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Items: 11


Green propolis increases myeloid suppressor cells and CD4+Foxp3+ cells and reduces Th2 inflammation in the lungs after allergen exposure.

Piñeros AR, de Lima MHF, Rodrigues T, Gembre AF, Bertolini TB, Fonseca MD, Berretta AA, Ramalho LNZ, Cunha FQ, Hori JI, Bonato VLD.

J Ethnopharmacol. 2019 Dec 20:112496. doi: 10.1016/j.jep.2019.112496. [Epub ahead of print]


Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.

Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL, Liu Y, Bernal-Mizrachi E, Alonso LC, Scott D, Garcia-Ocaña A, Tersey SA, Mirmira RG.

Sci Signal. 2019 Dec 3;12(610). pii: eaax0715. doi: 10.1126/scisignal.aax0715.


A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo.

Reissaus CA, Piñeros AR, Twigg AN, Orr KS, Conteh AM, Martinez MM, Kamocka MM, Day RN, Tersey SA, Mirmira RG, Dunn KW, Linnemann AK.

Sci Rep. 2019 Jun 11;9(1):8449. doi: 10.1038/s41598-019-44777-0.


Adenosine 2A Receptor Activation Attenuates Ischemia Reperfusion Injury During Extracorporeal Cardiopulmonary Resuscitation.

Mehaffey JH, Money D, Charles EJ, Schubert S, Piñeros AF, Wu D, Bontha SV, Hawkins R, Teman NR, Laubach VE, Mas VR, Tribble CG, Maluf DG, Sharma AK, Yang Z, Kron IL, Roeser ME.

Ann Surg. 2019 Jun;269(6):1176-1183. doi: 10.1097/SLA.0000000000002685.


CCR4-dependent reduction in the number and suppressor function of CD4+Foxp3+ cells augments IFN-γ-mediated pulmonary inflammation and aggravates tuberculosis pathogenesis.

Bertolini TB, Piñeros AR, Prado RQ, Gembre AF, Ramalho LNZ, Alves-Filho JC, Bonato VLD.

Cell Death Dis. 2018 Dec 21;10(1):11. doi: 10.1038/s41419-018-1240-3.


Improvement of the resistance against early Mycobacterium tuberculosis-infection in the absence of PI3Kγ enzyme is associated with increase of CD4+IL-17+ cells and neutrophils.

Cavalcanti-Neto MP, Prado RQ, Piñeros AR, Sérgio CA, Bertolini TB, Gembre AF, Ramos SG, Bonato VL.

Tuberculosis (Edinb). 2018 Dec;113:1-9. doi: 10.1016/ Epub 2018 Aug 23.


IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population.

Nascimento DC, Melo PH, Piñeros AR, Ferreira RG, Colón DF, Donate PB, Castanheira FV, Gozzi A, Czaikoski PG, Niedbala W, Borges MC, Zamboni DS, Liew FY, Cunha FQ, Alves-Filho JC.

Nat Commun. 2017 Apr 4;8:14919. doi: 10.1038/ncomms14919.


M2 macrophages or IL-33 treatment attenuate ongoing Mycobacterium tuberculosis infection.

Piñeros AR, Campos LW, Fonseca DM, Bertolini TB, Gembre AF, Prado RQ, Alves-Filho JC, Ramos SG, Russo M, Bonato VL.

Sci Rep. 2017 Jan 27;7:41240. doi: 10.1038/srep41240.


Topical Prostaglandin E Analog Restores Defective Dendritic Cell-Mediated Th17 Host Defense Against Methicillin-Resistant Staphylococcus Aureus in the Skin of Diabetic Mice.

Dejani NN, Brandt SL, Piñeros A, Glosson-Byers NL, Wang S, Son YM, Medeiros AI, Serezani CH.

Diabetes. 2016 Dec;65(12):3718-3729. Epub 2016 Sep 7.


Genetic background affects the expansion of macrophage subsets in the lungs of Mycobacterium tuberculosis-infected hosts.

Bertolini TB, de Souza AI, Gembre AF, Piñeros AR, Prado Rde Q, Silva JS, Ramalho LN, Bonato VL.

Immunology. 2016 May;148(1):102-13. doi: 10.1111/imm.12591.


Attenuation of experimental asthma by mycobacterial protein combined with CpG requires a TLR9-dependent IFN-γ-CCR2 signalling circuit.

Prado RQ, Bertolini TB, Piñeros AR, Gembre AF, Ramos SG, Silva CL, Borges MC, Bonato VL.

Clin Exp Allergy. 2015 Sep;45(9):1459-71. doi: 10.1111/cea.12564.


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