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Impact of Arteriovenous fistula creation on estimated glomerular filtration rate decline in Predialysis patients.

Bénard V, Pichette M, Lafrance JP, Elftouh N, Pichette V, Laurin LP, Nadeau-Fredette AC.

BMC Nephrol. 2019 Nov 25;20(1):420. doi: 10.1186/s12882-019-1607-4.


Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease.

Prokopienko AJ, West RE 3rd, Schrum DP, Stubbs JR, Leblond FA, Pichette V, Nolin TD.

Sci Rep. 2019 Nov 4;9(1):15901. doi: 10.1038/s41598-019-52032-9.


Pharmacodynamics of 250 mg and 500 mg oral furosemide in peritoneal dialysis

Leclerc S, Laurin LP, Lafrance JP, Lamarche C, Ouimet D, Paquette F, Pichette V, Nadeau-Fredette AC.

Int J Clin Pharmacol Ther. 2019 Dec;57(12):603-606. doi: 10.5414/CP203594.


Prospective study of the changes in pharmacokinetics of immunosuppressive medications after laparoscopic sleeve gastrectomy.

Chan G, Hajjar R, Boutin L, Garneau PY, Pichette V, Lafrance JP, Elftouh N, Michaud J, du Souich P.

Am J Transplant. 2019 Sep 17. doi: 10.1111/ajt.15602. [Epub ahead of print]


Effects of Renal Impairment on the Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets.

deVries T, Dentiste A, Di Lea C, Pichette V, Jacobs D.

CNS Drugs. 2019 Aug;33(8):783-789. doi: 10.1007/s40263-019-00651-1.


Clinical Value of Complement Activation Biomarkers in Overt Diabetic Nephropathy.

Pelletier K, Bonnefoy A, Chapdelaine H, Pichette V, Lejars M, Madore F, Brachemi S, Troyanov S.

Kidney Int Rep. 2019 Mar 20;4(6):797-805. doi: 10.1016/j.ekir.2019.03.004. eCollection 2019 Jun.


Rationale for the administration of systemic 5-FU in combination with heated intraperitonal oxaliplatin.

Badrudin D, Sideris L, Leblond FA, Pichette V, Cloutier AS, Drolet P, Dubé P.

Surg Oncol. 2018 Jun;27(2):275-279. doi: 10.1016/j.suronc.2018.05.004. Epub 2018 May 6.


Association of Neutrophil-to-Lymphocyte Ratio With Inflammation and Erythropoietin Resistance in Chronic Dialysis Patients.

Pineault J, Lamarche C, Bell R, Lafrance JP, Ouellet G, Leblanc M, Pichette V, Bezzaoucha S, Vallée M.

Can J Kidney Health Dis. 2017 Nov 3;4:2054358117735563. doi: 10.1177/2054358117735563. eCollection 2017.


The impact of renal protection clinics on prescription of and adherence to cardioprotective drug therapy in chronic kidney disease patients.

Lepeytre F, Cardinal H, Fradette L, Verhave J, Dorais M, LeLorier J, Pichette V, Madore F.

Clin Kidney J. 2017 Jun;10(3):375-380. doi: 10.1093/ckj/sfw144. Epub 2017 Feb 18.


Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes.

Dion F, Dumayne C, Henley N, Beauchemin S, Arias EB, Leblond FA, Lesage S, Lefrançois S, Cartee GD, Pichette V.

PLoS One. 2017 May 1;12(5):e0176650. doi: 10.1371/journal.pone.0176650. eCollection 2017.


Retrospective Study Looking at Cinacalcet in the Management of Hyperparathyroidism after Kidney Transplantation.

Mawad H, Bouchard H, Tran D, Ouimet D, Lafrance JP, Bell RZ, Bezzaoucha S, Boucher A, Collette S, Pichette V, Senécal L, Vallée M.

J Transplant. 2017;2017:8720283. doi: 10.1155/2017/8720283. Epub 2017 Mar 13.


Conversion of oral alfacalcidol to oral calcitriol in the treatment of secondary hyperparathyroidism in chronic hemodialysis patients.

Rauscher S, Lafrance JP, Pichette V, Bell RZ, Desforges K, Lepage L, Ouellet G, Ouimet D, Leblanc M, Lamarche C, Bezzaoucha S, Vallee M.

Int Urol Nephrol. 2017 Feb;49(2):325-328. doi: 10.1007/s11255-016-1446-1. Epub 2016 Nov 8.


Changes in Urinary and Serum Levels of Novel Biomarkers after Administration of Gadolinium-based Contrast Agents.

Mawad H, Laurin LP, Naud JF, Leblond FA, Henley N, Vallée M, Pichette V, Leblanc M.

Biomark Insights. 2016 Jun 29;11:91-4. doi: 10.4137/BMI.S39199. eCollection 2016.


Effects of renal impairment on the pharmacokinetics of orally administered deferiprone.

Fradette C, Pichette V, Sicard É, Stilman A, Jayashankar S, Tsang YC, Spino M, Tricta F.

Br J Clin Pharmacol. 2016 Oct;82(4):994-1001. doi: 10.1111/bcp.13037. Epub 2016 Jul 18.


Effects of Chronic Renal Failure on Brain Cytochrome P450 in Rats.

Naud J, Harding J, Lamarche C, Beauchemin S, Leblond FA, Pichette V.

Drug Metab Dispos. 2016 Aug;44(8):1174-9. doi: 10.1124/dmd.116.070052. Epub 2016 Jun 6.


Pharmacokinetic and Dynamic of Furosemide in Peritoneal Dialysis Patients.

Lamarche C, Pichette M, Ouimet D, Vallée M, Bell R, Ouellet G, Stewart J, Pichette V.

Perit Dial Int. 2016 Jan-Feb;36(1):107-8. doi: 10.3747/pdi.2014.00328.


Validation and Application of a Simple UHPLC-MS-MS Method for the Enantiospecific Determination of Warfarin in Human Urine.

Alshogran OY, Ocque AJ, Leblond FA, Pichette V, Nolin TD.

J Chromatogr Sci. 2016 Apr;54(4):554-60. doi: 10.1093/chromsci/bmv186. Epub 2015 Dec 11.


Randomized Clinical Trial of Sodium Polystyrene Sulfonate for the Treatment of Mild Hyperkalemia in CKD.

Lepage L, Dufour AC, Doiron J, Handfield K, Desforges K, Bell R, Vallée M, Savoie M, Perreault S, Laurin LP, Pichette V, Lafrance JP.

Clin J Am Soc Nephrol. 2015 Dec 7;10(12):2136-42. doi: 10.2215/CJN.03640415. Epub 2015 Nov 17.


In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions.

Boily MO, Chauret N, Laterreur J, Leblond FA, Boudreau C, Duquet MC, Lévesque JF, Ste-Marie L, Pichette V.

Drug Metab Dispos. 2015 Dec;43(12):1960-5. doi: 10.1124/dmd.115.066357. Epub 2015 Oct 5.


Acute Kidney Injury and Renal Recovery with the Use of Aminoglycosides: A Large Retrospective Study.

Paquette F, Bernier-Jean A, Brunette V, Ammann H, Lavergne V, Pichette V, Troyanov S, Bouchard J.

Nephron. 2015;131(3):153-60. doi: 10.1159/000440867. Epub 2015 Sep 22.


Efficacy of calcitriol compared to alfacalcidol for the treatment of secondary hyperparathyroidism in peritoneal dialysis patients.

Bezzaoucha S, Lafrance JP, Ouimet D, Pichette V, Bell R, Lamarche C, Vallée M.

Int J Clin Pharmacol Ther. 2015 Oct;53(10):895-6. doi: 10.5414/CP202430. No abstract available.


Pharmacokinetics of an extended 4-hour infusion of piperacillin-tazobactam in critically ill patients undergoing continuous renal replacement therapy.

Awissi DK, Beauchamp A, Hébert E, Lavigne V, Munoz DL, Lebrun G, Savoie M, Fagnan M, Amyot J, Tétreault N, Robitaille R, Varin F, Lavallée C, Pichette V, Leblanc M.

Pharmacotherapy. 2015 Jun;35(6):600-7. doi: 10.1002/phar.1604.


The effect of lanthanum carbonate on metabolic acidosis in patients with chronic kidney disease stage IV, V and V-D.

Beaubien-Souligny W, Bezzaoucha S, Pichette V, Lafrance JP, Bell R, Lamarche C, Ouimet D, Vallee M.

Int Urol Nephrol. 2015 Jul;47(7):1165-71. doi: 10.1007/s11255-015-1003-3. Epub 2015 May 17.


[Drug pharmacokinetics in renal failure: What's new?].

Naud J, Dumayne C, Nolin TD, Leblond FA, Pichette V.

Nephrol Ther. 2015 Jun;11(3):144-51. doi: 10.1016/j.nephro.2014.12.006. Epub 2015 Apr 7. Review. French.


Effect of experimental kidney disease on the functional expression of hepatic reductases.

Alshogran OY, Naud J, Ocque AJ, Leblond FA, Pichette V, Nolin TD.

Drug Metab Dispos. 2015 Jan;43(1):100-6. doi: 10.1124/dmd.114.061150. Epub 2014 Oct 20.


Effect of parathyroidectomy on vitamin D levels.

Lamarche C, Leblond F, Ouimet D, Pichette V.

World J Surg. 2015 May;39(5):1333-4. doi: 10.1007/s00268-014-2836-0. No abstract available.


Comparison of oral and intravenous alfacalcidol in chronic hemodialysis patients.

Lessard M, Ouimet D, Leblanc M, Nadeau-Fredette AC, Bell R, Lafrance JP, Pichette V, Vallée M.

BMC Nephrol. 2014 Feb 4;15:27. doi: 10.1186/1471-2369-15-27.


Pharmacokinetic characterization of baclofen in patients with chronic kidney disease: dose adjustment recommendations.

Vlavonou R, Perreault MM, Barrière O, Shink E, Tremblay PO, Larouche R, Pichette V, Tanguay M.

J Clin Pharmacol. 2014 May;54(5):584-92. doi: 10.1002/jcph.247. Epub 2014 Jan 10.


Hemodialysis effects on phenytoin pharmacokinetics.

Bezzaoucha S, Merghoub A, Lamarche C, Pichette V, Lafrance JP, Laurin LP, Vallée M, Robitaille R, Leblanc M, Bell R.

Eur J Clin Pharmacol. 2014 Apr;70(4):499-500. doi: 10.1007/s00228-013-1628-z. Epub 2014 Jan 4. No abstract available.


Determination of warfarin alcohols by ultra-high performance liquid chromatography-tandem mass spectrometry: application to in vitro enzyme kinetic studies.

Alshogran OY, Ocque AJ, Zhao J, Day BW, Leblond FA, Pichette V, Nolin TD.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jan 1;944:63-8. doi: 10.1016/j.jchromb.2013.11.014. Epub 2013 Nov 14.


The role of sevelamer carbonate in increasing serum bicarbonate in hyperphosphatemic predialysis patients who have metabolic acidosis.

Bezzaoucha S, Pichette V, Lafrance JP, Bell R, Laurin LP, Vallée M.

Int J Clin Pharmacol Ther. 2013 Dec;51(12):989-90. doi: 10.5414/CP201941. No abstract available.


Clinical value of inflammatory urinary biomarkers in overt diabetic nephropathy: a prospective study.

Verhave JC, Bouchard J, Goupil R, Pichette V, Brachemi S, Madore F, Troyanov S.

Diabetes Res Clin Pract. 2013 Sep;101(3):333-40. doi: 10.1016/j.diabres.2013.07.006. Epub 2013 Jul 20.


Bicarbonates for the prevention of postoperative renal failure in endovascular aortic aneurysm repair: a randomized pilot trial.

Brulotte V, Leblond FA, Elkouri S, Thérasse E, Pichette V, Beaulieu P.

Anesthesiol Res Pract. 2013;2013:467326. doi: 10.1155/2013/467326. Epub 2013 Jun 12.


Effect of cinacalcet availability and formulary listing on parathyroidectomy rate trends.

Lafrance JP, Cardinal H, Leblanc M, Madore F, Pichette V, Roy L, Le Lorier J.

BMC Nephrol. 2013 May 3;14:100. doi: 10.1186/1471-2369-14-100.


Magnitude of discordance between registry data and death certificate when evaluating leading causes of death in dialysis patients.

Lafrance JP, Rahme E, Iqbal S, Leblanc M, Pichette V, Elftouh N, Vallée M.

BMC Med Res Methodol. 2013 Mar 27;13:51. doi: 10.1186/1471-2288-13-51.


Transplantation of mesenchymal stem cells promotes tissue regeneration in a glaucoma model through laser-induced paracrine factor secretion and progenitor cell recruitment.

Manuguerra-Gagné R, Boulos PR, Ammar A, Leblond FA, Krosl G, Pichette V, Lesk MR, Roy DC.

Stem Cells. 2013 Jun;31(6):1136-48. doi: 10.1002/stem.1364.


Restoration of renal function by a novel prostaglandin EP4 receptor-derived peptide in models of acute renal failure.

Leduc M, Hou X, Hamel D, Sanchez M, Quiniou C, Honoré JC, Roy O, Madaan A, Lubell W, Varma DR, Mancini J, Duhamel F, Peri KG, Pichette V, Heveker N, Chemtob S.

Am J Physiol Regul Integr Comp Physiol. 2013 Jan 1;304(1):R10-22. doi: 10.1152/ajpregu.00138.2012. Epub 2012 Nov 14.


Influence of SLCO1B3 genetic variations on tacrolimus pharmacokinetics in renal transplant recipients.

Boivin AA, Cardinal H, Barama A, Naud J, Pichette V, Hébert MJ, Roger M.

Drug Metab Pharmacokinet. 2013;28(3):274-7. Epub 2012 Nov 13.


Calcidiol deficiency in CKD patients: the role of reduced liver synthesis.

Pichette V, Ouimet D, Leblond FA.

Am J Kidney Dis. 2012 Dec;60(6):1049; author reply 1049. doi: 10.1053/j.ajkd.2012.07.027. No abstract available.


A case of an aortic dissection in a young adult: a refresher of the literature of this "great masquerader".

Pineault J, Ouimet D, Pichette V, Vallée M.

Int J Gen Med. 2011;4:889-93. doi: 10.2147/IJGM.S22906. Epub 2011 Dec 22.


Current understanding of drug disposition in kidney disease.

Naud J, Nolin TD, Leblond FA, Pichette V.

J Clin Pharmacol. 2012 Jan;52(1 Suppl):10S-22S. doi: 10.1177/0091270011413588. Review.


Effects of chronic renal failure on brain drug transporters in rats.

Naud J, Laurin LP, Michaud J, Beauchemin S, Leblond FA, Pichette V.

Drug Metab Dispos. 2012 Jan;40(1):39-46. doi: 10.1124/dmd.111.041145. Epub 2011 Oct 3.


Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats.

Naud J, Michaud J, Beauchemin S, Hébert MJ, Roger M, Lefrancois S, Leblond FA, Pichette V.

Drug Metab Dispos. 2011 Aug;39(8):1363-9. doi: 10.1124/dmd.111.039115. Epub 2011 Apr 27.


Rationale for heating oxaliplatin for the intraperitoneal treatment of peritoneal carcinomatosis: a study of the effect of heat on intraperitoneal oxaliplatin using a murine model.

Piché N, Leblond FA, Sidéris L, Pichette V, Drolet P, Fortier LP, Mitchell A, Dubé P.

Ann Surg. 2011 Jul;254(1):138-44. doi: 10.1097/SLA.0b013e3182193143.


Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.

Boivin AA, Cardinal H, Barama A, Pichette V, Hébert MJ, Roger M.

Drug Metab Pharmacokinet. 2010;25(5):508-15. Epub 2010 Sep 22.


Reduced hepatic synthesis of calcidiol in uremia.

Michaud J, Naud J, Ouimet D, Demers C, Petit JL, Leblond FA, Bonnardeaux A, Gascon-Barré M, Pichette V.

J Am Soc Nephrol. 2010 Sep;21(9):1488-97. doi: 10.1681/ASN.2009080815. Epub 2010 Jul 1.


Urinary monocyte chemotactic protein 1: marker of renal function decline in diabetic and nondiabetic proteinuric renal disease.

Camilla R, Brachemi S, Pichette V, Cartier P, Laforest-Renald A, MacRae T, Madore F, Troyanov S.

J Nephrol. 2011 Jan-Feb;24(1):60-7.


Down-regulation of liver drug-metabolizing enzymes in a murine model of chronic renal failure.

Dani M, Boisvert C, Michaud J, Naud J, Lefrançois S, Leblond FA, Pichette V.

Drug Metab Dispos. 2010 Mar;38(3):357-60. doi: 10.1124/dmd.109.029991. Epub 2009 Dec 9.


ESRD impairs nonrenal clearance of fexofenadine but not midazolam.

Nolin TD, Frye RF, Le P, Sadr H, Naud J, Leblond FA, Pichette V, Himmelfarb J.

J Am Soc Nephrol. 2009 Oct;20(10):2269-76. doi: 10.1681/ASN.2009010082. Epub 2009 Aug 20.

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