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Items: 1 to 50 of 113

1.

APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health.

Wong MWK, Braidy N, Crawford J, Pickford R, Song F, Mather KA, Attia J, Brodaty H, Sachdev P, Poljak A.

J Alzheimers Dis. 2019 Oct 17. doi: 10.3233/JAD-190524. [Epub ahead of print]

PMID:
31640095
2.

The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.

Stayte S, Laloli KJ, Rentsch P, Lowth A, Li KM, Pickford R, Vissel B.

Exp Neurol. 2019 Sep 9;323:113062. doi: 10.1016/j.expneurol.2019.113062. [Epub ahead of print]

PMID:
31513786
3.

Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma.

Wong MWK, Braidy N, Pickford R, Sachdev PS, Poljak A.

Front Neurol. 2019 Aug 21;10:879. doi: 10.3389/fneur.2019.00879. eCollection 2019.

4.

[Breathing: Ambient Air Pollution and Health - Part III].

Schulz H, Karrasch S, Bölke G, Cyrys J, Hornberg C, Pickford R, Schneider A, Witt C, Hoffmann B.

Pneumologie. 2019 Jul;73(7):407-429. doi: 10.1055/a-0920-6423. Epub 2019 Jul 10. German.

5.

[Breathing: Ambient Air Pollution and Health - Part II].

Schulz H, Karrasch S, Bölke G, Cyrys J, Hornberg C, Pickford R, Schneider A, Witt C, Hoffmann B.

Pneumologie. 2019 Jun;73(6):347-373. doi: 10.1055/a-0895-6494. Epub 2019 Jun 11. Review. German.

6.

Plastic leachates impair growth and oxygen production in Prochlorococcus, the ocean's most abundant photosynthetic bacteria.

Tetu SG, Sarker I, Schrameyer V, Pickford R, Elbourne LDH, Moore LR, Paulsen IT.

Commun Biol. 2019 May 14;2:184. doi: 10.1038/s42003-019-0410-x. eCollection 2019.

7.

[Breathing: Ambient Air Pollution and Health - Part I].

Schulz H, Karrasch S, Bölke G, Cyrys J, Hornberg C, Pickford R, Schneider A, Witt C, Hoffmann B.

Pneumologie. 2019 May;73(5):288-305. doi: 10.1055/a-0882-9366. Epub 2019 Apr 16. German.

8.

Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI.

Wong MWK, Braidy N, Pickford R, Vafaee F, Crawford J, Muenchhoff J, Schofield P, Attia J, Brodaty H, Sachdev P, Poljak A.

PLoS One. 2019 Mar 20;14(3):e0214141. doi: 10.1371/journal.pone.0214141. eCollection 2019.

9.

Bioinformatic, phylogenetic and chemical analysis of the UV-absorbing compounds scytonemin and mycosporine-like amino acids from the microbial mat communities of Shark Bay, Australia.

D'Agostino PM, Woodhouse JN, Liew HT, Sehnal L, Pickford R, Wong HL, Burns BP, Neilan BA.

Environ Microbiol. 2019 Feb;21(2):702-715. doi: 10.1111/1462-2920.14517. Epub 2019 Jan 25.

PMID:
30589201
10.

Quantifying Inorganic Nitrogen Assimilation by Synechococcus Using Bulk and Single-Cell Mass Spectrometry: A Comparative Study.

Giardina M, Cheong S, Marjo CE, Clode PL, Guagliardo P, Pickford R, Pernice M, Seymour JR, Raina JB.

Front Microbiol. 2018 Nov 27;9:2847. doi: 10.3389/fmicb.2018.02847. eCollection 2018.

11.

Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness.

Aw WC, Towarnicki SG, Melvin RG, Youngson NA, Garvin MR, Hu Y, Nielsen S, Thomas T, Pickford R, Bustamante S, Vila-Sanjurjo A, Smyth GK, Ballard JWO.

PLoS Genet. 2018 Nov 6;14(11):e1007735. doi: 10.1371/journal.pgen.1007735. eCollection 2018 Nov. Review.

12.

Reduced glucocerebrosidase activity in monocytes from patients with Parkinson's disease.

Atashrazm F, Hammond D, Perera G, Dobson-Stone C, Mueller N, Pickford R, Kim WS, Kwok JB, Lewis SJG, Halliday GM, Dzamko N.

Sci Rep. 2018 Oct 18;8(1):15446. doi: 10.1038/s41598-018-33921-x.

13.

Insertions within the Saxitoxin Biosynthetic Gene Cluster Result in Differential Toxin Profiles.

Cullen A, D'Agostino PM, Mazmouz R, Pickford R, Wood S, Neilan BA.

ACS Chem Biol. 2018 Nov 16;13(11):3107-3114. doi: 10.1021/acschembio.8b00608. Epub 2018 Oct 19.

PMID:
30296060
14.

Lipidomics Analysis of Behavioral Variant Frontotemporal Dementia: A Scope for Biomarker Development.

Kim WS, Jary E, Pickford R, He Y, Ahmed RM, Piguet O, Hodges JR, Halliday GM.

Front Neurol. 2018 Feb 28;9:104. doi: 10.3389/fneur.2018.00104. eCollection 2018.

15.

AZA-MS: a novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo.

Unnikrishnan A, Vo ANQ, Pickford R, Raftery MJ, Nunez AC, Verma A, Hesson LB, Pimanda JE.

Leukemia. 2018 Apr;32(4):900-910. doi: 10.1038/leu.2017.340. Epub 2017 Nov 29.

16.

Naturally occurring folates in selected traditionally prepared foods in Southern India.

Vishnumohan S, Pickford R, Arcot J.

J Food Sci Technol. 2017 Dec;54(13):4173-4180. doi: 10.1007/s13197-017-2870-7. Epub 2017 Oct 10.

17.

Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy.

von Jonquieres G, Spencer ZHT, Rowlands BD, Klugmann CB, Bongers A, Harasta AE, Parley KE, Cederholm J, Teahan O, Pickford R, Delerue F, Ittner LM, Fröhlich D, McLean CA, Don AS, Schneider M, Housley GD, Rae CD, Klugmann M.

Acta Neuropathol. 2018 Jan;135(1):95-113. doi: 10.1007/s00401-017-1784-9. Epub 2017 Nov 7.

18.

AGE-albumin enhances ABCA1 degradation by ubiquitin-proteasome and lysosomal pathways in macrophages.

Iborra RT, Machado-Lima A, Okuda LS, Pinto PR, Nakandakare ER, Machado UF, Correa-Giannella ML, Pickford R, Woods T, Brimble MA, Rye KA, Lu R, Yokoyama S, Passarelli M.

J Diabetes Complications. 2018 Jan;32(1):1-10. doi: 10.1016/j.jdiacomp.2017.09.012. Epub 2017 Sep 23.

PMID:
29097054
19.

N-acetylcysteine Counteracts Adipose Tissue Macrophage Infiltration and Insulin Resistance Elicited by Advanced Glycated Albumin in Healthy Rats.

da Silva KS, Pinto PR, Fabre NT, Gomes DJ, Thieme K, Okuda LS, Iborra RT, Freitas VG, Shimizu MHM, Teodoro WR, Marie SKN, Woods T, Brimble MA, Pickford R, Rye KA, Okamoto M, Catanozi S, Correa-Giannela ML, Machado UF, Passarelli M.

Front Physiol. 2017 Sep 22;8:723. doi: 10.3389/fphys.2017.00723. eCollection 2017.

20.

Molecular and morphological survey of saxitoxin-producing cyanobacterium Dolichospermum circinale (Anabaena circinalis) isolated from geographically distinct regions of Australia.

Pereyra JPA, D'Agostino PM, Mazmouz R, Woodhouse JN, Pickford R, Jameson I, Neilan BA.

Toxicon. 2017 Nov;138:68-77. doi: 10.1016/j.toxicon.2017.08.006. Epub 2017 Aug 7.

PMID:
28797629
21.

Directing the Heterologous Production of Specific Cyanobacterial Toxin Variants.

Liu T, Mazmouz R, Ongley SE, Chau R, Pickford R, Woodhouse JN, Neilan BA.

ACS Chem Biol. 2017 Aug 18;12(8):2021-2029. doi: 10.1021/acschembio.7b00181. Epub 2017 Jun 7.

PMID:
28570054
22.

Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers.

Wong MW, Braidy N, Poljak A, Pickford R, Thambisetty M, Sachdev PS.

Alzheimers Dement. 2017 Jul;13(7):810-827. doi: 10.1016/j.jalz.2017.01.008. Epub 2017 Feb 24. Review.

PMID:
28242299
23.

Is there a role for stool metabolomics in cystic fibrosis?

Kaakoush NO, Pickford R, Jaffe A, Ooi CY.

Pediatr Int. 2016 Aug;58(8):808-11. doi: 10.1111/ped.13063. Review.

PMID:
27553892
24.

Heterologous Production of Cyanobacterial Mycosporine-Like Amino Acids Mycosporine-Ornithine and Mycosporine-Lysine in Escherichia coli.

Katoch M, Mazmouz R, Chau R, Pearson LA, Pickford R, Neilan BA.

Appl Environ Microbiol. 2016 Sep 30;82(20):6167-6173. Print 2016 Oct 15.

25.

Comparative Profiling and Discovery of Novel Glycosylated Mycosporine-Like Amino Acids in Two Strains of the Cyanobacterium Scytonema cf. crispum.

D'Agostino PM, Javalkote VS, Mazmouz R, Pickford R, Puranik PR, Neilan BA.

Appl Environ Microbiol. 2016 Sep 16;82(19):5951-9. doi: 10.1128/AEM.01633-16. Print 2016 Oct 1.

26.

Glycated albumin induces lipid infiltration in mice aorta independently of DM and RAS local modulation by inducing lipid peroxidation and inflammation.

Gomes DJ, Velosa AP, Okuda LS, Fusco FB, da Silva KS, Pinto PR, Nakandakare ER, Correa-Giannella ML, Woods T, Brimble MA, Pickford R, Rye KA, Teodoro WR, Catanozi S, Passarelli M.

J Diabetes Complications. 2016 Nov - Dec;30(8):1614-1621. doi: 10.1016/j.jdiacomp.2016.07.001. Epub 2016 Jul 5.

PMID:
27440461
27.

Aptamer based peptide enrichment for quantitative analysis of gonadotropin-releasing hormone by LC-MS/MS.

Richards SL, Cawley AT, Cavicchioli R, Suann CJ, Pickford R, Raftery MJ.

Talanta. 2016 Apr 1;150:671-80. doi: 10.1016/j.talanta.2016.01.006. Epub 2016 Jan 7.

PMID:
26838458
28.

Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain.

Kashem MA, Ahmed S, Sultana N, Ahmed EU, Pickford R, Rae C, Šerý O, McGregor IS, Balcar VJ.

Neurochem Res. 2016 Feb;41(1-2):385-97. doi: 10.1007/s11064-016-1830-3. Epub 2016 Jan 22.

PMID:
26801172
29.

Large Scale Mass Spectrometry-based Identifications of Enzyme-mediated Protein Methylation Are Subject to High False Discovery Rates.

Hart-Smith G, Yagoub D, Tay AP, Pickford R, Wilkins MR.

Mol Cell Proteomics. 2016 Mar;15(3):989-1006. doi: 10.1074/mcp.M115.055384. Epub 2015 Dec 23.

30.

Assaying Ceramide Synthase Activity In Vitro and in Living Cells Using Liquid Chromatography-Mass Spectrometry.

Lim XY, Pickford R, Don AS.

Methods Mol Biol. 2016;1376:11-22. doi: 10.1007/978-1-4939-3170-5_2.

PMID:
26552671
31.

Thioimidazoline based compounds reverse glucocorticoid resistance in human acute lymphoblastic leukemia xenografts.

Toscan CE, Rahimi M, Bhadbhade M, Pickford R, McAlpine SR, Lock RB.

Org Biomol Chem. 2015 Jun 14;13(22):6299-312. doi: 10.1039/c5ob00779h.

PMID:
25967739
32.

Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases.

Yau YY, Leong RW, Shin S, Bustamante S, Pickford R, Hejazi L, Campbell B, Wasinger VC.

Discov Med. 2014 Sep;18(98):113-24.

33.

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis.

Couttas TA, Kain N, Daniels B, Lim XY, Shepherd C, Kril J, Pickford R, Li H, Garner B, Don AS.

Acta Neuropathol Commun. 2014 Jan 23;2:9. doi: 10.1186/2051-5960-2-9.

34.

Quantitative analysis of tissue folate using ultra high-performance liquid chromatography tandem mass spectrometry.

Liu J, Pickford R, Meagher AP, Ward RL.

Anal Biochem. 2011 Apr 15;411(2):210-7. doi: 10.1016/j.ab.2010.12.033. Epub 2010 Dec 28.

PMID:
21192913
35.

The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon.

Mladenova D, Daniel JJ, Dahlstrom JE, Bean E, Gupta R, Pickford R, Currey N, Musgrove EA, Kohonen-Corish MR.

Gut. 2011 Mar;60(3):350-60. doi: 10.1136/gut.2010.208314. Epub 2010 Oct 27.

PMID:
20980345
36.

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity.

Hoehn KL, Turner N, Swarbrick MM, Wilks D, Preston E, Phua Y, Joshi H, Furler SM, Larance M, Hegarty BD, Leslie SJ, Pickford R, Hoy AJ, Kraegen EW, James DE, Cooney GJ.

Cell Metab. 2010 Jan;11(1):70-6. doi: 10.1016/j.cmet.2009.11.008.

37.

Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteria.

Kellmann R, Mihali TK, Jeon YJ, Pickford R, Pomati F, Neilan BA.

Appl Environ Microbiol. 2008 Jul;74(13):4044-53. doi: 10.1128/AEM.00353-08. Epub 2008 May 16.

38.

Mass spectrometry of carbohydrates: newer aspects.

Rodrigues JA, Taylor AM, Sumpton DP, Reynolds JC, Pickford R, Thomas-Oates J.

Adv Carbohydr Chem Biochem. 2007;61:59-141. No abstract available.

PMID:
17931550
39.

Investigation of the lipid component of neuromelanin.

Fedorow H, Pickford R, Kettle E, Cartwright M, Halliday GM, Gerlach M, Riederer P, Garner B, Double KL.

J Neural Transm (Vienna). 2006 Jun;113(6):735-9. Epub 2006 May 26.

PMID:
16755377
40.

Dolichol is the major lipid component of human substantia nigra neuromelanin.

Fedorow H, Pickford R, Hook JM, Double KL, Halliday GM, Gerlach M, Riederer P, Garner B.

J Neurochem. 2005 Feb;92(4):990-5.

41.

A statistical comparison of silver and SYPRO Ruby staining for proteomic analysis.

White IR, Pickford R, Wood J, Skehel JM, Gangadharan B, Cutler P.

Electrophoresis. 2004 Sep;25(17):3048-54.

PMID:
15349947
42.

2-Dimethylarsinothioyl acetic acid identified in a biological sample: the first occurrence of a mammalian arsinothioyl metabolite.

Hansen HR, Pickford R, Thomas-Oates J, Jaspars M, Feldmann J.

Angew Chem Int Ed Engl. 2004 Jan 3;43(3):337-40. No abstract available.

PMID:
14705091
43.

Characterization of two Pseudomonas putida lipopeptide biosurfactants, putisolvin I and II, which inhibit biofilm formation and break down existing biofilms.

Kuiper I, Lagendijk EL, Pickford R, Derrick JP, Lamers GE, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV.

Mol Microbiol. 2004 Jan;51(1):97-113.

44.

Arsenosugar identification in seaweed extracts using high-performance liquid chromatography/electrospray ion trap mass spectrometry.

Miguens-Rodriguez M, Pickford R, Thomas-Oates JE, Pergantis SA.

Rapid Commun Mass Spectrom. 2002;16(5):323-31.

PMID:
11857714
45.

An integrated proteomic approach to studying glomerular nephrotoxicity.

Cutler P, Bell DJ, Birrell HC, Connelly JC, Connor SC, Holmes E, Mitchell BC, Monté SY, Neville BA, Pickford R, Polley S, Schneider K, Skehel JM.

Electrophoresis. 1999 Dec;20(18):3647-58.

PMID:
10612292
46.

Conservative management of splenic trauma.

Daoud RA, Taghizadeh AK, Pickford RB, Jones DR.

J R Army Med Corps. 1999 Jun;145(2):69-72.

PMID:
10420341
47.

Volumetric assessment of carotid artery bifurcation using freehand-acquired, compound 3D ultrasound.

Allott CP, Barry CD, Pickford R, Waterton JC.

Br J Radiol. 1999 Mar;72(855):289-92.

PMID:
10396220
48.

Metabolism of Casodex in laboratory animals.

Boyle GW, McKillop D, Phillips PJ, Harding JR, Pickford R, McCormick AD.

Xenobiotica. 1993 Jul;23(7):781-98.

PMID:
8237060
49.

1H-NMR spectroscopy as a means of monitoring nephrotoxicity as exemplified by studies with cephaloridine.

Murgatroyd LB, Pickford RJ, Smith IK, Wilson ID, Middleton BJ.

Hum Exp Toxicol. 1992 Jan;11(1):35-41.

PMID:
1354458
50.

beta-Hydroxybutyrate: a urinary marker of imipenem induced nephrotoxicity in the cynomolgus monkey detected by high field 1H NMR spectroscopy.

Harrison MP, Jones DV, Pickford RJ, Wilson ID.

Biochem Pharmacol. 1991 Jun 15;41(12):2045-9.

PMID:
2039554

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