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Items: 23


The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis.

Ashraf S, Radhi M, Gowler P, Burston JJ, Gandhi RD, Thorn GJ, Piccinini AM, Walsh DA, Chapman V, de Moor CH.

Sci Rep. 2019 Mar 18;9(1):4696. doi: 10.1038/s41598-019-41140-1.


A complex interplay between the extracellular matrix and the innate immune response to microbial pathogens.

Tomlin H, Piccinini AM.

Immunology. 2018 Oct;155(2):186-201. doi: 10.1111/imm.12972. Epub 2018 Jul 5. Review.


Mesenchymal Stem Cell-Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis.

Kay AG, Long G, Tyler G, Stefan A, Broadfoot SJ, Piccinini AM, Middleton J, Kehoe O.

Sci Rep. 2017 Dec 21;7(1):18019. doi: 10.1038/s41598-017-18144-w.


Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers.

Zuliani-Alvarez L, Marzeda AM, Deligne C, Schwenzer A, McCann FE, Marsden BD, Piccinini AM, Midwood KS.

Nat Commun. 2017 Nov 17;8(1):1595. doi: 10.1038/s41467-017-01718-7.


Screening for Novel Endogenous Inflammatory Stimuli Using the Secreted Embryonic Alkaline Phosphatase NF-κB Reporter Assay.

Zuliani-Alvarez L, Piccinini AM, Midwood KS.

Bio Protoc. 2017 Apr 5;7(7). pii: e2220. doi: 10.21769/BioProtoc.2220.


Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages.

Piccinini AM, Zuliani-Alvarez L, Lim JM, Midwood KS.

Sci Signal. 2016 Aug 30;9(443):ra86. doi: 10.1126/scisignal.aaf3596.


Interfering with the CCL2-glycosaminoglycan axis as a potential approach to modulate neuroinflammation.

Gschwandtner M, Piccinini AM, Gerlza T, Adage T, Kungl AJ.

Neurosci Lett. 2016 Jul 28;626:164-73. doi: 10.1016/j.neulet.2016.05.037. Epub 2016 May 19.


Investigating the Role of Toll-Like Receptors in Models of Arthritis.

Piccinini AM, Williams L, McCann FE, Midwood KS.

Methods Mol Biol. 2016;1390:351-81. doi: 10.1007/978-1-4939-3335-8_22.


Illustrating the interplay between the extracellular matrix and microRNAs.

Piccinini AM, Midwood KS.

Int J Exp Pathol. 2014 Jun;95(3):158-80. doi: 10.1111/iep.12079. Epub 2014 Apr 25. Review.


Raised circulating tenascin-C in rheumatoid arthritis.

Page TH, Charles PJ, Piccinini AM, Nicolaidou V, Taylor PC, Midwood KS.

Arthritis Res Ther. 2012 Nov 29;14(6):R260. doi: 10.1186/ar4105.


Endogenous control of immunity against infection: tenascin-C regulates TLR4-mediated inflammation via microRNA-155.

Piccinini AM, Midwood KS.

Cell Rep. 2012 Oct 25;2(4):914-26. doi: 10.1016/j.celrep.2012.09.005. Epub 2012 Oct 19.


Structure-based design of decoy chemokines as a way to explore the pharmacological potential of glycosaminoglycans.

Adage T, Piccinini AM, Falsone A, Trinker M, Robinson J, Gesslbauer B, Kungl AJ.

Br J Pharmacol. 2012 Nov;167(6):1195-205. doi: 10.1111/j.1476-5381.2012.02089.x. Review.


Endogenous activation of adaptive immunity: tenascin-C drives interleukin-17 synthesis in murine arthritic joint disease.

Ruhmann M, Piccinini AM, Kong PL, Midwood KS.

Arthritis Rheum. 2012 Jul;64(7):2179-90. doi: 10.1002/art.34401.


A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice.

Liehn EA, Piccinini AM, Koenen RR, Soehnlein O, Adage T, Fatu R, Curaj A, Popescu A, Zernecke A, Kungl AJ, Weber C.

J Am Coll Cardiol. 2010 Nov 23;56(22):1847-57. doi: 10.1016/j.jacc.2010.04.066.


DAMPening inflammation by modulating TLR signalling.

Piccinini AM, Midwood KS.

Mediators Inflamm. 2010;2010. pii: 672395. doi: 10.1155/2010/672395. Epub 2010 Jul 13. Review.


Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation.

Goh FG, Piccinini AM, Krausgruber T, Udalova IA, Midwood KS.

J Immunol. 2010 Mar 1;184(5):2655-62. doi: 10.4049/jimmunol.0903359. Epub 2010 Jan 27.


Rationally evolving MCP-1/CCL2 into a decoy protein with potent anti-inflammatory activity in vivo.

Piccinini AM, Knebl K, Rek A, Wildner G, Diedrichs-Möhring M, Kungl AJ.

J Biol Chem. 2010 Mar 19;285(12):8782-92. doi: 10.1074/jbc.M109.043299. Epub 2010 Jan 22.


Targeting Toll-like receptors in autoimmunity.

Midwood KS, Piccinini AM, Sacre S.

Curr Drug Targets. 2009 Nov;10(11):1139-55. Review.


Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease.

Midwood K, Sacre S, Piccinini AM, Inglis J, Trebaul A, Chan E, Drexler S, Sofat N, Kashiwagi M, Orend G, Brennan F, Foxwell B.

Nat Med. 2009 Jul;15(7):774-80. doi: 10.1038/nm.1987. Epub 2009 Jun 28.


Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice.

Koenen RR, von Hundelshausen P, Nesmelova IV, Zernecke A, Liehn EA, Sarabi A, Kramp BK, Piccinini AM, Paludan SR, Kowalska MA, Kungl AJ, Hackeng TM, Mayo KH, Weber C.

Nat Med. 2009 Jan;15(1):97-103. doi: 10.1038/nm.1898. Epub 2009 Jan 4.


Developing chemokine mutants with improved proteoglycan affinity and knocked-out GPCR activity as anti-inflammatory recombinant drugs.

Potzinger H, Geretti E, Brandner B, Wabitsch V, Piccinini AM, Rek A, Kungl AJ.

Biochem Soc Trans. 2006 Jun;34(Pt 3):435-7. Review.


A proteomic snapshot of the human heat shock protein 90 interactome.

Falsone SF, Gesslbauer B, Tirk F, Piccinini AM, Kungl AJ.

FEBS Lett. 2005 Nov 21;579(28):6350-4. Epub 2005 Oct 24.


Chiral separation of natural and unnatural amino acid derivatives by micro-HPLC on a Ristocetin A stationary phase.

Piccinini AM, Schmid MG, Pajpanova T, Pancheva S, Grueva E, Gübitz G.

J Biochem Biophys Methods. 2004 Oct 29;61(1-2):11-21.


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