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Items: 15

1.

AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes.

Hui DJ, Edmonson SC, Podsakoff GM, Pien GC, Ivanciu L, Camire RM, Ertl H, Mingozzi F, High KA, Basner-Tschakarjan E.

Mol Ther Methods Clin Dev. 2015 Sep 30;2:15029. doi: 10.1038/mtm.2015.29. eCollection 2015.

2.

Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes.

Hui DJ, Basner-Tschakarjan E, Chen Y, Davidson RJ, Buchlis G, Yazicioglu M, Pien GC, Finn JD, Haurigot V, Tai A, Scott DW, Cousens LP, Zhou S, De Groot AS, Mingozzi F.

Mol Ther. 2013 Sep;21(9):1727-37. doi: 10.1038/mt.2013.166. Epub 2013 Jul 16.

3.

Coordination of multidisciplinary resources for vaccination of egg-allergic individuals during an H1N1 (novel) influenza pandemic.

Pien GC, LeBenger KS, Carotenuto DR, Difilippi M, Scolpino D, Simmons JM, Barrett C, Brenner RW.

Allergy Asthma Proc. 2010 Nov-Dec;31(6):507-10. doi: 10.2500/aap.2010.31.3396. Epub 2010 Oct 12.

PMID:
20943012
4.

Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction.

Finn JD, Hui D, Downey HD, Dunn D, Pien GC, Mingozzi F, Zhou S, High KA.

Mol Ther. 2010 Jan;18(1):135-42. doi: 10.1038/mt.2009.257. Epub 2009 Nov 10.

5.

Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors.

Pien GC, Basner-Tschakarjan E, Hui DJ, Mentlik AN, Finn JD, Hasbrouck NC, Zhou S, Murphy SL, Maus MV, Mingozzi F, Orange JS, High KA.

J Clin Invest. 2009 Jun;119(6):1688-95. doi: 10.1172/JCI36891. Epub 2009 May 11.

6.

Evaluation and clinical interpretation of hypergammaglobulinemia E: differentiating atopy from immunodeficiency.

Pien GC, Orange JS.

Ann Allergy Asthma Immunol. 2008 Apr;100(4):392-5. doi: 10.1016/S1081-1206(10)60605-9. Review.

PMID:
18450128
7.

The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system.

Huang D, Shi FD, Jung S, Pien GC, Wang J, Salazar-Mather TP, He TT, Weaver JT, Ljunggren HG, Biron CA, Littman DR, Ransohoff RM.

FASEB J. 2006 May;20(7):896-905.

PMID:
16675847
8.

A unique mechanism for innate cytokine promotion of T cell responses to viral infections.

Pien GC, Nguyen KB, Malmgaard L, Satoskar AR, Biron CA.

J Immunol. 2002 Nov 15;169(10):5827-37.

9.

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection.

Nguyen KB, Watford WT, Salomon R, Hofmann SR, Pien GC, Morinobu A, Gadina M, O'Shea JJ, Biron CA.

Science. 2002 Sep 20;297(5589):2063-6.

10.

Innate immune responses to LCMV infections: natural killer cells and cytokines.

Biron CA, Nguyen KB, Pien GC.

Curr Top Microbiol Immunol. 2002;263:7-27. Review.

PMID:
11987821
11.

SAP controls T cell responses to virus and terminal differentiation of TH2 cells.

Wu C, Nguyen KB, Pien GC, Wang N, Gullo C, Howie D, Sosa MR, Edwards MJ, Borrow P, Satoskar AR, Sharpe AH, Biron CA, Terhorst C.

Nat Immunol. 2001 May;2(5):410-4.

PMID:
11323694
12.

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox.

Nguyen KB, Cousens LP, Doughty LA, Pien GC, Durbin JE, Biron CA.

Nat Immunol. 2000 Jul;1(1):70-6.

PMID:
10881178
13.

Cutting edge: selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection.

Pien GC, Satoskar AR, Takeda K, Akira S, Biron CA.

J Immunol. 2000 Nov 1;165(9):4787-91.

14.
15.

Natural killer cells in antiviral defense: function and regulation by innate cytokines.

Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP.

Annu Rev Immunol. 1999;17:189-220. Review.

PMID:
10358757

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