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Best matches for Piñeyro G[au]:

Molecular Pharmacology of δ-Opioid Receptors. Gendron L et al. Pharmacol Rev. (2016)

Practical guide for calculating and representing biased signaling by GPCR ligands: A stepwise approach. Nagi K et al. Methods. (2016)

Analyzing biased responses of GPCR ligands. Benredjem B et al. Curr Opin Pharmacol. (2017)

Search results

Items: 41

1.

Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.

Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, Laporte SA.

Sci Signal. 2018 Dec 4;11(559). pii: eaat1631. doi: 10.1126/scisignal.aat1631.

PMID:
30514808
2.

Delta opioid receptors recycle to the membrane after sorting to the degradation path.

Charfi I, Abdallah K, Gendron L, Pineyro G.

Cell Mol Life Sci. 2018 Jun;75(12):2257-2271. doi: 10.1007/s00018-017-2732-5. Epub 2017 Dec 29.

PMID:
29288293
3.

Analyzing biased responses of GPCR ligands.

Benredjem B, Dallaire P, Pineyro G.

Curr Opin Pharmacol. 2017 Feb;32:71-76. doi: 10.1016/j.coph.2016.11.008. Epub 2016 Dec 6. Review.

PMID:
27930943
4.

Molecular Pharmacology of δ-Opioid Receptors.

Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G.

Pharmacol Rev. 2016 Jul;68(3):631-700. doi: 10.1124/pr.114.008979. Review.

5.

Practical guide for calculating and representing biased signaling by GPCR ligands: A stepwise approach.

Nagi K, Pineyro G.

Methods. 2016 Jan 1;92:78-86. doi: 10.1016/j.ymeth.2015.09.010. Epub 2015 Sep 11. Review.

PMID:
26364590
6.

Design and construction of conformational biosensors to monitor ion channel activation: A prototype FlAsH/BRET-approach to Kir3 channels.

Robertson DN, Sleno R, Nagi K, Pétrin D, Hébert TE, Pineyro G.

Methods. 2016 Jan 1;92:19-35. doi: 10.1016/j.ymeth.2015.07.011. Epub 2015 Jul 22.

PMID:
26210401
7.

Kir3 channels undergo arrestin-dependant internalization following delta opioid receptor activation.

Nagi K, Charfi I, Pineyro G.

Cell Mol Life Sci. 2015 Sep;72(18):3543-57. doi: 10.1007/s00018-015-1899-x. Epub 2015 Apr 22.

PMID:
25900661
8.

Kir3 channel signaling complexes: focus on opioid receptor signaling.

Nagi K, Pineyro G.

Front Cell Neurosci. 2014 Jul 8;8:186. doi: 10.3389/fncel.2014.00186. eCollection 2014. Review.

9.

Label-free monitoring of μ-opioid receptor-mediated signaling.

Bourassa P, Tudashki HB, Pineyro G, Grandbois M, Gendron L.

Mol Pharmacol. 2014 Aug;86(2):138-49. doi: 10.1124/mol.114.093450. Epub 2014 May 29.

10.

Identifying ligand-specific signalling within biased responses: focus on δ opioid receptor ligands.

Charfi I, Audet N, Bagheri Tudashki H, Pineyro G.

Br J Pharmacol. 2015 Jan;172(2):435-48. doi: 10.1111/bph.12705. Epub 2014 Jul 1. Review.

11.

Endocytic profiles of δ-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses.

Tudashki HB, Robertson DN, Schiller PW, Pineyro G.

Mol Pharmacol. 2014 Jan;85(1):148-61. doi: 10.1124/mol.113.089003. Epub 2013 Oct 30.

12.

Ligand- and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists.

Charfi I, Nagi K, Mnie-Filali O, Thibault D, Balboni G, Schiller PW, Trudeau LE, Pineyro G.

Cell Mol Life Sci. 2014 Apr;71(8):1529-46.

13.

Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.

Richard-Lalonde M, Nagi K, Audet N, Sleno R, Amraei M, Hogue M, Balboni G, Schiller PW, Bouvier M, Hébert TE, Pineyro G.

Mol Pharmacol. 2013 Feb;83(2):416-28. doi: 10.1124/mol.112.081950. Epub 2012 Nov 21.

14.

Differential association of receptor-Gβγ complexes with β-arrestin2 determines recycling bias and potential for tolerance of δ opioid receptor agonists.

Audet N, Charfi I, Mnie-Filali O, Amraei M, Chabot-Doré AJ, Millecamps M, Stone LS, Pineyro G.

J Neurosci. 2012 Apr 4;32(14):4827-40. doi: 10.1523/JNEUROSCI.3734-11.2012.

15.

Using BRET to detect ligand-specific conformational changes in preformed signalling complexes.

Audet N, Piñeyro G.

Methods Mol Biol. 2011;756:149-63. doi: 10.1007/978-1-61779-160-4_7.

PMID:
21870224
16.

Regulation of opioid receptor signalling: implications for the development of analgesic tolerance.

Nagi K, Piñeyro G.

Mol Brain. 2011 Jun 13;4:25. doi: 10.1186/1756-6606-4-25. Review.

17.

Neurotensin triggers dopamine D2 receptor desensitization through a protein kinase C and beta-arrestin1-dependent mechanism.

Thibault D, Albert PR, Pineyro G, Trudeau LÉ.

J Biol Chem. 2011 Mar 18;286(11):9174-84. doi: 10.1074/jbc.M110.166454. Epub 2011 Jan 13.

18.

Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat.

Lucas G, Du J, Romeas T, Mnie-Filali O, Haddjeri N, Piñeyro G, Debonnel G.

PLoS One. 2010 Feb 16;5(2):e9253. doi: 10.1371/journal.pone.0009253.

19.

Serotonin 4 receptor (5-HT4R) internalization is isoform-specific: effects of 5-HT and RS67333 on isoforms A and B.

Mnie-Filali O, Amraei MG, Benmbarek S, Archer-Lahlou E, Peñas-Cazorla R, Vilaró MT, Boye SM, Piñeyro G.

Cell Signal. 2010 Mar;22(3):501-9. doi: 10.1016/j.cellsig.2009.11.004.

PMID:
19922792
20.

Simultaneous anhedonia and exaggerated locomotor activation in an animal model of depression.

Romeas T, Morissette MC, Mnie-Filali O, Piñeyro G, Boye SM.

Psychopharmacology (Berl). 2009 Aug;205(2):293-303. doi: 10.1007/s00213-009-1539-y. Epub 2009 Apr 29.

PMID:
19404615
21.

Membrane signalling complexes: implications for development of functionally selective ligands modulating heptahelical receptor signalling.

Piñeyro G.

Cell Signal. 2009 Feb;21(2):179-85. doi: 10.1016/j.cellsig.2008.08.013. Epub 2008 Aug 28. Review.

PMID:
18790047
22.

Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

Audet N, Galés C, Archer-Lahlou E, Vallières M, Schiller PW, Bouvier M, Pineyro G.

J Biol Chem. 2008 May 30;283(22):15078-88. doi: 10.1074/jbc.M707941200. Epub 2008 Apr 1.

23.

Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling.

Archer-Lahlou E, Audet N, Amraei MG, Huard K, Paquin-Gobeil M, Pineyro G.

J Cell Mol Med. 2009 Jan;13(1):147-63. doi: 10.1111/j.1582-4934.2008.00308.x. Epub 2008 Mar 19.

24.

Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action.

Lucas G, Rymar VV, Du J, Mnie-Filali O, Bisgaard C, Manta S, Lambas-Senas L, Wiborg O, Haddjeri N, Piñeyro G, Sadikot AF, Debonnel G.

Neuron. 2007 Sep 6;55(5):712-25.

25.

Ligand-specific receptor states: implications for opiate receptor signalling and regulation.

Piñeyro G, Archer-Lahlou E.

Cell Signal. 2007 Jan;19(1):8-19. Epub 2006 Jun 7. Review.

PMID:
16842969
26.

Internalization and Src activity regulate the time course of ERK activation by delta opioid receptor ligands.

Audet N, Paquin-Gobeil M, Landry-Paquet O, Schiller PW, Piñeyro G.

J Biol Chem. 2005 Mar 4;280(9):7808-16. Epub 2005 Jan 4.

27.

Reciprocal regulation of agonist and inverse agonist signaling efficacy upon short-term treatment of the human delta-opioid receptor with an inverse agonist.

Piñeyro G, Azzi M, deLéan A, Schiller PW, Bouvier M.

Mol Pharmacol. 2005 Jan;67(1):336-48. Epub 2004 Oct 20.

28.

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors.

Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, Bouvier M, Piñeyro G.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11406-11. Epub 2003 Sep 17.

29.

Allosteric effects of G protein overexpression on the binding of beta-adrenergic ligands with distinct inverse efficacies.

Azzi M, Piñeyro G, Pontier S, Parent S, Ansanay H, Bouvier M.

Mol Pharmacol. 2001 Nov;60(5):999-1007.

30.

Short-term inverse-agonist treatment induces reciprocal changes in delta-opioid agonist and inverse-agonist binding capacity.

Piñeyro G, Azzi M, De Léan A, Schiller P, Bouvier M.

Mol Pharmacol. 2001 Oct;60(4):816-27.

31.

Autoregulation of serotonin neurons: role in antidepressant drug action.

Piñeyro G, Blier P.

Pharmacol Rev. 1999 Sep;51(3):533-91. Review. No abstract available.

32.

Role of somatodendritic 5-HT autoreceptors in modulating 5-HT neurotransmission.

Blier P, Piñeyro G, el Mansari M, Bergeron R, de Montigny C.

Ann N Y Acad Sci. 1998 Dec 15;861:204-16. Review.

PMID:
9928258
34.
35.

Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice.

Piñeyro G, Castanon N, Hen R, Blier P.

Neuroreport. 1995 Dec 29;7(1):353-9.

PMID:
8742487
36.

5-HT1D receptors regulate 5-HT release in the rat raphe nuclei. In vivo voltammetry and in vitro superfusion studies.

Piñeyro G, de Montigny C, Blier P.

Neuropsychopharmacology. 1995 Nov;13(3):249-60.

37.

Effect of prolonged administration of tianeptine on 5-HT neurotransmission: an electrophysiological study in the rat hippocampus and dorsal raphe.

Piñeyro G, Deveault L, de Montigny C, Blier P.

Naunyn Schmiedebergs Arch Pharmacol. 1995 Feb;351(2):119-25.

PMID:
7770094
38.

Effect of acute and prolonged tianeptine administration on the 5-HT transporter: electrophysiological, biochemical and radioligand binding studies in the rat brain.

Piñeyro G, Deveault L, Blier P, Dennis T, de Montigny C.

Naunyn Schmiedebergs Arch Pharmacol. 1995 Feb;351(2):111-8.

PMID:
7770093
39.

Desensitization of the neuronal 5-HT carrier following its long-term blockade.

Piñeyro G, Blier P, Dennis T, de Montigny C.

J Neurosci. 1994 May;14(5 Pt 2):3036-47.

40.

Electrophysiological studies on the effect of long-term 5-HT reuptake inhibition on the function of 5-HT neurons.

DE Montigny C, Pineyro G, Chaput Y, Blier P.

Clin Neuropharmacol. 1992;15 Suppl 1 Pt A:440A-441A. No abstract available.

PMID:
1323401
41.

Combined effects of midazolam and ethanol on sleep and on psychomotor performance in normal subjects.

Monti JM, Piñeyro G, Alvariño F, Labraga P.

Fundam Clin Pharmacol. 1989;3(6):613-20.

PMID:
2613161

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