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Items: 1 to 50 of 211

1.

Evaluation of the Phosphoproteome of Mouse Alpha 4/Beta 2-Containing Nicotinic Acetylcholine Receptors In Vitro and In Vivo.

Miller MB, Wilson RS, Lam TT, Nairn AC, Picciotto MR.

Proteomes. 2018 Oct 15;6(4). pii: E42. doi: 10.3390/proteomes6040042.

2.

The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development.

Tebbenkamp ATN, Varela L, Choi J, Paredes MI, Giani AM, Song JE, Sestan-Pesa M, Franjic D, Sousa AMM, Liu ZW, Li M, Bichsel C, Koch M, Szigeti-Buck K, Liu F, Li Z, Kawasawa YI, Paspalas CD, Mineur YS, Prontera P, Merla G, Picciotto MR, Arnsten AFT, Horvath TL, Sestan N.

Cell. 2018 Nov 1;175(4):1088-1104.e23. doi: 10.1016/j.cell.2018.09.014.

PMID:
30318146
3.

Science is a Marathon Not a Sprint: Creating a Positive Culture for Early Career Researchers.

Picciotto MR, Munafò MR.

Nicotine Tob Res. 2018 Aug 14;20(9):1037. doi: 10.1093/ntr/nty113. No abstract available.

PMID:
29868800
4.

Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons.

Li D, Musante V, Zhou W, Picciotto MR, Nairn AC.

J Biol Chem. 2018 Jul 13;293(28):11179-11194. doi: 10.1074/jbc.RA117.001519. Epub 2018 May 25.

PMID:
29802198
5.

Molecular and cellular characterization of nicotinic acetylcholine receptor subtypes in the arcuate nucleus of the mouse hypothalamus.

Calarco CA, Li Z, Taylor SR, Lee S, Zhou W, Friedman JM, Mineur YS, Gotti C, Picciotto MR.

Eur J Neurosci. 2018 May 23. doi: 10.1111/ejn.13966. [Epub ahead of print]

PMID:
29791746
6.

An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder.

Lewis AS, van Schalkwyk GI, Lopez MO, Volkmar FR, Picciotto MR, Sukhodolsky DG.

J Autism Dev Disord. 2018 Aug;48(8):2748-2757. doi: 10.1007/s10803-018-3536-7.

PMID:
29536216
7.

Interaction between noradrenergic and cholinergic signaling in amygdala regulates anxiety- and depression-related behaviors in mice.

Mineur YS, Cahuzac EL, Mose TN, Bentham MP, Plantenga ME, Thompson DC, Picciotto MR.

Neuropsychopharmacology. 2018 Sep;43(10):2118-2125. doi: 10.1038/s41386-018-0024-x. Epub 2018 Feb 22.

PMID:
29472646
8.

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.

Lewis AS, Pittenger ST, Mineur YS, Stout D, Smith PH, Picciotto MR.

Neuropsychopharmacology. 2018 May;43(6):1267-1275. doi: 10.1038/npp.2017.276. Epub 2017 Nov 7.

PMID:
29114104
9.

Effects of a nicotinic agonist on the Brief Psychiatric Rating Scale five-factor subscale model in schizophrenia.

Lewis AS, Olincy A, Buchanan RW, Kem WR, Picciotto MR, Freedman R.

Schizophr Res. 2018 May;195:568-569. doi: 10.1016/j.schres.2017.10.016. Epub 2017 Oct 16. No abstract available.

PMID:
29050790
10.

The Effect of Treatment with Guanfacine, an Alpha2 Adrenergic Agonist, on Dopaminergic Tone in Tobacco Smokers: An [11C]FLB457 PET Study.

Sandiego CM, Matuskey D, Lavery M, McGovern E, Huang Y, Nabulsi N, Ropchan J, Picciotto MR, Morris ED, McKee SA, Cosgrove KP.

Neuropsychopharmacology. 2018 Apr;43(5):1052-1058. doi: 10.1038/npp.2017.223. Epub 2017 Sep 25.

PMID:
28944773
11.

Menthol disrupts nicotine's psychostimulant properties in an age and sex-dependent manner in C57BL/6J mice.

Fait BW, Thompson DC, Mose TN, Jatlow P, Jordt SE, Picciotto MR, Mineur YS.

Behav Brain Res. 2017 Sep 15;334:72-77. doi: 10.1016/j.bbr.2017.07.027. Epub 2017 Jul 22.

12.

Maternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators.

Jung Y, Lee AM, McKee SA, Picciotto MR.

Sci Rep. 2017 Jun 28;7(1):4315. doi: 10.1038/s41598-017-04413-1.

13.

Access to nicotine in drinking water reduces weight gain without changing caloric intake on high fat diet in male C57BL/6J mice.

Calarco CA, Lee S, Picciotto MR.

Neuropharmacology. 2017 Sep 1;123:210-220. doi: 10.1016/j.neuropharm.2017.06.012. Epub 2017 Jun 13.

14.

Effect of doxazosin on stress reactivity and the ability to resist smoking.

Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA.

J Psychopharmacol. 2017 Jul;31(7):830-840. doi: 10.1177/0269881117699603. Epub 2017 Apr 25.

15.

Effects of varenicline on alcohol self-administration and craving in drinkers with depressive symptoms.

Roberts W, Verplaetse TL, Moore K, Oberleitner L, Picciotto MR, McKee SA.

J Psychopharmacol. 2017 Jul;31(7):906-914. doi: 10.1177/0269881117699618. Epub 2017 Mar 29.

16.

Hippocampal α7 nicotinic ACh receptors contribute to modulation of depression-like behaviour in C57BL/6J mice.

Mineur YS, Mose TN, Blakeman S, Picciotto MR.

Br J Pharmacol. 2018 Jun;175(11):1903-1914. doi: 10.1111/bph.13769. Epub 2017 Apr 8.

PMID:
28264149
17.

Editorial: Progressions.

Picciotto MR.

J Neurosci. 2017 Feb 1;37(5):1055. doi: 10.1523/JNEUROSCI.3837-16.2016. No abstract available. Erratum in: J Neurosci. 2017 Apr 26;37(17 ):4645.

18.

Menthol decreases oral nicotine aversion in C57BL/6 mice through a TRPM8-dependent mechanism.

Fan L, Balakrishna S, Jabba SV, Bonner PE, Taylor SR, Picciotto MR, Jordt SE.

Tob Control. 2016 Nov;25(Suppl 2):ii50-ii54. doi: 10.1136/tobaccocontrol-2016-053209. Epub 2016 Oct 3.

19.

CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory.

Park J, Chávez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S.

Neuron. 2016 Oct 5;92(1):75-83. doi: 10.1016/j.neuron.2016.09.002. Epub 2016 Sep 22.

20.

CHRNA4 and ANKK1 Polymorphisms Influence Smoking-Induced Nicotinic Acetylcholine Receptor Upregulation.

Esterlis I, Hillmer AT, Bois F, Pittman B, McGovern E, O'Malley SS, Picciotto MR, Yang BZ, Gelernter J, Cosgrove KP.

Nicotine Tob Res. 2016 Sep;18(9):1845-52. doi: 10.1093/ntr/ntw081. Epub 2016 Mar 31.

21.

Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex.

McClure-Begley TD, Esterlis I, Stone KL, Lam TT, Grady SR, Colangelo CM, Lindstrom JM, Marks MJ, Picciotto MR.

eNeuro. 2016 Aug 16;3(4). pii: ENEURO.0166-16.2016. doi: 10.1523/ENEURO.0166-16.2016. eCollection 2016 Jul-Aug.

22.

GABA interneurons mediate the rapid antidepressant-like effects of scopolamine.

Wohleb ES, Wu M, Gerhard DM, Taylor SR, Picciotto MR, Alreja M, Duman RS.

J Clin Invest. 2016 Jul 1;126(7):2482-94. doi: 10.1172/JCI85033. Epub 2016 Jun 6.

23.

An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior.

Jung Y, Hsieh LS, Lee AM, Zhou Z, Coman D, Heath CJ, Hyder F, Mineur YS, Yuan Q, Goldman D, Bordey A, Picciotto MR.

Nat Neurosci. 2016 Jul;19(7):905-14. doi: 10.1038/nn.4315. Epub 2016 May 30.

24.

Association of Cigarette Smoking With Interpersonal and Self-Directed Violence in a Large Community-Based Sample.

Lewis AS, Oberleitner LM, Morgan PT, Picciotto MR, McKee SA.

Nicotine Tob Res. 2016 Jun;18(6):1456-62. doi: 10.1093/ntr/ntv287. Epub 2015 Dec 30.

25.

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons.

Engmann O, Giralt A, Gervasi N, Marion-Poll L, Gasmi L, Filhol O, Picciotto MR, Gilligan D, Greengard P, Nairn AC, Hervé D, Girault JA.

Nat Commun. 2015 Dec 7;6:10099. doi: 10.1038/ncomms10099.

26.

Multiple Nicotinic Acetylcholine Receptor Subtypes in the Mouse Amygdala Regulate Affective Behaviors and Response to Social Stress.

Mineur YS, Fote GM, Blakeman S, Cahuzac EL, Newbold SA, Picciotto MR.

Neuropsychopharmacology. 2016 May;41(6):1579-87. doi: 10.1038/npp.2015.316. Epub 2015 Oct 16.

28.

Modulation of aggressive behavior in mice by nicotinic receptor subtypes.

Lewis AS, Mineur YS, Smith PH, Cahuzac ELM, Picciotto MR.

Biochem Pharmacol. 2015 Oct 15;97(4):488-497. doi: 10.1016/j.bcp.2015.07.019. Epub 2015 Jul 23.

29.

Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice.

Mineur YS, Bentham MP, Zhou WL, Plantenga ME, McKee SA, Picciotto MR.

Psychopharmacology (Berl). 2015 Oct;232(19):3539-49. doi: 10.1007/s00213-015-4001-3. Epub 2015 Jul 7.

30.

Reduction of Aggressive Episodes After Repeated Transdermal Nicotine Administration in a Hospitalized Adolescent with Autism Spectrum Disorder.

Van Schalkwyk GI, Lewis AS, Qayyum Z, Koslosky K, Picciotto MR, Volkmar FR.

J Autism Dev Disord. 2015 Sep;45(9):3061-6. doi: 10.1007/s10803-015-2471-0.

31.

Targeting the noradrenergic system for gender-sensitive medication development for tobacco dependence.

Verplaetse TL, Weinberger AH, Smith PH, Cosgrove KP, Mineur YS, Picciotto MR, Mazure CM, McKee SA.

Nicotine Tob Res. 2015 Apr;17(4):486-95. doi: 10.1093/ntr/ntu280. Epub 2015 Mar 11. Review.

32.

Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states.

Picciotto MR, Lewis AS, van Schalkwyk GI, Mineur YS.

Neuropharmacology. 2015 Sep;96(Pt B):235-43. doi: 10.1016/j.neuropharm.2014.12.028. Epub 2015 Jan 9. Review.

33.

A translational investigation targeting stress-reactivity and prefrontal cognitive control with guanfacine for smoking cessation.

McKee SA, Potenza MN, Kober H, Sofuoglu M, Arnsten AF, Picciotto MR, Weinberger AH, Ashare R, Sinha R.

J Psychopharmacol. 2015 Mar;29(3):300-11. doi: 10.1177/0269881114562091. Epub 2014 Dec 16.

34.

Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine.

Mineur YS, Einstein EB, Bentham MP, Wigestrand MB, Blakeman S, Newbold SA, Picciotto MR.

Neuropsychopharmacology. 2015 Mar;40(4):938-46. doi: 10.1038/npp.2014.269. Epub 2014 Oct 7.

35.

Neuromodulation by acetylcholine: examples from schizophrenia and depression.

Higley MJ, Picciotto MR.

Curr Opin Neurobiol. 2014 Dec;29:88-95. doi: 10.1016/j.conb.2014.06.004. Epub 2014 Jun 28. Review.

36.

Self-administration of ethanol, cocaine, or nicotine does not decrease the soma size of ventral tegmental area dopamine neurons.

Mazei-Robison MS, Appasani R, Edwards S, Wee S, Taylor SR, Picciotto MR, Koob GF, Nestler EJ.

PLoS One. 2014 Apr 22;9(4):e95962. doi: 10.1371/journal.pone.0095962. eCollection 2014.

37.

Calcineurin downregulation in the amygdala is sufficient to induce anxiety-like and depression-like behaviors in C57BL/6J male mice.

Mineur YS, Taylor SR, Picciotto MR.

Biol Psychiatry. 2014 Jun 15;75(12):991-8. doi: 10.1016/j.biopsych.2014.03.009. Epub 2014 Mar 14.

38.

GABAergic and glutamatergic efferents of the mouse ventral tegmental area.

Taylor SR, Badurek S, Dileone RJ, Nashmi R, Minichiello L, Picciotto MR.

J Comp Neurol. 2014 Oct 1;522(14):3308-34. doi: 10.1002/cne.23603.

39.

Rare human nicotinic acetylcholine receptor α4 subunit (CHRNA4) variants affect expression and function of high-affinity nicotinic acetylcholine receptors.

McClure-Begley TD, Papke RL, Stone KL, Stokes C, Levy AD, Gelernter J, Xie P, Lindstrom J, Picciotto MR.

J Pharmacol Exp Ther. 2014 Mar;348(3):410-20. doi: 10.1124/jpet.113.209767. Epub 2014 Jan 2.

40.

In vivo evidence for β2 nicotinic acetylcholine receptor subunit upregulation in smokers as compared with nonsmokers with schizophrenia.

Esterlis I, Ranganathan M, Bois F, Pittman B, Picciotto MR, Shearer L, Anticevic A, Carlson J, Niciu MJ, Cosgrove KP, D'Souza DC.

Biol Psychiatry. 2014 Sep 15;76(6):495-502. doi: 10.1016/j.biopsych.2013.11.001. Epub 2013 Nov 13.

41.

Mediating role of stress reactivity in the effects of prenatal tobacco exposure on childhood mental health outcomes.

Park A, O'Malley SS, King SL, Picciotto MR.

Nicotine Tob Res. 2014 Feb;16(2):174-85. doi: 10.1093/ntr/ntt131. Epub 2013 Aug 29.

42.

Differential modulation of brain nicotinic acetylcholine receptor function by cytisine, varenicline, and two novel bispidine compounds: emergent properties of a hybrid molecule.

Peng C, Stokes C, Mineur YS, Picciotto MR, Tian C, Eibl C, Tomassoli I, Guendisch D, Papke RL.

J Pharmacol Exp Ther. 2013 Nov;347(2):424-37. doi: 10.1124/jpet.113.206904. Epub 2013 Aug 19.

43.

Exploring the nicotinic acetylcholine receptor-associated proteome with iTRAQ and transgenic mice.

McClure-Begley TD, Stone KL, Marks MJ, Grady SR, Colangelo CM, Lindstrom JM, Picciotto MR.

Genomics Proteomics Bioinformatics. 2013 Aug;11(4):207-18. doi: 10.1016/j.gpb.2013.05.005. Epub 2013 Jul 25.

44.

Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex.

Yang Y, Paspalas CD, Jin LE, Picciotto MR, Arnsten AF, Wang M.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12078-83. doi: 10.1073/pnas.1307849110. Epub 2013 Jul 1.

45.

Changes in the cholinergic system between bipolar depression and euthymia as measured with [123I]5IA single photon emission computed tomography.

Hannestad JO, Cosgrove KP, DellaGioia NF, Perkins E, Bois F, Bhagwagar Z, Seibyl JP, McClure-Begley TD, Picciotto MR, Esterlis I.

Biol Psychiatry. 2013 Nov 15;74(10):768-76. doi: 10.1016/j.biopsych.2013.04.004. Epub 2013 Jun 14.

46.

Morphine dependence and withdrawal induced changes in cholinergic signaling.

Neugebauer NM, Einstein EB, Lopez MB, McClure-Begley TD, Mineur YS, Picciotto MR.

Pharmacol Biochem Behav. 2013 Aug;109:77-83. doi: 10.1016/j.pbb.2013.04.015. Epub 2013 May 4.

47.

Molecules and circuits involved in nicotine addiction: The many faces of smoking.

Picciotto MR, Mineur YS.

Neuropharmacology. 2014 Jan;76 Pt B:545-53. doi: 10.1016/j.neuropharm.2013.04.028. Epub 2013 Apr 28. Review.

48.

High-affinity nicotinic acetylcholine receptor expression and trafficking abnormalities in psychiatric illness.

Lewis AS, Picciotto MR.

Psychopharmacology (Berl). 2013 Oct;229(3):477-85. doi: 10.1007/s00213-013-3126-5. Epub 2013 Apr 28. Review.

49.

An indirect resilience to addiction.

Picciotto MR.

Nat Neurosci. 2013 May;16(5):521-3. doi: 10.1038/nn.3375. No abstract available.

PMID:
23619754
50.

Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior.

Mineur YS, Obayemi A, Wigestrand MB, Fote GM, Calarco CA, Li AM, Picciotto MR.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3573-8. doi: 10.1073/pnas.1219731110. Epub 2013 Feb 11.

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