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Synthesis and Cyclooxygenase Inhibition of Sulfonamide-Substituted (Dihydro)Pyrrolo[3,2,1-hi]indoles and Their Potential Prodrugs.

Laube M, Gassner C, Kniess T, Pietzsch J.

Molecules. 2019 Oct 22;24(20). pii: E3807. doi: 10.3390/molecules24203807.


A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR.

Arndt C, Feldmann A, Koristka S, Schäfer M, Bergmann R, Mitwasi N, Berndt N, Bachmann D, Kegler A, Schmitz M, Puentes-Cala E, Soto JA, Ehninger G, Pietzsch J, Liolios C, Wunderlich G, Kotzerke J, Kopka K, Bachmann M.

Oncoimmunology. 2019 Sep 7;8(11):1659095. doi: 10.1080/2162402X.2019.1659095. eCollection 2019.


Current Management of Pheochromocytoma/Paraganglioma: A Guide for the Practicing Clinician in the Era of Precision Medicine.

Nölting S, Ullrich M, Pietzsch J, Ziegler CG, Eisenhofer G, Grossman A, Pacak K.

Cancers (Basel). 2019 Oct 8;11(10). pii: E1505. doi: 10.3390/cancers11101505. Review.


Biomaterials in repairing rat femoral defects: In vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies.

Neuber C, Schulze S, Förster Y, Hofheinz F, Wodke J, Möller S, Schnabelrauch M, Hintze V, Scharnweber D, Rammelt S, Pietzsch J.

Clin Hemorheol Microcirc. 2019;73(1):177-194. doi: 10.3233/CH-199208.


Carboranyl Analogues of Ketoprofen with Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines.

Buzharevski A, Paskas S, Laube M, Lönnecke P, Neumann W, Murganic B, Mijatovic S, Maksimovic-Ivanic D, Pietzsch J, Hey-Hawkins E.

ACS Omega. 2019 May 23;4(5):8824-8833. doi: 10.1021/acsomega.9b00412. eCollection 2019 May 31.


Cost-effectiveness of transcatheter versus surgical aortic valve replacement in patients at lower surgical risk: results from the NOTION trial.

Geisler BP, Jørgensen TH, Thyregod HGH, Pietzsch JB, Søndergaard L.

EuroIntervention. 2019 Dec 6;15(11):e959-e967. doi: 10.4244/EIJ-D-18-00847.


Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network.

Xu Y, Patsis PA, Hauser S, Voigt D, Rothe R, Günther M, Cui M, Yang X, Wieduwild R, Eckert K, Neinhuis C, Akbar TF, Minev IR, Pietzsch J, Zhang Y.

Adv Sci (Weinh). 2019 May 24;6(15):1802077. doi: 10.1002/advs.201802077. eCollection 2019 Aug 7.


Adjuvant drug-assisted bone healing: Part III - Further strategies for local and systemic modulation.

Rothe R, Schulze S, Neuber C, Hauser S, Rammelt S, Pietzsch J.

Clin Hemorheol Microcirc. 2019 Jun 3. doi: 10.3233/CH-199104. [Epub ahead of print]


Adjuvant drug-assisted bone healing: Part II - Modulation of angiogenesis.

Rothe R, Schulze S, Neuber C, Hauser S, Rammelt S, Pietzsch J.

Clin Hemorheol Microcirc. 2019 Jun 3. doi: 10.3233/CH-199103. [Epub ahead of print]


Adjuvant drug-assisted bone healing: Part I - Modulation of inflammation.

Rothe R, Schulze S, Neuber C, Hauser S, Rammelt S, Pietzsch J.

Clin Hemorheol Microcirc. 2019 Jun 3. doi: 10.3233/CH-199102. [Epub ahead of print]


Regulation of bone regeneration.

Jung F, Pietzsch J.

Clin Hemorheol Microcirc. 2019 May 29. doi: 10.3233/CH-199101. [Epub ahead of print] No abstract available.


Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background.

Ullrich M, Richter S, Seifert V, Hauser S, Calsina B, Martínez-Montes ÁM, Ter Laak M, Ziegler CG, Timmers H, Eisenhofer G, Robledo M, Pietzsch J.

Cancers (Basel). 2019 May 28;11(6). pii: E743. doi: 10.3390/cancers11060743.


Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC.

Sinnes JP, Nagel J, Waldron BP, Maina T, Nock BA, Bergmann RK, Ullrich M, Pietzsch J, Bachmann M, Baum RP, Rösch F.

EJNMMI Res. 2019 May 23;9(1):48. doi: 10.1186/s13550-019-0516-7.


Nitric Oxide-Releasing Selective Estrogen Receptor Modulators: A Bifunctional Approach to Improve the Therapeutic Index.

Bechmann N, Kniess T, Pietzsch J.

J Med Chem. 2019 Jul 25;62(14):6525-6539. doi: 10.1021/acs.jmedchem.9b00171. Epub 2019 Jun 4.


Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells.

Bechmann N, Poser I, Seifert V, Greunke C, Ullrich M, Qin N, Walch A, Peitzsch M, Robledo M, Pacak K, Pietzsch J, Richter S, Eisenhofer G.

Cancers (Basel). 2019 Apr 28;11(5). pii: E594. doi: 10.3390/cancers11050594.


Model to evaluate the impact of hospital-based interventions targeting false-positive blood cultures on economic and clinical outcomes.

Geisler BP, Jilg N, Patton RG, Pietzsch JB.

J Hosp Infect. 2019 Aug;102(4):438-444. doi: 10.1016/j.jhin.2019.03.012. Epub 2019 Mar 27.


Clinical and Economic Benefits of Upper Airway Stimulation for Obstructive Sleep Apnea in a European Setting.

Pietzsch JB, Richter AK, Randerath W, Steffen A, Liu S, Geisler BP, Wasem J, Biermann-Stallwitz J.

Respiration. 2019;98(1):38-47. doi: 10.1159/000497101. Epub 2019 Mar 28.


Radiochemical and radiopharmacological characterization of a 64 Cu-labeled α-MSH analog conjugated with different chelators.

Gao F, Sihver W, Bergmann R, Walther M, Stephan H, Belter B, Neuber C, Haase-Kohn C, Bolzati C, Pietzsch J, Pietzsch HJ.

J Labelled Comp Radiopharm. 2019 Jun 30;62(8):495-509. doi: 10.1002/jlcr.3728. Epub 2019 Jun 17.


Synthesis and preliminary radiopharmacological characterisation of an 11 C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins.

Laube M, Frizler M, Wodtke R, Neuber C, Belter B, Kniess T, Bachmann M, Gütschow M, Pietzsch J, Löser R.

J Labelled Comp Radiopharm. 2019 Jun 30;62(8):448-459. doi: 10.1002/jlcr.3729. Epub 2019 May 15.


Fluorine-18 Labeling of S100 Proteins for Small Animal Positron Emission Tomography.

Laube M, Kniess T, Neuber C, Haase-Kohn C, Pietzsch J.

Methods Mol Biol. 2019;1929:461-485. doi: 10.1007/978-1-4939-9030-6_29.


Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines.

Buzharevski A, Paskas S, Sárosi MB, Laube M, Lönnecke P, Neumann W, Mijatovic S, Maksimovic-Ivanic D, Pietzsch J, Hey-Hawkins E.

ChemMedChem. 2019 Feb 5;14(3):315-321. doi: 10.1002/cmdc.201800685. Epub 2019 Jan 23.


Diverse effects of phospholipase A2 receptor expression on LNCaP and PC-3 prostate cancer cell growth in vitro and in vivo.

Friedemann M, Nacke B, Hagelgans A, Jandeck C, Bechmann N, Ullrich M, Belter B, Neuber C, Sukocheva O, Pietzsch J, Menschikowski M.

Oncotarget. 2018 Nov 13;9(89):35983-35996. doi: 10.18632/oncotarget.26316. eCollection 2018 Nov 13.


Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

Ullrich M, Liers J, Peitzsch M, Feldmann A, Bergmann R, Sommer U, Richter S, Bornstein SR, Bachmann M, Eisenhofer G, Ziegler CG, Pietzsch J.

Endocr Relat Cancer. 2018 Oct 5;25(12):993-1004. doi: 10.1530/ERC-18-0136.


Correction: Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity.

Roscales S, Bechmann N, Weiss DH, Köckerling M, Pietzsch J, Kniess T.

Medchemcomm. 2018 Mar 7;9(3):591-592. doi: 10.1039/c8md90011f. eCollection 2018 Mar 1.


Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide.

Löser R, Bader M, Kuchar M, Wodtke R, Lenk J, Wodtke J, Kuhne K, Bergmann R, Haase-Kohn C, Urbanová M, Steinbach J, Pietzsch J.

Amino Acids. 2019 Feb;51(2):219-244. doi: 10.1007/s00726-018-2657-9. Epub 2018 Sep 27.


Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells.

Loureiro LR, Feldmann A, Bergmann R, Koristka S, Berndt N, Arndt C, Pietzsch J, Novo C, Videira P, Bachmann M.

Blood Cancer J. 2018 Aug 22;8(9):81. doi: 10.1038/s41408-018-0113-4. No abstract available.


Adoption Patterns of Bronchoscopic Lung Volume Reduction Procedures in Germany and Predicted Procedure Volumes for Other European Countries.

Pietzsch JB, Busca R, Rott C, Geisler BP, Weber SA, Slebos DJ, Deslee G, Herth FJF.

Respiration. 2019;97(1):34-41. doi: 10.1159/000491677. Epub 2018 Aug 17.


Insights from eight years of adoption experience of transcatheter mitral valve repair in Germany: observed utilisation patterns and impact on overall mitral valve procedure volumes.

Schaefer A, Lubos E, Pietzsch JB, Pietzsch M, Weber S, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.

EuroIntervention. 2018 Oct 12;14(9):e981-e987. doi: 10.4244/EIJ-D-18-00403.


Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity.

Roscales S, Bechmann N, Weiss DH, Köckerling M, Pietzsch J, Kniess T.

Medchemcomm. 2018 Feb 13;9(3):534-544. doi: 10.1039/c7md00575j. eCollection 2018 Mar 1. Erratum in: Medchemcomm. 2018 Mar 7;9(3):591-592.


Exploring pitfalls of 64Cu-labeled EGFR-targeting peptide GE11 as a potential PET tracer.

Striese F, Sihver W, Gao F, Bergmann R, Walther M, Pietzsch J, Steinbach J, Pietzsch HJ.

Amino Acids. 2018 Oct;50(10):1415-1431. doi: 10.1007/s00726-018-2616-5. Epub 2018 Jul 23.


Should Surgical Repair Be Recommended Over Nonoperative Management for Medial Meniscus Root Tears? Response.

Faucett SC, Geisler BP, Chahla J, Krych AJ, LaPrade RF, Pietzsch JB.

Am J Sports Med. 2018 Jul;46(9):NP44-NP45. doi: 10.1177/0363546518783956. No abstract available.


Changes in medication cost observed in chronic cluster headache patients treated with sphenopalatine ganglion (SPG) stimulation: Analysis based on 1-year data from the Pathway R-1 Registry.

Pietzsch JB, Weber SA, Lund N, Gaul C.

Cephalalgia. 2018 Jul;38(8):1455-1462. doi: 10.1177/0333102418784689. Epub 2018 Jun 19.


Sex differences in discharge destination following acute myocardial infarction.

Perl L, Peiffer V, Fuhrer AE, D'Ascenzo F, Pietzsch JB.

Coron Artery Dis. 2018 Sep;29(6):502-510. doi: 10.1097/MCA.0000000000000643.


From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo.

Albert S, Arndt C, Koristka S, Berndt N, Bergmann R, Feldmann A, Schmitz M, Pietzsch J, Steinbach J, Bachmann M.

Oncotarget. 2018 May 22;9(39):25597-25616. doi: 10.18632/oncotarget.25390. eCollection 2018 May 22.


Evaluation of Fluorine-18-Labeled α1(I)-N-Telopeptide Analogs as Substrate-Based Radiotracers for PET Imaging of Melanoma-Associated Lysyl Oxidase.

Kuchar M, Neuber C, Belter B, Bergmann R, Lenk J, Wodtke R, Kniess T, Steinbach J, Pietzsch J, Löser R.

Front Chem. 2018 Apr 26;6:121. doi: 10.3389/fchem.2018.00121. eCollection 2018.


Nε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling.

Wodtke R, Hauser C, Ruiz-Gómez G, Jäckel E, Bauer D, Lohse M, Wong A, Pufe J, Ludwig FA, Fischer S, Hauser S, Greif D, Pisabarro MT, Pietzsch J, Pietsch M, Löser R.

J Med Chem. 2018 May 24;61(10):4528-4560. doi: 10.1021/acs.jmedchem.8b00286. Epub 2018 May 10.


Synthesis, Characterization, and Initial Biological Evaluation of [99m Tc]Tc-Tricarbonyl-labeled DPA-α-MSH Peptide Derivatives for Potential Melanoma Imaging.

Gao F, Sihver W, Bergmann R, Belter B, Bolzati C, Salvarese N, Steinbach J, Pietzsch J, Pietzsch HJ.

ChemMedChem. 2018 Jun 6;13(11):1146-1158. doi: 10.1002/cmdc.201800110. Epub 2018 Apr 23.


Causative treatment of acid aspiration induced acute lung injury - Recent trends from animal experiments and critical perspective.

Gramatté J, Pietzsch J, Bergmann R, Richter T.

Clin Hemorheol Microcirc. 2018;69(1-2):187-195. doi: 10.3233/CH-189113.


Bridging from Brain to Tumor Imaging: (S)-(-)- and (R)-(+)-[18F]Fluspidine for Investigation of Sigma-1 Receptors in Tumor-Bearing Mice.

Kranz M, Bergmann R, Kniess T, Belter B, Neuber C, Cai Z, Deng G, Fischer S, Zhou J, Huang Y, Brust P, Deuther-Conrad W, Pietzsch J.

Molecules. 2018 Mar 20;23(3). pii: E702. doi: 10.3390/molecules23030702.


Meniscus Root Repair vs Meniscectomy or Nonoperative Management to Prevent Knee Osteoarthritis After Medial Meniscus Root Tears: Clinical and Economic Effectiveness.

Faucett SC, Geisler BP, Chahla J, Krych AJ, Kurzweil PR, Garner AM, Liu S, LaPrade RF, Pietzsch JB.

Am J Sports Med. 2019 Mar;47(3):762-769. doi: 10.1177/0363546518755754. Epub 2018 Mar 8.


Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology.

Koristka S, Kegler A, Bergmann R, Arndt C, Feldmann A, Albert S, Cartellieri M, Ehninger A, Ehninger G, Middeke JM, Bornhäuser M, Schmitz M, Pietzsch J, Akgün K, Ziemssen T, Steinbach J, Bachmann MP.

J Autoimmun. 2018 Jun;90:116-131. doi: 10.1016/j.jaut.2018.02.006. Epub 2018 Mar 2.


Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells.

Bachmann D, Aliperta R, Bergmann R, Feldmann A, Koristka S, Arndt C, Loff S, Welzel P, Albert S, Kegler A, Ehninger A, Cartellieri M, Ehninger G, Bornhäuser M, von Bonin M, Werner C, Pietzsch J, Steinbach J, Bachmann M.

Oncotarget. 2017 Dec 21;9(7):7487-7500. doi: 10.18632/oncotarget.23556. eCollection 2018 Jan 26.


Overexpression of Receptor Tyrosine Kinase EphB4 Triggers Tumor Growth and Hypoxia in A375 Melanoma Xenografts: Insights from Multitracer Small Animal Imaging Experiments.

Neuber C, Belter B, Meister S, Hofheinz F, Bergmann R, Pietzsch HJ, Pietzsch J.

Molecules. 2018 Feb 17;23(2). pii: E444. doi: 10.3390/molecules23020444.


Biomarkers in Malignant Melanoma: Recent Trends and Critical Perspective.

Belter B, Haase-Kohn C, Pietzsch J.

In: Ward WH, Farma JM, editors. Cutaneous Melanoma: Etiology and Therapy [Internet]. Brisbane (AU): Codon Publications; 2017 Dec 21. Chapter 3.


Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells.

Mitwasi N, Feldmann A, Bergmann R, Berndt N, Arndt C, Koristka S, Kegler A, Jureczek J, Hoffmann A, Ehninger A, Cartellieri M, Albert S, Rossig C, Ehninger G, Pietzsch J, Steinbach J, Bachmann M.

Oncotarget. 2017 Sep 18;8(65):108584-108603. doi: 10.18632/oncotarget.21017. eCollection 2017 Dec 12.


An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment.

Huebner D, Rieger C, Bergmann R, Ullrich M, Meister S, Toma M, Wiedemuth R, Temme A, Novotny V, Wirth MP, Bachmann M, Pietzsch J, Fuessel S.

BMC Cancer. 2017 Nov 23;17(1):790. doi: 10.1186/s12885-017-3778-3.


Cost-effectiveness of orbital atherectomy compared to rotational atherectomy in treating patients with severely calcified coronary artery lesions in Japan.

Pietzsch JB, Geisler BP, Ikeno F.

Cardiovasc Interv Ther. 2018 Oct;33(4):328-336. doi: 10.1007/s12928-017-0488-3. Epub 2017 Sep 5. Erratum in: Cardiovasc Interv Ther. 2018 Oct;33(4):337.


Response to Lee et al.

Feller-Kopman D, Liu S, Geisler BP, DeCamp MM, Pietzsch JB.

J Thorac Oncol. 2017 Sep;12(9):e152-e153. doi: 10.1016/j.jtho.2017.07.002. No abstract available.


Technetium-99m based small molecule radiopharmaceuticals and radiotracers targeting inflammation and infection.

Kniess T, Laube M, Wüst F, Pietzsch J.

Dalton Trans. 2017 Oct 31;46(42):14435-14451. doi: 10.1039/c7dt01735a. Review.


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