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Items: 1 to 50 of 70

1.

Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters.

Kalaba P, Ilić M, Aher NY, Dragačević V, Wieder M, Zehl M, Wackerlig J, Beyl S, Sartori SB, Ebner K, Roller A, Lukic N, Beryozkina T, Gonzalez ERP, Neill P, Khan JA, Bakulev V, Leban JJ, Hering S, Pifl C, Singewald N, Lubec J, Urban E, Sitte HH, Langer T, Lubec G.

J Med Chem. 2020 Jan 9;63(1):391-417. doi: 10.1021/acs.jmedchem.9b01938. Epub 2019 Dec 30.

PMID:
31841637
2.

The time delay between in vivo imaging and postmortem data poses a caveat on "no link" findings.

Pifl C.

Mov Disord. 2019 Oct;34(10):1579-1580. doi: 10.1002/mds.27847. No abstract available.

3.

Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants.

Korchynska S, Krassnitzer M, Malenczyk K, Prasad RB, Tretiakov EO, Rehman S, Cinquina V, Gernedl V, Farlik M, Petersen J, Hannes S, Schachenhofer J, Reisinger SN, Zambon A, Asplund O, Artner I, Keimpema E, Lubec G, Mulder J, Bock C, Pollak DD, Romanov RA, Pifl C, Groop L, Hökfelt TG, Harkany T.

EMBO J. 2020 Jan 2;39(1):e100882. doi: 10.15252/embj.2018100882. Epub 2019 Nov 21.

4.

Distinct gradients of various neurotransmitter markers in caudate nucleus and putamen of the human brain.

Hörtnagl H, Pifl C, Hörtnagl E, Reiner A, Sperk G.

J Neurochem. 2019 Oct 14. doi: 10.1111/jnc.14897. [Epub ahead of print]

PMID:
31608979
5.

Disturbed neurotransmitter homeostasis in ether lipid deficiency.

Dorninger F, König T, Scholze P, Berger ML, Zeitler G, Wiesinger C, Gundacker A, Pollak DD, Huck S, Just WW, Forss-Petter S, Pifl C, Berger J.

Hum Mol Genet. 2019 Jun 15;28(12):2046-2061. doi: 10.1093/hmg/ddz040.

6.

Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress.

Alpár A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, Pifl C, Zachar G, Perugini J, Severi I, Leitgeb P, Bakker J, Miklosi AG, Tretiakov E, Keimpema E, Arque G, Tasan RO, Sperk G, Malenczyk K, Máté Z, Erdélyi F, Szabó G, Lubec G, Palkovits M, Giordano A, Hökfelt TG, Romanov RA, Horvath TL, Harkany T.

EMBO J. 2018 Nov 2;37(21). pii: e100087. doi: 10.15252/embj.2018100087. Epub 2018 Sep 12.

7.

The psychostimulant (±)-cis-4,4'-dimethylaminorex (4,4'-DMAR) interacts with human plasmalemmal and vesicular monoamine transporters.

Maier J, Mayer FP, Luethi D, Holy M, Jäntsch K, Reither H, Hirtler L, Hoener MC, Liechti ME, Pifl C, Brandt SD, Sitte HH.

Neuropharmacology. 2018 Aug;138:282-291. doi: 10.1016/j.neuropharm.2018.06.018. Epub 2018 Jun 23.

8.

Early Paradoxical Increase of Dopamine: A Neurochemical Study of Olfactory Bulb in Asymptomatic and Symptomatic MPTP Treated Monkeys.

Pifl C, Reither H, Del Rey NL, Cavada C, Obeso JA, Blesa J.

Front Neuroanat. 2017 May 29;11:46. doi: 10.3389/fnana.2017.00046. eCollection 2017.

9.

Dopamine and noradrenaline, but not serotonin, in the human claustrum are greatly reduced in patients with Parkinson's disease: possible functional implications.

Sitte HH, Pifl C, Rajput AH, Hörtnagl H, Tong J, Lloyd GK, Kish SJ, Hornykiewicz O.

Eur J Neurosci. 2017 May;45(10):1356. doi: 10.1111/ejn.13573. No abstract available.

PMID:
28523903
10.

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model.

Rivetti di Val Cervo P, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sánchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, Arenas E.

Nat Biotechnol. 2017 May;35(5):444-452. doi: 10.1038/nbt.3835. Epub 2017 Apr 10.

PMID:
28398344
11.

Dopamine and noradrenaline, but not serotonin, in the human claustrum are greatly reduced in patients with Parkinson's disease: possible functional implications.

Sitte HH, Pifl C, Rajput AH, Hörtnagl H, Tong J, Lloyd GK, Kish SJ, Hornykiewicz O.

Eur J Neurosci. 2017 Jan;45(1):192-197. doi: 10.1111/ejn.13435. Epub 2016 Nov 11. Erratum in: Eur J Neurosci. 2017 May;45(10 ):1356.

PMID:
27741357
12.

Problems with traffic ahead: Synaptic vesicles in Parkinson's disease.

Pifl C.

Mov Disord. 2016 Oct;31(10):1480. doi: 10.1002/mds.26735. No abstract available.

PMID:
27477200
13.

Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice.

Peneder TM, Bauer J, Pifl C.

Mov Disord. 2016 Nov;31(11):1729-1733. doi: 10.1002/mds.26695. Epub 2016 Jun 14.

PMID:
27297192
14.

The profile of mephedrone on human monoamine transporters differs from 3,4-methylenedioxymethamphetamine primarily by lower potency at the vesicular monoamine transporter.

Pifl C, Reither H, Hornykiewicz O.

Eur J Pharmacol. 2015 May 15;755:119-26. doi: 10.1016/j.ejphar.2015.03.004. Epub 2015 Mar 11.

PMID:
25771452
15.

Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum.

Pifl C, Rajput A, Reither H, Blesa J, Cavada C, Obeso JA, Rajput AH, Hornykiewicz O.

J Neurosci. 2014 Jun 11;34(24):8210-8. doi: 10.1523/JNEUROSCI.5456-13.2014. Erratum in: J Neurosci. 2015 Nov 25;35(47):15767.

16.

Reduced noradrenaline, but not dopamine and serotonin in motor thalamus of the MPTP primate: relation to severity of parkinsonism.

Pifl C, Hornykiewicz O, Blesa J, Adánez R, Cavada C, Obeso JA.

J Neurochem. 2013 Jun;125(5):657-62. doi: 10.1111/jnc.12162. Epub 2013 Feb 13.

17.

Thalamic noradrenaline in Parkinson's disease: deficits suggest role in motor and non-motor symptoms.

Pifl C, Kish SJ, Hornykiewicz O.

Mov Disord. 2012 Nov;27(13):1618-24. doi: 10.1002/mds.25109. Epub 2012 Oct 4.

18.

The nigrostriatal system in the presymptomatic and symptomatic stages in the MPTP monkey model: a PET, histological and biochemical study.

Blesa J, Pifl C, Sánchez-González MA, Juri C, García-Cabezas MA, Adánez R, Iglesias E, Collantes M, Peñuelas I, Sánchez-Hernández JJ, Rodríguez-Oroz MC, Avendaño C, Hornykiewicz O, Cavada C, Obeso JA.

Neurobiol Dis. 2012 Oct;48(1):79-91. doi: 10.1016/j.nbd.2012.05.018. Epub 2012 Jun 5.

PMID:
22677034
19.

The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine.

Sommerauer C, Rebernik P, Reither H, Nanoff C, Pifl C.

Neuropharmacology. 2012 Mar;62(4):1708-16. doi: 10.1016/j.neuropharm.2011.11.017. Epub 2011 Dec 6.

PMID:
22155208
20.

Effects of NMDA receptor modulators on a blood-brain barrier in vitro model.

Neuhaus W, Freidl M, Szkokan P, Berger M, Wirth M, Winkler J, Gabor F, Pifl C, Noe CR.

Brain Res. 2011 Jun 7;1394:49-61. doi: 10.1016/j.brainres.2011.04.003. Epub 2011 Apr 13.

PMID:
21549356
21.

Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients.

Sperk G, Wieselthaler-Hölzl A, Pirker S, Tasan R, Strasser SS, Drexel M, Pifl C, Marschalek J, Ortler M, Trinka E, Heitmair-Wietzorrek K, Ciofi P, Feucht M, Baumgartner C, Czech T.

Hippocampus. 2012 Mar;22(3):590-603. doi: 10.1002/hipo.20923. Epub 2011 Apr 20.

22.

Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice.

Peneder TM, Scholze P, Berger ML, Reither H, Heinze G, Bertl J, Bauer J, Richfield EK, Hornykiewicz O, Pifl C.

Neuroscience. 2011 Apr 28;180:280-92. doi: 10.1016/j.neuroscience.2011.02.017. Epub 2011 Feb 16.

PMID:
21333719
23.

Central control of fever and female body temperature by RANKL/RANK.

Hanada R, Leibbrandt A, Hanada T, Kitaoka S, Furuyashiki T, Fujihara H, Trichereau J, Paolino M, Qadri F, Plehm R, Klaere S, Komnenovic V, Mimata H, Yoshimatsu H, Takahashi N, von Haeseler A, Bader M, Kilic SS, Ueta Y, Pifl C, Narumiya S, Penninger JM.

Nature. 2009 Nov 26;462(7272):505-9. doi: 10.1038/nature08596.

PMID:
19940926
24.

Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner.

Pifl C, Wolf A, Rebernik P, Reither H, Berger ML.

Neuropharmacology. 2009 Feb;56(2):531-40. doi: 10.1016/j.neuropharm.2008.10.009. Epub 2008 Oct 26.

PMID:
19000913
25.

Globus pallidus dopamine and Parkinson motor subtypes: clinical and brain biochemical correlation.

Rajput AH, Sitte HH, Rajput A, Fenton ME, Pifl C, Hornykiewicz O.

Neurology. 2008 Apr 15;70(16 Pt 2):1403-10. doi: 10.1212/01.wnl.0000285082.18969.3a. Epub 2008 Jan 2.

PMID:
18172064
26.

Current topics in brain dopamine research: a tribute to Professor Oleh Hornykiewicz.

Pifl C, Sperk G.

Wien Klin Wochenschr. 2006 Oct;118(19-20):563-5. No abstract available.

PMID:
17136327
27.

Dopamine turnover is upregulated in the caudate/putamen of asymptomatic MPTP-treated rhesus monkeys.

Pifl C, Hornykiewicz O.

Neurochem Int. 2006 Oct;49(5):519-24. Epub 2006 May 15.

PMID:
16698121
28.

Pharmacological characterization of ecstasy synthesis byproducts with recombinant human monoamine transporters.

Pifl C, Nagy G, Berényi S, Kattinger A, Reither H, Antus S.

J Pharmacol Exp Ther. 2005 Jul;314(1):346-54. Epub 2005 Apr 14.

PMID:
15831439
29.

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.

Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA.

Hum Mol Genet. 2005 May 1;14(9):1231-41. Epub 2005 Mar 24.

PMID:
15790595
30.

Dopamine inhibits cell growth and cell cycle by blocking ribonucleotide reductase.

Woldman I, Reither H, Kattinger A, Hornykiewicz O, Pifl C.

Neuropharmacology. 2005 Mar;48(4):525-37. Epub 2005 Jan 25.

PMID:
15755480
31.

Human brain dopamine metabolism in levodopa-induced dyskinesia and wearing-off.

Rajput AH, Fenton ME, Di Paolo T, Sitte H, Pifl C, Hornykiewicz O.

Parkinsonism Relat Disord. 2004 Jun;10(4):221-6.

PMID:
15120096
32.

alpha-Synuclein selectively increases manganese-induced viability loss in SK-N-MC neuroblastoma cells expressing the human dopamine transporter.

Pifl C, Khorchide M, Kattinger A, Reither H, Hardy J, Hornykiewicz O.

Neurosci Lett. 2004 Jan 2;354(1):34-7.

PMID:
14698476
33.

Zn2+ modulates currents generated by the dopamine transporter: parallel effects on amphetamine-induced charge transfer and release.

Pifl C, Rebernik P, Kattinger A, Reither H.

Neuropharmacology. 2004 Feb;46(2):223-31.

PMID:
14680760
34.

Cellular effects of dopamine--beyond oxidative mechanisms.

Pifl C, Kattinger A, Reither H, Hornykiewicz O.

Parkinsonism Relat Disord. 2002 Sep;8(6):433-7.

PMID:
12217632
35.

Organic cation transporter mRNA and function in the rat superior cervical ganglion.

Kristufek D, Rudorfer W, Pifl C, Huck S.

J Physiol. 2002 Aug 15;543(Pt 1):117-34.

36.

Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter.

Pifl C, Zezula J, Spittler A, Kattinger A, Reither H, Caron MG, Hornykiewicz O.

FASEB J. 2001 Jul;15(9):1607-9. No abstract available.

PMID:
11427501
38.

Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter.

Scholze P, Zwach J, Kattinger A, Pifl C, Singer EA, Sitte HH.

J Pharmacol Exp Ther. 2000 Jun;293(3):870-8.

PMID:
10869387
39.
41.

Striatal biopterin and tyrosine hydroxylase protein reduction in dopa-responsive dystonia.

Furukawa Y, Nygaard TG, Gütlich M, Rajput AH, Pifl C, DiStefano L, Chang LJ, Price K, Shimadzu M, Hornykiewicz O, Haycock JW, Kish SJ.

Neurology. 1999 Sep 22;53(5):1032-41.

PMID:
10496263
42.
44.

Induction of apoptosis in vitro and in vivo by the cholinergic neurotoxin ethylcholine aziridinium.

Rinner WA, Pifl C, Lassmann H, Hörtnagl H.

Neuroscience. 1997 Jul;79(2):535-42.

PMID:
9200736
45.
46.

Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease.

Wilson JM, Levey AI, Rajput A, Ang L, Guttman M, Shannak K, Niznik HB, Hornykiewicz O, Pifl C, Kish SJ.

Neurology. 1996 Sep;47(3):718-26.

PMID:
8797470
47.
48.

The dopamine transporter. The cloned target site of parkinsonism-inducing toxins and of drugs of abuse.

Pifl C, Giros B, Caron MG.

Adv Neurol. 1996;69:235-8. Review. No abstract available.

PMID:
8615133
49.
50.

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