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Items: 28

1.

Massive benthic litter funnelled to deep sea by flash-flood generated hyperpycnal flows.

Pierdomenico M, Casalbore D, Chiocci FL.

Sci Rep. 2019 Mar 29;9(1):5330. doi: 10.1038/s41598-019-41816-8.

2.

Transcription Factor ZNF281: A Novel Player in Intestinal Inflammation and Fibrosis.

Pierdomenico M, Palone F, Cesi V, Vitali R, Mancuso AB, Cucchiara S, Oliva S, Aloi M, Stronati L.

Front Immunol. 2018 Dec 11;9:2907. doi: 10.3389/fimmu.2018.02907. eCollection 2018.

3.

Krill oil, vitamin D and Lactobacillus reuteri cooperate to reduce gut inflammation.

Costanzo M, Cesi V, Palone F, Pierdomenico M, Colantoni E, Leter B, Vitali R, Negroni A, Cucchiara S, Stronati L.

Benef Microbes. 2018 Apr 25;9(3):389-399. doi: 10.3920/BM2017.0078. Epub 2018 Apr 10.

PMID:
29633636
4.

NOD2 and inflammation: current insights.

Negroni A, Pierdomenico M, Cucchiara S, Stronati L.

J Inflamm Res. 2018 Feb 12;11:49-60. doi: 10.2147/JIR.S137606. eCollection 2018. Review.

5.

RIP3 AND pMLKL promote necroptosis-induced inflammation and alter membrane permeability in intestinal epithelial cells.

Negroni A, Colantoni E, Pierdomenico M, Palone F, Costanzo M, Oliva S, Tiberti A, Cucchiara S, Stronati L.

Dig Liver Dis. 2017 Nov;49(11):1201-1210. doi: 10.1016/j.dld.2017.08.017. Epub 2017 Aug 10.

PMID:
28844856
6.

NOD2 induces autophagy to control AIEC bacteria infectiveness in intestinal epithelial cells.

Negroni A, Colantoni E, Vitali R, Palone F, Pierdomenico M, Costanzo M, Cesi V, Cucchiara S, Stronati L.

Inflamm Res. 2016 Oct;65(10):803-13. doi: 10.1007/s00011-016-0964-8. Epub 2016 Jun 22.

PMID:
27335178
7.

The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase.

Haile PA, Votta BJ, Marquis RW, Bury MJ, Mehlmann JF, Singhaus R Jr, Charnley AK, Lakdawala AS, Convery MA, Lipshutz DB, Desai BM, Swift B, Capriotti CA, Berger SB, Mahajan MK, Reilly MA, Rivera EJ, Sun HH, Nagilla R, Beal AM, Finger JN, Cook MN, King BW, Ouellette MT, Totoritis RD, Pierdomenico M, Negroni A, Stronati L, Cucchiara S, Ziółkowski B, Vossenkämper A, MacDonald TT, Gough PJ, Bertin J, Casillas LN.

J Med Chem. 2016 May 26;59(10):4867-80. doi: 10.1021/acs.jmedchem.6b00211. Epub 2016 May 4.

PMID:
27109867
8.

NOD2 Is Regulated By Mir-320 in Physiological Conditions but this Control Is Altered in Inflamed Tissues of Patients with Inflammatory Bowel Disease.

Pierdomenico M, Cesi V, Cucchiara S, Vitali R, Prete E, Costanzo M, Aloi M, Oliva S, Stronati L.

Inflamm Bowel Dis. 2016 Feb;22(2):315-26. doi: 10.1097/MIB.0000000000000659.

PMID:
26752466
9.

Dipotassium glycyrrhizate via HMGB1 or AMPK signaling suppresses oxidative stress during intestinal inflammation.

Vitali R, Palone F, Pierdomenico M, Negroni A, Cucchiara S, Aloi M, Oliva S, Stronati L.

Biochem Pharmacol. 2015 Oct 1;97(3):292-9. doi: 10.1016/j.bcp.2015.07.039. Epub 2015 Aug 5.

PMID:
26253686
10.

Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice.

Thakker DR, Sankaranarayanan S, Weatherspoon MR, Harrison J, Pierdomenico M, Heisel JM, Thompson LA, Haskell R, Grace JE, Taylor SJ, Albright CF, Shafer LL.

J Neurosci. 2015 Apr 29;35(17):6931-6. doi: 10.1523/JNEUROSCI.2262-14.2015.

11.

Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.

Toyn JH, Thompson LA, Lentz KA, Meredith JE Jr, Burton CR, Sankaranararyanan S, Guss V, Hall T, Iben LG, Krause CM, Krause R, Lin XA, Pierdomenico M, Polson C, Robertson AS, Denton RR, Grace JE, Morrison J, Raybon J, Zhuo X, Snow K, Padmanabha R, Agler M, Esposito K, Harden D, Prack M, Varma S, Wong V, Zhu Y, Zvyaga T, Gerritz S, Marcin LR, Higgins MA, Shi J, Wei C, Cantone JL, Drexler DM, Macor JE, Olson RE, Ahlijanian MK, Albright CF.

Int J Alzheimers Dis. 2014;2014:431858. doi: 10.1155/2014/431858. Epub 2014 Jul 8.

12.

Role of HMGB1 as a suitable biomarker of subclinical intestinal inflammation and mucosal healing in patients with inflammatory bowel disease.

Palone F, Vitali R, Cucchiara S, Pierdomenico M, Negroni A, Aloi M, Nuti F, Felice C, Armuzzi A, Stronati L.

Inflamm Bowel Dis. 2014 Aug;20(8):1448-57. doi: 10.1097/MIB.0000000000000113.

PMID:
24983978
13.

Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation.

Pierdomenico M, Negroni A, Stronati L, Vitali R, Prete E, Bertin J, Gough PJ, Aloi M, Cucchiara S.

Am J Gastroenterol. 2014 Feb;109(2):279-87. doi: 10.1038/ajg.2013.403. Epub 2013 Dec 10.

PMID:
24322838
14.

Mapping histologic patchiness of celiac disease by push enteroscopy.

Valitutti F, Di Nardo G, Barbato M, Aloi M, Celletti I, Trovato CM, Pierdomenico M, Marcheggiano A, Cucchiara S.

Gastrointest Endosc. 2014 Jan;79(1):95-100. doi: 10.1016/j.gie.2013.06.012. Epub 2013 Jul 22.

PMID:
23886355
15.

Presenting features and disease course of pediatric ulcerative colitis.

Aloi M, D'Arcangelo G, Pofi F, Vassallo F, Rizzo V, Nuti F, Di Nardo G, Pierdomenico M, Viola F, Cucchiara S.

J Crohns Colitis. 2013 Dec;7(11):e509-15. doi: 10.1016/j.crohns.2013.03.007. Epub 2013 Apr 11.

PMID:
23583691
16.

Characterization of adherent-invasive Escherichia coli isolated from pediatric patients with inflammatory bowel disease.

Negroni A, Costanzo M, Vitali R, Superti F, Bertuccini L, Tinari A, Minelli F, Di Nardo G, Nuti F, Pierdomenico M, Cucchiara S, Stronati L.

Inflamm Bowel Dis. 2012 May;18(5):913-24. doi: 10.1002/ibd.21899. Epub 2011 Oct 12.

PMID:
21994005
17.

Fecal HMGB1 is a novel marker of intestinal mucosal inflammation in pediatric inflammatory bowel disease.

Vitali R, Stronati L, Negroni A, Di Nardo G, Pierdomenico M, del Giudice E, Rossi P, Cucchiara S.

Am J Gastroenterol. 2011 Nov;106(11):2029-40. doi: 10.1038/ajg.2011.231. Epub 2011 Jul 26.

PMID:
21788990
18.

New insights into the pathogenesis of inflammatory bowel disease: transcription factors analysis in bioptic tissues from pediatric patients.

Pierdomenico M, Stronati L, Costanzo M, Vitali R, Di Nardo G, Nuti F, Oliva S, Cucchiara S, Negroni A.

J Pediatr Gastroenterol Nutr. 2011 Mar;52(3):271-9. doi: 10.1097/MPG.0b013e3182034d08.

PMID:
21336161
19.

Altered expression of innate immunity genes in different intestinal sites of children with ulcerative colitis.

Stronati L, Negroni A, Pierdomenico M, D'Ottavio C, Tirindelli D, Di Nardo G, Oliva S, Viola F, Cucchiara S.

Dig Liver Dis. 2010 Dec;42(12):848-53. doi: 10.1016/j.dld.2010.04.003. Epub 2010 May 7.

PMID:
20452301
20.

Activation of NOD2-mediated intestinal pathway in a pediatric population with Crohn's disease.

Negroni A, Stronati L, Pierdomenico M, Tirindelli D, Di Nardo G, Mancini V, Maiella G, Cucchiara S.

Inflamm Bowel Dis. 2009 Aug;15(8):1145-54. doi: 10.1002/ibd.20907.

PMID:
19266573
21.

Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer.

Mancuso M, Gallo D, Leonardi S, Pierdomenico M, Pasquali E, De Stefano I, Rebessi S, Tanori M, Scambia G, Di Majo V, Covelli V, Pazzaglia S, Saran A.

Carcinogenesis. 2009 Feb;30(2):340-7. doi: 10.1093/carcin/bgn243. Epub 2008 Oct 24.

PMID:
18952596
22.

The amyloid-beta rise and gamma-secretase inhibitor potency depend on the level of substrate expression.

Burton CR, Meredith JE, Barten DM, Goldstein ME, Krause CM, Kieras CJ, Sisk L, Iben LG, Polson C, Thompson MW, Lin XA, Corsa J, Fiedler T, Pierdomenico M, Cao Y, Roach AH, Cantone JL, Ford MJ, Drexler DM, Olson RE, Yang MG, Bergstrom CP, McElhone KE, Bronson JJ, Macor JE, Blat Y, Grafstrom RH, Stern AM, Seiffert DA, Zaczek R, Albright CF, Toyn JH.

J Biol Chem. 2008 Aug 22;283(34):22992-3003. doi: 10.1074/jbc.M804175200. Epub 2008 Jun 23.

23.

P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.

Meredith JE Jr, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D, Fiedler T, Lentz KA, Grace JE Jr, Kolb J, Corsa J, Pierdomenico M, Jones K, Olson RE, Macor JE, Albright CF.

J Pharmacol Exp Ther. 2008 Aug;326(2):502-13. doi: 10.1124/jpet.108.138974. Epub 2008 May 22.

PMID:
18499745
24.

Ex vivo occupancy of gamma-secretase inhibitors correlates with brain beta-amyloid peptide reduction in Tg2576 mice.

Goldstein ME, Cao Y, Fiedler T, Toyn J, Iben L, Barten DM, Pierdomenico M, Corsa J, Prasad CV, Olson RE, Li YW, Zaczek R, Albright CF.

J Pharmacol Exp Ther. 2007 Oct;323(1):102-8. Epub 2007 Jul 19.

PMID:
17640949
25.

Hair cycle-dependent basal cell carcinoma tumorigenesis in Ptc1neo67/+ mice exposed to radiation.

Mancuso M, Leonardi S, Tanori M, Pasquali E, Pierdomenico M, Rebessi S, Di Majo V, Covelli V, Pazzaglia S, Saran A.

Cancer Res. 2006 Jul 1;66(13):6606-14.

26.

Receptor occupancy of nonpeptide corticotropin-releasing factor 1 antagonist DMP696: correlation with drug exposure and anxiolytic efficacy.

Li YW, Hill G, Wong H, Kelly N, Ward K, Pierdomenico M, Ren S, Gilligan P, Grossman S, Trainor G, Taub R, McElroy J, Zazcek R.

J Pharmacol Exp Ther. 2003 Apr;305(1):86-96.

PMID:
12649356
27.

Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)-9(10H)-anthracenone: comparison to linopirdine.

Zaczek R, Chorvat RJ, Saye JA, Pierdomenico ME, Maciag CM, Logue AR, Fisher BN, Rominger DH, Earl RA.

J Pharmacol Exp Ther. 1998 May;285(2):724-30.

PMID:
9580619
28.

[Solitary perforated diverticulum of the right colon. Five cases].

Di Pierdomenico M, Sarro G, Grimi M, Bergamini C, Nanni G, Zanoni E, Garbini A, Luchetti P, Cattaneo A, Bragherio G.

Minerva Chir. 1992 Dec;47(23-24):1823-6. Italian.

PMID:
1289758

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