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Items: 1 to 50 of 297

1.

Immune pathomechanism and classification of drug hypersensitivity.

Pichler WJ.

Allergy. 2019 Aug;74(8):1457-1471. doi: 10.1111/all.13765. Epub 2019 Apr 29. Review.

PMID:
30843233
2.

Controversies in drug allergy: In vitro testing.

Mayorga C, Ebo DG, Lang DM, Pichler WJ, Sabato V, Park MA, Makowska J, Atanaskovic-Markovic M, Bonadonna P, Jares E.

J Allergy Clin Immunol. 2019 Jan;143(1):56-65. doi: 10.1016/j.jaci.2018.09.022. Epub 2018 Dec 17. Review.

PMID:
30573343
3.

Drug hypersensitivity: We need to do more.

Pichler WJ, Yerly D.

J Allergy Clin Immunol. 2018 Jan;141(1):89-91. doi: 10.1016/j.jaci.2017.11.002. Epub 2017 Nov 16. No abstract available.

PMID:
29155149
4.

Medikamentöse Hepatopathien.

Krähenbühl S, Pichler WJ.

Ther Umsch. 2017 Jul;74(3):123-130. doi: 10.1024/0040-5930/a000895. Review. German. No abstract available.

PMID:
28777047
5.

Multiple Drug Hypersensitivity.

Pichler WJ, Srinoulprasert Y, Yun J, Hausmann O.

Int Arch Allergy Immunol. 2017;172(3):129-138. doi: 10.1159/000458725. Epub 2017 Mar 18. Review.

6.

Cardiac involvement in DRESS syndrome.

Thongsri T, Chularojanamontri L, Pichler WJ.

Asian Pac J Allergy Immunol. 2017 Mar;35(1):3-10. doi: 10.12932/AP0847. Review.

7.

Classification of Drug Hypersensitivity into Allergic, p-i, and Pseudo-Allergic Forms.

Pichler WJ, Hausmann O.

Int Arch Allergy Immunol. 2016;171(3-4):166-179. doi: 10.1159/000453265. Epub 2016 Dec 14. Review.

8.

T-cell-mediated drug hypersensitivity: immune mechanisms and their clinical relevance.

Yun J, Cai F, Lee FJ, Pichler WJ.

Asia Pac Allergy. 2016 Apr;6(2):77-89. doi: 10.5415/apallergy.2016.6.2.77. Epub 2016 Apr 28. Review.

9.

Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors.

Pichler WJ, Adam J, Watkins S, Wuillemin N, Yun J, Yerly D.

Int Arch Allergy Immunol. 2015;168(1):13-24. doi: 10.1159/000441280. Epub 2015 Nov 3. Review.

10.

Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.

Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA.

J Allergy Clin Immunol. 2015 Aug;136(2):262-71.e2. doi: 10.1016/j.jaci.2015.05.027.

11.

Abacavir induced T cell reactivity from drug naïve individuals shares features of allo-immune responses.

Adam J, Wuillemin N, Watkins S, Jamin H, Eriksson KK, Villiger P, Fontana S, Pichler WJ, Yerly D.

PLoS One. 2014 Apr 21;9(4):e95339. doi: 10.1371/journal.pone.0095339. eCollection 2014.

12.

T cells infiltrate the liver and kill hepatocytes in HLA-B(∗)57:01-associated floxacillin-induced liver injury.

Wuillemin N, Terracciano L, Beltraminelli H, Schlapbach C, Fontana S, Krähenbühl S, Pichler WJ, Yerly D.

Am J Pathol. 2014 Jun;184(6):1677-82. doi: 10.1016/j.ajpath.2014.02.018. Epub 2014 Apr 13.

PMID:
24731753
13.

Oxypurinol directly and immediately activates the drug-specific T cells via the preferential use of HLA-B*58:01.

Yun J, Marcaida MJ, Eriksson KK, Jamin H, Fontana S, Pichler WJ, Yerly D.

J Immunol. 2014 Apr 1;192(7):2984-93. doi: 10.4049/jimmunol.1302306. Epub 2014 Mar 3.

14.

Enhancement of drug-specific lymphocyte proliferation using CD25(hi)-depleted CD3(+) effector cells.

Srinoulprasert Y, Pichler WJ.

Int Arch Allergy Immunol. 2014;163(3):198-205. doi: 10.1159/000358491. Epub 2014 Feb 13.

PMID:
24525750
15.

Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response.

Yun J, Mattsson J, Schnyder K, Fontana S, Largiadèr CR, Pichler WJ, Yerly D.

Clin Exp Allergy. 2013 Nov;43(11):1246-55. doi: 10.1111/cea.12184.

PMID:
24152157
16.

Sulfamethoxazole induces a switch mechanism in T cell receptors containing TCRVβ20-1, altering pHLA recognition.

Watkins S, Pichler WJ.

PLoS One. 2013 Oct 7;8(10):e76211. doi: 10.1371/journal.pone.0076211. eCollection 2013.

17.

In vitro drug causality assessment in Stevens-Johnson syndrome - alternatives for lymphocyte transformation test.

Porebski G, Pecaric-Petkovic T, Groux-Keller M, Bosak M, Kawabata TT, Pichler WJ.

Clin Exp Allergy. 2013 Sep;43(9):1027-37. doi: 10.1111/cea.12145.

PMID:
23957338
18.

HLA-B*57:01(+) abacavir-naive individuals have specific T cells but no patch test reactivity.

Schnyder B, Adam J, Rauch A, Thurnheer MC, Pichler WJ.

J Allergy Clin Immunol. 2013 Sep;132(3):756-758. doi: 10.1016/j.jaci.2013.04.013. Epub 2013 May 23. No abstract available.

PMID:
23706613
19.

Intravenous immunoglobulin in urticaria.

Jandus P, Hausmann O, Pichler WJ, Helbling A.

J Investig Allergol Clin Immunol. 2013;23(1):71-3. No abstract available.

20.

HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin.

Wuillemin N, Adam J, Fontana S, Krähenbühl S, Pichler WJ, Yerly D.

J Immunol. 2013 May 15;190(10):4956-64. doi: 10.4049/jimmunol.1202949. Epub 2013 Apr 17.

21.

Allergy workup of severe cutaneous adverse drug reactions: a light at the end of the tunnel?

Schnyder B, Porebski G, Pichler WJ.

Br J Dermatol. 2013 Mar;168(3):463-4. doi: 10.1111/bjd.12253. No abstract available.

PMID:
23445307
22.

Allergy to sulfonamides.

Schnyder B, Pichler WJ.

J Allergy Clin Immunol. 2013 Jan;131(1):256-7.e1-5. doi: 10.1016/j.jaci.2012.10.003. No abstract available.

PMID:
23265699
23.

Human leukocyte antigens (HLA) associated drug hypersensitivity: consequences of drug binding to HLA.

Yun J, Adam J, Yerly D, Pichler WJ.

Allergy. 2012 Nov;67(11):1338-46. doi: 10.1111/all.12008. Epub 2012 Sep 3. Review.

PMID:
22943588
24.

Etiology and pathogenesis of adverse drug reactions.

Hausmann O, Schnyder B, Pichler WJ.

Chem Immunol Allergy. 2012;97:32-46. doi: 10.1159/000335614. Epub 2012 May 3.

PMID:
22613852
25.

Avidity determines T-cell reactivity in abacavir hypersensitivity.

Adam J, Eriksson KK, Schnyder B, Fontana S, Pichler WJ, Yerly D.

Eur J Immunol. 2012 Jul;42(7):1706-16. doi: 10.1002/eji.201142159. Epub 2012 Jun 14.

26.

Nonimmediate drug allergy: diagnostic benefit of skin testing and practical approach.

Schnyder B, Pichler WJ.

J Allergy Clin Immunol. 2012 Apr;129(4):1170-1. doi: 10.1016/j.jaci.2012.02.029. No abstract available.

PMID:
22464676
27.

Continuous apple consumption induces oral tolerance in birch-pollen-associated apple allergy.

Kopac P, Rudin M, Gentinetta T, Gerber R, Pichler Ch, Hausmann O, Schnyder B, Pichler WJ.

Allergy. 2012 Feb;67(2):280-5. doi: 10.1111/j.1398-9995.2011.02744.x. Epub 2011 Nov 10.

PMID:
22070352
28.

Multiple drug hypersensitivity: normal Treg cell function but enhanced in vivo activation of drug-specific T cells.

Daubner B, Groux-Keller M, Hausmann OV, Kawabata T, Naisbitt DJ, Park BK, Wendland T, Lerch M, Pichler WJ.

Allergy. 2012 Jan;67(1):58-66. doi: 10.1111/j.1398-9995.2011.02720.x. Epub 2011 Sep 21.

PMID:
21933197
29.

Individual IL-3 priming is crucial for consistent in vitro activation of donor basophils in patients with chronic urticaria.

Gentinetta T, Pecaric-Petkovic T, Wan D, Falcone FH, Dahinden CA, Pichler WJ, Hausmann OV.

J Allergy Clin Immunol. 2011 Dec;128(6):1227-1234.e5. doi: 10.1016/j.jaci.2011.07.021. Epub 2011 Sep 8.

PMID:
21855127
30.

NKp46+ cells express granulysin in multiple cutaneous adverse drug reactions.

Schlapbach C, Zawodniak A, Irla N, Adam J, Hunger RE, Yerly D, Pichler WJ, Yawalkar N.

Allergy. 2011 Nov;66(11):1469-76. doi: 10.1111/j.1398-9995.2011.02677.x. Epub 2011 Aug 5.

PMID:
21819408
31.

Educational case series: Mechanisms of drug allergy.

Caubet JC, Pichler WJ, Eigenmann PA.

Pediatr Allergy Immunol. 2011 Sep;22(6):559-67. doi: 10.1111/j.1399-3038.2011.01183.x. Epub 2011 Jun 6. Review.

PMID:
21645118
32.

Delayed drug hypersensitivity: models of T-cell stimulation.

Adam J, Pichler WJ, Yerly D.

Br J Clin Pharmacol. 2011 May;71(5):701-7. doi: 10.1111/j.1365-2125.2010.03764.x. Review.

33.

Immune pathomechanism of drug hypersensitivity reactions.

Pichler WJ, Naisbitt DJ, Park BK.

J Allergy Clin Immunol. 2011 Mar;127(3 Suppl):S74-81. doi: 10.1016/j.jaci.2010.11.048.

PMID:
21354503
34.

Highlights of the 4th Drug Hypersensitivity Meeting--Rome, April 22-25, 2010. Preface.

Romano A, Pichler WJ, Blanca M.

J Allergy Clin Immunol. 2011 Mar;127(3 Suppl):S59. doi: 10.1016/j.jaci.2010.12.1090. No abstract available.

PMID:
21354500
35.

Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis.

Elsheikh A, Castrejon L, Lavergne SN, Whitaker P, Monshi M, Callan H, El-Ghaiesh S, Farrell J, Pichler WJ, Peckham D, Park BK, Naisbitt DJ.

J Allergy Clin Immunol. 2011 Jun;127(6):1543-51.e3. doi: 10.1016/j.jaci.2010.12.1119. Epub 2011 Feb 26.

PMID:
21354601
36.

Drug hypersensitivity: flare-up reactions, cross-reactivity and multiple drug hypersensitivity.

Pichler WJ, Daubner B, Kawabata T.

J Dermatol. 2011 Mar;38(3):216-21. doi: 10.1111/j.1346-8138.2010.01142.x. Epub 2011 Feb 1.

PMID:
21342222
37.

In vitro diagnosis of T cell-mediated drug allergy.

Porebski G, Gschwend-Zawodniak A, Pichler WJ.

Clin Exp Allergy. 2011 Apr;41(4):461-70. doi: 10.1111/j.1365-2222.2011.03701.x. Epub 2011 Feb 22. Review.

PMID:
21338430
38.

Ceftobiprole associated agranulocytosis after drug rash with eosinophilia and systemic symptoms induced by vancomycin and rifampicin.

Wendland T, Daubner B, Pichler WJ.

Br J Clin Pharmacol. 2011 Feb;71(2):297-300. doi: 10.1111/j.1365-2125.2010.03832.x. No abstract available.

39.

Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism.

Elsheikh A, Lavergne SN, Castrejon JL, Farrell J, Wang H, Sathish J, Pichler WJ, Park BK, Naisbitt DJ.

J Immunol. 2010 Dec 1;185(11):6448-60. doi: 10.4049/jimmunol.1000889. Epub 2010 Oct 27.

40.

T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays.

Martin SF, Esser PR, Schmucker S, Dietz L, Naisbitt DJ, Park BK, Vocanson M, Nicolas JF, Keller M, Pichler WJ, Peiser M, Luch A, Wanner R, Maggi E, Cavani A, Rustemeyer T, Richter A, Thierse HJ, Sallusto F.

Cell Mol Life Sci. 2010 Dec;67(24):4171-84. doi: 10.1007/s00018-010-0495-3. Epub 2010 Aug 18. Review.

PMID:
20717835
41.

General considerations on rapid desensitization for drug hypersensitivity - a consensus statement.

Cernadas JR, Brockow K, Romano A, Aberer W, Torres MJ, Bircher A, Campi P, Sanz ML, Castells M, Demoly P, Pichler WJ; European Network of Drug Allergy and the EAACI interest group on drug hypersensitivity.

Allergy. 2010 Nov;65(11):1357-66. doi: 10.1111/j.1398-9995.2010.02441.x. Epub 2010 Aug 17. Review.

PMID:
20716314
42.

The complex clinical picture of side effects to biologicals.

Hausmann OV, Seitz M, Villiger PM, Pichler WJ.

Med Clin North Am. 2010 Jul;94(4):791-804, xi-ii. doi: 10.1016/j.mcna.2010.03.001. Review.

PMID:
20609863
43.

Drug hypersensitivity reactions: pathomechanism and clinical symptoms.

Pichler WJ, Adam J, Daubner B, Gentinetta T, Keller M, Yerly D.

Med Clin North Am. 2010 Jul;94(4):645-64, xv. doi: 10.1016/j.mcna.2010.04.003. Review.

PMID:
20609855
44.

The area of drug hypersensitivity has been widely neglected not least because it is a complex area. Preface.

Pichler WJ.

Med Clin North Am. 2010 Jul;94(4):xv-vi. doi: 10.1016/j.mcna.2010.04.008. No abstract available.

PMID:
20609854
45.

Robust expression of CCR3 as a single basophil selection marker in flow cytometry.

Hausmann OV, Gentinetta T, Fux M, Ducrest S, Pichler WJ, Dahinden CA.

Allergy. 2011 Jan;66(1):85-91. doi: 10.1111/j.1398-9995.2010.02431.x.

PMID:
20608915
46.

Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole.

Zawodniak A, Lochmatter P, Beeler A, Pichler WJ.

Int Arch Allergy Immunol. 2010;153(2):152-6. doi: 10.1159/000312632. Epub 2010 Apr 22.

47.

Stimulation of human T cells with sulfonamides and sulfonamide metabolites.

Castrejon JL, Berry N, El-Ghaiesh S, Gerber B, Pichler WJ, Park BK, Naisbitt DJ.

J Allergy Clin Immunol. 2010 Feb;125(2):411-418.e4. doi: 10.1016/j.jaci.2009.10.031.

PMID:
20159253
48.

Processing-dependent and -independent pathways for recognition of iodinated contrast media by specific human T cells.

Keller M, Lerch M, Britschgi M, Tâche V, Gerber BO, Lüthi M, Lochmatter P, Kanny G, Bircher AJ, Christiansen C, Pichler WJ.

Clin Exp Allergy. 2010 Feb;40(2):257-68. doi: 10.1111/j.1365-2222.2009.03425.x. Epub 2009 Dec 16.

PMID:
20030663
49.

Drug hypersensitivity reactions involving skin.

Hausmann O, Schnyder B, Pichler WJ.

Handb Exp Pharmacol. 2010;(196):29-55. doi: 10.1007/978-3-642-00663-0_2. Review.

PMID:
20020258
50.

In vitro detection of cytotoxic T and NK cells in peripheral blood of patients with various drug-induced skin diseases.

Zawodniak A, Lochmatter P, Yerly D, Kawabata T, Lerch M, Yawalkar N, Pichler WJ.

Allergy. 2010 Mar;65(3):376-84. doi: 10.1111/j.1398-9995.2009.02180.x. Epub 2009 Sep 30.

PMID:
19793058

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