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Items: 16


TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.

Zhao Y, Wu X, Li X, Jiang LL, Gui X, Liu Y, Sun Y, Zhu B, Piña-Crespo JC, Zhang M, Zhang N, Chen X, Bu G, An Z, Huang TY, Xu H.

Neuron. 2018 Mar 7;97(5):1023-1031.e7. doi: 10.1016/j.neuron.2018.01.031.


SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration.

Huang TY, Zhao Y, Jiang LL, Li X, Liu Y, Sun Y, Piña-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H.

J Exp Med. 2017 Dec 4;214(12):3669-3685. doi: 10.1084/jem.20171413. Epub 2017 Nov 7.


MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.

Nagar S, Noveral SM, Trudler D, Lopez KM, McKercher SR, Han X, Yates JR 3rd, Piña-Crespo JC, Nakanishi N, Satoh T, Okamoto SI, Lipton SA.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4048-E4056. doi: 10.1073/pnas.1613067114. Epub 2017 May 1.


Levetiracetam inhibits oligomeric Aβ-induced glutamate release from human astrocytes.

Sanz-Blasco S, Piña-Crespo JC, Zhang X, McKercher SR, Lipton SA.

Neuroreport. 2016 Jun 15;27(9):705-9. doi: 10.1097/WNR.0000000000000601.


Astrocytes contribute to gamma oscillations and recognition memory.

Lee HS, Ghetti A, Pinto-Duarte A, Wang X, Dziewczapolski G, Galimi F, Huitron-Resendiz S, Piña-Crespo JC, Roberts AJ, Verma IM, Sejnowski TJ, Heinemann SF.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3343-52. doi: 10.1073/pnas.1410893111. Epub 2014 Jul 28.


Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neurons.

Molokanova E, Akhtar MW, Sanz-Blasco S, Tu S, Piña-Crespo JC, McKercher SR, Lipton SA.

J Neurosci. 2014 Apr 2;34(14):5023-8. doi: 10.1523/JNEUROSCI.2907-13.2014.


Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.

Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, Sason H, Stouffer DG, Buczynski MW, Solomon JP, Michael S, Powers ET, Kelly JW, Roberts A, Tong G, Fang-Newmeyer T, Parker J, Holland EA, Zhang D, Nakanishi N, Chen HS, Wolosker H, Wang Y, Parsons LH, Ambasudhan R, Masliah E, Heinemann SF, Piña-Crespo JC, Lipton SA.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2518-27. doi: 10.1073/pnas.1306832110. Epub 2013 Jun 17. Erratum in: Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13691. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3630. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3751-2.


High-frequency hippocampal oscillations activated by optogenetic stimulation of transplanted human ESC-derived neurons.

Piña-Crespo JC, Talantova M, Cho EG, Soussou W, Dolatabadi N, Ryan SD, Ambasudhan R, McKercher S, Deisseroth K, Lipton SA.

J Neurosci. 2012 Nov 7;32(45):15837-42. doi: 10.1523/JNEUROSCI.3735-12.2012.


Excitatory glycine responses of CNS myelin mediated by NR1/NR3 "NMDA" receptor subunits.

Piña-Crespo JC, Talantova M, Micu I, States B, Chen HS, Tu S, Nakanishi N, Tong G, Zhang D, Heinemann SF, Zamponi GW, Stys PK, Lipton SA.

J Neurosci. 2010 Aug 25;30(34):11501-5. doi: 10.1523/JNEUROSCI.1593-10.2010.


Motor impairment and neuronal damage following hypothermia in tropical amphibians.

Daló NL, Bracho GA, Piña-Crespo JC.

Int J Exp Pathol. 2007 Feb;88(1):1-7.


Activity of common anticonvulsant drugs on spinal seizure-induced by sudden cooling.

Piña-Crespo JC, Daló NL.

Prog Neuropsychopharmacol Biol Psychiatry. 2006 Sep 30;30(7):1202-8. Epub 2006 Apr 19.


Exocytic trafficking is required for nicotine-induced up-regulation of alpha 4 beta 2 nicotinic acetylcholine receptors.

Darsow T, Booker TK, Piña-Crespo JC, Heinemann SF.

J Biol Chem. 2005 May 6;280(18):18311-20. Epub 2005 Mar 1.


Subtypes of NMDA receptors in new-born rat hippocampal granule cells.

Piña-Crespo JC, Gibb AJ.

J Physiol. 2002 May 15;541(Pt 1):41-64.


Ketamine reduces lethality on the acute ammonia intoxication in mice.

Boscán PL, Piña-Crespo JC, Daló NL.

Invest Clin. 1996 Jun;37(2):129-35.


Ketamine abolishes the tonic phase of the seizures evoked by sudden cooling of toad isolated spinal cords.

Daló NL, Piña-Crespo JC.

Neuropharmacology. 1992 May;31(5):509-12.


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