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Items: 1 to 20 of 39

1.

TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.

Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J.

Blood. 2019 Aug 29;134(9):727-740. doi: 10.1182/blood.2019000200. Epub 2019 Jul 16.

2.

PI3 kinase alpha and delta promote hematopoietic stem cell activation.

Hemmati S, Sinclair T, Tong M, Bartholdy B, Okabe RO, Ames K, Ostrodka L, Haque T, Kaur I, Mills TS, Agarwal A, Pietras EM, Zhao JJ, Roberts TM, Gritsman K.

JCI Insight. 2019 May 23;5. pii: 125832. doi: 10.1172/jci.insight.125832.

3.

Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.

Hernandez G, Mills TS, Rabe JL, Chavez JS, Kuldanek S, Kirkpatrick G, Noetzli L, Jubair WK, Zanche M, Meyers JR, Stevens BM, Fleenor CJ, Adane B, Dinarello CA, Ashton J, Jordan CT, Di Paola J, Hagman JR, Holers VM, Kuhn KA, Pietras EM.

Haematologica. 2019 May 17. pii: haematol.2018.197210. doi: 10.3324/haematol.2018.197210. [Epub ahead of print]

4.

A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy.

Tiessen I, Abildgaard MH, Lubas M, Gylling HM, Steinhauer C, Pietras EJ, Diederichs S, Frankel LB, Lund AH.

Oncogene. 2019 Jun;38(26):5127-5141. doi: 10.1038/s41388-019-0783-9. Epub 2019 Mar 14.

PMID:
30872794
5.

Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling.

Pollyea DA, Harris C, Rabe JL, Hedin BR, De Arras L, Katz S, Wheeler E, Bejar R, Walter MJ, Jordan CT, Pietras EM, Alper S.

Haematologica. 2019 Sep;104(9):e388-e392. doi: 10.3324/haematol.2018.214155. Epub 2019 Mar 7. No abstract available.

6.

Hematopoietic Stem Cells Rock Around The Clock: Circadian Fate Control via TNF/ROS Signals.

Chavez JS, Pietras EM.

Cell Stem Cell. 2018 Oct 4;23(4):459-460. doi: 10.1016/j.stem.2018.09.002.

7.

Zinc Finger Protein 521 Regulates Early Hematopoiesis through Cell-Extrinsic Mechanisms in the Bone Marrow Microenvironment.

Fleenor CJ, Arends T, Lei H, Åhsberg J, Okuyama K, Kuruvilla J, Cristobal S, Rabe JL, Pandey A, Danhorn T, Straign D, Espinosa JM, Warming S, Pietras EM, Sigvardsson M, Hagman JR.

Mol Cell Biol. 2018 Aug 15;38(17). pii: e00603-17. doi: 10.1128/MCB.00603-17. Print 2018 Sep 1.

8.

Ezh2 spares KitL from the cutter.

Pietras EM.

Blood. 2018 May 17;131(20):2180-2181. doi: 10.1182/blood-2018-04-841890. No abstract available.

PMID:
29773542
9.

Analysis of Murine Hematopoietic Stem Cell Proliferation During Inflammation.

Jalbert E, Pietras EM.

Methods Mol Biol. 2018;1686:183-200. doi: 10.1007/978-1-4939-7371-2_14.

PMID:
29030822
10.

Inflammation: a key regulator of hematopoietic stem cell fate in health and disease.

Pietras EM.

Blood. 2017 Oct 12;130(15):1693-1698. doi: 10.1182/blood-2017-06-780882. Epub 2017 Sep 5. Review.

11.

CD44 Interacts with HIF-2α to Modulate the Hypoxic Phenotype of Perinecrotic and Perivascular Glioma Cells.

Johansson E, Grassi ES, Pantazopoulou V, Tong B, Lindgren D, Berg TJ, Pietras EJ, Axelson H, Pietras A.

Cell Rep. 2017 Aug 15;20(7):1641-1653. doi: 10.1016/j.celrep.2017.07.049.

12.

The importance of tying up loose (DNA) ends.

Pietras EM.

Blood. 2017 May 4;129(18):2457-2458. doi: 10.1182/blood-2017-03-773184. No abstract available.

13.

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Hérault A, Binnewies M, Leong S, Calero-Nieto FJ, Zhang SY, Kang YA, Wang X, Pietras EM, Chu SH, Barry-Holson K, Armstrong S, Göttgens B, Passegué E.

Nature. 2017 Apr 6;544(7648):53-58. doi: 10.1038/nature21693. Epub 2017 Mar 29.

14.

ISSLS PRIZE IN BASIC SCIENCE 2017: Intervertebral disc/bone marrow cross-talk with Modic changes.

Dudli S, Sing DC, Hu SS, Berven SH, Burch S, Deviren V, Cheng I, Tay BKB, Alamin TF, Ith MAM, Pietras EM, Lotz JC.

Eur Spine J. 2017 May;26(5):1362-1373. doi: 10.1007/s00586-017-4955-4. Epub 2017 Jan 31.

15.

High-Throughput siRNA Screening Applied to the Ubiquitin-Proteasome System.

Poulsen EG, Nielsen SV, Pietras EJ, Johansen JV, Steinhauer C, Hartmann-Petersen R.

Methods Mol Biol. 2016;1449:421-39. doi: 10.1007/978-1-4939-3756-1_28.

PMID:
27613054
16.

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.

Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CP, Techner JM, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E.

Nat Cell Biol. 2016 Jun;18(6):607-18. doi: 10.1038/ncb3346. Epub 2016 Apr 25.

17.

Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions.

Pietras EM, Reynaud D, Kang YA, Carlin D, Calero-Nieto FJ, Leavitt AD, Stuart JM, Göttgens B, Passegué E.

Cell Stem Cell. 2015 Jul 2;17(1):35-46. doi: 10.1016/j.stem.2015.05.003. Epub 2015 Jun 18.

18.

Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis.

Mirantes C, Passegué E, Pietras EM.

Exp Cell Res. 2014 Dec 10;329(2):248-54. doi: 10.1016/j.yexcr.2014.08.017. Epub 2014 Aug 19. Review.

19.

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.

Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, Méndez J, Morrison CG, Passegué E.

Nature. 2014 Aug 14;512(7513):198-202. doi: 10.1038/nature13619. Epub 2014 Jul 30.

20.

Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons.

Pietras EM, Lakshminarasimhan R, Techner JM, Fong S, Flach J, Binnewies M, Passegué E.

J Exp Med. 2014 Feb 10;211(2):245-62. doi: 10.1084/jem.20131043. Epub 2014 Feb 3.

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