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Items: 44

1.

DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts.

Richards LA, Kumari A, Knezevic K, Thoms JA, von Jonquieres G, Napier CE, Ali Z, O'Brien R, Marks-Bluth J, Maritz MF, Pickett HA, Morris J, Pimanda JE, MacKenzie KL.

Haematologica. 2019 Aug 14. pii: haematol.2018.215699. doi: 10.3324/haematol.2018.215699. [Epub ahead of print]

2.

Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells.

Le TYL, Pickett HA, Yang A, Ho JWK, Thavapalachandran S, Igoor S, Yang SF, Farraha M, Voges HK, Hudson JE, Dos Remedios CG, Bryan TM, Kizana E, Chong JJH.

Sci Rep. 2019 Jul 22;9(1):10579. doi: 10.1038/s41598-019-47022-w.

3.

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT).

Lu R, O'Rourke JJ, Sobinoff AP, Allen JAM, Nelson CB, Tomlinson CG, Lee M, Reddel RR, Deans AJ, Pickett HA.

Nat Commun. 2019 May 28;10(1):2252. doi: 10.1038/s41467-019-10180-6.

4.

Structural and functional characterization of the RBBP4-ZNF827 interaction and its role in NuRD recruitment to telomeres.

Yang SF, Sun AA, Shi Y, Li F, Pickett HA.

Biochem J. 2018 Aug 31;475(16):2667-2679. doi: 10.1042/BCJ20180310.

PMID:
30045876
5.

Telomere Loop Dynamics in Chromosome End Protection.

Van Ly D, Low RRJ, Frölich S, Bartolec TK, Kafer GR, Pickett HA, Gaus K, Cesare AJ.

Mol Cell. 2018 Aug 16;71(4):510-525.e6. doi: 10.1016/j.molcel.2018.06.025. Epub 2018 Jul 19.

6.

Telomere sequence content can be used to determine ALT activity in tumours.

Lee M, Teber ET, Holmes O, Nones K, Patch AM, Dagg RA, Lau LMS, Lee JH, Napier CE, Arthur JW, Grimmond SM, Hayward NK, Johansson PA, Mann GJ, Scolyer RA, Wilmott JS, Reddel RR, Pearson JV, Waddell N, Pickett HA.

Nucleic Acids Res. 2018 Jun 1;46(10):4903-4918. doi: 10.1093/nar/gky297.

7.

Platelet-Derived Growth Factor Receptor-Alpha Expressing Cardiac Progenitor Cells Can Be Derived from Previously Cryopreserved Human Heart Samples.

Le TYL, Pickett HA, Dos Remedios CG, Barbaro PM, Kizana E, Chong JJH.

Stem Cells Dev. 2018 Feb 1;27(3):184-198. doi: 10.1089/scd.2017.0082. Epub 2018 Jan 16.

PMID:
29205098
8.

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity.

Chan FL, Vinod B, Novy K, Schittenhelm RB, Huang C, Udugama M, Nunez-Iglesias J, Lin JI, Hii L, Chan J, Pickett HA, Daly RJ, Wong LH.

Nucleic Acids Res. 2017 Dec 1;45(21):12340-12353. doi: 10.1093/nar/gkx904.

9.

Functional dissection of breast cancer risk-associated TERT promoter variants.

Helbig S, Wockner L, Bouendeu A, Hille-Betz U, McCue K, French JD, Edwards SL, Pickett HA, Reddel RR, Chenevix-Trench G, Dörk T, Beesley J.

Oncotarget. 2017 May 26;8(40):67203-67217. doi: 10.18632/oncotarget.18226. eCollection 2017 Sep 15.

10.

Alternative Lengthening of Telomeres: DNA Repair Pathways Converge.

Sobinoff AP, Pickett HA.

Trends Genet. 2017 Dec;33(12):921-932. doi: 10.1016/j.tig.2017.09.003. Epub 2017 Sep 29. Review.

PMID:
28969871
11.

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours.

Scarpa A, Chang DK, Nones K, Corbo V, Patch AM, Bailey P, Lawlor RT, Johns AL, Miller DK, Mafficini A, Rusev B, Scardoni M, Antonello D, Barbi S, Sikora KO, Cingarlini S, Vicentini C, McKay S, Quinn MCJ, Bruxner TJC, Christ AN, Harliwong I, Idrisoglu S, McLean S, Nourse C, Nourbakhsh E, Wilson PJ, Anderson MJ, Fink JL, Newell F, Waddell N, Holmes O, Kazakoff SH, Leonard C, Wood S, Xu Q, Hiriyur Nagaraj S, Amato E, Dalai I, Bersani S, Cataldo I, Dei Tos AP, Capelli P, Vittoria Davì M, Landoni L, Malpaga A, Miotto M, Whitehall VLJ, Leggett BA, Harris JL, Harris J, Jones MD, Humphris J, Chantrill LA, Chin V, Nagrial AM, Pajic M, Scarlett CJ, Pinho A, Rooman I, Toon C, Wu J, Pinese M, Cowley M, Barbour A, Mawson A, Humphrey ES, Colvin EK, Chou A, Lovell JA, Jamieson NB, Duthie F, Gingras MC, Fisher WE, Dagg RA, Lau LMS, Lee M, Pickett HA, Reddel RR, Samra JS, Kench JG, Merrett ND, Epari K, Nguyen NQ, Zeps N, Falconi M, Simbolo M, Butturini G, Van Buren G, Partelli S, Fassan M; Australian Pancreatic Cancer Genome Initiative, Khanna KK, Gill AJ, Wheeler DA, Gibbs RA, Musgrove EA, Bassi C, Tortora G, Pederzoli P, Pearson JV, Waddell N, Biankin AV, Grimmond SM.

Nature. 2017 Oct 26;550(7677):548. doi: 10.1038/nature24026. Epub 2017 Sep 27.

PMID:
28953865
12.

BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres.

Sobinoff AP, Allen JA, Neumann AA, Yang SF, Walsh ME, Henson JD, Reddel RR, Pickett HA.

EMBO J. 2017 Oct 2;36(19):2907-2919. doi: 10.15252/embj.201796889. Epub 2017 Sep 6.

13.

Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres.

Dagg RA, Pickett HA, Neumann AA, Napier CE, Henson JD, Teber ET, Arthur JW, Reynolds CP, Murray J, Haber M, Sobinoff AP, Lau LMS, Reddel RR.

Cell Rep. 2017 Jun 20;19(12):2544-2556. doi: 10.1016/j.celrep.2017.05.087.

14.

Whole-genome landscapes of major melanoma subtypes.

Hayward NK, Wilmott JS, Waddell N, Johansson PA, Field MA, Nones K, Patch AM, Kakavand H, Alexandrov LB, Burke H, Jakrot V, Kazakoff S, Holmes O, Leonard C, Sabarinathan R, Mularoni L, Wood S, Xu Q, Waddell N, Tembe V, Pupo GM, De Paoli-Iseppi R, Vilain RE, Shang P, Lau LMS, Dagg RA, Schramm SJ, Pritchard A, Dutton-Regester K, Newell F, Fitzgerald A, Shang CA, Grimmond SM, Pickett HA, Yang JY, Stretch JR, Behren A, Kefford RF, Hersey P, Long GV, Cebon J, Shackleton M, Spillane AJ, Saw RPM, López-Bigas N, Pearson JV, Thompson JF, Scolyer RA, Mann GJ.

Nature. 2017 May 11;545(7653):175-180. doi: 10.1038/nature22071. Epub 2017 May 3.

PMID:
28467829
15.

Whole-genome landscape of pancreatic neuroendocrine tumours.

Scarpa A, Chang DK, Nones K, Corbo V, Patch AM, Bailey P, Lawlor RT, Johns AL, Miller DK, Mafficini A, Rusev B, Scardoni M, Antonello D, Barbi S, Sikora KO, Cingarlini S, Vicentini C, McKay S, Quinn MC, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, McLean S, Nourse C, Nourbakhsh E, Wilson PJ, Anderson MJ, Fink JL, Newell F, Waddell N, Holmes O, Kazakoff SH, Leonard C, Wood S, Xu Q, Nagaraj SH, Amato E, Dalai I, Bersani S, Cataldo I, Dei Tos AP, Capelli P, Davì MV, Landoni L, Malpaga A, Miotto M, Whitehall VL, Leggett BA, Harris JL, Harris J, Jones MD, Humphris J, Chantrill LA, Chin V, Nagrial AM, Pajic M, Scarlett CJ, Pinho A, Rooman I, Toon C, Wu J, Pinese M, Cowley M, Barbour A, Mawson A, Humphrey ES, Colvin EK, Chou A, Lovell JA, Jamieson NB, Duthie F, Gingras MC, Fisher WE, Dagg RA, Lau LM, Lee M, Pickett HA, Reddel RR, Samra JS, Kench JG, Merrett ND, Epari K, Nguyen NQ, Zeps N, Falconi M, Simbolo M, Butturini G, Van Buren G, Partelli S, Fassan M; Australian Pancreatic Cancer Genome Initiative, Khanna KK, Gill AJ, Wheeler DA, Gibbs RA, Musgrove EA, Bassi C, Tortora G, Pederzoli P, Pearson JV, Waddell N, Biankin AV, Grimmond SM.

Nature. 2017 Mar 2;543(7643):65-71. doi: 10.1038/nature21063. Epub 2017 Feb 15. Erratum in: Nature. 2017 Sep 27;:.

PMID:
28199314
16.

Comparative analysis of whole genome sequencing-based telomere length measurement techniques.

Lee M, Napier CE, Yang SF, Arthur JW, Reddel RR, Pickett HA.

Methods. 2017 Feb 1;114:4-15. doi: 10.1016/j.ymeth.2016.08.008. Epub 2016 Aug 24.

PMID:
27565742
17.

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.

O'Brien R, Tran SL, Maritz MF, Liu B, Kong CF, Purgato S, Yang C, Murray J, Russell AJ, Flemming CL, von Jonquieres G, Pickett HA, London WB, Haber M, Gunaratne PH, Norris MD, Perini G, Fletcher JI, MacKenzie KL.

Cancer Res. 2016 Jun 15;76(12):3604-17. doi: 10.1158/0008-5472.CAN-15-0879. Epub 2016 Apr 13.

18.

Molecular mechanisms of activity and derepression of alternative lengthening of telomeres.

Pickett HA, Reddel RR.

Nat Struct Mol Biol. 2015 Nov;22(11):875-80. doi: 10.1038/nsmb.3106. Epub 2015 Nov 4. Review.

PMID:
26581522
19.

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres.

Udugama M, M Chang FT, Chan FL, Tang MC, Pickett HA, R McGhie JD, Mayne L, Collas P, Mann JR, Wong LH.

Nucleic Acids Res. 2015 Dec 2;43(21):10227-37. doi: 10.1093/nar/gkv847. Epub 2015 Aug 24.

20.

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase.

Killedar A, Stutz MD, Sobinoff AP, Tomlinson CG, Bryan TM, Beesley J, Chenevix-Trench G, Reddel RR, Pickett HA.

PLoS Genet. 2015 Jun 8;11(6):e1005286. doi: 10.1371/journal.pgen.1005286. eCollection 2015 Jun.

21.

Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1.

Guo Y, Kartawinata M, Li J, Pickett HA, Teo J, Kilo T, Barbaro PM, Keating B, Chen Y, Tian L, Al-Odaib A, Reddel RR, Christodoulou J, Xu X, Hakonarson H, Bryan TM.

Blood. 2014 Oct 30;124(18):2767-74. doi: 10.1182/blood-2014-08-596445. Epub 2014 Sep 9.

22.

NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.

Conomos D, Reddel RR, Pickett HA.

Nat Struct Mol Biol. 2014 Sep;21(9):760-70. doi: 10.1038/nsmb.2877. Epub 2014 Aug 24.

PMID:
25150861
23.

Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells.

Bull CF, Mayrhofer G, O'Callaghan NJ, Au AY, Pickett HA, Low GK, Zeegers D, Hande MP, Fenech MF.

Cancer Prev Res (Phila). 2014 Jan;7(1):128-38. doi: 10.1158/1940-6207.CAPR-13-0264. Epub 2013 Nov 19.

24.

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes.

Lee M, Hills M, Conomos D, Stutz MD, Dagg RA, Lau LM, Reddel RR, Pickett HA.

Nucleic Acids Res. 2014 Feb;42(3):1733-46. doi: 10.1093/nar/gkt1117. Epub 2013 Nov 12.

25.

The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak.

Kojima Y, Kaufman-Francis K, Studdert JB, Steiner KA, Power MD, Loebel DA, Jones V, Hor A, de Alencastro G, Logan GJ, Teber ET, Tam OH, Stutz MD, Alexander IE, Pickett HA, Tam PP.

Cell Stem Cell. 2014 Jan 2;14(1):107-20. doi: 10.1016/j.stem.2013.09.014. Epub 2013 Oct 17.

26.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S, Baynes C, Bolla MK, Wang Q, Dennis J, McGuffog L, Barrowdale D, Lee A, Healey S, Lush M, Tessier DC, Vincent D, Bacot F; Australian Cancer Study; Australian Ovarian Cancer Study; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab); Gene Environment Interaction and Breast Cancer (GENICA); Swedish Breast Cancer Study (SWE-BRCA); Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE); Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO), Vergote I, Lambrechts S, Despierre E, Risch HA, González-Neira A, Rossing MA, Pita G, Doherty JA, Alvarez N, Larson MC, Fridley BL, Schoof N, Chang-Claude J, Cicek MS, Peto J, Kalli KR, Broeks A, Armasu SM, Schmidt MK, Braaf LM, Winterhoff B, Nevanlinna H, Konecny GE, Lambrechts D, Rogmann L, Guénel P, Teoman A, Milne RL, Garcia JJ, Cox A, Shridhar V, Burwinkel B, Marme F, Hein R, Sawyer EJ, Haiman CA, Wang-Gohrke S, Andrulis IL, Moysich KB, Hopper JL, Odunsi K, Lindblom A, Giles GG, Brenner H, Simard J, Lurie G, Fasching PA, Carney ME, Radice P, Wilkens LR, Swerdlow A, Goodman MT, Brauch H, Garcia-Closas M, Hillemanns P, Winqvist R, Dürst M, Devilee P, Runnebaum I, Jakubowska A, Lubinski J, Mannermaa A, Butzow R, Bogdanova NV, Dörk T, Pelttari LM, Zheng W, Leminen A, Anton-Culver H, Bunker CH, Kristensen V, Ness RB, Muir K, Edwards R, Meindl A, Heitz F, Matsuo K, du Bois A, Wu AH, Harter P, Teo SH, Schwaab I, Shu XO, Blot W, Hosono S, Kang D, Nakanishi T, Hartman M, Yatabe Y, Hamann U, Karlan BY, Sangrajrang S, Kjaer SK, Gaborieau V, Jensen A, Eccles D, Høgdall E, Shen CY, Brown J, Woo YL, Shah M, Azmi MA, Luben R, Omar SZ, Czene K, Vierkant RA, Nordestgaard BG, Flyger H, Vachon C, Olson JE, Wang X, Levine DA, Rudolph A, Weber RP, Flesch-Janys D, Iversen E, Nickels S, Schildkraut JM, Silva Idos S, Cramer DW, Gibson L, Terry KL, Fletcher O, Vitonis AF, van der Schoot CE, Poole EM, Hogervorst FB, Tworoger SS, Liu J, Bandera EV, Li J, Olson SH, Humphreys K, Orlow I, Blomqvist C, Rodriguez-Rodriguez L, Aittomäki K, Salvesen HB, Muranen TA, Wik E, Brouwers B, Krakstad C, Wauters E, Halle MK, Wildiers H, Kiemeney LA, Mulot C, Aben KK, Laurent-Puig P, Altena AM, Truong T, Massuger LF, Benitez J, Pejovic T, Perez JI, Hoatlin M, Zamora MP, Cook LS, Balasubramanian SP, Kelemen LE, Schneeweiss A, Le ND, Sohn C, Brooks-Wilson A, Tomlinson I, Kerin MJ, Miller N, Cybulski C, Henderson BE, Menkiszak J, Schumacher F, Wentzensen N, Le Marchand L, Yang HP, Mulligan AM, Glendon G, Engelholm SA, Knight JA, Høgdall CK, Apicella C, Gore M, Tsimiklis H, Song H, Southey MC, Jager A, den Ouweland AM, Brown R, Martens JW, Flanagan JM, Kriege M, Paul J, Margolin S, Siddiqui N, Severi G, Whittemore AS, Baglietto L, McGuire V, Stegmaier C, Sieh W, Müller H, Arndt V, Labrèche F, Gao YT, Goldberg MS, Yang G, Dumont M, McLaughlin JR, Hartmann A, Ekici AB, Beckmann MW, Phelan CM, Lux MP, Permuth-Wey J, Peissel B, Sellers TA, Ficarazzi F, Barile M, Ziogas A, Ashworth A, Gentry-Maharaj A, Jones M, Ramus SJ, Orr N, Menon U, Pearce CL, Brüning T, Pike MC, Ko YD, Lissowska J, Figueroa J, Kupryjanczyk J, Chanock SJ, Dansonka-Mieszkowska A, Jukkola-Vuorinen A, Rzepecka IK, Pylkäs K, Bidzinski M, Kauppila S, Hollestelle A, Seynaeve C, Tollenaar RA, Durda K, Jaworska K, Hartikainen JM, Kosma VM, Kataja V, Antonenkova NN, Long J, Shrubsole M, Deming-Halverson S, Lophatananon A, Siriwanarangsan P, Stewart-Brown S, Ditsch N, Lichtner P, Schmutzler RK, Ito H, Iwata H, Tajima K, Tseng CC, Stram DO, van den Berg D, Yip CH, Ikram MK, Teh YC, Cai H, Lu W, Signorello LB, Cai Q, Noh DY, Yoo KY, Miao H, Iau PT, Teo YY, McKay J, Shapiro C, Ademuyiwa F, Fountzilas G, Hsiung CN, Yu JC, Hou MF, Healey CS, Luccarini C, Peock S, Stoppa-Lyonnet D, Peterlongo P, Rebbeck TR, Piedmonte M, Singer CF, Friedman E, Thomassen M, Offit K, Hansen TV, Neuhausen SL, Szabo CI, Blanco I, Garber J, Narod SA, Weitzel JN, Montagna M, Olah E, Godwin AK, Yannoukakos D, Goldgar DE, Caldes T, Imyanitov EN, Tihomirova L, Arun BK, Campbell I, Mensenkamp AR, van Asperen CJ, van Roozendaal KE, Meijers-Heijboer H, Collée JM, Oosterwijk JC, Hooning MJ, Rookus MA, van der Luijt RB, Os TA, Evans DG, Frost D, Fineberg E, Barwell J, Walker L, Kennedy MJ, Platte R, Davidson R, Ellis SD, Cole T, Bressac-de Paillerets B, Buecher B, Damiola F, Faivre L, Frenay M, Sinilnikova OM, Caron O, Giraud S, Mazoyer S, Bonadona V, Caux-Moncoutier V, Toloczko-Grabarek A, Gronwald J, Byrski T, Spurdle AB, Bonanni B, Zaffaroni D, Giannini G, Bernard L, Dolcetti R, Manoukian S, Arnold N, Engel C, Deissler H, Rhiem K, Niederacher D, Plendl H, Sutter C, Wappenschmidt B, Borg A, Melin B, Rantala J, Soller M, Nathanson KL, Domchek SM, Rodriguez GC, Salani R, Kaulich DG, Tea MK, Paluch SS, Laitman Y, Skytte AB, Kruse TA, Jensen UB, Robson M, Gerdes AM, Ejlertsen B, Foretova L, Savage SA, Lester J, Soucy P, Kuchenbaecker KB, Olswold C, Cunningham JM, Slager S, Pankratz VS, Dicks E, Lakhani SR, Couch FJ, Hall P, Monteiro AN, Gayther SA, Pharoah PD, Reddel RR, Goode EL, Greene MH, Easton DF, Berchuck A, Antoniou AC, Chenevix-Trench G, Dunning AM.

Nat Genet. 2013 Apr;45(4):371-84, 384e1-2. doi: 10.1038/ng.2566.

27.

Alternative lengthening of telomeres: remodeling the telomere architecture.

Conomos D, Pickett HA, Reddel RR.

Front Oncol. 2013 Feb 20;3:27. doi: 10.3389/fonc.2013.00027. eCollection 2013.

28.

Alternative lengthening of telomeres in normal mammalian somatic cells.

Neumann AA, Watson CM, Noble JR, Pickett HA, Tam PP, Reddel RR.

Genes Dev. 2013 Jan 1;27(1):18-23. doi: 10.1101/gad.205062.112.

29.

Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells.

Conomos D, Stutz MD, Hills M, Neumann AA, Bryan TM, Reddel RR, Pickett HA.

J Cell Biol. 2012 Dec 10;199(6):893-906. doi: 10.1083/jcb.201207189.

30.

Extreme telomere length dimorphism in the Tasmanian devil and related marsupials suggests parental control of telomere length.

Bender HS, Murchison EP, Pickett HA, Deakin JE, Strong MA, Conlan C, McMillan DA, Neumann AA, Greider CW, Hannon GJ, Reddel RR, Graves JA.

PLoS One. 2012;7(9):e46195. doi: 10.1371/journal.pone.0046195. Epub 2012 Sep 25.

31.

RTEL1 contributes to DNA replication and repair and telomere maintenance.

Uringa EJ, Lisaingo K, Pickett HA, Brind'Amour J, Rohde JH, Zelensky A, Essers J, Lansdorp PM.

Mol Biol Cell. 2012 Jul;23(14):2782-92. doi: 10.1091/mbc.E12-03-0179. Epub 2012 May 16.

32.

Telomerase recruitment requires both TCAB1 and Cajal bodies independently.

Stern JL, Zyner KG, Pickett HA, Cohen SB, Bryan TM.

Mol Cell Biol. 2012 Jul;32(13):2384-95. doi: 10.1128/MCB.00379-12. Epub 2012 Apr 30.

33.

The role of telomere trimming in normal telomere length dynamics.

Pickett HA, Reddel RR.

Cell Cycle. 2012 Apr 1;11(7):1309-15. doi: 10.4161/cc.19632. Epub 2012 Apr 1. Review.

PMID:
22421147
34.

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers.

Beesley J, Pickett HA, Johnatty SE, Dunning AM, Chen X, Li J, Michailidou K, Lu Y, Rider DN, Palmieri RT, Stutz MD, Lambrechts D, Despierre E, Lambrechts S, Vergote I, Chang-Claude J, Nickels S, Vrieling A, Flesch-Janys D, Wang-Gohrke S, Eilber U, Bogdanova N, Antonenkova N, Runnebaum IB, Dörk T, Goodman MT, Lurie G, Wilkens LR, Matsuno RK, Kiemeney LA, Aben KK, Marees T, Massuger LF, Fridley BL, Vierkant RA, Bandera EV, Olson SH, Orlow I, Rodriguez-Rodriguez L, Cook LS, Le ND, Brooks-Wilson A, Kelemen LE, Campbell I, Gayther SA, Ramus SJ, Gentry-Maharaj A, Menon U, Ahmed S, Baynes C, Pharoah PD; kConFab Investigators; Australian Ovarian Cancer Study Group; ABCTB Investigators, Muir K, Lophatananon A, Chaiwerawattana A, Wiangnon S, Macgregor S, Easton DF, Reddel RR, Goode EL, Chenevix-Trench G; Ovarian Cancer Association Consortium.

PLoS One. 2011;6(9):e24987. doi: 10.1371/journal.pone.0024987. Epub 2011 Sep 15.

35.

Normal mammalian cells negatively regulate telomere length by telomere trimming.

Pickett HA, Henson JD, Au AY, Neumann AA, Reddel RR.

Hum Mol Genet. 2011 Dec 1;20(23):4684-92. doi: 10.1093/hmg/ddr402. Epub 2011 Sep 8.

PMID:
21903669
36.

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

Cesare AJ, Kaul Z, Cohen SB, Napier CE, Pickett HA, Neumann AA, Reddel RR.

Nat Struct Mol Biol. 2009 Dec;16(12):1244-51. doi: 10.1038/nsmb.1725. Epub 2009 Nov 22.

PMID:
19935685
37.

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.

Henson JD, Cao Y, Huschtscha LI, Chang AC, Au AY, Pickett HA, Reddel RR.

Nat Biotechnol. 2009 Dec;27(12):1181-5. doi: 10.1038/nbt.1587.

PMID:
19935656
38.

Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline.

Mendez-Bermudez A, Hills M, Pickett HA, Phan AT, Mergny JL, Riou JF, Royle NJ.

Nucleic Acids Res. 2009 Oct;37(18):6225-38. doi: 10.1093/nar/gkp629. Epub 2009 Aug 5.

39.

Control of telomere length by a trimming mechanism that involves generation of t-circles.

Pickett HA, Cesare AJ, Johnston RL, Neumann AA, Reddel RR.

EMBO J. 2009 Apr 8;28(7):799-809. doi: 10.1038/emboj.2009.42. Epub 2009 Feb 12.

40.

Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription.

Ng LJ, Cropley JE, Pickett HA, Reddel RR, Suter CM.

Nucleic Acids Res. 2009 Mar;37(4):1152-9. doi: 10.1093/nar/gkn1030. Epub 2009 Jan 7.

41.

Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels.

Cao Y, Huschtscha LI, Nouwens AS, Pickett HA, Neumann AA, Chang AC, Toouli CD, Bryan TM, Reddel RR.

Cancer Res. 2008 May 1;68(9):3115-23. doi: 10.1158/0008-5472.CAN-07-6377.

42.

DBC1 re-expression alters the expression of multiple components of the plasminogen pathway.

Louhelainen JP, Hurst CD, Pitt E, Nishiyama H, Pickett HA, Knowles MA.

Oncogene. 2006 Apr 13;25(16):2409-19.

PMID:
16369496
43.

Telomere instability detected in sporadic colon cancers, some showing mutations in a mismatch repair gene.

Pickett HA, Baird DM, Hoff-Olsen P, Meling GI, Rognum TO, Shaw J, West KP, Royle NJ.

Oncogene. 2004 Apr 22;23(19):3434-43.

PMID:
15048084
44.

Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells.

Varley H, Pickett HA, Foxon JL, Reddel RR, Royle NJ.

Nat Genet. 2002 Mar;30(3):301-5. Epub 2002 Feb 4.

PMID:
11919561

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