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Items: 1 to 50 of 332

1.

Comparative Analysis of Microbiome in Nasopharynx and Middle Ear in Young Children With Acute Otitis Media.

Xu Q, Gill S, Xu L, Gonzalez E, Pichichero ME.

Front Genet. 2019 Nov 19;10:1176. doi: 10.3389/fgene.2019.01176. eCollection 2019.

2.

Development and Modification of an Outcome Measure to Follow Symptoms of Children with Sinusitis.

Shaikh N, Wald ER, Jeong JH, Kurs-Lasky M, Nash D, Pichichero ME, Kearney DH, Haralam MA, Bowen A, Flom LL, Hoberman A.

J Pediatr. 2019 Apr;207:103-108.e1. doi: 10.1016/j.jpeds.2018.11.016. Epub 2018 Dec 10.

PMID:
30545562
3.

Impaired Proinflammatory Response in Stringently Defined Otitis-prone Children During Viral Upper Respiratory Infections.

Ren D, Xu Q, Almudevar AL, Pichichero ME.

Clin Infect Dis. 2019 Apr 24;68(9):1566-1574. doi: 10.1093/cid/ciy750.

4.

Helping children with hearing loss from otitis media with effusion.

Pichichero ME.

Lancet. 2018 Aug 18;392(10147):533-534. doi: 10.1016/S0140-6736(18)31862-2. Epub 2018 Aug 16. No abstract available.

5.

Intranasal coinfection model allows for assessment of protein vaccines against nontypeable Haemophilus influenzae in mice.

Michel LV, Kaur R, Zavorin M, Pryharski K, Khan MN, LaClair C, O'Neil M, Xu Q, Pichichero ME.

J Med Microbiol. 2018 Oct;67(10):1527-1532. doi: 10.1099/jmm.0.000827. Epub 2018 Aug 23.

PMID:
30136923
6.

Immunogenicity and protective efficacy of monovalent PCVs containing 22F and 33F polysaccharides in mouse models of colonization and co-infection.

Khan MN, Pryharski K, Pichichero ME.

Vaccine. 2018 Sep 11;36(38):5701-5708. doi: 10.1016/j.vaccine.2018.08.017. Epub 2018 Aug 11.

PMID:
30107993
7.

TLR agonist combinations that stimulate Th type I polarizing responses from human neonates.

Surendran N, Simmons A, Pichichero ME.

Innate Immun. 2018 May;24(4):240-251. doi: 10.1177/1753425918771178. Epub 2018 Apr 19.

8.

Haemophilus influenzae-protein D specific antibody correlate with protection against acute otitis media in young children.

Almudevar A, Pichichero ME.

Vaccine. 2018 Feb 21;36(9):1133-1135. doi: 10.1016/j.vaccine.2018.01.021. Epub 2018 Feb 1.

9.

Pneumococcal whole-cell and protein-based vaccines: changing the paradigm.

Pichichero ME.

Expert Rev Vaccines. 2017 Dec;16(12):1181-1190. doi: 10.1080/14760584.2017.1393335. Review.

10.

Streptococcus pneumoniae burden and nasopharyngeal inflammation during acute otitis media.

Morris MC, Pichichero ME.

Innate Immun. 2017 Nov;23(8):667-677. doi: 10.1177/1753425917737825.

PMID:
29113587
11.

Comparison of direct-plating and broth-enrichment culture methods for detection of potential bacterial pathogens in respiratory secretions.

Kaur R, Wischmeyer J, Morris M, Pichichero ME.

J Med Microbiol. 2017 Nov;66(11):1539-1544. doi: 10.1099/jmm.0.000587. Epub 2017 Oct 16.

PMID:
29034852
12.

Cross-reactivity in β-Lactam Allergy.

Zagursky RJ, Pichichero ME.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):72-81.e1. doi: 10.1016/j.jaip.2017.08.027. Epub 2017 Oct 7. Review.

PMID:
29017833
13.

Decreased TNF family receptor expression on B-cells is associated with reduced humoral responses to Streptococcus pneumoniae infections in young children.

Basha S, Pichichero ME.

Cell Immunol. 2017 Oct;320:11-19. doi: 10.1016/j.cellimm.2017.07.004. Epub 2017 Jul 21.

PMID:
28947093
14.

Modeling specific antibody responses to natural immunization to predict a correlate of protection against infection before commencing a clinical vaccine trial.

Almudevar A, Pichichero ME.

Hum Vaccin Immunother. 2017 Oct 3;13(10):2316-2321. doi: 10.1080/21645515.2017.1329064.

15.

Stringently Defined Otitis Prone Children Demonstrate Deficient Naturally Induced Mucosal Antibody Response to Moraxella catarrhalis Proteins.

Ren D, Murphy TF, Lafontaine ER, Pichichero ME.

Front Immunol. 2017 Aug 11;8:953. doi: 10.3389/fimmu.2017.00953. eCollection 2017.

16.

Epidemiology of Acute Otitis Media in the Postpneumococcal Conjugate Vaccine Era.

Kaur R, Morris M, Pichichero ME.

Pediatrics. 2017 Sep;140(3). pii: e20170181. doi: 10.1542/peds.2017-0181. Epub 2017 Aug 7. Erratum in: Pediatrics. 2018 Feb 28;:.

17.

Serum antibody response to Moraxella catarrhalis proteins in stringently defined otitis prone children.

Ren D, Almudevar AL, Murphy TF, Lafontaine ER, Campagnari AA, Luke-Marshall N, Pichichero ME.

Vaccine. 2019 Jul 26;37(32):4637-4645. doi: 10.1016/j.vaccine.2017.07.027. Epub 2017 Jul 26.

PMID:
28755833
18.

A PCR-based method for quantifying neutrophils in human nasal secretions.

Morris MC, Nadeem Khan M, Pichichero ME.

J Immunol Methods. 2017 Aug;447:65-70. doi: 10.1016/j.jim.2017.04.010. Epub 2017 Apr 26.

19.

Nasopharyngeal polymicrobial colonization during health, viral upper respiratory infection and upper respiratory bacterial infection.

Xu Q, Wischmeyer J, Gonzalez E, Pichichero ME.

J Infect. 2017 Jul;75(1):26-34. doi: 10.1016/j.jinf.2017.04.003. Epub 2017 Apr 13.

20.

Shortened Antimicrobial Treatment for Acute Otitis Media.

Pichichero ME.

N Engl J Med. 2017 Mar 30;376(13):e24. doi: 10.1056/NEJMc1700966. No abstract available.

PMID:
28357845
21.

Reduced T-Helper 17 Responses to Streptococcus pneumoniae in Infection-Prone Children Can Be Rescued by Addition of Innate Cytokines.

Basha S, Kaur R, Mosmann TR, Pichichero ME.

J Infect Dis. 2017 Apr 15;215(8):1321-1330. doi: 10.1093/infdis/jix090.

22.

Correlation of higher antibody levels to pneumococcal proteins with protection from pneumococcal acute otitis media but not protection from nasopharyngeal colonization in young children.

Xu Q, Casey JR, Almudevar A, Pichichero ME.

Clin Microbiol Infect. 2017 Jul;23(7):487.e1-487.e6. doi: 10.1016/j.cmi.2017.01.011. Epub 2017 Jan 28.

23.

Trivalent pneumococcal protein vaccine protects against experimental acute otitis media caused by Streptococcus pneumoniae in an infant murine model.

Xu Q, Pryharski K, Pichichero ME.

Vaccine. 2017 Jan 5;35(2):337-344. doi: 10.1016/j.vaccine.2016.11.046. Epub 2016 Dec 3.

PMID:
27919628
24.
25.

Inflammation-associated cytokine analysis identifies presence of respiratory bacterial pathogens in the nasopharynx.

Pichichero ME, Almudevar A.

Pathog Dis. 2016 Aug;74(6). pii: ftw064. doi: 10.1093/femspd/ftw064. Epub 2016 Aug 4.

26.
27.

Ten-Year Study of the Stringently Defined Otitis-prone Child in Rochester, NY.

Pichichero ME.

Pediatr Infect Dis J. 2016 Sep;35(9):1033-9. doi: 10.1097/INF.0000000000001217. Review.

28.

Ten-Year Study of Acute Otitis Media in Rochester, NY.

Pichichero ME.

Pediatr Infect Dis J. 2016 Sep;35(9):1027-32. doi: 10.1097/INF.0000000000001216. Review.

PMID:
27182898
29.

Serum cytokine biomarkers accurately predict presence of acute otitis media infection and recovery caused by Haemophilus influenzae.

Pichichero ME, Almudevar A.

Int J Pediatr Otorhinolaryngol. 2016 Apr;83:200-4. doi: 10.1016/j.ijporl.2016.02.007. Epub 2016 Feb 12.

PMID:
26968077
30.

Functional Immune Cell Differences Associated With Low Vaccine Responses in Infants.

Pichichero ME, Casey JR, Almudevar A, Basha S, Surendran N, Kaur R, Morris M, Livingstone AM, Mosmann TR.

J Infect Dis. 2016 Jun 15;213(12):2014-9. doi: 10.1093/infdis/jiw053. Epub 2016 Feb 9.

31.

Developing a vaccine to prevent otitis media caused by nontypeable Haemophilus influenzae.

Khan MN, Ren D, Kaur R, Basha S, Zagursky R, Pichichero ME.

Expert Rev Vaccines. 2016 Jul;15(7):863-78. doi: 10.1586/14760584.2016.1156539. Epub 2016 Mar 17. Review.

PMID:
26894630
32.

Peripheral blood antigen presenting cell responses in otitis-prone and non-otitis-prone infants.

Surendran N, Nicolosi T, Kaur R, Pichichero ME.

Innate Immun. 2016 Jan;22(1):63-71. doi: 10.1177/1753425915616267. Epub 2015 Nov 12.

PMID:
26566651
33.

Vaccine targets against Moraxella catarrhalis.

Ren D, Pichichero ME.

Expert Opin Ther Targets. 2016;20(1):19-33. doi: 10.1517/14728222.2015.1081686. Epub 2015 Aug 26. Review.

34.

Next generation protein based Streptococcus pneumoniae vaccines.

Pichichero ME, Khan MN, Xu Q.

Hum Vaccin Immunother. 2016;12(1):194-205. doi: 10.1080/21645515.2015.1052198. Review.

35.

Adenoidal follicular T helper cells provide stronger B-cell help than those from tonsils.

Morris MC, Kozara K, Salamone F, Benoit M, Pichichero ME.

Laryngoscope. 2016 Feb;126(2):E80-5. doi: 10.1002/lary.25536. Epub 2015 Oct 29.

36.

Familial and microbiological contribution to the otitis-prone condition.

Morris MC, Almudevar AL, Casey JR, Pichichero ME.

Int J Pediatr Otorhinolaryngol. 2015 Dec;79(12):2174-7. doi: 10.1016/j.ijporl.2015.09.043. Epub 2015 Oct 13.

37.

Otitis-prone Children Have Immunologic Deficiencies in Naturally Acquired Nasopharyngeal Mucosal Antibody Response after Streptococcus pneumoniae Colonization.

Xu Q, Casey JR, Newman E, Pichichero ME.

Pediatr Infect Dis J. 2016 Jan;35(1):54-60. doi: 10.1097/INF.0000000000000949.

PMID:
26448450
38.

Serum antibody response to Moraxella catarrhalis proteins OMP CD, OppA, Msp22, Hag, and PilA2 after nasopharyngeal colonization and acute otitis media in children.

Ren D, Almudevar AL, Murphy TF, Lafontaine ER, Campagnari AA, Luke-Marshall N, Casey JR, Pichichero ME.

Vaccine. 2015 Oct 26;33(43):5809-5814. doi: 10.1016/j.vaccine.2015.09.023. Epub 2015 Sep 21.

39.

A Reappraisal of the Minimum Duration of Antibiotic Treatment Before Approval of Return to School for Children With Streptococcal Pharyngitis.

Schwartz RH, Kim D, Martin M, Pichichero ME.

Pediatr Infect Dis J. 2015 Dec;34(12):1302-4. doi: 10.1097/INF.0000000000000883.

PMID:
26295745
40.

Poor memory B cell generation contributes to non-protective responses to DTaP vaccine antigens in otitis-prone children.

Basha S, Pichichero ME.

Clin Exp Immunol. 2015 Dec;182(3):314-22. doi: 10.1111/cei.12660. Epub 2015 Sep 30.

41.

Effect of pH and oxygen on biofilm formation in acute otitis media associated NTHi clinical isolates.

Osgood R, Salamone F, Diaz A, Casey JR, Bajorski P, Pichichero ME.

Laryngoscope. 2015 Sep;125(9):2204-8. doi: 10.1002/lary.25102. Epub 2015 May 13.

PMID:
25970856
42.

Antibiotics for children with acute otitis media--reply.

Pichichero ME.

JAMA. 2015 Apr 21;313(15):1575. doi: 10.1001/jama.2015.3083. No abstract available.

PMID:
25898063
43.

Dual orientation of the outer membrane lipoprotein Pal in Escherichia coli.

Michel LV, Shaw J, MacPherson V, Barnard D, Bettinger J, D'Arcy B, Surendran N, Hellman J, Pichichero ME.

Microbiology. 2015 Jun;161(6):1251-9. doi: 10.1099/mic.0.000084. Epub 2015 Mar 25.

44.

Synchrony in serum antibody response to conserved proteins of Streptococcus pneumoniae in young children.

Ren D, Almudevar AL, Pichichero ME.

Hum Vaccin Immunother. 2015;11(2):489-97. doi: 10.4161/21645515.2014.990861.

45.

The host immune dynamics of pneumococcal colonization: implications for novel vaccine development.

Khan MN, Pichichero ME.

Hum Vaccin Immunother. 2014;10(12):3688-99. doi: 10.4161/21645515.2014.979631. Review.

46.
47.

Antibiotics for acute otitis media: yes or no.

Pichichero ME.

JAMA. 2015 Jan 20;313(3):294-5. doi: 10.1001/jama.2014.14990. No abstract available.

PMID:
25603000
48.

Trivalent pneumococcal protein recombinant vaccine protects against lethal Streptococcus pneumoniae pneumonia and correlates with phagocytosis by neutrophils during early pathogenesis.

Xu Q, Surendran N, Verhoeven D, Klapa J, Ochs M, Pichichero ME.

Vaccine. 2015 Feb 18;33(8):993-1000. doi: 10.1016/j.vaccine.2015.01.014. Epub 2015 Jan 15.

PMID:
25597944
49.

Correlation of nasopharyngeal cultures prior to and at onset of acute otitis media with middle ear fluid cultures.

Kaur R, Czup K, Casey JR, Pichichero ME.

BMC Infect Dis. 2014 Dec 5;14:640. doi: 10.1186/s12879-014-0640-y.

50.

Human antibodies to PhtD, PcpA, and Ply reduce adherence to human lung epithelial cells and murine nasopharyngeal colonization by Streptococcus pneumoniae.

Kaur R, Surendran N, Ochs M, Pichichero ME.

Infect Immun. 2014 Dec;82(12):5069-75. doi: 10.1128/IAI.02124-14. Epub 2014 Sep 22.

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