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Armed and prohibited: characteristics of unlawful owners of legally purchased firearms.

Pear VA, McCort CD, Li Y, Beckett L, Tancredi D, Studdert DM, Kass PH, Pierce GL, Braga AA, Wright MA, Laqueur HS, Kravitz-Wirtz N, Wintemute GJ.

Inj Prev. 2020 Mar 10. pii: injuryprev-2019-043479. doi: 10.1136/injuryprev-2019-043479. [Epub ahead of print]


Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice.

Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL.

Hypertension. 2020 Feb;75(2):569-579. doi: 10.1161/HYPERTENSIONAHA.119.14056. Epub 2019 Dec 23.


Education moderates the effects of large central artery aging on cognitive performance in middle-aged and older adults.

DuBose LE, Moser DJ, Harlynn E, Fiedorowicz JG, Pierce GL.

Physiol Rep. 2019 Dec;7(23):e14291. doi: 10.14814/phy2.14291.


Anxiety, C-reactive protein, and obesity in NHANES 1999-2004.

Persons JE, Pierce GL, Fiedorowicz JG.

Heliyon. 2019 Aug 17;5(8):e02267. doi: 10.1016/j.heliyon.2019.e02267. eCollection 2019 Aug.


Cardiorespiratory fitness and hippocampal volume predict faster episodic associative learning in older adults.

Cole RC, Hazeltine E, Weng TB, Wharff C, DuBose LE, Schmid P, Sigurdsson G, Magnotta VA, Pierce GL, Voss MW.

Hippocampus. 2020 Feb;30(2):143-155. doi: 10.1002/hipo.23151. Epub 2019 Aug 28.


Acute Exercise Effects Predict Training Change in Cognition and Connectivity.

Voss MW, Weng TB, Narayana-Kumanan K, Cole RC, Wharff C, Reist L, Dubose L, Sigurdsson G, Mills JA, Long JD, Magnotta VA, Pierce GL.

Med Sci Sports Exerc. 2020 Jan;52(1):131-140. doi: 10.1249/MSS.0000000000002115.


Sex and age differences in the association between sympathetic outflow and central elastic artery wall thickness in humans.

Holwerda SW, Luehrs RE, DuBose LE, Majee R, Pierce GL.

Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H552-H560. doi: 10.1152/ajpheart.00275.2019. Epub 2019 Jul 5.


Response by Holwerda et al to Letter Regarding Article "Elevated Muscle Sympathetic Nerve Activity Contributes to Central Artery Stiffness in Young and Middle-Age/Older Adults".

Holwerda SW, Fadel PJ, Abboud FM, Pierce GL.

Hypertension. 2019 Aug;74(2):e33. doi: 10.1161/HYPERTENSIONAHA.119.13299. Epub 2019 Jun 24. No abstract available.


Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Protects From Angiotensin II-Induced Endothelial Dysfunction in Adult Offspring Born From Pregnancies Complicated by Hypertension.

Nair AR, Silva SD Jr, Agbor LN, Wu J, Nakagawa P, Mukohda M, Lu KT, Sandgren JA, Pierce GL, Santillan MK, Grobe JL, Sigmund CD.

Hypertension. 2019 Jul;74(1):173-183. doi: 10.1161/HYPERTENSIONAHA.119.13101. Epub 2019 May 20.


Elevated Muscle Sympathetic Nerve Activity Contributes to Central Artery Stiffness in Young and Middle-Age/Older Adults.

Holwerda SW, Luehrs RE, DuBose L, Collins MT, Wooldridge NA, Stroud AK, Fadel PJ, Abboud FM, Pierce GL.

Hypertension. 2019 May;73(5):1025-1035. doi: 10.1161/HYPERTENSIONAHA.118.12462. Erratum in: Hypertension. 2019 Jun;73(6):e122.


CT-Measured Lung Air-Trapping is Associated with Higher Carotid Artery Stiffness in Individuals with Chronic Obstructive Pulmonary Disease.

Luehrs RE, Newell JD Jr, Comellas AP, Hoffman EA, Warner K, Croghan A, DuBose LE, Nopoulos P, Magnotta V, Arndt S, Pierce GL, Hoth KF.

J Appl Physiol (1985). 2018 Oct 11. doi: 10.1152/japplphysiol.00580.2018. [Epub ahead of print]


Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice.

Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL.

JCI Insight. 2018 Oct 4;3(19). pii: 99403. doi: 10.1172/jci.insight.99403.


Higher Aortic Stiffness Is Associated With Lower Global Cerebrovascular Reserve Among Older Humans.

DuBose LE, Boles Ponto LL, Moser DJ, Harlynn E, Reierson L, Pierce GL.

Hypertension. 2018 Aug;72(2):476-482. doi: 10.1161/HYPERTENSIONAHA.118.11143. Epub 2018 Jun 18.


Initiating life-long aerobic exercise 4-5 days per week before or near age 50 years: is this the 'holy-grail' of preventing age-related central artery stiffness?

Pierce GL.

J Physiol. 2018 Jul;596(14):2635-2636. doi: 10.1113/JP276253. Epub 2018 Jun 21. No abstract available.


Femoral vascular conductance and peroneal muscle sympathetic nerve activity responses to acute epidural spinal cord stimulation in humans.

Holwerda SW, Holland MT, Reddy CG, Pierce GL.

Exp Physiol. 2018 Jun;103(6):905-915. doi: 10.1113/EP086945. Epub 2018 May 5.


Relative burst amplitude of muscle sympathetic nerve activity is an indicator of altered sympathetic outflow in chronic anxiety.

Holwerda SW, Luehrs RE, Gremaud AL, Wooldridge NA, Stroud AK, Fiedorowicz JG, Abboud FM, Pierce GL.

J Neurophysiol. 2018 Jul 1;120(1):11-22. doi: 10.1152/jn.00064.2018. Epub 2018 Mar 14.


Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia.

Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK.

Clin Sci (Lond). 2018 Feb 14;132(3):419-436. doi: 10.1042/CS20171059. Print 2018 Feb 14.


Angiotensin AT1A receptors expressed in vasopressin-producing cells of the supraoptic nucleus contribute to osmotic control of vasopressin.

Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R770-R780. doi: 10.1152/ajpregu.00435.2017. Epub 2018 Jan 24.


Bipolar disorder and related mood states are not associated with endothelial function of small arteries in adults without heart disease.

Tong B, Abosi O, Schmitz S, Myers J, Pierce GL, Fiedorowicz JG.

Gen Hosp Psychiatry. 2018 Mar - Apr;51:36-40. doi: 10.1016/j.genhosppsych.2017.12.005. Epub 2017 Dec 19.


Hemoglobin A1c and C-reactive protein are independently associated with blunted nocturnal blood pressure dipping in obesity-related prediabetes.

Lane-Cordova AD, Kalil GZ, Wagner CJ, Sindler AL, Fiedorowicz JG, Ajibewa T, Haynes WG, Pierce GL.

Hypertens Res. 2018 Jan;41(1):33-38. doi: 10.1038/hr.2017.82. Epub 2017 Oct 26.


Aortic Stiffness in Aging and Hypertension: Prevention and Treatment with Habitual Aerobic Exercise.

Pierce GL.

Curr Hypertens Rep. 2017 Oct 18;19(11):90. doi: 10.1007/s11906-017-0788-0. Review.


Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function.

Rossman MJ, Kaplon RE, Hill SD, McNamara MN, Santos-Parker JR, Pierce GL, Seals DR, Donato AJ.

Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H890-H895. doi: 10.1152/ajpheart.00416.2017. Epub 2017 Sep 29.


Mechanisms and Subclinical Consequences of Aortic Stiffness.

Pierce GL.

Hypertension. 2017 Nov;70(5):848-853. doi: 10.1161/HYPERTENSIONAHA.117.08933. Epub 2017 Sep 5. Review. No abstract available.


Muscle contraction induced arterial shear stress increases endothelial nitric oxide synthase phosphorylation in humans.

Casey DP, Ueda K, Wegman-Points L, Pierce GL.

Am J Physiol Heart Circ Physiol. 2017 Oct 1;313(4):H854-H859. doi: 10.1152/ajpheart.00282.2017. Epub 2017 Aug 11.


The Acute Effects of Aerobic Exercise on the Functional Connectivity of Human Brain Networks.

Weng TB, Pierce GL, Darling WG, Falk D, Magnotta VA, Voss MW.

Brain Plast. 2017 Mar 28;2(2):171-190. doi: 10.3233/BPL-160039.


Carotid β-stiffness index is associated with slower processing speed but not working memory or white matter integrity in healthy middle-aged/older adults.

DuBose LE, Voss MW, Weng TB, Kent JD, Dubishar KM, Lane-Cordova A, Sigurdsson G, Schmid P, Barlow PB, Pierce GL.

J Appl Physiol (1985). 2017 Apr 1;122(4):868-876. doi: 10.1152/japplphysiol.00769.2016. Epub 2017 Jan 26.


Anxiety independently contributes to elevated inflammation in humans with obesity.

Pierce GL, Kalil GZ, Ajibewa T, Holwerda SW, Persons J, Moser DJ, Fiedorowicz JG.

Obesity (Silver Spring). 2017 Feb;25(2):286-289. doi: 10.1002/oby.21698. Epub 2016 Dec 21.


Habitual aerobic exercise does not protect against micro- or macrovascular endothelial dysfunction in healthy estrogen-deficient postmenopausal women.

Santos-Parker JR, Strahler TR, Vorwald VM, Pierce GL, Seals DR.

J Appl Physiol (1985). 2017 Jan 1;122(1):11-19. doi: 10.1152/japplphysiol.00732.2016. Epub 2016 Nov 10.


Abnormal Central Pulsatile Hemodynamics in Adolescents With Obesity: Higher Aortic Forward Pressure Wave Amplitude Is Independently Associated With Greater Left Ventricular Mass.

Pierce GL, Pajaniappan M, DiPietro A, Darracott-Woei-A-Sack K, Kapuku GK.

Hypertension. 2016 Nov;68(5):1200-1207. Epub 2016 Sep 12.


High trans but not saturated fat beverage causes an acute reduction in postprandial vascular endothelial function but not arterial stiffness in humans.

Lane-Cordova AD, Witmer JR, Dubishar K, DuBose LE, Chenard CA, Siefers KJ, Myers JE, Points LJ, Pierce GL.

Vasc Med. 2016 Oct;21(5):429-436. Epub 2016 Aug 23.


Estimated aortic stiffness is independently associated with cardiac baroreflex sensitivity in humans: role of ageing and habitual endurance exercise.

Pierce GL, Harris SA, Seals DR, Casey DP, Barlow PB, Stauss HM.

J Hum Hypertens. 2016 Sep;30(9):513-20. doi: 10.1038/jhh.2016.3. Epub 2016 Feb 25.


Introduction to the American Heart Association's Hypertension Strategically Focused Research Network.

Muntner P, Becker RC, Calhoun D, Chen D, Cowley AW Jr, Flynn JT, Grobe JL, Kidambi S, Kotchen TA, Lackland DT, Leslie KK, Li Y, Liang M, Lloyd A, Mattson DL, Mendizabal B, Mitsnefes M, Nair A, Pierce GL, Pollock JS, Safford MM, Santillan MK, Sigmund CD, Thomas SJ, Urbina EM.

Hypertension. 2016 Apr;67(4):674-80. doi: 10.1161/HYPERTENSIONAHA.115.06433. Epub 2016 Feb 22. Review. No abstract available.


Higher augmentation index is associated with tension-type headache and migraine in middle-aged/older humans with obesity.

Kalil GZ, Recober A, Hoang-Tienor A, Bridget Zimmerman M, Haynes WG, Pierce GL.

Obesity (Silver Spring). 2016 Apr;24(4):865-70. doi: 10.1002/oby.21414. Epub 2016 Feb 5.


Myeloperoxidase is increased in human cerebral aneurysms and increases formation and rupture of cerebral aneurysms in mice.

Chu Y, Wilson K, Gu H, Wegman-Points L, Dooley SA, Pierce GL, Cheng G, Pena Silva RA, Heistad DD, Hasan D.

Stroke. 2015 Jun;46(6):1651-6. doi: 10.1161/STROKEAHA.114.008589. Epub 2015 Apr 28.


Vasopressin: the missing link for preeclampsia?

Sandgren JA, Scroggins SM, Santillan DA, Devor EJ, Gibson-Corley KN, Pierce GL, Sigmund CD, Santillan MK, Grobe JL.

Am J Physiol Regul Integr Comp Physiol. 2015 Nov 1;309(9):R1062-4. doi: 10.1152/ajpregu.00073.2015. Epub 2015 Mar 25. Review.


Novel role for endogenous hepatocyte growth factor in the pathogenesis of intracranial aneurysms.

Peña-Silva RA, Chalouhi N, Wegman-Points L, Ali M, Mitchell I, Pierce GL, Chu Y, Ballas ZK, Heistad D, Hasan D.

Hypertension. 2015 Mar;65(3):587-93. doi: 10.1161/HYPERTENSIONAHA.114.04681. Epub 2014 Dec 15.


Finger volume pulse waveforms facilitate reliable assessment of heart rate variability, but not blood pressure variability or baroreflex function.

Linder JR, Stauss HM, Gindes H, Pierce GL, Von Bergen NH, Haynes WG, Fiedorowicz JG.

BMC Cardiovasc Disord. 2014 Dec 9;14:180. doi: 10.1186/1471-2261-14-180.


The impact of age on vascular smooth muscle function in humans.

Montero D, Pierce GL, Stehouwer CD, Padilla J, Thijssen DH.

J Hypertens. 2015 Mar;33(3):445-53; discussion 453. doi: 10.1097/HJH.0000000000000446. Review.


Impact of California firearms sales laws and dealer regulations on the illegal diversion of guns.

Pierce GL, Braga AA, Wintemute GJ.

Inj Prev. 2015 Jun;21(3):179-84. doi: 10.1136/injuryprev-2014-041413. Epub 2014 Dec 3.


Differential Effects of Acute Exercise on Distinct Aspects of Executive Function.

Weng TB, Pierce GL, Darling WG, Voss MW.

Med Sci Sports Exerc. 2015 Jul;47(7):1460-9. doi: 10.1249/MSS.0000000000000542.


Cardiorespiratory fitness and the attenuation of age-related rise in blood pressure: an important role for effective primordial prevention.

Franklin SS, Pierce GL.

J Am Coll Cardiol. 2014 Sep 23;64(12):1254-6. doi: 10.1016/j.jacc.2014.06.1183. No abstract available.


Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor κB.

Walker AE, Kaplon RE, Pierce GL, Nowlan MJ, Seals DR.

Clin Sci (Lond). 2014 Dec;127(11):645-54. doi: 10.1042/CS20140030.


Epithelial sodium channel inhibition by amiloride on blood pressure and cardiovascular disease risk in young prehypertensives.

Bhagatwala J, Harris RA, Parikh SJ, Zhu H, Huang Y, Kotak I, Seigler N, Pierce GL, Egan BM, Dong Y.

J Clin Hypertens (Greenwich). 2014 Jan;16(1):47-53. doi: 10.1111/jch.12218. Epub 2013 Oct 31.


Localized increase of chemokines in the lumen of human cerebral aneurysms.

Chalouhi N, Points L, Pierce GL, Ballas Z, Jabbour P, Hasan D.

Stroke. 2013 Sep;44(9):2594-7. doi: 10.1161/STROKEAHA.113.002361. Epub 2013 Jul 25.


Oral BH4: a novel remedy for age-related skin microvascular impairment during heat stress or fool's elixir?

Pierce GL.

J Appl Physiol (1985). 2013 Oct 1;115(7):951-3. doi: 10.1152/japplphysiol.00785.2013. Epub 2013 Jul 11. No abstract available.


Aortic pulse wave velocity and reflecting distance estimation from peripheral waveforms in humans: detection of age- and exercise training-related differences.

Pierce GL, Casey DP, Fiedorowicz JG, Seals DR, Curry TB, Barnes JN, Wilson DR, Stauss HM.

Am J Physiol Heart Circ Physiol. 2013 Jul 1;305(1):H135-42. doi: 10.1152/ajpheart.00916.2012. Epub 2013 Apr 26.


Arterial stiffness and pulse-pressure amplification in overweight/obese African-American adolescents: relation with higher systolic and pulse pressure.

Pierce GL, Zhu H, Darracott K, Edet I, Bhagatwala J, Huang Y, Dong Y.

Am J Hypertens. 2013 Jan;26(1):20-6. doi: 10.1093/ajh/hps014.


The dependence of FMD% on baseline diameter: a problem solved by allometric scaling - no problem in this case.

DeVan AE, Pierce GL, Brooks FA, Seals DR.

Clin Sci (Lond). 2013 Mar 13;125(1):55-6. doi: 10.1042/CS20130047. No abstract available.


Targeting vascular endothelial cell insulin resistance in type 2 diabetes mellitus: is protein kinase cβ the bullseye for reducing vascular risk in diabetes?

Pierce GL.

Circulation. 2013 Jan 1;127(1):16-8. doi: 10.1161/CIRCULATIONAHA.112.150813. Epub 2012 Nov 30. No abstract available.


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