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Items: 1 to 50 of 67


Species-specific consequences of an E40K missense mutation in superoxide dismutase 1 (SOD1).

Draper ACE, Wilson Z, Maile C, Faccenda D, Campanella M, Piercy RJ.

FASEB J. 2020 Jan;34(1):458-473. doi: 10.1096/fj.201901455R. Epub 2019 Nov 25.


Assessing pathological changes within the nucleus ambiguus of horses with recurrent laryngeal neuropathy: An extreme, length-dependent axonopathy.

Draper ACE, Cahalan SD, Goodwin D, Perkins J, Piercy RJ.

Muscle Nerve. 2019 Dec;60(6):762-768. doi: 10.1002/mus.26699. Epub 2019 Oct 9.


Ex vivo investigation of the effect of the transverse arytenoid ligament on abduction of the arytenoid cartilage when performing equine laryngoplasty.

Chesworth M, Brandenberger O, Cheetham J, Windley Z, Schumacher J, Cochran K, Piercy RJ, Perkins JD.

N Z Vet J. 2019 Sep;67(5):264-269. doi: 10.1080/00480169.2019.1635538.


Energy turnover in mammalian skeletal muscle in contractions mimicking locomotion: effects of stimulus pattern on work, impulse and energetic cost and efficiency.

Curtin NA, Woledge RC, West TG, Goodwin D, Piercy RJ, Wilson AM.

J Exp Biol. 2019 Jul 10;222(Pt 13). pii: jeb203877. doi: 10.1242/jeb.203877.


Identification and validation of genetic variants predictive of gait in standardbred horses.

McCoy AM, Beeson SK, Rubin CJ, Andersson L, Caputo P, Lykkjen S, Moore A, Piercy RJ, Mickelson JR, McCue ME.

PLoS Genet. 2019 May 28;15(5):e1008146. doi: 10.1371/journal.pgen.1008146. eCollection 2019 May.


Functional electrical stimulation following nerve injury in a large animal model.

Cercone M, Jarvis JC, Ducharme NG, Perkins J, Piercy RJ, Willand MP, Mitchell LM, Sledziona M, Soderholm L, Cheetham J.

Muscle Nerve. 2019 Jun;59(6):717-725. doi: 10.1002/mus.26460. Epub 2019 Mar 25.


Asymmetric recurrent laryngeal nerve conduction velocities and dorsal cricoarytenoid muscle electromyographic characteristics in clinically normal horses.

Cercone M, Hokanson CM, Olsen E, Ducharme NG, Mitchell LM, Piercy RJ, Cheetham J.

Sci Rep. 2019 Feb 25;9(1):2713. doi: 10.1038/s41598-019-39189-z.


Atypical myopathy-associated hypoglycin A toxin remains in sycamore seedlings despite mowing, herbicidal spraying or storage in hay and silage.

González-Medina S, Montesso F, Chang YM, Hyde C, Piercy RJ.

Equine Vet J. 2019 Sep;51(5):701-704. doi: 10.1111/evj.13070. Epub 2019 Jan 30.


Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy.

Amoasii L, Hildyard JCW, Li H, Sanchez-Ortiz E, Mireault A, Caballero D, Harron R, Stathopoulou TR, Massey C, Shelton JM, Bassel-Duby R, Piercy RJ, Olson EN.

Science. 2018 Oct 5;362(6410):86-91. doi: 10.1126/science.aau1549. Epub 2018 Aug 30.


Detection of equine atypical myopathy-associated hypoglycin A in plant material: Optimisation and validation of a novel LC-MS based method without derivatisation.

González Medina S, Hyde C, Lovera I, Piercy RJ.

PLoS One. 2018 Jul 3;13(7):e0199521. doi: 10.1371/journal.pone.0199521. eCollection 2018.


Pathological classification of equine recurrent laryngeal neuropathy.

Draper ACE, Piercy RJ.

J Vet Intern Med. 2018 Jul;32(4):1397-1409. doi: 10.1111/jvim.15142. Epub 2018 Apr 24. Review.


Determination of qPCR Reference Genes Suitable for Normalizing Gene Expression in a Canine Model of Duchenne Muscular Dystrophy.

Hildyard JCW, Taylor-Brown F, Massey C, Wells DJ, Piercy RJ.

J Neuromuscul Dis. 2018;5(2):177-191. doi: 10.3233/JND-170267.


Kinematic discrimination of ataxia in horses is facilitated by blindfolding.

Olsen E, FouchÉ N, Jordan H, Pfau T, Piercy RJ.

Equine Vet J. 2018 Mar;50(2):166-171. doi: 10.1111/evj.12737. Epub 2017 Sep 13.


Equine atypical myopathy in the UK: Epidemiological characteristics of cases reported from 2011 to 2015 and factors associated with survival.

González-Medina S, Ireland JL, Piercy RJ, Newton JR, Votion DM.

Equine Vet J. 2017 Nov;49(6):746-752. doi: 10.1111/evj.12694. Epub 2017 Jun 19.


Whole genome sequencing reveals a 7 base-pair deletion in DMD exon 42 in a dog with muscular dystrophy.

Nghiem PP, Bello L, Balog-Alvarez C, López SM, Bettis A, Barnett H, Hernandez B, Schatzberg SJ, Piercy RJ, Kornegay JN.

Mamm Genome. 2017 Apr;28(3-4):106-113. doi: 10.1007/s00335-016-9675-2. Epub 2016 Dec 27.


Progressive Structural Defects in Canine Centronuclear Myopathy Indicate a Role for HACD1 in Maintaining Skeletal Muscle Membrane Systems.

Walmsley GL, Blot S, Venner K, Sewry C, Laporte J, Blondelle J, Barthélémy I, Maurer M, Blanchard-Gutton N, Pilot-Storck F, Tiret L, Piercy RJ.

Am J Pathol. 2017 Feb;187(2):441-456. doi: 10.1016/j.ajpath.2016.10.002. Epub 2016 Dec 8.


A highly prevalent equine glycogen storage disease is explained by constitutive activation of a mutant glycogen synthase.

Maile CA, Hingst JR, Mahalingan KK, O'Reilly AO, Cleasby ME, Mickelson JR, McCue ME, Anderson SM, Hurley TD, Wojtaszewski JFP, Piercy RJ.

Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3388-3398. doi: 10.1016/j.bbagen.2016.08.021. Epub 2016 Aug 31.


Heritability of Recurrent Exertional Rhabdomyolysis in Standardbred and Thoroughbred Racehorses Derived From SNP Genotyping Data.

Norton EM, Mickelson JR, Binns MM, Blott SC, Caputo P, Isgren CM, McCoy AM, Moore A, Piercy RJ, Swinburne JE, Vaudin M, McCue ME.

J Hered. 2016 Nov;107(6):537-43. doi: 10.1093/jhered/esw042. Epub 2016 Aug 3.


Dantrolene as a possible prophylactic treatment for RYR1-related rhabdomyolysis.

Scalco RS, Voermans NC, Piercy RJ, Jungbluth H, Quinlivan R.

Eur J Neurol. 2016 Aug;23(8):e56-7. doi: 10.1111/ene.13051. No abstract available.


Clinical research: developing an appropriate career structure.

Mellanby RJ, Price J, Wooldridge L, Jonsson NN, Clegg PD, Emes RD, England G, Corr SA, Piercy RJ, Mulcahy G, Wood JL, Walker BR, Argyle DJ.

Vet Rec. 2015 Nov 28;177(21):544-7. doi: 10.1136/vr.h6169. No abstract available.


Effects of Functional Electrical Stimulation on Denervated Laryngeal Muscle in a Large Animal Model.

Cheetham J, Perkins JD, Jarvis JC, Cercone M, Maw M, Hermanson JW, Mitchell LM, Piercy RJ, Ducharme NG.

Artif Organs. 2015 Oct;39(10):876-85. doi: 10.1111/aor.12624.


Ultrasonography detects early laryngeal muscle atrophy in an equine neurectomy model.

Chalmers HJ, Caswell J, Perkins J, Goodwin D, Viel L, Ducharme NG, Piercy RJ.

Muscle Nerve. 2016 Apr;53(4):583-92. doi: 10.1002/mus.24785.


HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth.

Blondelle J, Ohno Y, Gache V, Guyot S, Storck S, Blanchard-Gutton N, Barthélémy I, Walmsley G, Rahier A, Gadin S, Maurer M, Guillaud L, Prola A, Ferry A, Aubin-Houzelstein G, Demarquoy J, Relaix F, Piercy RJ, Blot S, Kihara A, Tiret L, Pilot-Storck F.

J Mol Cell Biol. 2015 Oct;7(5):429-40. doi: 10.1093/jmcb/mjv049. Epub 2015 Jul 9.


Development of a clonal equine myoblast cell line capable of terminal differentiation into mature myotubes in vitro.

Naylor RJ, Piercy RJ.

Am J Vet Res. 2015 Jul;76(7):608-14. doi: 10.2460/ajvr.76.7.608.


Histopathological assessment of intrinsic laryngeal musculature in horses with dynamic laryngeal collapse.

Fjordbakk CT, Revold T, Goodwin D, Piercy RJ.

Equine Vet J. 2015 Sep;47(5):603-8. doi: 10.1111/evj.12357. Epub 2014 Nov 13.


Calcium homeostasis in myogenic differentiation factor 1 (MyoD)-transformed, virally-transduced, skin-derived equine myotubes.

Fernandez-Fuente M, Terracciano CM, Martin-Duque P, Brown SC, Vassaux G, Piercy RJ.

PLoS One. 2014 Aug 22;9(8):e105971. doi: 10.1371/journal.pone.0105971. eCollection 2014.


Severe systemic calciphylaxis in a young cat.

Anfinsen KP, Piercy RJ, Massey C, Smith KC, Kenny PJ, Garden OA.

J Vet Intern Med. 2014 Jul-Aug;28(4):1325-30. doi: 10.1111/jvim.12378. Epub 2014 Jun 5. No abstract available.


Rater agreement on gait assessment during neurologic examination of horses.

Olsen E, Dunkel B, Barker WH, Finding EJ, Perkins JD, Witte TH, Yates LJ, Andersen PH, Baiker K, Piercy RJ.

J Vet Intern Med. 2014 Mar-Apr;28(2):630-8. doi: 10.1111/jvim.12320. Epub 2014 Feb 24.


Adenovirus-mediated expression of myogenic differentiation factor 1 (MyoD) in equine and human dermal fibroblasts enables their conversion to caffeine-sensitive myotubes.

Fernandez-Fuente M, Martin-Duque P, Vassaux G, Brown SC, Muntoni F, Terracciano CM, Piercy RJ.

Neuromuscul Disord. 2014 Mar;24(3):250-8. doi: 10.1016/j.nmd.2013.11.009. Epub 2013 Nov 23.


Vacuolar myopathy in an adult Warmblood horse.

Massey CA, Walmsley GL, Gliddon TP, Piercy RJ.

Neuromuscul Disord. 2013 Jun;23(6):473-7. doi: 10.1016/j.nmd.2013.03.007. Epub 2013 Apr 23.


Genetic diversity in the modern horse illustrated from genome-wide SNP data.

Petersen JL, Mickelson JR, Cothran EG, Andersson LS, Axelsson J, Bailey E, Bannasch D, Binns MM, Borges AS, Brama P, da Câmara Machado A, Distl O, Felicetti M, Fox-Clipsham L, Graves KT, Guérin G, Haase B, Hasegawa T, Hemmann K, Hill EW, Leeb T, Lindgren G, Lohi H, Lopes MS, McGivney BA, Mikko S, Orr N, Penedo MC, Piercy RJ, Raekallio M, Rieder S, Røed KH, Silvestrelli M, Swinburne J, Tozaki T, Vaudin M, M Wade C, McCue ME.

PLoS One. 2013;8(1):e54997. doi: 10.1371/journal.pone.0054997. Epub 2013 Jan 30.


Genome-wide analysis reveals selection for important traits in domestic horse breeds.

Petersen JL, Mickelson JR, Rendahl AK, Valberg SJ, Andersson LS, Axelsson J, Bailey E, Bannasch D, Binns MM, Borges AS, Brama P, da Câmara Machado A, Capomaccio S, Cappelli K, Cothran EG, Distl O, Fox-Clipsham L, Graves KT, Guérin G, Haase B, Hasegawa T, Hemmann K, Hill EW, Leeb T, Lindgren G, Lohi H, Lopes MS, McGivney BA, Mikko S, Orr N, Penedo MC, Piercy RJ, Raekallio M, Rieder S, Røed KH, Swinburne J, Tozaki T, Vaudin M, Wade CM, McCue ME.

PLoS Genet. 2013;9(1):e1003211. doi: 10.1371/journal.pgen.1003211. Epub 2013 Jan 17.


Evaluation of cardiac phenotype in horses with type 1 polysaccharide storage myopathy.

Naylor RJ, Luis-Fuentes V, Livesey L, Mobley CB, Henke N, Brock K, Fernandez-Fuente M, Piercy RJ.

J Vet Intern Med. 2012 Nov-Dec;26(6):1464-9. doi: 10.1111/j.1939-1676.2012.00988.x. Epub 2012 Sep 15.


Allele copy number and underlying pathology are associated with subclinical severity in equine type 1 polysaccharide storage myopathy (PSSM1).

Naylor RJ, Livesey L, Schumacher J, Henke N, Massey C, Brock KV, Fernandez-Fuente M, Piercy RJ.

PLoS One. 2012;7(7):e42317. doi: 10.1371/journal.pone.0042317. Epub 2012 Jul 31.


European outbreaks of atypical myopathy in grazing equids (2006-2009): spatiotemporal distribution, history and clinical features.

van Galen G, Marcillaud Pitel C, Saegerman C, Patarin F, Amory H, Baily JD, Cassart D, Gerber V, Hahn C, Harris P, Keen JA, Kirschvink N, Lefere L, McGorum B, Muller JM, Picavet MT, Piercy RJ, Roscher K, Serteyn D, Unger L, van der Kolk JH, van Loon G, Verwilghen D, Westermann CM, Votion DM.

Equine Vet J. 2012 Sep;44(5):614-20. doi: 10.1111/j.2042-3306.2012.00556.x. Epub 2012 Mar 26.


European outbreaks of atypical myopathy in grazing horses (2006-2009): determination of indicators for risk and prognostic factors.

van Galen G, Saegerman C, Marcillaud Pitel C, Patarin F, Amory H, Baily JD, Cassart D, Gerber V, Hahn C, Harris P, Keen JA, Kirschvink N, Lefere L, McGorum B, Muller JM, Picavet MT, Piercy RJ, Roscher K, Serteyn D, Unger L, van der Kolk JH, van Loon G, Verwilghen D, Westermann CM, Votion DM.

Equine Vet J. 2012 Sep;44(5):621-5. doi: 10.1111/j.2042-3306.2012.00555.x. Epub 2012 Mar 13.


Novel diabetes mellitus treatment: mature canine insulin production by canine striated muscle through gene therapy.

Niessen SJ, Fernandez-Fuente M, Mahmoud A, Campbell SC, Aldibbiat A, Huggins C, Brown AE, Holder A, Piercy RJ, Catchpole B, Shaw JA, Church DB.

Domest Anim Endocrinol. 2012 Jul;43(1):16-25. doi: 10.1016/j.domaniend.2012.01.006. Epub 2012 Feb 21.


Standing CT and clinical progression of equine cholesterol granulomata.

Finding E, Fletcher N, Avella C, Naylor RJ, Volk HA, Weller R, Dunkel B, Piercy RJ.

Vet Rec. 2012 Mar;170(11):289. doi: 10.1136/vr.100537. Epub 2012 Mar 1. No abstract available.


Borna disease virus infection of a horse in Great Britain.

Priestnall SL, Schöniger S, Ivens PA, Eickmann M, Brachthäuser L, Kehr K, Tupper C, Piercy RJ, Menzies-Gow NJ, Herden C.

Vet Rec. 2011 Apr 9;168(14):380b. doi: 10.1136/vr.c6405. Epub 2011 Mar 2. No abstract available.


Multiple immunofluorescence labelling enables simultaneous identification of all mature fibre types in a single equine skeletal muscle cryosection.

Tulloch LK, Perkins JD, Piercy RJ.

Equine Vet J. 2011 Jul;43(4):500-3. doi: 10.1111/j.2042-3306.2010.00329.x. Epub 2011 Mar 4.


Estimated prevalence of the Type 1 Polysaccharide Storage Myopathy mutation in selected North American and European breeds.

McCue ME, Anderson SM, Valberg SJ, Piercy RJ, Barakzai SZ, Binns MM, Distl O, Penedo MC, Wagner ML, Mickelson JR.

Anim Genet. 2010 Dec;41 Suppl 2:145-9. doi: 10.1111/j.1365-2052.2010.02124.x.


The 3D anatomy of the cervical articular process joints in the horse and their topographical relationship to the spinal cord.

Claridge HA, Piercy RJ, Parry A, Weller R.

Equine Vet J. 2010 Nov;42(8):726-31. doi: 10.1111/j.2042-3306.2010.00114.x.


Retrospective analysis of post-mortem findings in 1,444 aged donkeys.

Morrow LD, Smith KC, Piercy RJ, du Toit N, Burden FA, Olmos G, Gregory NG, Verheyen KL.

J Comp Pathol. 2011 Feb-Apr;144(2-3):145-56. doi: 10.1016/j.jcpa.2010.08.005. Epub 2010 Sep 28.


Equine degenerative myeloencephalopathy in a horse in the UK.

Naylor RJ, Priestnall SL, Turk AC, Summers BA, Schöniger S, Piercy RJ.

Vet Rec. 2010 Sep 4;167(10):380-1. doi: 10.1136/vr.c3818. No abstract available.


Three-dimensional biomechanics of simulated laryngeal abduction in horses.

Perkins JD, Raffetto J, Thompson C, Weller R, Piercy RJ, Pfau T.

Am J Vet Res. 2010 Sep;71(9):1003-10. doi: 10.2460/ajvr.71.9.1003.


Epidemiology of exertional rhabdomyolysis susceptibility in standardbred horses reveals associated risk factors and underlying enhanced performance.

Isgren CM, Upjohn MM, Fernandez-Fuente M, Massey C, Pollott G, Verheyen KL, Piercy RJ.

PLoS One. 2010 Jul 14;5(7):e11594. doi: 10.1371/journal.pone.0011594.


Histopathology and computed tomography of age-associated degeneration of the equine temporohyoid joint.

Naylor RJ, Perkins JD, Allen S, Aldred J, Draper E, Patterson-Kane J, Piercy RJ.

Equine Vet J. 2010 Jul;42(5):425-30. doi: 10.1111/j.2042-3306.2010.00036.x.


A duchenne muscular dystrophy gene hot spot mutation in dystrophin-deficient cavalier king charles spaniels is amenable to exon 51 skipping.

Walmsley GL, Arechavala-Gomeza V, Fernandez-Fuente M, Burke MM, Nagel N, Holder A, Stanley R, Chandler K, Marks SL, Muntoni F, Shelton GD, Piercy RJ.

PLoS One. 2010 Jan 13;5(1):e8647. doi: 10.1371/journal.pone.0008647.


A glycogen synthase 1 mutation associated with equine polysaccharide storage myopathy and exertional rhabdomyolysis occurs in a variety of UK breeds.

Stanley RL, McCue ME, Valberg SJ, Mickelson JR, Mayhew IG, McGowan C, Hahn CN, Patterson-Kane JC, Piercy RJ.

Equine Vet J. 2009 Jul;41(6):597-601.


Inguinal herniation of the large colon in a cob gelding four weeks after castration.

Ivens PA, Piercy RJ, Eliashar E.

Vet Rec. 2009 Sep 26;165(13):380-1. No abstract available.


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