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Items: 12


Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax.

Gupta SC, Reuter S, Phromnoi K, Park B, Hema PS, Nair M, Aggarwal BB.

J Biol Chem. 2016 Aug 5;291(32):16925. doi: 10.1074/jbc.A110.191379. No abstract available.


Morin inhibits STAT3 tyrosine 705 phosphorylation in tumor cells through activation of protein tyrosine phosphatase SHP1.

Gupta SC, Phromnoi K, Aggarwal BB.

Biochem Pharmacol. 2013 Apr 1;85(7):898-912. doi: 10.1016/j.bcp.2012.12.018. Epub 2012 Dec 29.


Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug.

Reuter S, Gupta SC, Phromnoi K, Aggarwal BB.

Br J Pharmacol. 2012 Apr;165(7):2127-39. doi: 10.1111/j.1476-5381.2011.01702.x.


Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1.

Phromnoi K, Prasad S, Gupta SC, Kannappan R, Reuter S, Limtrakul P, Aggarwal BB.

Mol Pharmacol. 2011 Nov;80(5):889-99. doi: 10.1124/mol.111.073676. Epub 2011 Aug 4.


Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Aggarwal BB, Prasad S, Reuter S, Kannappan R, Yadev VR, Park B, Kim JH, Gupta SC, Phromnoi K, Sundaram C, Prasad S, Chaturvedi MM, Sung B.

Curr Drug Targets. 2011 Oct;12(11):1595-653.


Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer.

Reuter S, Prasad S, Phromnoi K, Ravindran J, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB.

Cancer Prev Res (Phila). 2010 Nov;3(11):1462-72. doi: 10.1158/1940-6207.CAPR-10-0037. Epub 2010 Oct 26.


A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.

Phromnoi K, Reuter S, Sung B, Prasad S, Kannappan R, Yadav VR, Chanmahasathien W, Limtrakul P, Aggarwal BB.

Mol Pharmacol. 2011 Feb;79(2):279-89. doi: 10.1124/mol.110.067512. Epub 2010 Oct 7. Retraction in: Mol Pharmacol. 2016 Jul;90(1):64.


Embelin suppresses osteoclastogenesis induced by receptor activator of NF-κB ligand and tumor cells in vitro through inhibition of the NF-κB cell signaling pathway.

Reuter S, Prasad S, Phromnoi K, Kannappan R, Yadav VR, Aggarwal BB.

Mol Cancer Res. 2010 Oct;8(10):1425-36. doi: 10.1158/1541-7786.MCR-10-0141. Epub 2010 Sep 8. Retraction in: Mol Cancer Res. 2018 Sep;16(9):1443.


Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer.

Prasad S, Phromnoi K, Yadav VR, Chaturvedi MM, Aggarwal BB.

Planta Med. 2010 Aug;76(11):1044-63. doi: 10.1055/s-0030-1250111. Epub 2010 Jul 15. Review.


Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids.

Phromnoi K, Yodkeeree S, Anuchapreeda S, Limtrakul P.

Acta Pharmacol Sin. 2009 Aug;30(8):1169-76. doi: 10.1038/aps.2009.107. Epub 2009 Jul 20.

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