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Items: 1 to 50 of 107

1.

Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas.

Sangiolo D, Mesiano G, Gammaitoni L, Leuci V, Todorovic M, Giraudo L, Cammarata C, Dell'Aglio C, D'Ambrosio L, Pisacane A, Sarotto I, Miano S, Ferrero I, Carnevale-Schianca F, Pignochino Y, Sassi F, Bertotti A, Piacibello W, Fagioli F, Aglietta M, Grignani G.

Cancer Res. 2014 Jan 1;74(1):119-29. doi: 10.1158/0008-5472.CAN-13-1559. Epub 2013 Dec 19.

2.

Ex vivo allogeneic stimulation significantly improves expansion of cytokine-induced killer cells without increasing their alloreactivity across HLA barriers.

Todorovic M, Mesiano G, Gammaitoni L, Leuci V, Giraudo Diego L, Cammarata C, Jordaney N, Carnevale-Schianca F, Gallo S, Fagioli F, Piacibello W, Elia AR, Pignochino Y, Dell'aglio C, Grignani G, Cignetti A, Aglietta M, Sangiolo D.

J Immunother. 2012 Sep;35(7):579-86.

PMID:
22892454
3.

FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.

Itkin T, Ludin A, Gradus B, Gur-Cohen S, Kalinkovich A, Schajnovitz A, Ovadya Y, Kollet O, Canaani J, Shezen E, Coffin DJ, Enikolopov GN, Berg T, Piacibello W, Hornstein E, Lapidot T.

Blood. 2012 Aug 30;120(9):1843-55. doi: 10.1182/blood-2011-11-394692. Epub 2012 May 29.

PMID:
22645180
4.

Cytokine-induced killer (CIK) cells as feasible and effective adoptive immunotherapy for the treatment of solid tumors.

Mesiano G, Todorovic M, Gammaitoni L, Leuci V, Giraudo Diego L, Carnevale-Schianca F, Fagioli F, Piacibello W, Aglietta M, Sangiolo D.

Expert Opin Biol Ther. 2012 Jun;12(6):673-84. doi: 10.1517/14712598.2012.675323. Epub 2012 Apr 14. Review.

PMID:
22500889
5.

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice.

Salvestrini V, Zini R, Rossi L, Gulinelli S, Manfredini R, Bianchi E, Piacibello W, Caione L, Migliardi G, Ricciardi MR, Tafuri A, Romano M, Salati S, Di Virgilio F, Ferrari S, Baccarani M, Ferrari D, Lemoli RM.

Blood. 2012 Jan 5;119(1):217-26. doi: 10.1182/blood-2011-07-370775. Epub 2011 Nov 3.

PMID:
22053107
6.

Transient proteasome inhibition as a strategy to enhance lentiviral transduction of hematopoietic CD34(+) cells and T lymphocytes: implications for the use of low viral doses and large-size vectors.

Leuci V, Mesiano G, Gammaitoni L, Cammarata C, Capellero S, Todorovic M, Jordaney N, Circosta P, Elia A, Lesnikova M, Georges GE, Piacibello W, Fagioli F, Cignetti A, Aglietta M, Sangiolo D.

J Biotechnol. 2011 Dec 10;156(3):218-26. doi: 10.1016/j.jbiotec.2011.09.001. Epub 2011 Sep 10.

PMID:
21933686
7.

Gene-modified T lymphocytes in the setting of hematopoietic cell transplantation: potential benefits and possible risks.

Sangiolo D, Leuci V, Gallo S, Aglietta M, Piacibello W.

Expert Opin Biol Ther. 2011 May;11(5):655-66. doi: 10.1517/14712598.2011.565325. Epub 2011 Mar 7. Review.

PMID:
21375466
8.

Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines.

Ferrari D, Gulinelli S, Salvestrini V, Lucchetti G, Zini R, Manfredini R, Caione L, Piacibello W, Ciciarello M, Rossi L, Idzko M, Ferrari S, Di Virgilio F, Lemoli RM.

Exp Hematol. 2011 Mar;39(3):360-74, 374.e1-5. doi: 10.1016/j.exphem.2010.12.001. Epub 2010 Dec 9.

PMID:
21145936
9.

Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal.

Skorokhod OA, Caione L, Marrocco T, Migliardi G, Barrera V, Arese P, Piacibello W, Schwarzer E.

Blood. 2010 Nov 18;116(20):4328-37. doi: 10.1182/blood-2010-03-272781. Epub 2010 Aug 4.

PMID:
20686121
10.

Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling.

Tesio M, Golan K, Corso S, Giordano S, Schajnovitz A, Vagima Y, Shivtiel S, Kalinkovich A, Caione L, Gammaitoni L, Laurenti E, Buss EC, Shezen E, Itkin T, Kollet O, Petit I, Trumpp A, Christensen J, Aglietta M, Piacibello W, Lapidot T.

Blood. 2011 Jan 13;117(2):419-28. doi: 10.1182/blood-2009-06-230359. Epub 2010 Jun 28.

11.

Efficient transcriptional targeting of human hematopoietic stem cells and blood cell lineages by lentiviral vectors containing the regulatory element of the Wiskott-Aldrich syndrome gene.

Leuci V, Gammaitoni L, Capellero S, Sangiolo D, Mesuraca M, Bond HM, Migliardi G, Cammarata C, Aglietta M, Morrone G, Piacibello W.

Stem Cells. 2009 Nov;27(11):2815-23. doi: 10.1002/stem.224.

12.

Cytokine induced killer cells as adoptive immunotherapy strategy to augment graft versus tumor after hematopoietic cell transplantation.

Sangiolo D, Mesiano G, Carnevale-Schianca F, Piacibello W, Aglietta M, Cignetti A.

Expert Opin Biol Ther. 2009 Jul;9(7):831-40. doi: 10.1517/14712590903005552. Review.

PMID:
19463075
13.

Blood-forming stem cells are nervous: direct and indirect regulation of immature human CD34+ cells by the nervous system.

Kalinkovich A, Spiegel A, Shivtiel S, Kollet O, Jordaney N, Piacibello W, Lapidot T.

Brain Behav Immun. 2009 Nov;23(8):1059-65. doi: 10.1016/j.bbi.2009.03.008. Epub 2009 Mar 31. Review.

PMID:
19341792
14.

Granulocyte-colony stimulating factor upregulates ErbB2 expression on breast cancer cell lines and converts primary resistance to trastuzumab.

Cavalloni G, Sarotto I, Pignochino Y, Gammaitoni L, Migliardi G, Sgro L, Piacibello W, Risio M, Aglietta M, Leone F.

Anticancer Drugs. 2008 Aug;19(7):689-96. doi: 10.1097/CAD.0b013e3283050083.

PMID:
18594210
15.

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.

Sierra JR, Corso S, Caione L, Cepero V, Conrotto P, Cignetti A, Piacibello W, Kumanogoh A, Kikutani H, Comoglio PM, Tamagnone L, Giordano S.

J Exp Med. 2008 Jul 7;205(7):1673-85. doi: 10.1084/jem.20072602. Epub 2008 Jun 16.

16.

Sustained long-term engraftment and transgene expression of peripheral blood CD34+ cells transduced with third-generation lentiviral vectors.

Tesio M, Gammaitoni L, Gunetti M, Leuci V, Pignochino Y, Jordaney N, Capellero S, Cammarata C, Caione L, Migliaretti G, Fagioli F, Tabilio A, Aglietta M, Piacibello W.

Stem Cells. 2008 Jun;26(6):1620-7. doi: 10.1634/stemcells.2008-0161. Epub 2008 Mar 27.

17.

Refreezing of cord blood hematopoietic stem cells for allogenic transplantation: in vitro and in vivo validation of a clinical phase I/II protocol in European and Italian Good Manufacturing Practice conditions.

Gunetti M, Ferrero I, Rustichelli D, Berger M, Gammaitoni L, Timeus F, Piacibello W, Aglietta M, Fagioli F.

Exp Hematol. 2008 Feb;36(2):235-43. doi: 10.1016/j.exphem.2007.08.030.

PMID:
18206730
18.

Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia.

Hong D, Gupta R, Ancliff P, Atzberger A, Brown J, Soneji S, Green J, Colman S, Piacibello W, Buckle V, Tsuzuki S, Greaves M, Enver T.

Science. 2008 Jan 18;319(5861):336-9. doi: 10.1126/science.1150648.

19.

Somatic mutations of epidermal growth factor receptor in bile duct and gallbladder carcinoma.

Leone F, Cavalloni G, Pignochino Y, Sarotto I, Ferraris R, Piacibello W, Venesio T, Capussotti L, Risio M, Aglietta M.

Clin Cancer Res. 2006 Mar 15;12(6):1680-5.

20.

Multilineage engraftment of refrozen cord blood hematopoietic progenitors in NOD/SCID mice.

Timeus F, Crescenzio N, Sanavio F, Fazio L, Doria A, Foglia L, Pignochino Y, Berger M, Piacibello W, Madon E, Cordero di Montezemolo L, Fagioli F.

Haematologica. 2006 Mar;91(3):369-72.

21.

[Stem cells: overview].

Piacibello W, Pignochino Y.

Pathologica. 2005 Aug;97(4):184. Italian. No abstract available.

PMID:
16440646
22.

Serial transplantations in nonobese diabetic/severe combined immunodeficiency mice of transduced human CD34+ cord blood cells: efficient oncoretroviral gene transfer and ex vivo expansion under serum-free conditions.

Gammaitoni L, Lucchi S, Bruno S, Tesio M, Gunetti M, Pignochino Y, Migliardi G, Lazzari L, Aglietta M, Rebulla P, Piacibello W.

Stem Cells. 2006 May;24(5):1201-12. Epub 2006 Jan 12.

23.

Tumor cell purging by ex vivo expansion of hemopoietic stem cells from breast cancer patients combined with targeting ErbB receptors.

Leone F, Cavalloni G, Gunetti M, Pignochino Y, Piacibello W, Aglietta M.

Biol Blood Marrow Transplant. 2006 Jan;12(1):68-74.

24.

Proliferative senescence in hematopoietic stem cells during ex-vivo expansion.

Piacibello W, Gammaitoni L, Pignochino Y.

Folia Histochem Cytobiol. 2005;43(4):197-202. Review.

25.

Feasibility of cord blood stem cell manipulation with high-energy shock waves: an in vitro and in vivo study.

Berger M, Frairia R, Piacibello W, Sanavio F, Palmero A, Venturi C, Pignochino Y, Berta L, Madon E, Aglietta M, Fagioli F.

Exp Hematol. 2005 Nov;33(11):1371-87.

PMID:
16263422
26.

Cycling G1 CD34+/CD38+ cells potentiate the motility and engraftment of quiescent G0 CD34+/CD38-/low severe combined immunodeficiency repopulating cells.

Byk T, Kahn J, Kollet O, Petit I, Samira S, Shivtiel S, Ben-Hur H, Peled A, Piacibello W, Lapidot T.

Stem Cells. 2005 Apr;23(4):561-74.

27.

Involvement of chemokine receptor 4/stromal cell-derived factor 1 system during osteosarcoma tumor progression.

Perissinotto E, Cavalloni G, Leone F, Fonsato V, Mitola S, Grignani G, Surrenti N, Sangiolo D, Bussolino F, Piacibello W, Aglietta M.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):490-7.

28.

Vasculogenic potential of long term repopulating cord blood progenitors.

Droetto S, Viale A, Primo L, Jordaney N, Bruno S, Pagano M, Piacibello W, Bussolino F, Aglietta M.

FASEB J. 2004 Aug;18(11):1273-5. Epub 2004 Jun 18.

PMID:
15208264
29.

Hemozoin- and 4-hydroxynonenal-mediated inhibition of erythropoiesis. Possible role in malarial dyserythropoiesis and anemia.

Giribaldi G, Ulliers D, Schwarzer E, Roberts I, Piacibello W, Arese P.

Haematologica. 2004 Apr;89(4):492-3.

30.

Fast but durable megakaryocyte repopulation and platelet production in NOD/SCID mice transplanted with ex-vivo expanded human cord blood CD34+ cells.

Bruno S, Gunetti M, Gammaitoni L, Perissinotto E, Caione L, Sanavio F, Fagioli F, Aglietta M, Piacibello W.

Stem Cells. 2004;22(2):135-43.

31.

Elevated telomerase activity and minimal telomere loss in cord blood long-term cultures with extensive stem cell replication.

Gammaitoni L, Weisel KC, Gunetti M, Wu KD, Bruno S, Pinelli S, Bonati A, Aglietta M, Moore MA, Piacibello W.

Blood. 2004 Jun 15;103(12):4440-8. Epub 2004 Jan 15.

PMID:
14726371
32.

Expression of the c-ErbB-2/HER2 proto-oncogene in normal hematopoietic cells.

Leone F, Perissinotto E, Cavalloni G, Fonsato V, Bruno S, Surrenti N, Hong D, Capaldi A, Geuna M, Piacibello W, Aglietta M.

J Leukoc Biol. 2003 Oct;74(4):593-601. Epub 2003 Jul 15.

PMID:
12960261
33.
34.

In vitro and in vivo megakaryocyte differentiation of fresh and ex-vivo expanded cord blood cells: rapid and transient megakaryocyte reconstitution.

Bruno S, Gunetti M, Gammaitoni L, Danè A, Cavalloni G, Sanavio F, Fagioli F, Aglietta M, Piacibello W.

Haematologica. 2003 Apr;88(4):379-87.

35.

Ex vivo expansion of human adult stem cells capable of primary and secondary hemopoietic reconstitution.

Gammaitoni L, Bruno S, Sanavio F, Gunetti M, Kollet O, Cavalloni G, Falda M, Fagioli F, Lapidot T, Aglietta M, Piacibello W.

Exp Hematol. 2003 Mar;31(3):261-70.

PMID:
12644024
36.

Vascular Endothelial Growth Factor and Its Receptor KDR/flk-1 Play Important Roles in Hematopoiesis.

Hong DL, Zhang YZ, Piacibello W, Aglietta M.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2001 Sep;9(3):268-272.

PMID:
12578605
37.

Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice. Nonobese diabetic/severe combined immunodeficient.

Piacibello W, Bruno S, Sanavio F, Droetto S, Gunetti M, Ailles L, Santoni de Sio F, Viale A, Gammaitoni L, Lombardo A, Naldini L, Aglietta M.

Blood. 2002 Dec 15;100(13):4391-400.

PMID:
12453876
38.

Molecular evidence of lentiviral vector-mediated gene transfer into human self-renewing, multi-potent, long-term NOD/SCID repopulating hematopoietic cells.

Ailles L, Schmidt M, Santoni de Sio FR, Glimm H, Cavalieri S, Bruno S, Piacibello W, Von Kalle C, Naldini L.

Mol Ther. 2002 Nov;6(5):615-26.

39.

Human CD34(+)CXCR4(-) sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation.

Kollet O, Petit I, Kahn J, Samira S, Dar A, Peled A, Deutsch V, Gunetti M, Piacibello W, Nagler A, Lapidot T.

Blood. 2002 Oct 15;100(8):2778-86.

PMID:
12351385
40.

MEK-ERK pathway is expressed but not activated in high proliferating, self-renewing cord blood hematopoietic progenitors.

Bonati A, Lunghi P, Gammaitoni L, Pinelli S, Ridolo E, Dall'Aglio PP, Piacibello W, Aglietta M.

Hematol J. 2002;3(2):105-13.

PMID:
12032872
41.

Role of different medium and growth factors on placental blood stem cell expansion: an in vitro and in vivo study.

Berger M, Fagioli F, Piacibello W, Sanavio F, Mareschi K, Biasin E, Bruno S, Gammaitoni L, Gunetti M, Nesi F, Madon E, Aglietta M.

Bone Marrow Transplant. 2002 Mar;29(5):443-8.

42.

Isolation of human mesenchymal stem cells: bone marrow versus umbilical cord blood.

Mareschi K, Biasin E, Piacibello W, Aglietta M, Madon E, Fagioli F.

Haematologica. 2001 Oct;86(10):1099-100. No abstract available.

43.

Different growth factor requirements for the ex vivo amplification of transplantable human cord blood cells in a NOD/SCID mouse model.

Bruno S, Gammaitoni L, Gunetti M, Sanavio F, Fagioli F, Aglietta M, Piacibello W.

J Biol Regul Homeost Agents. 2001 Jan-Mar;15(1):38-48.

PMID:
11388743
44.

Detection of breast cancer cell contamination in leukapheresis product by real-time quantitative polymerase chain reaction.

Leone F, Perissinotto E, Viale A, Cavalloni G, Taraglio S, Capaldi A, Piacibello W, Torchio B, Aglietta M.

Bone Marrow Transplant. 2001 Mar;27(5):517-23.

45.

Negative influence of IL3 on the expansion of human cord blood in vivo long-term repopulating stem cells.

Piacibello W, Gammaitoni L, Bruno S, Gunetti M, Fagioli F, Cavalloni G, Aglietta M.

J Hematother Stem Cell Res. 2000 Dec;9(6):945-56.

PMID:
11177609
46.

The involvement of human-nuc gene in polyploidization of K562 cell line.

Cavalloni G, Danè A, Piacibello W, Bruno S, Lamas E, Bréchot C, Aglietta M.

Exp Hematol. 2000 Dec;28(12):1432-40.

PMID:
11146165
47.

The role of c-Mpl ligands in the expansion of cord blood hematopoietic progenitors.

Piacibello W, Sanavio F, Garetto L, Severino A, Danè A, Gammaitoni L, Aglietta M.

Stem Cells. 1998;16 Suppl 2:243-8.

48.

Ex vivo expansion of megakaryocytes.

Piacibello W, Garetto L, Aglietta M.

Transfus Sci. 2000 Feb-Apr;22(1-2):107-10. No abstract available.

PMID:
10771397
49.

Engraftment in nonobese diabetic severe combined immunodeficient mice of human CD34(+) cord blood cells after ex vivo expansion: evidence for the amplification and self-renewal of repopulating stem cells.

Piacibello W, Sanavio F, Severino A, Danè A, Gammaitoni L, Fagioli F, Perissinotto E, Cavalloni G, Kollet O, Lapidot T, Aglietta M.

Blood. 1999 Jun 1;93(11):3736-49.

PMID:
10339480
50.

Ex vivo expansion of cord blood progenitors.

Piacibello W, Sanavio F, Severino A, Garetto L, Danè A, Gammaitoni L, Aglietta M.

Vox Sang. 1998;74 Suppl 2:457-62. Review.

PMID:
9704481

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