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Items: 1 to 50 of 106

1.

Foxp3 Post-translational Modifications and Treg Suppressive Activity.

Deng G, Song X, Fujimoto S, Piccirillo CA, Nagai Y, Greene MI.

Front Immunol. 2019 Oct 18;10:2486. doi: 10.3389/fimmu.2019.02486. eCollection 2019. Review.

2.

Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation.

Esfahani K, Al-Aubodah TA, Thebault P, Lapointe R, Hudson M, Johnson NA, Baran D, Bhulaiga N, Takano T, Cailhier JF, Piccirillo CA, Miller WH.

Nat Commun. 2019 Oct 17;10(1):4712. doi: 10.1038/s41467-019-12628-1.

3.

Rebalancing Immune Homeostasis to Treat Autoimmune Diseases.

Horwitz DA, Fahmy TM, Piccirillo CA, La Cava A.

Trends Immunol. 2019 Oct;40(10):888-908. doi: 10.1016/j.it.2019.08.003. Epub 2019 Oct 7. Review.

PMID:
31601519
4.

The Deubiquitinating Enzyme Ubiquitin-Specific Peptidase 11 Potentiates TGF-β Signaling in CD4+ T Cells to Facilitate Foxp3+ Regulatory T and TH17 Cell Differentiation.

Istomine R, Alvarez F, Almadani Y, Philip A, Piccirillo CA.

J Immunol. 2019 Nov 1;203(9):2388-2400. doi: 10.4049/jimmunol.1801689. Epub 2019 Sep 25.

PMID:
31554694
5.

PD-1/PD-L1 Immune-Checkpoint Inhibition with Radiation in Bladder Cancer: In Situ and Abscopal Effects.

Rompré-Brodeur A, Shinde-Jadhav S, Ayoub M, Piccirillo CA, Seuntjens J, Brimo F, Mansure JJ, Kassouf W.

Mol Cancer Ther. 2019 Sep 18. pii: molcanther.0986.2018. doi: 10.1158/1535-7163.MCT-18-0986. [Epub ahead of print]

PMID:
31534011
6.

Signaling Through gp130 Compromises Suppressive Function in Human FOXP3+ Regulatory T Cells.

Bin Dhuban K, Bartolucci S, d'Hennezel E, Piccirillo CA.

Front Immunol. 2019 Jul 18;10:1532. doi: 10.3389/fimmu.2019.01532. eCollection 2019.

7.

Regulatory T cells: exploring mechanisms for future therapies.

Piccirillo CA.

Clin Exp Immunol. 2019 Jul;197(1):11-13. doi: 10.1111/cei.13338. No abstract available.

PMID:
31177531
8.

The immune mediated role of extracellular HMGB1 in a heterotopic model of bladder cancer radioresistance.

Ayoub M, Shinde-Jadhav S, Mansure JJ, Alvarez F, Connell T, Seuntjens J, Piccirillo CA, Kassouf W.

Sci Rep. 2019 Apr 23;9(1):6348. doi: 10.1038/s41598-019-42864-w.

9.

Pleiotropic Effects of IL-33 on CD4+ T Cell Differentiation and Effector Functions.

Alvarez F, Fritz JH, Piccirillo CA.

Front Immunol. 2019 Mar 20;10:522. doi: 10.3389/fimmu.2019.00522. eCollection 2019.

10.

Plasmodium chabaudi AS Infection Induces CD4+ Th1 Cells and Foxp3+T-bet+ Regulatory T Cells That Express CXCR3 and Migrate to CXCR3 Ligands.

Berretta F, Piccirillo CA, Stevenson MM.

Front Immunol. 2019 Mar 11;10:425. doi: 10.3389/fimmu.2019.00425. eCollection 2019.

11.

The alarmins IL-1 and IL-33 differentially regulate the functional specialisation of Foxp3+ regulatory T cells during mucosal inflammation.

Alvarez F, Istomine R, Shourian M, Pavey N, Al-Aubodah TA, Qureshi S, Fritz JH, Piccirillo CA.

Mucosal Immunol. 2019 May;12(3):746-760. doi: 10.1038/s41385-019-0153-5. Epub 2019 Mar 11.

PMID:
30872761
12.

Mechanisms of human FoxP3+ Treg cell development and function in health and disease.

Attias M, Al-Aubodah T, Piccirillo CA.

Clin Exp Immunol. 2019 Jul;197(1):36-51. doi: 10.1111/cei.13290. Epub 2019 Apr 1. Review.

13.

CD4+ Regulatory T Lymphocytes Prevent Impaired Cerebral Blood Flow in Angiotensin II-Induced Hypertension.

Iulita MF, Duchemin S, Vallerand D, Barhoumi T, Alvarez F, Istomine R, Laurent C, Youwakim J, Paradis P, Arbour N, Piccirillo CA, Schiffrin EL, Girouard H.

J Am Heart Assoc. 2019 Jan 8;8(1):e009372. doi: 10.1161/JAHA.118.009372.

14.

The Microbiota and Immune System Crosstalk in Health and Disease.

Cianci R, Pagliari D, Piccirillo CA, Fritz JH, Gambassi G.

Mediators Inflamm. 2018 Apr 22;2018:2912539. doi: 10.1155/2018/2912539. eCollection 2018. No abstract available.

15.

Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.

Robichaud N, Hsu BE, Istomine R, Alvarez F, Blagih J, Ma EH, Morales SV, Dai DL, Li G, Souleimanova M, Guo Q, Del Rincon SV, Miller WH Jr, Ramón Y Cajal S, Park M, Jones RG, Piccirillo CA, Siegel PM, Sonenberg N.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2202-E2209. doi: 10.1073/pnas.1717439115. Epub 2018 Feb 20.

16.

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P.

Front Immunol. 2018 Jan 15;8:1844. doi: 10.3389/fimmu.2017.01844. eCollection 2017.

17.

The Intricate Link among Gut "Immunological Niche," Microbiota, and Xenobiotics in Intestinal Pathology.

Pagliari D, Gambassi G, Piccirillo CA, Cianci R.

Mediators Inflamm. 2017;2017:8390595. doi: 10.1155/2017/8390595. Epub 2017 Oct 8. Review.

18.

KLRG1 expression identifies short-lived Foxp3+ Treg effector cells with functional plasticity in islets of NOD mice.

Kornete M, Mason E, Istomine R, Piccirillo CA.

Autoimmunity. 2017 Sep;50(6):354-362. doi: 10.1080/08916934.2017.1364368. Epub 2017 Aug 29.

PMID:
28850267
19.

Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions.

Bin Dhuban K, d'Hennezel E, Nagai Y, Xiao Y, Shao S, Istomine R, Alvarez F, Ben-Shoshan M, Ochs H, Mazer B, Li B, Sekine C, Berezov A, Hancock W, Torgerson TR, Greene MI, Piccirillo CA.

Sci Immunol. 2017 Jun 16;2(12). pii: eaai9297. doi: 10.1126/sciimmunol.aai9297.

PMID:
28783662
20.

The common, autoimmunity-predisposing 620Arg > Trp variant of PTPN22 modulates macrophage function and morphology.

Li M, Beauchemin H, Popovic N, Peterson A, d'Hennezel E, Piccirillo CA, Sun C, Polychronakos C.

J Autoimmun. 2017 May;79:74-83. doi: 10.1016/j.jaut.2017.01.009. Epub 2017 Feb 22.

PMID:
28237724
21.

Peripherally Generated Foxp3+ Regulatory T Cells Mediate the Immunomodulatory Effects of IVIg in Allergic Airways Disease.

Massoud AH, Kaufman GN, Xue D, Béland M, Dembele M, Piccirillo CA, Mourad W, Mazer BD.

J Immunol. 2017 Apr 1;198(7):2760-2771. doi: 10.4049/jimmunol.1502361. Epub 2017 Feb 20.

22.

A Regulatory T-Cell Gene Signature Is a Specific and Sensitive Biomarker to Identify Children With New-Onset Type 1 Diabetes.

Pesenacker AM, Wang AY, Singh A, Gillies J, Kim Y, Piccirillo CA, Nguyen D, Haining WN, Tebbutt SJ, Panagiotopoulos C, Levings MK.

Diabetes. 2016 Apr;65(4):1031-9. doi: 10.2337/db15-0572. Epub 2016 Jan 19.

23.

Posttranscriptional and Translational Control of Gene Regulation in CD4+ T Cell Subsets.

Istomine R, Pavey N, Piccirillo CA.

J Immunol. 2016 Jan 15;196(2):533-40. doi: 10.4049/jimmunol.1501337. Review.

24.

The immunological and genetic basis of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.

Bin Dhuban K, Piccirillo CA.

Curr Opin Allergy Clin Immunol. 2015 Dec;15(6):525-32. doi: 10.1097/ACI.0000000000000214. Review.

PMID:
26485097
25.

Induction of Regulatory T Cells by Intravenous Immunoglobulin: A Bridge between Adaptive and Innate Immunity.

Kaufman GN, Massoud AH, Dembele M, Yona M, Piccirillo CA, Mazer BD.

Front Immunol. 2015 Sep 11;6:469. doi: 10.3389/fimmu.2015.00469. eCollection 2015. Review.

26.

The Interactions between Innate Immunity and Microbiota in Gastrointestinal Diseases.

Pagliari D, Piccirillo CA, Larbi A, Cianci R.

J Immunol Res. 2015;2015:898297. doi: 10.1155/2015/898297. Epub 2015 May 20. No abstract available.

27.

Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice.

Kornete M, Mason ES, Girouard J, Lafferty EI, Qureshi S, Piccirillo CA.

PLoS One. 2015 May 6;10(5):e0126311. doi: 10.1371/journal.pone.0126311. eCollection 2015.

28.

Coexpression of TIGIT and FCRL3 identifies Helios+ human memory regulatory T cells.

Bin Dhuban K, d'Hennezel E, Nashi E, Bar-Or A, Rieder S, Shevach EM, Nagata S, Piccirillo CA.

J Immunol. 2015 Apr 15;194(8):3687-96. doi: 10.4049/jimmunol.1401803. Epub 2015 Mar 11.

29.

The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.

Blagih J, Coulombe F, Vincent EE, Dupuy F, Galicia-Vázquez G, Yurchenko E, Raissi TC, van der Windt GJ, Viollet B, Pearce EL, Pelletier J, Piccirillo CA, Krawczyk CM, Divangahi M, Jones RG.

Immunity. 2015 Jan 20;42(1):41-54. doi: 10.1016/j.immuni.2014.12.030. Epub 2015 Jan 2.

30.

Reply: To PMID 24210883.

Massoud AH, Kaufman GN, Piccirillo CA, Mazer BD.

J Allergy Clin Immunol. 2014 Dec;134(6):1469-1470. doi: 10.1016/j.jaci.2014.08.050. Epub 2014 Oct 28. No abstract available.

PMID:
25441302
31.

An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.

Lafferty EI, Flaczyk A, Angers I, Homer R, d'Hennezel E, Malo D, Piccirillo CA, Vidal SM, Qureshi ST.

Genes Immun. 2014 Jul-Aug;15(5):320-32. doi: 10.1038/gene.2014.22. Epub 2014 May 22.

32.

Translational control of immune responses: from transcripts to translatomes.

Piccirillo CA, Bjur E, Topisirovic I, Sonenberg N, Larsson O.

Nat Immunol. 2014 Jun;15(6):503-11. doi: 10.1038/ni.2891. Review.

PMID:
24840981
33.

Functional dynamics of Foxp3⁺ regulatory T cells in mice and humans.

Bin Dhuban K, Kornete M, S Mason E, Piccirillo CA.

Immunol Rev. 2014 May;259(1):140-58. doi: 10.1111/imr.12168. Review.

PMID:
24712464
34.

Functional evaluation of the role of C-type lectin domain family 16A at the chromosome 16p13 locus.

Zouk H, D'Hennezel E, Du X, Ounissi-Benkalha H, Piccirillo CA, Polychronakos C.

Clin Exp Immunol. 2014 Mar;175(3):485-97. doi: 10.1111/cei.12240.

35.

Dendritic cell immunoreceptor: a novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells.

Massoud AH, Yona M, Xue D, Chouiali F, Alturaihi H, Ablona A, Mourad W, Piccirillo CA, Mazer BD.

J Allergy Clin Immunol. 2014 Mar;133(3):853-63.e5. doi: 10.1016/j.jaci.2013.09.029. Epub 2013 Nov 8.

PMID:
24210883
36.

Altered T helper 17 responses in children with food allergy.

Dhuban KB, d'Hennezel E, Ben-Shoshan M, McCusker C, Clarke A, Fiset P, Mazer B, Piccirillo CA.

Int Arch Allergy Immunol. 2013;162(4):318-22. doi: 10.1159/000354028. Epub 2013 Oct 25.

37.

Environmental sensing and regulation of gene expression in CD4+ T cell subsets.

Piccirillo CA.

Curr Opin Immunol. 2013 Oct;25(5):564-70. doi: 10.1016/j.coi.2013.09.006. Epub 2013 Oct 17. Review.

PMID:
24140232
38.

Developmental plasticity of murine and human Foxp3(+) regulatory T cells.

Liston A, Piccirillo CA.

Adv Immunol. 2013;119:85-106. doi: 10.1016/B978-0-12-407707-2.00003-5.

PMID:
23886065
39.

Immune Regulation in T1D and T2D: Prospective Role of Foxp3+ Treg Cells in Disease Pathogenesis and Treatment.

Kornete M, Mason ES, Piccirillo CA.

Front Endocrinol (Lausanne). 2013 Jun 25;4:76. doi: 10.3389/fendo.2013.00076. eCollection 2013.

40.

Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice.

Li J, Heinrichs J, Leconte J, Haarberg K, Semple K, Liu C, Gigoux M, Kornete M, Piccirillo CA, Suh WK, Yu XZ.

J Immunol. 2013 Jul 1;191(1):200-7. doi: 10.4049/jimmunol.1203485. Epub 2013 May 31.

41.

Distinct translational control in CD4+ T cell subsets.

Bjur E, Larsson O, Yurchenko E, Zheng L, Gandin V, Topisirovic I, Li S, Wagner CR, Sonenberg N, Piccirillo CA.

PLoS Genet. 2013 May;9(5):e1003494. doi: 10.1371/journal.pgen.1003494. Epub 2013 May 2.

42.

Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice.

Kornete M, Beauchemin H, Polychronakos C, Piccirillo CA.

Autoimmunity. 2013 Jun;46(4):259-68. doi: 10.3109/08916934.2012.752462. Epub 2013 Feb 4.

PMID:
23256897
43.

Functional stability of Foxp3+ regulatory T cells.

da Silva Martins M, Piccirillo CA.

Trends Mol Med. 2012 Aug;18(8):454-62. doi: 10.1016/j.molmed.2012.06.001. Epub 2012 Jul 6. Review.

PMID:
22771168
44.

Functional crosstalk between dendritic cells and Foxp3(+) regulatory T cells in the maintenance of immune tolerance.

Kornete M, Piccirillo CA.

Front Immunol. 2012 Jun 22;3:165. doi: 10.3389/fimmu.2012.00165. eCollection 2012.

45.

Mesenchymal stromal cells improve salivary function and reduce lymphocytic infiltrates in mice with Sjögren's-like disease.

Khalili S, Liu Y, Kornete M, Roescher N, Kodama S, Peterson A, Piccirillo CA, Tran SD.

PLoS One. 2012;7(6):e38615. doi: 10.1371/journal.pone.0038615. Epub 2012 Jun 7.

46.

The immunogenetics of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome.

d'Hennezel E, Bin Dhuban K, Torgerson T, Piccirillo CA.

J Med Genet. 2012 May;49(5):291-302. doi: 10.1136/jmedgenet-2012-100759. Review. Erratum in: J Med Genet. 2012 Dec;49(12):784. Piccirillo, Ciriaco [corrected to Piccirillo, Ciriaco A].

PMID:
22581967
47.

Intravenous immunoglobulin attenuates airway inflammation through induction of forkhead box protein 3-positive regulatory T cells.

Massoud AH, Guay J, Shalaby KH, Bjur E, Ablona A, Chan D, Nouhi Y, McCusker CT, Mourad MW, Piccirillo CA, Mazer BD.

J Allergy Clin Immunol. 2012 Jun;129(6):1656-65.e3. doi: 10.1016/j.jaci.2012.02.050. Epub 2012 May 5.

PMID:
22564681
48.

Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo.

Yurchenko E, Shio MT, Huang TC, Da Silva Martins M, Szyf M, Levings MK, Olivier M, Piccirillo CA.

PLoS One. 2012;7(4):e35572. doi: 10.1371/journal.pone.0035572. Epub 2012 Apr 24.

49.

Functional plasticity in human FOXP3(+) regulatory T cells: implications for cell-based immunotherapy.

d'Hennezel E, Piccirillo CA.

Hum Vaccin Immunother. 2012 Jul;8(7):1001-5. doi: 10.4161/hv.20203. Epub 2012 Jul 1. Review.

PMID:
22484225
50.

ICOS-dependent homeostasis and function of Foxp3+ regulatory T cells in islets of nonobese diabetic mice.

Kornete M, Sgouroudis E, Piccirillo CA.

J Immunol. 2012 Feb 1;188(3):1064-74. doi: 10.4049/jimmunol.1101303. Epub 2012 Jan 6.

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