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Items: 1 to 50 of 153

1.

Understanding suicide among colleagues.

Pierce JH.

J Am Vet Med Assoc. 2015 Jun 1;246(11):1179. No abstract available.

PMID:
26164872
2.
3.

Activation of insulin-like growth factor I receptor signaling pathway is critical for mouse plasma cell tumor growth.

Li W, Hyun T, Heller M, Yam A, Flechner L, Pierce JH, Rudikoff S.

Cancer Res. 2000 Jul 15;60(14):3909-15.

4.

Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells.

Ahmad F, Cong LN, Stenson Holst L, Wang LM, Rahn Landstrom T, Pierce JH, Quon MJ, Degerman E, Manganiello VC.

J Immunol. 2000 May 1;164(9):4678-88.

5.

Protein kinase C-alpha overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawal.

Li W, Zhang J, Flechner L, Hyun T, Yam A, Franke TF, Pierce JH.

Oncogene. 1999 Nov 11;18(47):6564-72.

6.

Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase.

Harari D, Tzahar E, Romano J, Shelly M, Pierce JH, Andrews GC, Yarden Y.

Oncogene. 1999 Apr 29;18(17):2681-9.

7.

Insulin receptor substrate-1 enhances growth hormone-induced proliferation.

Liang L, Zhou T, Jiang J, Pierce JH, Gustafson TA, Frank SJ.

Endocrinology. 1999 May;140(5):1972-83.

PMID:
10218944
8.

Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression.

Soon L, Flechner L, Gutkind JS, Wang LH, Baserga R, Pierce JH, Li W.

Mol Cell Biol. 1999 May;19(5):3816-28.

9.
10.

IL-3 and IL-4 activate cyclic nucleotide phosphodiesterases 3 (PDE3) and 4 (PDE4) by different mechanisms in FDCP2 myeloid cells.

Ahmad F, Gao G, Wang LM, Landstrom TR, Degerman E, Pierce JH, Manganiello VC.

J Immunol. 1999 Apr 15;162(8):4864-75.

11.

cbl-b inhibits epidermal growth factor receptor signaling.

Ettenberg SA, Keane MM, Nau MM, Frankel M, Wang LM, Pierce JH, Lipkowitz S.

Oncogene. 1999 Mar 11;18(10):1855-66.

12.

Pathogenic poxviruses reveal viral strategies to exploit the ErbB signaling network.

Tzahar E, Moyer JD, Waterman H, Barbacci EG, Bao J, Levkowitz G, Shelly M, Strano S, Pinkas-Kramarski R, Pierce JH, Andrews GC, Yarden Y.

EMBO J. 1998 Oct 15;17(20):5948-63.

13.

NRG-3 in human breast cancers: activation of multiple erbB family proteins.

Hijazi MM, Young PE, Dougherty MK, Bressette DS, Cao TT, Pierce JH, Wong LM, Alimandi M, King CR.

Int J Oncol. 1998 Nov;13(5):1061-7.

PMID:
9772300
14.

The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling.

Myers MG Jr, Mendez R, Shi P, Pierce JH, Rhoads R, White MF.

J Biol Chem. 1998 Oct 9;273(41):26908-14.

15.

ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.

Pinkas-Kramarski R, Shelly M, Guarino BC, Wang LM, Lyass L, Alroy I, Alimandi M, Kuo A, Moyer JD, Lavi S, Eisenstein M, Ratzkin BJ, Seger R, Bacus SS, Pierce JH, Andrews GC, Yarden Y.

Mol Cell Biol. 1998 Oct;18(10):6090-101. Erratum in: Mol Cell Biol 1998 Dec;18(12):7602. Alamandi M [corrected to Alimandi M].

16.

Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation.

Li W, Jiang YX, Zhang J, Soon L, Flechner L, Kapoor V, Pierce JH, Wang LH.

Mol Cell Biol. 1998 Oct;18(10):5888-98.

17.

ErbB-4 ribozymes abolish neuregulin-induced mitogenesis.

Tang CK, Goldstein DJ, Payne J, Czubayko F, Alimandi M, Wang LM, Pierce JH, Lippman ME.

Cancer Res. 1998 Aug 1;58(15):3415-22.

18.

ErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4.

Wang LM, Kuo A, Alimandi M, Veri MC, Lee CC, Kapoor V, Ellmore N, Chen XH, Pierce JH.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6809-14.

19.

Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes.

Shelly M, Pinkas-Kramarski R, Guarino BC, Waterman H, Wang LM, Lyass L, Alimandi M, Kuo A, Bacus SS, Pierce JH, Andrews GC, Yarden Y.

J Biol Chem. 1998 Apr 24;273(17):10496-505.

20.

Recombinant heregulin-Pseudomonas exotoxin fusion proteins: interactions with the heregulin receptors and antitumor activity in vivo.

Yang D, Kuan CT, Payne J, Kihara A, Murray A, Wang LM, Alimandi M, Pierce JH, Pastan I, Lippman ME.

Clin Cancer Res. 1998 Apr;4(4):993-1004.

21.
22.

Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptors.

Alimandi M, Wang LM, Bottaro D, Lee CC, Kuo A, Frankel M, Fedi P, Tang C, Lippman M, Pierce JH.

EMBO J. 1997 Sep 15;16(18):5608-17.

23.
24.

PLC-gamma activation is required for PDGF-betaR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells.

Alimandi M, Heidaran MA, Gutkind JS, Zhang J, Ellmore N, Valius M, Kazlauskas A, Pierce JH, Li W.

Oncogene. 1997 Jul 31;15(5):585-93.

25.
26.

Characterization of a mast cell line that lacks the extracellular domain of membrane c-kit.

Mekori YA, Oh CK, Dastych J, Goff JP, Adachi S, Bianchine PJ, Worobec A, Semere T, Pierce JH, Metcalfe DD.

Immunology. 1997 Apr;90(4):518-25.

27.

Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules.

Chen XH, Patel BK, Wang LM, Frankel M, Ellmore N, Flavell RA, LaRochelle WJ, Pierce JH.

J Biol Chem. 1997 Mar 7;272(10):6556-60.

28.

The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

Sun XJ, Pons S, Wang LM, Zhang Y, Yenush L, Burks D, Myers MG Jr, Glasheen E, Copeland NG, Jenkins NA, Pierce JH, White MF.

Mol Endocrinol. 1997 Feb;11(2):251-62.

PMID:
9013772
29.

Oncogenic activation of the alphaPDGFR defines a domain that negatively regulates receptor dimerization.

Uren A, Yu JC, Karcaaltincaba M, Pierce JH, Heidaran MA.

Oncogene. 1997 Jan 16;14(2):157-62.

30.

Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells.

Welham MJ, Bone H, Levings M, Learmonth L, Wang LM, Leslie KB, Pierce JH, Schrader JW.

J Biol Chem. 1997 Jan 10;272(2):1377-81.

31.

The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway.

Cortez D, Stoica G, Pierce JH, Pendergast AM.

Oncogene. 1996 Dec 19;13(12):2589-94.

PMID:
9000132
32.

IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway.

Zamorano J, Wang HY, Wang LM, Pierce JH, Keegan AD.

J Immunol. 1996 Dec 1;157(11):4926-34.

PMID:
8943397
33.

Identification of tyrosine 187 as a protein kinase C-delta phosphorylation site.

Li W, Chen XH, Kelley CA, Alimandi M, Zhang J, Chen Q, Bottaro DP, Pierce JH.

J Biol Chem. 1996 Oct 18;271(42):26404-9.

34.

Stat6 and Jak1 are common elements in platelet-derived growth factor and interleukin-4 signal transduction pathways in NIH 3T3 fibroblasts.

Patel BK, Wang LM, Lee CC, Taylor WG, Pierce JH, LaRochelle WJ.

J Biol Chem. 1996 Sep 6;271(36):22175-82.

35.

Expression of an ATP binding mutant of PKC-delta inhibits Sis-induced transformation of NIH3T3 cells.

Li W, Michieli P, Alimandi M, Lorenzi MV, Wu Y, Wang LH, Heidaran MA, Pierce JH.

Oncogene. 1996 Aug 15;13(4):731-7.

PMID:
8761294
36.

YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.

Myers MG Jr, Zhang Y, Aldaz GA, Grammer T, Glasheen EM, Yenush L, Wang LM, Sun XJ, Blenis J, Pierce JH, White MF.

Mol Cell Biol. 1996 Aug;16(8):4147-55.

38.
39.

The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis.

Yenush L, Fernandez R, Myers MG Jr, Grammer TC, Sun XJ, Blenis J, Pierce JH, Schlessinger J, White MF.

Mol Cell Biol. 1996 May;16(5):2509-17.

40.

Inhibition of oncogene-mediated transformation by ectopic expression of p21Waf1 in NIH3T3 cells.

Michieli P, Li W, Lorenzi MV, Miki T, Zakut R, Givol D, Pierce JH.

Oncogene. 1996 Feb 15;12(4):775-84.

PMID:
8632899
41.

Isolation of the full-length murine erythropoietin receptor using a baculovirus expression system.

Spivak JL, Avedissian LS, Pierce JH, Williams D, Hankins WD, Jensen RA.

Blood. 1996 Feb 1;87(3):926-37.

42.

Protein kinase C-delta, an important signaling molecule in the platelet-derived growth factor beta receptor pathway.

Li W, Pierce JH.

Curr Top Microbiol Immunol. 1996;211:55-65. Review. No abstract available.

PMID:
8585964
43.

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases.

Johnston JA, Wang LM, Hanson EP, Sun XJ, White MF, Oakes SA, Pierce JH, O'Shea JJ.

J Biol Chem. 1995 Dec 1;270(48):28527-30.

44.

The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction.

Wang LM, Michieli P, Lie WR, Liu F, Lee CC, Minty A, Sun XJ, Levine A, White MF, Pierce JH.

Blood. 1995 Dec 1;86(11):4218-27.

45.
46.

Role of IRS-2 in insulin and cytokine signalling.

Sun XJ, Wang LM, Zhang Y, Yenush L, Myers MG Jr, Glasheen E, Lane WS, Pierce JH, White MF.

Nature. 1995 Sep 14;377(6545):173-7.

PMID:
7675087
47.

Interleukin 4 signals through two related pathways.

Pernis A, Witthuhn B, Keegan AD, Nelms K, Garfein E, Ihle JN, Paul WE, Pierce JH, Rothman P.

Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7971-5.

48.

Signal transduction through the IL-4 and insulin receptor families.

Wang LM, Keegan A, Frankel M, Paul WE, Pierce JH.

Stem Cells. 1995 Jul;13(4):360-8. Review.

PMID:
7549895
49.

Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.

Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JL, Pierce JH, Keegan AD, Nelms K, et al.

Mol Cell Biol. 1995 Jun;15(6):3336-43.

50.

The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling.

Myers MG Jr, Grammer TC, Brooks J, Glasheen EM, Wang LM, Sun XJ, Blenis J, Pierce JH, White MF.

J Biol Chem. 1995 May 19;270(20):11715-8.

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