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Items: 1 to 50 of 255

1.

The effect of vitamin D pathway genes and deferasirox pharmacogenetics on liver iron in thalassaemia major patients.

Allegra S, Cusato J, De Francia S, Longo F, Pirro E, Massano D, Avataneo V, De Nicolò A, Piga A, D'Avolio A.

Pharmacogenomics J. 2019 Jan 17. doi: 10.1038/s41397-019-0071-7. [Epub ahead of print]

PMID:
30651574
2.

Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with beta-thalassemia.

Piga A, Perrotta S, Gamberini MR, Voskaridou E, Melpignano A, Filosa A, Caruso V, Pietrangelo A, Longo F, Tartaglione I, Borgna-Pignatti C, Zhang X, Laadem A, Sherman ML, Attie KM.

Blood. 2019 Jan 7. pii: blood-2018-10-879247. doi: 10.1182/blood-2018-10-879247. [Epub ahead of print]

PMID:
30617198
3.

Atrial fibrillation in β-thalassemia Major Patients: Diagnosis, Management and Therapeutic Options.

Barbero U, Fornari F, Guarguagli S, Gaglioti CM, Longo F, Doronzo B, Anselmino M, Piga A.

Hemoglobin. 2018 May;42(3):189-193. doi: 10.1080/03630269.2018.1488724. Epub 2018 Oct 1. Review.

PMID:
30270686
4.

From ancient to old and modern durum wheat varieties: interaction among cultivar traits, management, and technological quality.

Mefleh M, Conte P, Fadda C, Giunta F, Piga A, Hassoun G, Motzo R.

J Sci Food Agric. 2018 Sep 28. doi: 10.1002/jsfa.9388. [Epub ahead of print] Review.

PMID:
30267406
5.

Role of CYP1A1, ABCG2, CYP24A1 and VDR gene polymorphisms on the evaluation of cardiac iron overload in thalassaemia patients.

Allegra S, Cusato J, De Francia S, Longo F, Pirro E, Massano D, Avataneo V, De Nicolò A, Piga A, D'Avolio A.

Pharmacogenet Genomics. 2018 Sep;28(9):199-206. doi: 10.1097/FPC.0000000000000348.

PMID:
30179981
6.

Risk factors for heart disease in transfusion-dependent thalassemia: serum ferritin revisited.

Derchi G, Dessì C, Bina P, Cappellini MD, Piga A, Perrotta S, Tartaglione I, Giuditta M, Longo F, Origa R, Quarta A, Pinto V, Forni GL; Webthal®.

Intern Emerg Med. 2018 Jun 12. doi: 10.1007/s11739-018-1890-2. [Epub ahead of print]

PMID:
29948832
7.

Renal safety under long-course deferasirox therapy in iron overloaded transfusion-dependent β-thalassemia and other anemias.

Origa R, Piga A, Tartaglione I, Della Corte G, Forni GL, Bruederle A, Castiglioni C, Han J.

Am J Hematol. 2018 Jul;93(7):E172-E175. doi: 10.1002/ajh.25122. Epub 2018 May 15. No abstract available.

PMID:
29675847
8.

Transient elastography for non-invasive evaluation of post-transplant liver graft fibrosis in children.

Vinciguerra T, Brunati A, David E, Longo F, Pinon M, Ricceri F, Castellino L, Piga A, Giraudo MT, Tandoi F, Cisarò F, Dell Olio D, Isolato G, Romagnoli R, Salizzoni M, Calvo PL.

Pediatr Transplant. 2018 Mar;22(2). doi: 10.1111/petr.13125. Epub 2018 Jan 25.

PMID:
29369488
9.

Impact of bone disease and pain in thalassemia.

Piga A.

Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):272-277. doi: 10.1182/asheducation-2017.1.272. Review.

10.

Clinical relevance of deferasirox trough levels in β-thalassemia patients.

Allegra S, Massano D, De Francia S, Longo F, Piccione F, Pirro E, Cusato J, D'Avolio A, Piga A.

Clin Exp Pharmacol Physiol. 2018 Feb;45(2):213-216. doi: 10.1111/1440-1681.12879. Epub 2017 Dec 4.

PMID:
29205450
11.

Role of CYP24A1, VDR and GC gene polymorphisms on deferasirox pharmacokinetics and clinical outcomes.

Allegra S, Cusato J, De Francia S, Arduino A, Longo F, Pirro E, Massano D, De Nicolò A, Piga A, D'Avolio A.

Pharmacogenomics J. 2018 May 22;18(3):506-515. doi: 10.1038/tpj.2017.43. Epub 2017 Nov 21.

PMID:
29160302
12.

Real-life experience with hydroxyurea in sickle cell disease: A multicenter study in a cohort of patients with heterogeneous descent.

Rigano P, De Franceschi L, Sainati L, Piga A, Piel FB, Cappellini MD, Fidone C, Masera N, Palazzi G, Gianesin B, Forni GL; Italian Multicenter Study of Hydroxyurea in Sickle Cell Anemia Investigators.

Blood Cells Mol Dis. 2018 Mar;69:82-89. doi: 10.1016/j.bcmd.2017.08.017. Epub 2017 Oct 9.

13.

Effect of pharmacogenetic markers of vitamin D pathway on deferasirox pharmacokinetics in children.

Allegra S, Cusato J, De Francia S, Longo F, Pirro E, Massano D, Piga A, D'Avolio A.

Pharmacogenet Genomics. 2018 Jan;28(1):17-22. doi: 10.1097/FPC.0000000000000315.

PMID:
29099735
14.

Treatment of hepatitis C virus infection with direct-acting antiviral drugs is safe and effective in patients with hemoglobinopathies.

Origa R, Ponti ML, Filosa A, Galeota Lanza A, Piga A, Saracco GM, Pinto V, Picciotto A, Rigano P, Madonia S, Rosso R, D'Ascola D, Cappellini MD, D'Ambrosio R, Tartaglione I, De Franceschi L, Gianesin B, Di Marco V, Forni GL; Italy for THAlassemia and hepatitis C Advance - Società Italiana Talassemie ed Emoglobinopatie (ITHACA-SITE).

Am J Hematol. 2017 Dec;92(12):1349-1355. doi: 10.1002/ajh.24911. Epub 2017 Oct 19.

15.

Dual-Energy X-ray Absorptiometry Predictors of Vertebral Deformities in Beta-Thalassemia Major.

Osella G, Priola AM, Priola SM, Piga A, Longo F, Ventura M, Bentivegna G, Angeli A, Veltri A, Terzolo M.

J Clin Densitom. 2018 Oct - Dec;21(4):507-516. doi: 10.1016/j.jocd.2017.06.028. Epub 2017 Jul 27.

PMID:
28756994
16.

Randomised clinical trial: sofosbuvir and ledipasvir in patients with transfusion-dependent thalassaemia and HCV genotype 1 or 4 infection.

Mangia A, Sarli R, Gamberini R, Piga A, Cenderello G, Piazzolla V, Santoro R, Caruso V, Quarta A, Ganga R, Copetti M, Forni G.

Aliment Pharmacol Ther. 2017 Aug;46(4):424-431. doi: 10.1111/apt.14197. Epub 2017 Jun 29.

17.

Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells.

Posadino AM, Phu HT, Cossu A, Giordo R, Fois M, Thuan DTB, Piga A, Sotgia S, Zinellu A, Carru C, Pintus G.

Toxicol In Vitro. 2017 Aug;42:255-262. doi: 10.1016/j.tiv.2017.05.005. Epub 2017 May 7.

PMID:
28495234
18.

The Molecular Spectrum of β- and α-Thalassemia Mutations in Non-Endemic Umbria, Central Italy.

Gorello P, Arcioni F, Palmieri A, Barbanera Y, Ceccuzzi L, Adami C, Marchesi M, Angius A, Minelli O, Onorato M, Piga A, Caniglia M, Mecucci C, Roetto A.

Hemoglobin. 2016 Nov;40(6):371-376. doi: 10.1080/03630269.2017.1289101.

PMID:
28361595
19.

Deferasirox pharmacogenetic influence on pharmacokinetic, efficacy and toxicity in a cohort of pediatric patients.

Allegra S, De Francia S, Cusato J, Arduino A, Massano D, Longo F, Piga A, D'Avolio A.

Pharmacogenomics. 2017 Apr;18(6):539-554. doi: 10.2217/pgs-2016-0176. Epub 2017 Mar 27.

PMID:
28346059
20.

Food losses, shelf life extension and environmental impact of a packaged cheesecake: A life cycle assessment.

Gutierrez MM, Meleddu M, Piga A.

Food Res Int. 2017 Jan;91:124-132. doi: 10.1016/j.foodres.2016.11.031. Epub 2016 Dec 9.

PMID:
28290316
21.

Deferasirox pharmacokinetics evaluation in a woman with hereditary haemochromatosis and heterozygous β-thalassaemia.

Allegra S, De Francia S, Longo F, Massano D, Cusato J, Arduino A, Pirro E, Piga A, D'Avolio A.

Biomed Pharmacother. 2016 Dec;84:1510-1512. doi: 10.1016/j.biopha.2016.11.041. Epub 2016 Nov 20.

PMID:
27881236
22.

Deferasirox pharmacokinetic and toxicity correlation in β-thalassaemia major treatment.

Allegra S, De Francia S, Cusato J, Pirro E, Massano D, Piga A, D'Avolio A.

J Pharm Pharmacol. 2016 Nov;68(11):1417-1421. doi: 10.1111/jphp.12638. Epub 2016 Sep 27.

PMID:
27672004
23.

A randomized trial of amlodipine in addition to standard chelation therapy in patients with thalassemia major.

Fernandes JL, Loggetto SR, Veríssimo MP, Fertrin KY, Baldanzi GR, Fioravante LA, Tan DM, Higa T, Mashima DA, Piga A, Coelho OR, Costa FF, Saad ST.

Blood. 2016 Sep 22;128(12):1555-61. doi: 10.1182/blood-2016-06-721183. Epub 2016 Jul 13.

24.

Deferasirox pharmacokinetic evaluation in β-thalassaemia paediatric patients.

Allegra S, Cusato J, De Francia S, Pirro E, Massano D, Piga A, D'Avolio A.

J Pharm Pharmacol. 2017 May;69(5):525-528. doi: 10.1111/jphp.12559. Epub 2016 May 27.

PMID:
27230486
25.

Deferasirox AUC efficacy cutoff and role of pharmacogenetics.

Allegra S, Cusato J, De Francia S, Massano D, Piga A, D'Avolio A.

Eur J Clin Pharmacol. 2016 Sep;72(9):1155-7. doi: 10.1007/s00228-016-2070-9. Epub 2016 May 18. No abstract available.

PMID:
27193993
26.

Liver stiffness assessed by transient elastography in patients with β thalassaemia major.

Ferraioli G, Lissandrin R, Tinelli C, Scudeller L, Bonetti F, Zicchetti M, Longo F, Murgia M, Bernuzzi S, Zecca M, Casula P, Piga A, Filice C.

Ann Hepatol. 2016 May-Jun;15(3):410-7. doi: 10.5604/16652681.1198817.

PMID:
27049495
27.

Role of pharmacogenetics on deferasirox AUC and efficacy.

Cusato J, Allegra S, De Francia S, Massano D, Piga A, D'Avolio A.

Pharmacogenomics. 2016 Apr;17(6):561-72. doi: 10.2217/pgs-2015-0001. Epub 2016 Apr 4.

PMID:
27043265
28.

Techno-functional and nutritional performance of commercial breads available in Europe.

Conte P, Fadda C, Piga A, Collar C.

Food Sci Technol Int. 2016 Oct;22(7):621-633. Epub 2016 Mar 17.

PMID:
26993878
29.

Revisiting nephrocalcinosis: A single-centre perspective. A northern Italian experience.

Piccoli GB, De Pascale A, Randone O, Vigotti FN, Priola AM, Naretto C, Ferraresi M, Aroasio E, Gonella S, Mongilardi E, Scognamiglio S, Consiglio V, Roggero S, Piga A, Roccatello D, Veltri A.

Nephrology (Carlton). 2016 Feb;21(2):97-107. doi: 10.1111/nep.12535.

PMID:
26058976
30.

Children of a lesser god or miracles? An emotional and behavioural profile of children born to mothers on dialysis in Italy: a multicentre nationwide study 2000-12.

Piccoli GB, Postorino V, Cabiddu G, Ghiotto S, Guzzo G, Roggero S, Manca E, Puddu R, Meloni F, Attini R, Moi P, Guida B, Maxia S, Piga A, Mazzone L, Pani A, Postorino M; ‘Kidney and Pregnancy Study Group’ of the ‘Italian Society of Nephrology’; 'Kidney and Pregnancy Study Group' of the 'Italian Society of Nephrology'.

Nephrol Dial Transplant. 2015 Jul;30(7):1193-202. doi: 10.1093/ndt/gfv127. Epub 2015 Jun 4.

31.

IFNL3 polymorphisms and HCV infection in patients with beta thalassemia.

Origa R, Marceddu G, Danjou F, Perseu L, Satta S, Demartis FR, Piga A, Longo F, Lai ME, Vacquer S, Galanello R.

Ann Hepatol. 2015 May-Jun;14(3):389-95.

32.

Significance of thermal transitions on starch digestibility and firming kinetics of restricted water mixed flour bread matrices.

Collar C, Jiménez T, Conte P, Piga A.

Carbohydr Polym. 2015 May 20;122:169-79. doi: 10.1016/j.carbpol.2014.12.083. Epub 2015 Jan 13.

PMID:
25817656
33.

13-valent pneumococcal conjugate vaccine (PCV13) is immunogenic and safe in children 6-17 years of age with sickle cell disease previously vaccinated with 23-valent pneumococcal polysaccharide vaccine (PPSV23): Results of a phase 3 study.

De Montalembert M, Abboud MR, Fiquet A, Inati A, Lebensburger JD, Kaddah N, Mokhtar G, Piga A, Halasa N, Inusa B, Rees DC, Heath PT, Telfer P, Driscoll C, Al Hajjar S, Tozzi A, Jiang Q, Emini EA, Gruber WC, Gurtman A, Scott DA.

Pediatr Blood Cancer. 2015 Aug;62(8):1427-36. doi: 10.1002/pbc.25502. Epub 2015 Mar 23. Erratum in: Pediatr Blood Cancer. 2019 Feb;66(2):e27554.

PMID:
25810327
34.

A genetic score for the prediction of beta-thalassemia severity.

Danjou F, Francavilla M, Anni F, Satta S, Demartis FR, Perseu L, Manca M, Sollaino MC, Manunza L, Mereu E, Marceddu G, Pissard S, Joly P, Thuret I, Origa R, Borg J, Forni GL, Piga A, Lai ME, Badens C, Moi P, Galanello R.

Haematologica. 2015 Apr;100(4):452-7. doi: 10.3324/haematol.2014.113886. Epub 2014 Dec 5.

35.

Prevalence and distribution of iron overload in patients with transfusion-dependent anemias differs across geographic regions: results from the CORDELIA study.

Aydinok Y, Porter JB, Piga A, Elalfy M, El-Beshlawy A, Kilinç Y, Viprakasit V, Yesilipek A, Habr D, Quebe-Fehling E, Pennell DJ.

Eur J Haematol. 2015 Sep;95(3):244-53. doi: 10.1111/ejh.12487. Epub 2015 Jan 8.

36.

Deferasirox effect on renal haemodynamic parameters in patients with transfusion-dependent β thalassaemia.

Piga A, Fracchia S, Lai ME, Cappellini MD, Hirschberg R, Habr D, Wegener A, Bouillaud E, Forni GL.

Br J Haematol. 2015 Mar;168(6):882-90. doi: 10.1111/bjh.13217. Epub 2014 Nov 17.

37.

Influence of single-nucleotide polymorphisms on deferasirox C trough levels and effectiveness.

Cusato J, Allegra S, Massano D, De Francia S, Piga A, D'Avolio A.

Pharmacogenomics J. 2015 Jun;15(3):263-71. doi: 10.1038/tpj.2014.65. Epub 2014 Oct 28.

PMID:
25348619
38.

Sustained improvements in myocardial T2* over 2 years in severely iron-overloaded patients with beta thalassemia major treated with deferasirox or deferoxamine.

Pennell DJ, Porter JB, Piga A, Lai YR, El-Beshlawy A, Elalfy M, Yesilipek A, Kilinç Y, Habr D, Musallam KM, Shen J, Aydinok Y; CORDELIA study investigators.

Am J Hematol. 2015 Feb;90(2):91-6. doi: 10.1002/ajh.23876. Epub 2014 Nov 19.

39.

Gluten-free dough-making of specialty breads: Significance of blended starches, flours and additives on dough behaviour.

Collar C, Conte P, Fadda C, Piga A.

Food Sci Technol Int. 2015 Oct;21(7):523-36. doi: 10.1177/1082013214552862. Epub 2014 Sep 17.

PMID:
25231269
40.

Epigenetic therapy for Friedreich ataxia.

Soragni E, Miao W, Iudicello M, Jacoby D, De Mercanti S, Clerico M, Longo F, Piga A, Ku S, Campau E, Du J, Penalver P, Rai M, Madara JC, Nazor K, O'Connor M, Maximov A, Loring JF, Pandolfo M, Durelli L, Gottesfeld JM, Rusche JR.

Ann Neurol. 2014 Oct;76(4):489-508. doi: 10.1002/ana.24260. Epub 2014 Sep 16.

41.

Microhematuria in a patient with beta-thalassemia major: a casual or a causal association?

Piccoli GB, Roggero S, De Pascale A, Vigotti FN, Piga A, Veltri A.

Kidney Int. 2014 Aug;86(2):450-2. doi: 10.1038/ki.2013.380. No abstract available.

42.

Hepatocellular carcinoma in thalassaemia: an update of the Italian Registry.

Borgna-Pignatti C, Garani MC, Forni GL, Cappellini MD, Cassinerio E, Fidone C, Spadola V, Maggio A, Restivo Pantalone G, Piga A, Longo F, Gamberini MR, Ricchi P, Costantini S, D'Ascola D, Cianciulli P, Lai ME, Carta MP, Ciancio A, Cavalli P, Putti MC, Barella S, Amendola G, Campisi S, Capra M, Caruso V, Colletta G, Volpato S.

Br J Haematol. 2014 Oct;167(1):121-6. doi: 10.1111/bjh.13009. Epub 2014 Jul 3.

PMID:
24992281
43.

Deferasirox for cardiac siderosis in β-thalassaemia major: a multicentre, open label, prospective study.

Piga A, Longo F, Origa R, Roggero S, Pinna F, Zappu A, Castiglioni C, Cappellini MD.

Br J Haematol. 2014 Nov;167(3):423-6. doi: 10.1111/bjh.12987. Epub 2014 Jun 30. No abstract available.

PMID:
24976388
44.

Management of pulmonary arterial hypertension associated to thalassemia: when pulmonary endarterectomy is the best therapeutical option? A case report.

Roggero S, Vullo S, Volpe G, Piga A, Albera C.

J Thromb Thrombolysis. 2015 Jan;39(1):139-43. doi: 10.1007/s11239-014-1073-6.

PMID:
24788071
45.

Complete recovery from paraparesis in spinal cord compression due to extramedullary haemopoiesis in beta-thalassaemia by emergency radiation therapy.

Ruo Redda MG, Allis S, Reali A, Bartoncini S, Roggero S, Anglesio SM, Piga A.

Intern Med J. 2014 Apr;44(4):409-12. doi: 10.1111/imj.12386. Review.

PMID:
24754690
46.

A 1-year randomized controlled trial of deferasirox vs deferoxamine for myocardial iron removal in β-thalassemia major (CORDELIA).

Pennell DJ, Porter JB, Piga A, Lai Y, El-Beshlawy A, Belhoul KM, Elalfy M, Yesilipek A, Kilinç Y, Lawniczek T, Habr D, Weisskopf M, Zhang Y, Aydinok Y; CORDELIA study investigators.

Blood. 2014 Mar 6;123(10):1447-54. doi: 10.1182/blood-2013-04-497842. Epub 2014 Jan 2.

47.

Guidelines for the Clinical Management of Thalassaemia [Internet].

Cappellini MD, Cohen A, Eleftheriou A, Piga A, Porter J, Taher A.

2nd Revised edition. Nicosia (CY): Thalassaemia International Federation; 2008.

48.

α-globin gene quadruplication and heterozygous β-thalassemia: a not so rare cause of thalassemia intermedia.

Origa R, Sollaino MC, Borgna-Pignatti C, Piga A, Feliu Torres A, Masile V, Galanello R.

Acta Haematol. 2014;131(3):162-4. doi: 10.1159/000353410. Epub 2013 Nov 6. No abstract available.

PMID:
24217654
49.

Prevalence and risk factors for pulmonary arterial hypertension in a large group of β-thalassemia patients using right heart catheterization: a Webthal study.

Derchi G, Galanello R, Bina P, Cappellini MD, Piga A, Lai ME, Quarta A, Casu G, Perrotta S, Pinto V, Musallam KM, Forni GL; Webthal Pulmonary Arterial Hypertension Group*.

Circulation. 2014 Jan 21;129(3):338-45. doi: 10.1161/CIRCULATIONAHA.113.002124. Epub 2013 Sep 30.

PMID:
24081970
50.

Amlodipine reduces cardiac iron overload in patients with thalassemia major: a pilot trial.

Fernandes JL, Sampaio EF, Fertrin K, Coelho OR, Loggetto S, Piga A, Verissimo M, Saad ST.

Am J Med. 2013 Sep;126(9):834-7. doi: 10.1016/j.amjmed.2013.05.002. Epub 2013 Jul 3.

PMID:
23830536

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