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Items: 4


GEMC1 is a critical regulator of multiciliated cell differentiation.

Terré B, Piergiovanni G, Segura-Bayona S, Gil-Gómez G, Youssef SA, Attolini CS, Wilsch-Bräuninger M, Jung C, Rojas AM, Marjanović M, Knobel PA, Palenzuela L, López-Rovira T, Forrow S, Huttner WB, Valverde MA, de Bruin A, Costanzo V, Stracker TH.

EMBO J. 2016 May 2;35(9):942-60. doi: 10.15252/embj.201592821. Epub 2016 Mar 1.


Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε.

Puddu F, Piergiovanni G, Plevani P, Muzi-Falconi M.

PLoS Genet. 2011 Mar;7(3):e1002022. doi: 10.1371/journal.pgen.1002022. Epub 2011 Mar 17.


GEMC1 is a novel TopBP1-interacting protein involved in chromosomal DNA replication.

Piergiovanni G, Costanzo V.

Cell Cycle. 2010 Sep 15;9(18):3662-6. Epub 2010 Sep 16.


Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint.

Puddu F, Granata M, Di Nola L, Balestrini A, Piergiovanni G, Lazzaro F, Giannattasio M, Plevani P, Muzi-Falconi M.

Mol Cell Biol. 2008 Aug;28(15):4782-93. doi: 10.1128/MCB.00330-08. Epub 2008 Jun 9.

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