Parolini C, Sperandio N, Capelli P, Scarpa A, Luchini C.

Virchows Arch. 2019 Jan;474(1):105-109. doi: 10.1007/s00428-018-2437-7. Epub 2018 Aug 21.


PD-1, PD-L1, and CD163 in pancreatic undifferentiated carcinoma with osteoclast-like giant cells: expression patterns and clinical implications.

Luchini C, Cros J, Pea A, Pilati C, Veronese N, Rusev B, Capelli P, Mafficini A, Nottegar A, Brosens LAA, Noë M, Offerhaus GJA, Chianchiano P, Riva G, Piccoli P, Parolini C, Malleo G, Lawlor RT, Corbo V, Sperandio N, Barbareschi M, Fassan M, Cheng L, Wood LD, Scarpa A.

Hum Pathol. 2018 Nov;81:157-165. doi: 10.1016/j.humpath.2018.07.006. Epub 2018 Jul 18.


Extranodal extension of nodal metastases is a poor prognostic moderator in non-small cell lung cancer: a meta-analysis.

Luchini C, Veronese N, Nottegar A, Cheng M, Kaneko T, Pilati C, Tabbò F, Stubbs B, Pea A, Bagante F, Demurtas J, Fassan M, Infante M, Cheng L, Scarpa A.

Virchows Arch. 2018 Jun;472(6):939-947. doi: 10.1007/s00428-018-2309-1. Epub 2018 Feb 1. Review.


CDX2 prognostic value in stage II/III resected colon cancer is related to CMS classification.

Pilati C, Taieb J, Balogoun R, Marisa L, de Reyniès A, Laurent-Puig P.

Ann Oncol. 2017 May 1;28(5):1032-1035. doi: 10.1093/annonc/mdx066.


Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.

Pilati C, Shinde J, Alexandrov LB, Assié G, André T, Hélias-Rodzewicz Z, Ducoudray R, Le Corre D, Zucman-Rossi J, Emile JF, Bertherat J, Letouzé E, Laurent-Puig P.

J Pathol. 2017 May;242(1):10-15. doi: 10.1002/path.4880. Epub 2017 Mar 29.


Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.

Nault JC, Couchy G, Balabaud C, Morcrette G, Caruso S, Blanc JF, Bacq Y, Calderaro J, Paradis V, Ramos J, Scoazec JY, Gnemmi V, Sturm N, Guettier C, Fabre M, Savier E, Chiche L, Labrune P, Selves J, Wendum D, Pilati C, Laurent A, De Muret A, Le Bail B, Rebouissou S, Imbeaud S; GENTHEP Investigators, Bioulac-Sage P, Letouzé E, Zucman-Rossi J.

Gastroenterology. 2017 Mar;152(4):880-894.e6. doi: 10.1053/j.gastro.2016.11.042. Epub 2016 Dec 7.


Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases.

Padovani D, Hessani A, Castillo FT, Liot G, Andriamihaja M, Lan A, Pilati C, Blachier F, Sen S, Galardon E, Artaud I.

Nat Commun. 2016 Nov 16;7:13386. doi: 10.1038/ncomms13386.


A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer.

Salvucci M, Würstle ML, Morgan C, Curry S, Cremona M, Lindner AU, Bacon O, Resler AJ, Murphy ÁC, O'Byrne R, Flanagan L, Dasgupta S, Rice N, Pilati C, Zink E, Schöller LM, Toomey S, Lawler M, Johnston PG, Wilson R, Camilleri-Broët S, Salto-Tellez M, McNamara DA, Kay EW, Laurent-Puig P, Van Schaeybroeck S, Hennessy BT, Longley DB, Rehm M, Prehn JH.

Clin Cancer Res. 2017 Mar 1;23(5):1200-1212. doi: 10.1158/1078-0432.CCR-16-1084. Epub 2016 Sep 20.


Illusion of arm movement evoked by tendon vibration in patients with spinal cord injury.

Fusco G, Tidoni E, Barone N, Pilati C, Aglioti SM.

Restor Neurol Neurosci. 2016 Sep 21;34(5):815-26. doi: 10.3233/RNN-160660.


Genotype-phenotype correlation of CTNNB1 mutations reveals different ß-catenin activity associated with liver tumor progression.

Rebouissou S, Franconi A, Calderaro J, Letouzé E, Imbeaud S, Pilati C, Nault JC, Couchy G, Laurent A, Balabaud C, Bioulac-Sage P, Zucman-Rossi J.

Hepatology. 2016 Dec;64(6):2047-2061. doi: 10.1002/hep.28638. Epub 2016 Jun 11.


Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV.

Nault JC, Mami I, La Bella T, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J.

Mol Ther. 2016 Apr;24(4):660-1. doi: 10.1038/mt.2016.47. No abstract available.


Immune and Stromal Classification of Colorectal Cancer Is Associated with Molecular Subtypes and Relevant for Precision Immunotherapy.

Becht E, de Reyniès A, Giraldo NA, Pilati C, Buttard B, Lacroix L, Selves J, Sautès-Fridman C, Laurent-Puig P, Fridman WH.

Clin Cancer Res. 2016 Aug 15;22(16):4057-66. doi: 10.1158/1078-0432.CCR-15-2879. Epub 2016 Mar 18.


AAV2 and Hepatocellular Carcinoma.

Nault JC, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J.

Hum Gene Ther. 2016 Mar;27(3):211-3. doi: 10.1089/hum.2016.002. No abstract available.


Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas.

Nault JC, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J.

Nat Genet. 2015 Oct;47(10):1187-93. doi: 10.1038/ng.3389. Epub 2015 Aug 24.


Mutations leading to constitutive active gp130/JAK1/STAT3 pathway.

Pilati C, Zucman-Rossi J.

Cytokine Growth Factor Rev. 2015 Oct;26(5):499-506. doi: 10.1016/j.cytogfr.2015.07.010. Epub 2015 Jul 3. Review.


Expression of pEGFR and pAKT as response-predictive biomarkers for RAS wild-type patients to anti-EGFR monoclonal antibodies in metastatic colorectal cancers.

Harlé A, Salleron J, Perkins G, Pilati C, Blons H, Laurent-Puig P, Merlin JL.

Br J Cancer. 2015 Aug 11;113(4):680-5. doi: 10.1038/bjc.2015.250. Epub 2015 Jul 14.


Natural Infection of the Wild Canid Lycalopex gymnocercus by the Protozoan Rangelia vitalii, the Agent of Canine Rangeliosis.

de Quadros RM, Soares JF, Xavier JS, Pilati C, da Costa JL, Miotto BA, Miletti LC, Labruna MB.

J Wildl Dis. 2015 Jul;51(3):787-9. doi: 10.7589/2014-08-194. Epub 2015 May 1.


A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy.

Saridaki Z, Weidhaas JB, Lenz HJ, Laurent-Puig P, Jacobs B, De Schutter J, De Roock W, Salzman DW, Zhang W, Yang D, Pilati C, Bouché O, Piessevaux H, Tejpar S.

Clin Cancer Res. 2014 Sep 1;20(17):4499-4510. doi: 10.1158/1078-0432.CCR-14-0348.


Beyond KRAS status and response to anti-EGFR therapy in metastatic colorectal cancer.

Perkins G, Pilati C, Blons H, Laurent-Puig P.

Pharmacogenomics. 2014 May;15(7):1043-52. doi: 10.2217/pgs.14.66. Review.


Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation.

Pilati C, Letouzé E, Nault JC, Imbeaud S, Boulai A, Calderaro J, Poussin K, Franconi A, Couchy G, Morcrette G, Mallet M, Taouji S, Balabaud C, Terris B, Canal F, Paradis V, Scoazec JY, de Muret A, Guettier C, Bioulac-Sage P, Chevet E, Calvo F, Zucman-Rossi J.

Cancer Cell. 2014 Apr 14;25(4):428-41. doi: 10.1016/j.ccr.2014.03.005.


Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma.

Poussin K, Pilati C, Couchy G, Calderaro J, Bioulac-Sage P, Bacq Y, Paradis V, Leteurtre E, Sturm N, Ramos J, Guettier C, Bardier-Dupas A, Boulai A, Wendum D, Selves J, Izard T, Nault JC, Zucman-Rossi J.

Oncoimmunology. 2013 Dec 1;2(12):e27090. Epub 2014 Jan 3.


High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.

Nault JC, Mallet M, Pilati C, Calderaro J, Bioulac-Sage P, Laurent C, Laurent A, Cherqui D, Balabaud C, Zucman-Rossi J.

Nat Commun. 2013;4:2218. doi: 10.1038/ncomms3218. Erratum in: Nat Commun. 2013;4:2577. Zucman Rossi, Jessica [corrected to Zucman-Rossi, Jessica].


STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model.

Couronné L, Scourzic L, Pilati C, Della Valle V, Duffourd Y, Solary E, Vainchenker W, Merlio JP, Beylot-Barry M, Damm F, Stern MH, Gaulard P, Lamant L, Delabesse E, Merle-Beral H, Nguyen-Khac F, Fontenay M, Tilly H, Bastard C, Zucman-Rossi J, Bernard OA, Mercher T.

Haematologica. 2013 Nov;98(11):1748-52. doi: 10.3324/haematol.2013.085068. Epub 2013 Jul 19.


Evaluation of biochemical, hematological and oxidative parameters in mice exposed to the herbicide glyphosate-Roundup(®).

Jasper R, Locatelli GO, Pilati C, Locatelli C.

Interdiscip Toxicol. 2012 Sep;5(3):133-40. doi: 10.2478/v10102-012-0022-5.


Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox.

Cordova FM, Aguiar AS Jr, Peres TV, Lopes MW, Gonçalves FM, Pedro DZ, Lopes SC, Pilati C, Prediger RD, Farina M, Erikson KM, Aschner M, Leal RB.

Arch Toxicol. 2013 Jul;87(7):1231-44. doi: 10.1007/s00204-013-1017-5. Epub 2013 Feb 6.


Asymptomatic cattle naturally infected with Mycobacterium bovis present exacerbated tissue pathology and bacterial dissemination.

Menin Á, Fleith R, Reck C, Marlow M, Fernandes P, Pilati C, Báfica A.

PLoS One. 2013;8(1):e53884. doi: 10.1371/journal.pone.0053884. Epub 2013 Jan 9.


In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function.

Cordova FM, Aguiar AS Jr, Peres TV, Lopes MW, Gonçalves FM, Remor AP, Lopes SC, Pilati C, Latini AS, Prediger RD, Erikson KM, Aschner M, Leal RB.

PLoS One. 2012;7(3):e33057. doi: 10.1371/journal.pone.0033057. Epub 2012 Mar 13.


GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation.

Nault JC, Fabre M, Couchy G, Pilati C, Jeannot E, Tran Van Nhieu J, Saint-Paul MC, De Muret A, Redon MJ, Buffet C, Salenave S, Balabaud C, Prevot S, Labrune P, Bioulac-Sage P, Scoazec JY, Chanson P, Zucman-Rossi J.

J Hepatol. 2012 Jan;56(1):184-91. doi: 10.1016/j.jhep.2011.07.018. Epub 2011 Aug 9.


Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas.

Pilati C, Amessou M, Bihl MP, Balabaud C, Nhieu JT, Paradis V, Nault JC, Izard T, Bioulac-Sage P, Couchy G, Poussin K, Zucman-Rossi J.

J Exp Med. 2011 Jul 4;208(7):1359-66. doi: 10.1084/jem.20110283. Epub 2011 Jun 20.


Italian version of Qualiveen-30: cultural adaptation of a neurogenic urinary disorder-specific instrument.

Bonniaud V, Bryant D, Pilati C, Menarini M, Lamartina M, Guyatt G, Del Popolo G.

Neurourol Urodyn. 2011 Mar;30(3):354-9. doi: 10.1002/nau.20967. Epub 2011 Feb 8.


Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model.

Locatelli C, Carvalho DR, Mascarello A, de Cordova CA, Yunes RA, Nunes RJ, Pilati C, Creczynski-Pasa TB.

Invest New Drugs. 2012 Jun;30(3):870-9. doi: 10.1007/s10637-010-9628-7. Epub 2011 Jan 8.


Capillaria hepatica in Puma concolor: first report in Brazil.

Quadros RM, Pilati C, Marques SM, Mazzolli M, Benedet RC.

J Zoo Wildl Med. 2009 Sep;40(3):586-7.


Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure.

Maron MB, Luther DJ, Pilati CF, Ohanyan V, Li T, Koshy S, Horne WI, Meszaros JG, Walro JM, Folkesson HG.

Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L487-95. doi: 10.1152/ajplung.90629.2008. Epub 2009 Jul 10.


Presence of Fasciola hepatica in feral nutria (Myocastor coypus) living in a public park in Brazil.

El-Kouba MM, Marques SM, Pilati C, Hamann W.

J Zoo Wildl Med. 2009 Mar;40(1):103-6.


Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours.

Rebouissou S, Amessou M, Couchy G, Poussin K, Imbeaud S, Pilati C, Izard T, Balabaud C, Bioulac-Sage P, Zucman-Rossi J.

Nature. 2009 Jan 8;457(7226):200-4. doi: 10.1038/nature07475. Epub 2008 Nov 19.


Treatment of neurogenic bowel dysfunction using transanal irrigation: a multicenter Italian study.

Del Popolo G, Mosiello G, Pilati C, Lamartina M, Battaglino F, Buffa P, Redaelli T, Lamberti G, Menarini M, Di Benedetto P, De Gennaro M.

Spinal Cord. 2008 Jul;46(7):517-22. doi: 10.1038/ Epub 2008 Mar 4.


Type VI collagen induces cardiac myofibroblast differentiation: implications for postinfarction remodeling.

Naugle JE, Olson ER, Zhang X, Mase SE, Pilati CF, Maron MB, Folkesson HG, Horne WI, Doane KJ, Meszaros JG.

Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H323-30. Epub 2005 Sep 2.


Mammomonogamus laryngeus (Railliet, 1899) infection in buffaloes in Rio Grande do Sul, Brazil.

Marques SM, Quadros RM, Pilati C.

Vet Parasitol. 2005 Jun 30;130(3-4):241-3.


Methamphetamine-gonadal steroid hormonal interactions: effects upon acute toxicity and striatal dopamine concentrations.

Dluzen DE, Anderson LI, Pilati CF.

Neurotoxicol Teratol. 2002 Mar-Apr;24(2):267-73.


Effect of massive sympathetic nervous system activation on coronary blood flow and myocardial energy pool.

Smith JM, Pilati CF.

Exp Biol Med (Maywood). 2002 Feb;227(2):125-32.


Clinical, pathological and antigenic aspects of bovine viral diarrhea virus (BVDV) type 2 isolates identified in Brazil.

Flores EF, Gil LH, Botton SA, Weiblen R, Ridpath JF, Kreutz LC, Pilati C, Driemeyer D, Moojen V, Wendelstein AC.

Vet Microbiol. 2000 Nov 15;77(1-2):175-83.


Role of angiotensin II in sympathetic nervous system induced left ventricular dysfunction.

Bosso FJ, Jarjoura DG, Pilati CF.

Can J Physiol Pharmacol. 1999 Oct;77(10):806-12.


Time-dependent changes in norepinephrine-induced left ventricular dysfunction and histopathologic condition.

Allman FD, Herold W, Bosso FJ, Pilati CF.

J Heart Lung Transplant. 1998 Oct;17(10):991-7.


Role of EDRF in the cardiopulmonary dysfunction produced by massive sympathetic activation.

Pilati CF, Maron MB, Bosso FJ.

J Appl Physiol (1985). 1995 May;78(5):1642-50.


Temporal changes in left ventricular function after massive sympathetic nervous system activation.

Lang SA, Maron MB, Bosso FJ, Pilati CF.

Can J Physiol Pharmacol. 1994 Jun;72(6):693-700.


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