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Items: 1 to 50 of 205

1.

Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes.

Maffi P, Lundgren T, Tufveson G, Rafael E, Shaw JAM, Liew A, Saudek F, Witkowski P, Golab K, Bertuzzi F, Gustafsson B, Daffonchio L, Ruffini PA, Piemonti L; and the REP0211 Study Group; REP0211 Study Group.

Diabetes Care. 2020 Feb 4. pii: dc191480. doi: 10.2337/dc19-1480. [Epub ahead of print]

PMID:
32019854
2.

Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children.

Vecchione A, Di Fonte R, Gerosa J, Jofra T, Cicalese MP, Napoleone V, Ippolito E, Galvani G, Ragogna F, Stabilini A, Bianconi E, Grogan P, Bonura C, Bonfanti R, Frontino G, Nano R, Melzi R, De Pellegrin M, Laurenzi A, Meschi F, Barera G, Rigamonti A, Indirli R, Bosi E, Piemonti L, Aiuti A, Battaglia M, Fousteri G.

Clin Immunol. 2020 Feb;211:108319. doi: 10.1016/j.clim.2019.108319. Epub 2019 Nov 30.

PMID:
31794865
3.

The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes.

Ramos-Rodríguez M, Raurell-Vila H, Colli ML, Alvelos MI, Subirana-Granés M, Juan-Mateu J, Norris R, Turatsinze JV, Nakayasu ES, Webb-Robertson BM, Inshaw JRJ, Marchetti P, Piemonti L, Esteller M, Todd JA, Metz TO, Eizirik DL, Pasquali L.

Nat Genet. 2019 Nov;51(11):1588-1595. doi: 10.1038/s41588-019-0524-6. Epub 2019 Nov 1.

PMID:
31676868
4.

Pharmacological Targeting of GLUT1 to Control Autoreactive T Cell Responses.

Di Dedda C, Vignali D, Piemonti L, Monti P.

Int J Mol Sci. 2019 Oct 8;20(19). pii: E4962. doi: 10.3390/ijms20194962. Review.

5.

Selective local irradiation improves islet engraftment and survival in intra-bone marrow islet transplantation.

Pellegrini S, Cantarelli E, Citro A, Incerti E, Piemonti L, Sordi V.

Cytotherapy. 2019 Oct;21(10):1025-1032. doi: 10.1016/j.jcyt.2019.07.005. Epub 2019 Aug 20.

PMID:
31444049
6.

Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study.

Nano R, Kerr-Conte JA, Scholz H, Engelse M, Karlsson M, Saudek F, Bosco D, Antonioli B, Bertuzzi F, Johnson PRV, Ludwing B, Ling Z, De Paep DL, Keymeulen B, Pattou F, Berney T, Korsgren O, de Koning E, Piemonti L.

Transplantation. 2020 Jan;104(1):190-196. doi: 10.1097/TP.0000000000002777.

PMID:
31365472
7.

Islets for Research: Nothing Is Perfect, but We Can Do Better.

Nano R, Kerr-Conte JA, Bosco D, Karlsson M, Lavallard V, Melzi R, Gmyr V, Mercalli A, Berney T, Pattou F, Korsgren O, Piemonti L.

Diabetes. 2019 Aug;68(8):1541-1543. doi: 10.2337/db19-0367.

8.

CCL2/MCP-1 and CXCL12/SDF-1 blockade by L-aptamers improve pancreatic islet engraftment and survival in mouse.

Citro A, Pellegrini S, Dugnani E, Eulberg D, Klussmann S, Piemonti L.

Am J Transplant. 2019 Nov;19(11):3131-3138. doi: 10.1111/ajt.15518. Epub 2019 Jul 18.

PMID:
31267721
9.

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.

Miguel-Escalada I, Bonàs-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G, Javierre BM, Rolando DMY, Farabella I, Morgan CC, García-Hurtado J, Beucher A, Morán I, Pasquali L, Ramos-Rodríguez M, Appel EVR, Linneberg A, Gjesing AP, Witte DR, Pedersen O, Grarup N, Ravassard P, Torrents D, Mercader JM, Piemonti L, Berney T, de Koning EJP, Kerr-Conte J, Pattou F, Fedko IO, Groop L, Prokopenko I, Hansen T, Marti-Renom MA, Fraser P, Ferrer J.

Nat Genet. 2019 Jul;51(7):1137-1148. doi: 10.1038/s41588-019-0457-0. Epub 2019 Jun 28.

10.

Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes.

Bolla AM, Caretto A, Laurenzi A, Scavini M, Piemonti L.

Nutrients. 2019 Apr 26;11(5). pii: E962. doi: 10.3390/nu11050962. Review.

11.

Glucose metabolism during tumorigenesis in the genetic mouse model of pancreatic cancer.

Pasquale V, Dugnani E, Liberati D, Marra P, Citro A, Canu T, Policardi M, Valla L, Esposito A, Piemonti L.

Acta Diabetol. 2019 Sep;56(9):1013-1022. doi: 10.1007/s00592-019-01335-4. Epub 2019 Apr 15.

PMID:
30989379
12.

Biofabrication of a vascularized islet organ for type 1 diabetes.

Citro A, Moser PT, Dugnani E, Rajab TK, Ren X, Evangelista-Leite D, Charest JM, Peloso A, Podesser BK, Manenti F, Pellegrini S, Piemonti L, Ott HC.

Biomaterials. 2019 Apr;199:40-51. doi: 10.1016/j.biomaterials.2019.01.035. Epub 2019 Jan 24.

PMID:
30735895
13.

Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice.

Giorgio C, Incerti M, Pala D, Russo S, Chiodelli P, Rusnati M, Cantoni AM, Di Lecce R, Barocelli E, Bertoni S, Ravassard P, Manenti F, Piemonti L, Ferlenghi F, Lodola A, Tognolini M.

Pharmacol Res. 2019 Mar;141:319-330. doi: 10.1016/j.phrs.2019.01.011. Epub 2019 Jan 6.

PMID:
30625359
14.

Diabetes-free survival after extended distal pancreatectomy and islet auto transplantation for benign or borderline/malignant lesions of the pancreas.

Balzano G, Maffi P, Nano R, Mercalli A, Melzi R, Aleotti F, De Cobelli F, Magistretti P, Scavini M, Secchi A, Falconi M, Piemonti L.

Am J Transplant. 2019 Mar;19(3):920-928. doi: 10.1111/ajt.15219. Epub 2019 Jan 23.

PMID:
30549450
15.

Measurement of Autoantibodies to Gastric H+,K+-ATPase (ATP4A/B) Using a Luciferase Immunoprecipitation System (LIPS).

Lahner E, Marzinotto I, Brigatti C, Davidson H, Wenzlau J, Piemonti L, Annibale B, Lampasona V.

Methods Mol Biol. 2019;1901:113-131. doi: 10.1007/978-1-4939-8949-2_10.

PMID:
30539573
16.

Undiagnosed prediabetes is highly prevalent in primary infertile men - results from a cross-sectional study.

Boeri L, Capogrosso P, Ventimiglia E, Pederzoli F, Frego N, Cazzaniga W, Chierigo F, Alfano M, Piemonti L, Viganò P, Pontillo M, Montanari E, Montorsi F, Salonia A.

BJU Int. 2019 Jun;123(6):1070-1077. doi: 10.1111/bju.14558. Epub 2018 Oct 16.

17.

Gene expression analysis of embryonic pancreas development master regulators and terminal cell fate markers in resected pancreatic cancer: A correlation with clinical outcome.

Dugnani E, Sordi V, Pellegrini S, Chimienti R, Marzinotto I, Pasquale V, Liberati D, Balzano G, Doglioni C, Reni M, Gandolfi A, Falconi M, Lampasona V, Piemonti L.

Pancreatology. 2018 Dec;18(8):945-953. doi: 10.1016/j.pan.2018.09.006. Epub 2018 Sep 25.

PMID:
30293872
18.

Differentiation of Sendai Virus-Reprogrammed iPSC into β Cells, Compared with Human Pancreatic Islets and Immortalized β Cell Line.

Pellegrini S, Manenti F, Chimienti R, Nano R, Ottoboni L, Ruffini F, Martino G, Ravassard P, Piemonti L, Sordi V.

Cell Transplant. 2018 Oct;27(10):1548-1560. doi: 10.1177/0963689718798564. Epub 2018 Sep 25.

19.

Regenerative Medicine and Diabetes: Targeting the Extracellular Matrix Beyond the Stem Cell Approach and Encapsulation Technology.

Peloso A, Citro A, Zoro T, Cobianchi L, Kahler-Quesada A, Bianchi CM, Andres A, Berishvili E, Piemonti L, Berney T, Toso C, Oldani G.

Front Endocrinol (Lausanne). 2018 Aug 31;9:445. doi: 10.3389/fendo.2018.00445. eCollection 2018. Review.

20.

Study of 2009 H1N1 Pandemic Influenza Virus as a Possible Causative Agent of Diabetes.

Capua I, Mercalli A, Romero-Tejeda A, Pizzuto MS, Kasloff S, Sordi V, Marzinotto I, Lampasona V, Vicenzi E, De Battisti C, Bonfanti R, Rigamonti A, Terregino C, Doglioni C, Cattoli G, Piemonti L.

J Clin Endocrinol Metab. 2018 Dec 1;103(12):4343-4356. doi: 10.1210/jc.2018-00862.

PMID:
30203067
21.

Islet Allotransplantation in the Bone Marrow of Patients With Type 1 Diabetes: A Pilot Randomized Trial.

Maffi P, Nano R, Monti P, Melzi R, Sordi V, Mercalli A, Pellegrini S, Ponzoni M, Peccatori J, Messina C, Nocco A, Cardillo M, Scavini M, Magistretti P, Doglioni C, Ciceri F, Bloem SJ, Roep BO, Secchi A, Piemonti L.

Transplantation. 2019 Apr;103(4):839-851. doi: 10.1097/TP.0000000000002416.

PMID:
30130323
22.

Pluripotent stem cell replacement approaches to treat type 1 diabetes.

Pellegrini S, Piemonti L, Sordi V.

Curr Opin Pharmacol. 2018 Dec;43:20-26. doi: 10.1016/j.coph.2018.07.007. Epub 2018 Jul 30. Review.

PMID:
30071348
23.

Four-class tumor staging for early diagnosis and monitoring of murine pancreatic cancer using magnetic resonance and ultrasound.

Dugnani E, Pasquale V, Marra P, Liberati D, Canu T, Perani L, De Sanctis F, Ugel S, Invernizzi F, Citro A, Venturini M, Doglioni C, Esposito A, Piemonti L.

Carcinogenesis. 2018 Sep 21;39(9):1197-1206. doi: 10.1093/carcin/bgy094.

PMID:
30052815
24.

The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans.

Izzi-Engbeaya C, Comninos AN, Clarke SA, Jomard A, Yang L, Jones S, Abbara A, Narayanaswamy S, Eng PC, Papadopoulou D, Prague JK, Bech P, Godsland IF, Bassett P, Sands C, Camuzeaux S, Gomez-Romero M, Pearce JTM, Lewis MR, Holmes E, Nicholson JK, Tan T, Ratnasabapathy R, Hu M, Carrat G, Piemonti L, Bugliani M, Marchetti P, Johnson PR, Hughes SJ, James Shapiro AM, Rutter GA, Dhillo WS.

Diabetes Obes Metab. 2018 Dec;20(12):2800-2810. doi: 10.1111/dom.13460. Epub 2018 Aug 16.

25.

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.

Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D'Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A.

Transplantation. 2018 Aug;102(8):1223-1229. doi: 10.1097/TP.0000000000002217. Review.

26.

Allo- and auto-percutaneous intra-portal pancreatic islet transplantation (PIPIT) for diabetes cure and prevention: the role of imaging and interventional radiology.

Venturini M, Sallemi C, Marra P, Palmisano A, Agostini G, Lanza C, Balzano G, Falconi M, Secchi A, Fiorina P, Piemonti L, Maffi P, Esposito A, De Cobelli F, Del Maschio A.

Gland Surg. 2018 Apr;7(2):117-131. doi: 10.21037/gs.2017.11.12. Review.

27.

Targeting GLP-1 receptor trafficking to improve agonist efficacy.

Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Corrêa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR.

Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2.

28.

No evidence of pancreatic ductal adenocarcinoma specific autoantibodies to Ezrin in a liquid phase LIPS immunoassay.

Liberati D, Marzinotto I, Brigatti C, Dugnani E, Pasquale V, Reni M, Balzano G, Falconi M, Piemonti L, Lampasona V.

Cancer Biomark. 2018;22(2):351-357. doi: 10.3233/CBM-181218.

PMID:
29660901
29.

Insulin-mimetic effects of short-term rapamycin in type 1 diabetic patients prior to islet transplantation.

Benedini S, Ermetici F, Briganti S, Codella R, Terruzzi I, Maffi P, Caldara R, Secchi A, Nano R, Piemonti L, Alejandro R, Ricordi C, Luzi L.

Acta Diabetol. 2018 Jul;55(7):715-722. doi: 10.1007/s00592-018-1141-z. Epub 2018 Apr 13.

PMID:
29654388
30.

The role of neutrophil-to-lymphocyte ratio in men with erectile dysfunction-preliminary findings of a real-life cross-sectional study.

Ventimiglia E, Cazzaniga W, Pederzoli F, Frego N, Chierigo F, Capogrosso P, Boeri L, Dehò F, Abbate C, Moretti D, Piemonti L, Montorsi F, Salonia A.

Andrology. 2018 Jul;6(4):559-563. doi: 10.1111/andr.12489. Epub 2018 Apr 2.

31.

The first 142 amino acids of glutamate decarboxylase do not contribute to epitopes recognized by autoantibodies associated with Type 1 diabetes.

Wyatt RC, Brigatti C, Liberati D, Grace SL, Gillard BT, Long AE, Marzinotto I, Shoemark DK, Chandler KA, Achenbach P, Gillespie KM, Piemonti L, Lampasona V, Williams AJK.

Diabet Med. 2018 Jul;35(7):954-963. doi: 10.1111/dme.13628. Epub 2018 Apr 19.

PMID:
29577424
32.

The potential and challenges of alternative sources of β cells for the cure of type 1 diabetes.

Cito M, Pellegrini S, Piemonti L, Sordi V.

Endocr Connect. 2018 Mar;7(3):R114-R125. doi: 10.1530/EC-18-0012. Review.

33.

Defining Outcomes for β-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transplantation. 2018 Sep;102(9):1479-1486. doi: 10.1097/TP.0000000000002158. Review.

34.

Defining outcomes for beta cell replacement therapy: a work in progress.

Piemonti L, de Koning EJP, Berney T, Odorico JS, Markmann JF, Stock PG, Rickels MR.

Diabetologia. 2018 Jun;61(6):1273-1276. doi: 10.1007/s00125-018-4588-0. Epub 2018 Mar 6.

35.

Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes.

Vignali D, Cantarelli E, Bordignon C, Canu A, Citro A, Annoni A, Piemonti L, Monti P.

Diabetes. 2018 May;67(5):936-945. doi: 10.2337/db17-1390. Epub 2018 Mar 5.

36.

Defining outcomes for β-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transpl Int. 2018 Apr;31(4):343-352. doi: 10.1111/tri.13138. Review.

37.

Proceedings of the signature series event of the international society for cellular therapy: "Advancements in cellular therapies and regenerative medicine in digestive diseases," London, United Kingdom, May 3, 2017.

Ciccocioppo R, Dos Santos CC, Baumgart DC, Cangemi GC, Cardinale V, Ciacci C, De Coppi P, Haldar D, Klersy C, Nostro MC, Ott M, Piemonti L, Tomei AA, Uygun B, Vetrano S, Orlando G.

Cytotherapy. 2018 Mar;20(3):461-476. doi: 10.1016/j.jcyt.2017.12.004. Epub 2018 Feb 15.

38.

A novel LIPS assay for insulin autoantibodies.

Liberati D, Wyatt RC, Brigatti C, Marzinotto I, Ferrari M, Bazzigaluppi E, Bosi E, Gillard BT, Gillespie KM, Gorus F, Weets I, Balti E, Piemonti L, Achenbach P, Williams AJK, Lampasona V.

Acta Diabetol. 2018 Mar;55(3):263-270. doi: 10.1007/s00592-017-1082-y. Epub 2018 Jan 5.

PMID:
29305766
39.

A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells.

Buenaventura T, Kanda N, Douzenis PC, Jones B, Bloom SR, Chabosseau P, Corrêa IR Jr, Bosco D, Piemonti L, Marchetti P, Johnson PR, Shapiro AMJ, Rutter GA, Tomas A.

Diabetes. 2018 Mar;67(3):385-399. doi: 10.2337/db17-0639. Epub 2017 Dec 28.

40.

MiR-184 expression is regulated by AMPK in pancreatic islets.

Martinez-Sanchez A, Nguyen-Tu MS, Cebola I, Yavari A, Marchetti P, Piemonti L, de Koning E, Shapiro AMJ, Johnson P, Sakamoto K, Smith DM, Leclerc I, Ashrafian H, Ferrer J, Rutter GA.

FASEB J. 2018 May;32(5):2587-2600. doi: 10.1096/fj.201701100R. Epub 2018 Jan 8.

41.

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.

Fine NHF, Doig CL, Elhassan YS, Vierra NC, Marchetti P, Bugliani M, Nano R, Piemonti L, Rutter GA, Jacobson DA, Lavery GG, Hodson DJ.

Diabetes. 2018 Feb;67(2):278-290. doi: 10.2337/db16-1356. Epub 2017 Dec 4.

42.

miR-204 is associated with an endocrine phenotype in human pancreatic islets but does not regulate the insulin mRNA through MAFA.

Marzinotto I, Pellegrini S, Brigatti C, Nano R, Melzi R, Mercalli A, Liberati D, Sordi V, Ferrari M, Falconi M, Doglioni C, Ravassard P, Piemonti L, Lampasona V.

Sci Rep. 2017 Oct 25;7(1):14051. doi: 10.1038/s41598-017-13622-7.

43.

Integrating T cell metabolism in cancer immunotherapy.

Dugnani E, Pasquale V, Bordignon C, Canu A, Piemonti L, Monti P.

Cancer Lett. 2017 Dec 28;411:12-18. doi: 10.1016/j.canlet.2017.09.039. Epub 2017 Sep 30. Review.

PMID:
28974448
44.

Anti-Inflammatory Strategies in Intrahepatic Islet Transplantation: A Comparative Study in Preclinical Models.

Citro A, Cantarelli E, Pellegrini S, Dugnani E, Piemonti L.

Transplantation. 2018 Feb;102(2):240-248. doi: 10.1097/TP.0000000000001925.

PMID:
28902069
45.

A preoperative score to predict early death after pancreatic cancer resection.

Balzano G, Dugnani E, Crippa S, Scavini M, Pasquale V, Aleotti F, Liberati D, Gandolfi A, Belfiori G, Reni M, Doglioni C, Ruffo G, Marmorale C, Falconi M, Piemonti L.

Dig Liver Dis. 2017 Sep;49(9):1050-1056. doi: 10.1016/j.dld.2017.06.012. Epub 2017 Jul 1.

PMID:
28734776
46.

Immunological Issues After Stem Cell-Based β Cell Replacement.

Sordi V, Pellegrini S, Piemonti L.

Curr Diab Rep. 2017 Sep;17(9):68. doi: 10.1007/s11892-017-0901-4. Review.

PMID:
28726153
47.

Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific.

Marzinotto I, Liberati D, Brigatti C, Bonfanti R, Stabilini A, Monti P, Bosi E, Piemonti L, Lampasona V.

Diabetologia. 2017 Sep;60(9):1834-1835. doi: 10.1007/s00125-017-4376-2. Epub 2017 Jul 19. No abstract available.

PMID:
28725911
48.

Stem cells to restore insulin production and cure diabetes.

Sordi V, Pellegrini S, Krampera M, Marchetti P, Pessina A, Ciardelli G, Fadini G, Pintus C, Pantè G, Piemonti L.

Nutr Metab Cardiovasc Dis. 2017 Jul;27(7):583-600. doi: 10.1016/j.numecd.2017.02.004. Epub 2017 Feb 21. Review.

PMID:
28545927
49.

Modeling the Iatrogenic Pancreatic Cancer Risk After Islet Autotransplantation in Mouse.

Dugnani E, Pasquale V, Liberati D, Citro A, Cantarelli E, Pellegrini S, Marra P, Canu T, Balzano G, Scavini M, Esposito A, Doglioni C, Piemonti L.

Am J Transplant. 2017 Oct;17(10):2720-2727. doi: 10.1111/ajt.14360. Epub 2017 Jun 12.

50.

Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.

Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S.

Sci Rep. 2017 May 9;7:46801. doi: 10.1038/srep46801. No abstract available.

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