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Dopamine Transporter Density in de novo Parkinson's Disease Does Not Relate to the Development of Levodopa-Induced Dyskinesias.

Roussakis AA, Gennaro M, Lao-Kaim NP, Towey D, Piccini P.

J Neuroinflamm Neurodegener Dis. 2019;3(1):10000. Epub 2019 Jun 5.


Brain Imaging and Impulse Control Disorders in Parkinson's Disease.

Roussakis AA, Lao-Kaim NP, Piccini P.

Curr Neurol Neurosci Rep. 2019 Aug 8;19(9):67. doi: 10.1007/s11910-019-0980-5. Review.


Comparison of phosphodiesterase 10A and dopamine transporter levels as markers of disease burden in early Parkinson's disease.

Pagano G, Niccolini F, Wilson H, Yousaf T, Khan NL, Martino D, Plisson C, Gunn RN, Rabiner EA, Piccini P, Foltynie T, Politis M.

Mov Disord. 2019 Oct;34(10):1505-1515. doi: 10.1002/mds.27733. Epub 2019 Jun 3.


Relationship between neuromelanin and dopamine terminals within the Parkinson's nigrostriatal system.

Martín-Bastida A, Lao-Kaim NP, Roussakis AA, Searle GE, Xing Y, Gunn RN, Schwarz ST, Barker RA, Auer DP, Piccini P.

Brain. 2019 Jul 1;142(7):2023-2036. doi: 10.1093/brain/awz120.


Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System.

van Eimeren T, Antonini A, Berg D, Bohnen N, Ceravolo R, Drzezga A, Höglinger GU, Higuchi M, Lehericy S, Lewis S, Monchi O, Nestor P, Ondrus M, Pavese N, Peralta MC, Piccini P, Pineda-Pardo JÁ, Rektorová I, Rodríguez-Oroz M, Rominger A, Seppi K, Stoessl AJ, Tessitore A, Thobois S, Kaasinen V, Wenning G, Siebner HR, Strafella AP, Rowe JB.

Alzheimers Dement (Amst). 2019 Apr 2;11:301-309. doi: 10.1016/j.dadm.2019.01.011. eCollection 2019 Dec.


Role of Mycobacterium avium lysate INF-γ, IL-17, and IL-2 ELISPOT assays in diagnosing nontuberculous mycobacteria lymphadenitis in children.

Della Bella C, Venturini E, Devente S, Piccini P, Tapinassi S, Bianchi L, Grassi A, Benagiano M, Alnwaisri HFM, Montagnani C, Chiappini E, Bitter W, D'Elios MM, de Martino M, Galli L.

Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1113-1122. doi: 10.1007/s10096-019-03506-1. Epub 2019 Mar 5.


Systematic review shows that immunising internationally adopted children is a major challenge for primary health care.

Venturini E, Piccini P, Tersigni C, Chiappini E, Galli L.

Acta Paediatr. 2019 Mar;108(3):411-418. doi: 10.1111/apa.14625. Epub 2018 Nov 19. Review.


Molecular Imaging of Neuroinflammation in Idiopathic Parkinson's Disease.

Roussakis AA, Piccini P.

Int Rev Neurobiol. 2018;141:347-363. doi: 10.1016/bs.irn.2018.08.009. Epub 2018 Sep 14. Review.


Outcome of cell suspension allografts in a patient with Huntington's disease.

Maxan A, Mason S, Saint-Pierre M, Smith E, Ho A, Harrower T, Watts C, Tai Y, Pavese N, Savage JC, Tremblay MÈ, Gould P, Rosser AE, Dunnett SB, Piccini P, Barker RA, Cicchetti F.

Ann Neurol. 2018 Dec;84(6):950-956. doi: 10.1002/ana.25354. Epub 2018 Oct 25.


Diffuse hyperkeratotic lesions in a 4-year-old HIV-infected girl.

Bassi A, Piccini P, Bianchi L, Montagnani C, de Martino M, Venturini E, Galli L.

Arch Dis Child. 2019 Dec;104(12):1228. doi: 10.1136/archdischild-2018-315536. Epub 2018 Sep 4. No abstract available.


Bilateral Painful Erythematous Nodules on the Sole.

Piccini P, Venturini E, Bianchi L, Galli L, de Martino M, Bassi A.

J Pediatr. 2018 Aug;199:278. doi: 10.1016/j.jpeds.2018.03.017. Epub 2018 May 2. No abstract available.


Pallidal dopaminergic denervation and rest tremor in early Parkinson's disease: PPMI cohort analysis.

Lee JY, Lao-Kaim NP, Pasquini J, Deuschl G, Pavese N, Piccini P.

Parkinsonism Relat Disord. 2018 Jun;51:101-104. doi: 10.1016/j.parkreldis.2018.02.039. Epub 2018 Feb 24.


Latent tuberculosis in childhood: tolerability of two different therapeutic approaches.

Tersigni C, Venturini E, Cordola C, Piccini P, Bianchi L, Montagnani C, Sollai S, Chiappini E, de Martino M, Galli L.

Expert Rev Anti Infect Ther. 2018 Apr;16(4):359-365. doi: 10.1080/14787210.2018.1441025. Epub 2018 Feb 21.


Inflammatory morphea presenting as a hemifacial acquired port-wine stain.

Bassi A, Piccini P, Filippeschi C, Oranges T, Giani T, Neri I, Cimaz R, Martino M.

Arch Dis Child. 2019 Mar;104(3):296. doi: 10.1136/archdischild-2017-314721. Epub 2018 Feb 15. No abstract available.


Gender disparity in pediatrics: a review of the current literature.

Piccini P, Montagnani C, de Martino M.

Ital J Pediatr. 2018 Jan 2;44(1):1. doi: 10.1186/s13052-017-0437-x. Review.


Protocol of a single group prospective observational study on the diagnostic value of 3T susceptibility weighted MRI of nigrosome-1 in patients with parkinsonian symptoms: the N3iPD study (nigrosomal iron imaging in Parkinson's disease).

Schwarz ST, Xing Y, Naidu S, Birchall J, Skelly R, Perkins A, Evans J, Sare G, Martin-Bastida A, Bajaj N, Gowland P, Piccini P, Auer DP.

BMJ Open. 2017 Dec 14;7(12):e016904. doi: 10.1136/bmjopen-2017-016904.


Patterns of grey matter loss associated with motor subscores in early Parkinson's disease.

Li X, Xing Y, Martin-Bastida A, Piccini P, Auer DP.

Neuroimage Clin. 2017 Nov 10;17:498-504. doi: 10.1016/j.nicl.2017.11.009. eCollection 2018.


Restorative Strategies in Movement Disorders: the Contribution of Imaging.

Lao-Kaim NP, Piccini P, Tai YF.

Curr Neurol Neurosci Rep. 2017 Nov 2;17(12):98. doi: 10.1007/s11910-017-0807-1. Review.


11 C-PE2I and 18 F-Dopa PET for assessing progression rate in Parkinson's: A longitudinal study.

Li W, Lao-Kaim NP, Roussakis AA, Martín-Bastida A, Valle-Guzman N, Paul G, Loane C, Widner H, Politis M, Foltynie T, Barker RA, Piccini P.

Mov Disord. 2018 Jan;33(1):117-127. doi: 10.1002/mds.27183. Epub 2017 Oct 30.


Osteomyelitis and arthritis caused by Mycobacterium intracellulare: an underestimated diagnosis.

Piccini P, Venturini E, Romano F, Di Maurizio M, De Filippi C, Azzari C, de Martino M, Galli L.

Int J Tuberc Lung Dis. 2017 Oct 1;21(10):1184-1185. doi: 10.5588/ijtld.17.0393. No abstract available.


Chronic exposure to dopamine agonists affects the integrity of striatal D2 receptors in Parkinson's patients.

Politis M, Wilson H, Wu K, Brooks DJ, Piccini P.

Neuroimage Clin. 2017 Aug 24;16:455-460. doi: 10.1016/j.nicl.2017.08.013. eCollection 2017.


Iron metabolism and its detection through MRI in parkinsonian disorders: a systematic review.

Pietracupa S, Martin-Bastida A, Piccini P.

Neurol Sci. 2017 Dec;38(12):2095-2101. doi: 10.1007/s10072-017-3099-y. Epub 2017 Sep 2. Review.


Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson's disease.

Martin-Bastida A, Ward RJ, Newbould R, Piccini P, Sharp D, Kabba C, Patel MC, Spino M, Connelly J, Tricta F, Crichton RR, Dexter DT.

Sci Rep. 2017 May 3;7(1):1398. doi: 10.1038/s41598-017-01402-2.


Neuromelanin in parkinsonian disorders: an update.

Martin-Bastida A, Pietracupa S, Piccini P.

Int J Neurosci. 2017 Dec;127(12):1116-1123. doi: 10.1080/00207454.2017.1325883. Epub 2017 May 11. Review.


The Risk of Mycobacterium tuberculosis Transmission from Pediatric Index Cases to School Pupils.

Piccini P, Venturini E, Bianchi L, Baretti S, Filidei P, Paliaga L, Mazzoli F, Chiappini E, de Martino M, Galli L.

Pediatr Infect Dis J. 2017 May;36(5):525-528. doi: 10.1097/INF.0000000000001492.


Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers.

Strafella AP, Bohnen NI, Perlmutter JS, Eidelberg D, Pavese N, Van Eimeren T, Piccini P, Politis M, Thobois S, Ceravolo R, Higuchi M, Kaasinen V, Masellis M, Peralta MC, Obeso I, Pineda-Pardo JÁ, Cilia R, Ballanger B, Niethammer M, Stoessl JA; IPMDS-Neuroimaging Study Group.

Mov Disord. 2017 Feb;32(2):181-192. doi: 10.1002/mds.26907. Epub 2017 Feb 2. Review.


Motor associations of iron accumulation in deep grey matter nuclei in Parkinson's disease: a cross-sectional study of iron-related magnetic resonance imaging susceptibility.

Martin-Bastida A, Lao-Kaim NP, Loane C, Politis M, Roussakis AA, Valle-Guzman N, Kefalopoulou Z, Paul-Visse G, Widner H, Xing Y, Schwarz ST, Auer DP, Foltynie T, Barker RA, Piccini P.

Eur J Neurol. 2017 Feb;24(2):357-365. doi: 10.1111/ene.13208. Epub 2016 Dec 16.


Corrigendum to "Increased central microglial activation associated with peripheral cytokine levels in premanifest Huntington's disease gene carriers" [Neurobiol. Dis. 83 (2015) 115-121].

Politis M, Lahiri N, Niccolini F, Su P, Wu K, Giannetti P, Scahill RI, Turkheimer FE, Tabrizi SJ, Piccini P.

Neurobiol Dis. 2017 Feb;98:162. doi: 10.1016/j.nbd.2016.12.003. Epub 2016 Dec 8. No abstract available.


Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients.

Politis M, Sauerbier A, Loane C, Pavese N, Martin A, Corcoran B, Brooks DJ, Ray-Chaudhuri K, Piccini P.

Mov Disord. 2017 Feb;32(2):235-240. doi: 10.1002/mds.26848. Epub 2016 Nov 17.


Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease.

Rolinski M, Griffanti L, Piccini P, Roussakis AA, Szewczyk-Krolikowski K, Menke RA, Quinnell T, Zaiwalla Z, Klein JC, Mackay CE, Hu MT.

Brain. 2016 Aug;139(Pt 8):2224-34. doi: 10.1093/brain/aww124. Epub 2016 Jun 12.


Aberrant nigral diffusion in Parkinson's disease: A longitudinal diffusion tensor imaging study.

Loane C, Politis M, Kefalopoulou Z, Valle-Guzman N, Paul G, Widner H, Foltynie T, Barker RA, Piccini P.

Mov Disord. 2016 Jul;31(7):1020-6. doi: 10.1002/mds.26606. Epub 2016 Apr 22.


Serotonin-to-dopamine transporter ratios in Parkinson disease: Relevance for dyskinesias.

Roussakis AA, Politis M, Towey D, Piccini P.

Neurology. 2016 Mar 22;86(12):1152-8. doi: 10.1212/WNL.0000000000002494. Epub 2016 Feb 26.


Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis.

Colasanti A, Guo Q, Giannetti P, Wall MB, Newbould RD, Bishop C, Onega M, Nicholas R, Ciccarelli O, Muraro PA, Malik O, Owen DR, Young AH, Gunn RN, Piccini P, Matthews PM, Rabiner EA.

Biol Psychiatry. 2016 Jul 1;80(1):62-72. doi: 10.1016/j.biopsych.2015.11.022. Epub 2015 Dec 5.


PET Imaging in Huntington's Disease.

Roussakis AA, Piccini P.

J Huntingtons Dis. 2015;4(4):287-96. doi: 10.3233/JHD-150171. Review.


Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases.

Ruffmann C, Calboli FC, Bravi I, Gveric D, Curry LK, de Smith A, Pavlou S, Buxton JL, Blakemore AI, Takousis P, Molloy S, Piccini P, Dexter DT, Roncaroli F, Gentleman SM, Middleton LT.

Neuropathol Appl Neurobiol. 2016 Aug;42(5):436-50. doi: 10.1111/nan.12294. Epub 2015 Dec 2.


Psychogenic and neural visual-cue response in PD dopamine dysregulation syndrome.

Loane C, Wu K, O'Sullivan SS, Lawrence AD, Woodhead Z, Lees AJ, Piccini P, Politis M.

Parkinsonism Relat Disord. 2015 Nov;21(11):1336-41. doi: 10.1016/j.parkreldis.2015.09.042. Epub 2015 Sep 25.


Morphometric changes in the reward system of Parkinson's disease patients with impulse control disorders.

Pellicano C, Niccolini F, Wu K, O'Sullivan SS, Lawrence AD, Lees AJ, Piccini P, Politis M.

J Neurol. 2015 Dec;262(12):2653-61. doi: 10.1007/s00415-015-7892-3. Epub 2015 Sep 26.


Increased central microglial activation associated with peripheral cytokine levels in premanifest Huntington's disease gene carriers.

Politis M, Lahiri N, Niccolini F, Su P, Wu K, Giannetti P, Scahill RI, Turkheimer FE, Tabrizi SJ, Piccini P.

Neurobiol Dis. 2015 Nov;83:115-21. doi: 10.1016/j.nbd.2015.08.011. Epub 2015 Aug 18.


Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease.

Niccolini F, Foltynie T, Reis Marques T, Muhlert N, Tziortzi AC, Searle GE, Natesan S, Kapur S, Rabiner EA, Gunn RN, Piccini P, Politis M.

Brain. 2015 Oct;138(Pt 10):3003-15. doi: 10.1093/brain/awv219. Epub 2015 Jul 25.


Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease.

Niccolini F, Haider S, Reis Marques T, Muhlert N, Tziortzi AC, Searle GE, Natesan S, Piccini P, Kapur S, Rabiner EA, Gunn RN, Tabrizi SJ, Politis M.

Brain. 2015 Oct;138(Pt 10):3016-29. doi: 10.1093/brain/awv214. Epub 2015 Jul 21.


Single versus multiple impulse control disorders in Parkinson's disease: an ¹¹C-raclopride positron emission tomography study of reward cue-evoked striatal dopamine release.

Wu K, Politis M, O'Sullivan SS, Lawrence AD, Warsi S, Bose S, Lees AJ, Piccini P.

J Neurol. 2015 Jun;262(6):1504-14. doi: 10.1007/s00415-015-7722-7. Epub 2015 Apr 18.


The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.

Smith R, Wu K, Hart T, Loane C, Brooks DJ, Björklund A, Odin P, Piccini P, Politis M.

Neurobiol Aging. 2015 Apr;36(4):1736-1742. doi: 10.1016/j.neurobiolaging.2014.12.037. Epub 2015 Jan 6.


Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome.

Giannetti P, Politis M, Su P, Turkheimer FE, Malik O, Keihaninejad S, Wu K, Waldman A, Reynolds R, Nicholas R, Piccini P.

Brain. 2015 Jan;138(Pt 1):110-9. doi: 10.1093/brain/awu331. Epub 2014 Nov 21.


In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with (18)F-PBR111 PET.

Colasanti A, Guo Q, Muhlert N, Giannetti P, Onega M, Newbould RD, Ciccarelli O, Rison S, Thomas C, Nicholas R, Muraro PA, Malik O, Owen DR, Piccini P, Gunn RN, Rabiner EA, Matthews PM.

J Nucl Med. 2014 Jul;55(7):1112-8. doi: 10.2967/jnumed.113.135129. Epub 2014 Jun 5.


Probabilistic classification learning with corrective feedback is associated with in vivo striatal dopamine release in the ventral striatum, while learning without feedback is not.

Wilkinson L, Tai YF, Lin CS, Lagnado DA, Brooks DJ, Piccini P, Jahanshahi M.

Hum Brain Mapp. 2014 Oct;35(10):5106-15. doi: 10.1002/hbm.22536. Epub 2014 Apr 28.


Problematic Internet use in Parkinson's disease.

Wu K, Politis M, O'Sullivan SS, Lawrence AD, Warsi S, Lees A, Piccini P.

Parkinsonism Relat Disord. 2014 May;20(5):482-7. doi: 10.1016/j.parkreldis.2014.01.019. Epub 2014 Feb 5.


Clinical peculiarities of tuberculosis.

Piccini P, Chiappini E, Tortoli E, de Martino M, Galli L.

BMC Infect Dis. 2014;14 Suppl 1:S4. doi: 10.1186/1471-2334-14-S1-S4. Epub 2014 Jan 8. Review.


Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients.

Politis M, Wu K, Loane C, Brooks DJ, Kiferle L, Turkheimer FE, Bain P, Molloy S, Piccini P.

J Clin Invest. 2014 Mar;124(3):1340-9. doi: 10.1172/JCI71640. Epub 2014 Feb 17.


Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: an in vivo [(11)C](R)-PK11195-PET pilot study.

Giannetti P, Politis M, Su P, Turkheimer F, Malik O, Keihaninejad S, Wu K, Reynolds R, Nicholas R, Piccini P.

Neurobiol Dis. 2014 May;65:203-10. doi: 10.1016/j.nbd.2014.01.018. Epub 2014 Feb 6.


Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports.

Kefalopoulou Z, Politis M, Piccini P, Mencacci N, Bhatia K, Jahanshahi M, Widner H, Rehncrona S, Brundin P, Björklund A, Lindvall O, Limousin P, Quinn N, Foltynie T.

JAMA Neurol. 2014 Jan;71(1):83-7. doi: 10.1001/jamaneurol.2013.4749.

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