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Items: 18

1.

Tracking Metabolic Rewiring of Cancer Metabolism in Humans Using Isotope-Resolved NMR.

Pichumani K.

Methods Mol Biol. 2019;2037:169-186. doi: 10.1007/978-1-4939-9690-2_10.

PMID:
31463845
2.

Ex Vivo 1H NMR study of pituitary adenomas to differentiate various immunohistochemical subtypes.

Ijare OB, Baskin DS, Pichumani K.

Sci Rep. 2019 Feb 28;9(1):3007. doi: 10.1038/s41598-019-38542-6.

3.

Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency.

Jakkamsetti V, Marin-Valencia I, Ma Q, Good LB, Terrill T, Rajasekaran K, Pichumani K, Khemtong C, Hooshyar MA, Sundarrajan C, Patel MS, Bachoo RM, Malloy CR, Pascual JM.

Sci Transl Med. 2019 Feb 20;11(480). pii: eaan0457. doi: 10.1126/scitranslmed.aan0457.

PMID:
30787166
4.

Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo.

Courtney KD, Bezwada D, Mashimo T, Pichumani K, Vemireddy V, Funk AM, Wimberly J, McNeil SS, Kapur P, Lotan Y, Margulis V, Cadeddu JA, Pedrosa I, DeBerardinis RJ, Malloy CR, Bachoo RM, Maher EA.

Cell Metab. 2018 Nov 6;28(5):793-800.e2. doi: 10.1016/j.cmet.2018.07.020. Epub 2018 Aug 23.

5.

Metabolism of fructose in B-cells: A 13C NMR spectroscopy based stable isotope tracer study.

Ijare OB, Baskin DS, Sharpe MA, Pichumani K.

Anal Biochem. 2018 Jul 1;552:110-117. doi: 10.1016/j.ab.2018.04.003. Epub 2018 Apr 11.

PMID:
29654744
6.

Measurement of 13 C turnover into glutamate and glutamine pools in brain tumor patients.

Pichumani K, Mashimo T, Vemireddy V, Ijare OB, Mickey BE, Malloy CR, Marin-Valencia I, Baskin DS, Bachoo RM, Maher EA.

FEBS Lett. 2017 Nov;591(21):3548-3554. doi: 10.1002/1873-3468.12867. Epub 2017 Oct 27.

7.

Elucidating the structural organization of a novel low-density lipoprotein nanoparticle reconstituted with docosahexaenoic acid.

Mulik RS, Zheng H, Pichumani K, Ratnakar J, Jiang QX, Corbin IR.

Chem Phys Lipids. 2017 Apr;204:65-75. doi: 10.1016/j.chemphyslip.2017.03.007. Epub 2017 Mar 22.

8.

Hepatic gluconeogenesis influences (13)C enrichment in lactate in human brain tumors during metabolism of [1,2-(13)C]acetate.

Pichumani K, Mashimo T, Vemireddy V, Kovacs Z, Ratnakar J, Mickey B, Malloy CR, DeBerardinis RJ, Bachoo RM, Maher EA.

Neurochem Int. 2016 Jul;97:133-6. doi: 10.1016/j.neuint.2016.03.015. Epub 2016 Mar 26.

9.

Novel application of complementary imaging techniques to examine in vivo glucose metabolism in the kidney.

Hato T, Friedman AN, Mang H, Plotkin Z, Dube S, Hutchins GD, Territo PR, McCarthy BP, Riley AA, Pichumani K, Malloy CR, Harris RA, Dagher PC, Sutton TA.

Am J Physiol Renal Physiol. 2016 Apr 15;310(8):F717-F725. doi: 10.1152/ajprenal.00535.2015. Epub 2016 Jan 13.

10.

Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas.

Pichumani K, Mashimo T, Baek HM, Ratnakar J, Mickey B, DeBerardinis RJ, Maher EA, Bachoo RM, Malloy CR, Kovacs Z.

Anal Biochem. 2015 Jul 15;481:4-6. doi: 10.1016/j.ab.2015.04.017. Epub 2015 Apr 20.

11.

Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.

Mashimo T, Pichumani K, Vemireddy V, Hatanpaa KJ, Singh DK, Sirasanagandla S, Nannepaga S, Piccirillo SG, Kovacs Z, Foong C, Huang Z, Barnett S, Mickey BE, DeBerardinis RJ, Tu BP, Maher EA, Bachoo RM.

Cell. 2014 Dec 18;159(7):1603-14. doi: 10.1016/j.cell.2014.11.025.

12.

The ratio of acetate-to-glucose oxidation in astrocytes from a single 13C NMR spectrum of cerebral cortex.

Marin-Valencia I, Hooshyar MA, Pichumani K, Sherry AD, Malloy CR.

J Neurochem. 2015 Jan;132(1):99-109. doi: 10.1111/jnc.12948. Epub 2014 Oct 14.

13.

A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.

Choi C, Ganji S, Hulsey K, Madan A, Kovacs Z, Dimitrov I, Zhang S, Pichumani K, Mendelsohn D, Mickey B, Malloy C, Bachoo R, Deberardinis R, Maher E.

NMR Biomed. 2013 Oct;26(10):1242-50. doi: 10.1002/nbm.2943. Epub 2013 Apr 17.

14.

Determination of 15N chemical shift anisotropy from a membrane-bound protein by NMR spectroscopy.

Pandey MK, Vivekanandan S, Ahuja S, Pichumani K, Im SC, Waskell L, Ramamoorthy A.

J Phys Chem B. 2012 Jun 21;116(24):7181-9. doi: 10.1021/jp3049229. Epub 2012 Jun 4.

15.
17.

Covariation of backbone motion throughout a small protein domain.

Mayer KL, Earley MR, Gupta S, Pichumani K, Regan L, Stone MJ.

Nat Struct Biol. 2003 Nov;10(11):962-5. Epub 2003 Oct 5.

PMID:
14528292
18.

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