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Items: 15

1.

Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: Mechanisms and implications.

Lee RH, Piatt R, Dhenge A, Lozano ML, Palma-Barqueros V, Rivera J, Bergmeier W.

Sci Transl Med. 2019 Dec 11;11(522). pii: eaay0203. doi: 10.1126/scitranslmed.aay0203.

PMID:
31826978
2.

Ether lipid metabolism by AADACL1 regulates platelet function and thrombosis.

Holly SP, Gera N, Wang P, Wilson A, Guan Z, Lin L, Cooley B, Alfar HR, Patil RG, Piatt R, Leisner TM, Bergmeier W, Majumder R, Parise LV.

Blood Adv. 2019 Nov 26;3(22):3818-3828. doi: 10.1182/bloodadvances.2018030767.

3.

Chronic, Twice-Daily Dosing of an NK2 Receptor Agonist [Lys5,MeLeu9,Nle10]-NKA(4-10), Produces Consistent Drug-Induced Micturition and Defecation in Chronic Spinal Rats.

Marson L, Piatt RK 2nd, Katofiasc MA, Bobbitt C, Thor KB.

J Neurotrauma. 2020 Mar 15;37(6):868-876. doi: 10.1089/neu.2019.6676. Epub 2019 Nov 13.

PMID:
31642371
4.

Functional redundancy between RAP1 isoforms in murine platelet production and function.

Stefanini L, Lee RH, Paul DS, O'Shaughnessy EC, Ghalloussi D, Jones CI, Boulaftali Y, Poe KO, Piatt R, Kechele DO, Caron KM, Hahn KM, Gibbins JM, Bergmeier W.

Blood. 2018 Nov 1;132(18):1951-1962. doi: 10.1182/blood-2018-03-838714. Epub 2018 Aug 21.

5.

Small molecule targeting the Rac1-NOX2 interaction prevents collagen-related peptide and thrombin-induced reactive oxygen species generation and platelet activation.

Akbar H, Duan X, Piatt R, Saleem S, Davis AK, Tandon NN, Bergmeier W, Zheng Y.

J Thromb Haemost. 2018 Oct;16(10):2083-2096. doi: 10.1111/jth.14240. Epub 2018 Aug 13.

6.

Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets.

Casari C, Paul DS, Susen S, Lavenu-Bombled C, Harroche A, Piatt R, Poe KO, Lee RH, Bryckaert M, Christophe OD, Lenting PJ, Denis CV, Bergmeier W.

Blood Adv. 2018 Jun 26;2(12):1417-1428. doi: 10.1182/bloodadvances.2017014290.

7.

Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice.

Paul DS, Casari C, Wu C, Piatt R, Pasala S, Campbell RA, Poe KO, Ghalloussi D, Lee RH, Rotty JD, Cooley BC, Machlus KR, Italiano JE Jr, Weyrich AS, Bear JE, Bergmeier W.

Blood Adv. 2017 Aug 8;1(18):1398-1408. doi: 10.1182/bloodadvances.2017006973.

8.

Effects of ibrutinib treatment on murine platelet function during inflammation and in primary hemostasis.

Lee RH, Piatt R, Conley PB, Bergmeier W.

Haematologica. 2017 Mar;102(3):e89-e92. doi: 10.3324/haematol.2016.155978. Epub 2016 Dec 15. No abstract available.

9.

The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling.

Battram AM, Durrant TN, Agbani EO, Heesom KJ, Paul DS, Piatt R, Poole AW, Cullen PJ, Bergmeier W, Moore SF, Hers I.

J Biol Chem. 2017 Feb 3;292(5):1691-1704. doi: 10.1074/jbc.M116.746867. Epub 2016 Nov 30.

10.

Mice Expressing Low Levels of CalDAG-GEFI Exhibit Markedly Impaired Platelet Activation With Minor Impact on Hemostasis.

Piatt R, Paul DS, Lee RH, McKenzie SE, Parise LV, Cowley DO, Cooley BC, Bergmeier W.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1838-46. doi: 10.1161/ATVBAHA.116.307874. Epub 2016 Jul 14.

11.

CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice.

Boulaftali Y, Owens AP 3rd, Beale A, Piatt R, Casari C, Lee RH, Conley PB, Paul DS, Mackman N, Bergmeier W.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):792-9. doi: 10.1161/ATVBAHA.115.306347. Epub 2016 Mar 17.

12.

RASA3 is a critical inhibitor of RAP1-dependent platelet activation.

Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W.

J Clin Invest. 2015 Apr;125(4):1419-32. doi: 10.1172/JCI77993. Epub 2015 Feb 23.

13.

Novel mouse hemostasis model for real-time determination of bleeding time and hemostatic plug composition.

Getz TM, Piatt R, Petrich BG, Monroe D, Mackman N, Bergmeier W.

J Thromb Haemost. 2015 Mar;13(3):417-25. doi: 10.1111/jth.12802. Epub 2015 Jan 9.

14.

A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.

Stefanini L, Ye F, Snider AK, Sarabakhsh K, Piatt R, Paul DS, Bergmeier W, Petrich BG.

Blood. 2014 Apr 24;123(17):2722-31. doi: 10.1182/blood-2013-12-543363. Epub 2014 Feb 28.

15.

Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation.

Holly SP, Chang JW, Li W, Niessen S, Phillips RM, Piatt R, Black JL, Smith MC, Boulaftali Y, Weyrich AS, Bergmeier W, Cravatt BF, Parise LV.

Chem Biol. 2013 Sep 19;20(9):1125-34. doi: 10.1016/j.chembiol.2013.07.011. Epub 2013 Aug 29.

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