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Items: 23


Ret Signaling Is Required for Tooth Pulp Innervation during Organogenesis.

Donnelly CR, Shah AA, Suh EB, Pierchala BA.

J Dent Res. 2019 Jun;98(6):705-712. doi: 10.1177/0022034519837971. Epub 2019 Apr 8.


Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons.

Donnelly CR, Gabreski NA, Suh EB, Chowdhury M, Pierchala BA.

J Cell Biol. 2018 Sep 3;217(9):3237-3253. doi: 10.1083/jcb.201703120. Epub 2018 Jul 17.


Semaphorin3A Signaling Is Dispensable for Motor Axon Reinnervation of the Adult Neuromuscular Junction.

Shadrach JL, Pierchala BA.

eNeuro. 2018 May 16;5(3). pii: ENEURO.0155-17.2018. doi: 10.1523/ENEURO.0155-17.2018. eCollection 2018 May-Jun.


Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification.

Donnelly CR, Shah AA, Mistretta CM, Bradley RM, Pierchala BA.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E516-E525. doi: 10.1073/pnas.1708838115. Epub 2017 Dec 27.


p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling.

Chen Z, Donnelly CR, Dominguez B, Harada Y, Lin W, Halim AS, Bengoechea TG, Pierchala BA, Lee KF.

Cell Rep. 2017 Oct 17;21(3):707-720. doi: 10.1016/j.celrep.2017.09.037.


Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction.

Gabreski NA, Vaghasia JK, Novakova SS, McDonald NQ, Pierchala BA.

J Biol Chem. 2016 Jul 29;291(31):16249-62. doi: 10.1074/jbc.M115.709675. Epub 2016 May 23.


Semaphorin 3A is a retrograde cell death signal in developing sympathetic neurons.

Wehner AB, Abdesselem H, Dickendesher TL, Imai F, Yoshida Y, Giger RJ, Pierchala BA.

Development. 2016 May 1;143(9):1560-70. doi: 10.1242/dev.134627.


The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175(WT/HD) mice.

Wehner AB, Milen AM, Albin RL, Pierchala BA.

Neuroscience. 2016 Jun 2;324:297-306. doi: 10.1016/j.neuroscience.2016.02.069. Epub 2016 Mar 3.


Lipid Rafts Are Physiologic Membrane Microdomains Necessary for the Morphogenic and Developmental Functions of Glial Cell Line-Derived Neurotrophic Factor In Vivo.

Tsui CC, Gabreski NA, Hein SJ, Pierchala BA.

J Neurosci. 2015 Sep 23;35(38):13233-43. doi: 10.1523/JNEUROSCI.2935-14.2015.


Polarized expression of p75(NTR) specifies axons during development and adult neurogenesis.

Zuccaro E, Bergami M, Vignoli B, Bony G, Pierchala BA, Santi S, Cancedda L, Canossa M.

Cell Rep. 2014 Apr 10;7(1):138-52. doi: 10.1016/j.celrep.2014.02.039. Epub 2014 Mar 27.


CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.

Calco GN, Stephens OR, Donahue LM, Tsui CC, Pierchala BA.

J Biol Chem. 2014 Mar 14;289(11):7307-19. doi: 10.1074/jbc.M113.537878. Epub 2014 Jan 14.


Expression of axonal protein degradation machinery in sympathetic neurons is regulated by nerve growth factor.

Frampton JP, Guo C, Pierchala BA.

J Neurosci Res. 2012 Aug;90(8):1533-46. doi: 10.1002/jnr.23041. Epub 2012 Mar 13.


Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals.

Bonanomi D, Chivatakarn O, Bai G, Abdesselem H, Lettieri K, Marquardt T, Pierchala BA, Pfaff SL.

Cell. 2012 Feb 3;148(3):568-82. doi: 10.1016/j.cell.2012.01.024.


Proteomic analysis of the slit diaphragm complex: CLIC5 is a protein critical for podocyte morphology and function.

Pierchala BA, Muñoz MR, Tsui CC.

Kidney Int. 2010 Nov;78(9):868-82. doi: 10.1038/ki.2010.212. Epub 2010 Jul 21.


CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.

Tsui CC, Pierchala BA.

J Neurosci. 2008 Aug 27;28(35):8789-800. doi: 10.1523/JNEUROSCI.2738-08.2008.


NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation.

Pierchala BA, Tsui CC, Milbrandt J, Johnson EM.

J Neurochem. 2007 Mar;100(5):1169-76. Epub 2007 Jan 4.


Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells.

Lee CS, Tee LY, Dusenbery S, Takata T, Golden JP, Pierchala BA, Gottlieb DI, Johnson EM Jr, Choi DW, Snider BJ.

Exp Neurol. 2005 Jan;191(1):65-76.


An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons.

Riccio A, Pierchala BA, Ciarallo CL, Ginty DD.

Science. 1997 Aug 22;277(5329):1097-100.


The rapamycin and FKBP12 target (RAFT) displays phosphatidylinositol 4-kinase activity.

Sabatini DM, Pierchala BA, Barrow RK, Schell MJ, Snyder SH.

J Biol Chem. 1995 Sep 8;270(36):20875-8.

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