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Items: 25

1.

Characterisation of amyloid-induced inflammatory responses in the rat retina.

Howlett DR, Bate ST, Collier S, Lawman A, Chapman T, Ashmeade T, Marshall I, Anderson PJ, Philpott KL, Richardson JC, Hille CJ.

Exp Brain Res. 2011 Oct;214(2):185-97. doi: 10.1007/s00221-011-2819-4. Epub 2011 Aug 18.

PMID:
21850448
2.

Discovery of a brain-penetrant S1P₃-sparing direct agonist of the S1P₁ and S1P₅ receptors efficacious at low oral dose.

Demont EH, Arpino S, Bit RA, Campbell CA, Deeks N, Desai S, Dowell SJ, Gaskin P, Gray JR, Harrison LA, Haynes A, Heightman TD, Holmes DS, Humphreys PG, Kumar U, Morse MA, Osborne GJ, Panchal T, Philpott KL, Taylor S, Watson R, Willis R, Witherington J.

J Med Chem. 2011 Oct 13;54(19):6724-33. doi: 10.1021/jm200609t. Epub 2011 Sep 9.

PMID:
21838322
3.

Dynamic association of tau with neuronal membranes is regulated by phosphorylation.

Pooler AM, Usardi A, Evans CJ, Philpott KL, Noble W, Hanger DP.

Neurobiol Aging. 2012 Feb;33(2):431.e27-38. doi: 10.1016/j.neurobiolaging.2011.01.005. Epub 2011 Mar 8.

PMID:
21388709
4.

Principles of early drug discovery.

Hughes JP, Rees S, Kalindjian SB, Philpott KL.

Br J Pharmacol. 2011 Mar;162(6):1239-49. doi: 10.1111/j.1476-5381.2010.01127.x. Review.

5.

Differential effects of amyloid-β peptide aggregation status on in vivo retinal neurotoxicity.

Watts HR, Anderson P, Ma D, Philpott KL, Jen SM, Croucher M, Jen LS, Gentleman SM.

Eye Brain. 2010 Sep 9;2:121-137. eCollection 2010.

6.

Glial and endothelial blood-retinal barrier responses to amyloid-beta in the neural retina of the rat.

Anderson PJ, Watts H, Hille C, Philpott K, Clark P, Gentleman MC, Jen LS.

Clin Ophthalmol. 2008 Dec;2(4):801-16.

7.

FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses.

Papadopoulos D, Rundle J, Patel R, Marshall I, Stretton J, Eaton R, Richardson JC, Gonzalez MI, Philpott KL, Reynolds R.

J Neurosci Res. 2010 Feb 1;88(2):346-59. doi: 10.1002/jnr.22196.

PMID:
19658199
8.

An alternatively spliced form of glycogen synthase kinase-3beta is targeted to growing neurites and growth cones.

Wood-Kaczmar A, Kraus M, Ishiguro K, Philpott KL, Gordon-Weeks PR.

Mol Cell Neurosci. 2009 Nov;42(3):184-94. doi: 10.1016/j.mcn.2009.07.002. Epub 2009 Jul 14.

PMID:
19607922
9.

MAP kinase pathways in neuronal cell death.

Philpott KL, Facci L.

CNS Neurol Disord Drug Targets. 2008 Feb;7(1):83-97. Review.

PMID:
18289035
10.

Expression and purification of functional JNK2beta2: perspectives on high-level production of recombinant MAP kinases.

Savopoulos JW, Dowd S, Armour C, Carter PS, Greenwood CJ, Mills D, Powell D, Pettman GR, Jenkins O, Walsh FS, Philpott KL.

Protein Expr Purif. 2002 Feb;24(1):25-32.

PMID:
11812219
11.

AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.

Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC.

J Biol Chem. 2001 Aug 3;276(31):28969-75. Epub 2001 May 31.

12.

Determination of changes in mRNA expression in a rat model of neuropathic pain by Taqman quantitative RT-PCR.

Macdonald R, Bingham S, Bond BC, Parsons AA, Philpott KL.

Brain Res Mol Brain Res. 2001 May 20;90(1):48-56.

PMID:
11376855
13.

Caspase mRNA expression in a rat model of focal cerebral ischemia.

Harrison DC, Davis RP, Bond BC, Campbell CA, James MF, Parsons AA, Philpott KL.

Brain Res Mol Brain Res. 2001 Apr 18;89(1-2):133-46.

PMID:
11311984
14.

Upregulation of death pathway molecules in rat cerebellar granule neurons undergoing apoptosis.

Ginham R, Harrison DC, Facci L, Skaper S, Philpott KL.

Neurosci Lett. 2001 Apr 20;302(2-3):113-6.

PMID:
11290400
15.

The use of quantitative RT-PCR to measure mRNA expression in a rat model of focal ischemia--caspase-3 as a case study.

Harrison DC, Medhurst AD, Bond BC, Campbell CA, Davis RP, Philpott KL.

Brain Res Mol Brain Res. 2000 Jan 10;75(1):143-9.

PMID:
10648898
16.

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

Neame SJ, Rubin LL, Philpott KL.

J Cell Biol. 1998 Sep 21;142(6):1583-93.

17.

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons.

Philpott KL, McCarthy MJ, Klippel A, Rubin LL.

J Cell Biol. 1997 Nov 3;139(3):809-15.

18.

Involvement of caspases in sympathetic neuron apoptosis.

McCarthy MJ, Rubin LL, Philpott KL.

J Cell Sci. 1997 Sep;110 ( Pt 18):2165-73.

19.

Increased surface phosphatidylserine is an early marker of neuronal apoptosis.

Rimon G, Bazenet CE, Philpott KL, Rubin LL.

J Neurosci Res. 1997 Jun 15;48(6):563-70.

PMID:
9210526
20.

Morphological and biochemical changes in neurons: apoptosis versus mitosis.

Philpott KL, McCarthy MJ, Becker D, Gatchalian C, Rubin LL.

Eur J Neurosci. 1996 Sep;8(9):1906-15.

PMID:
8921281
21.

Apoptosis: the cell cycle and cell death.

Rubin LL, Philpott KL, Brooks SF.

Curr Biol. 1993 Jun 1;3(6):391-4. No abstract available.

PMID:
15335741
22.

Expression of major histocompatibility complex class I antigens at low levels in the thymus induces T cell tolerance via a non-deletional mechanism.

Husbands SD, Schönrich G, Arnold B, Chandler PR, Simpson E, Philpott KL, Tomlinson P, O'Reilly L, Cooke A, Mellor AL.

Eur J Immunol. 1992 Oct;22(10):2655-61.

PMID:
1396970
23.

Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells.

Philpott KL, Viney JL, Kay G, Rastan S, Gardiner EM, Chae S, Hayday AC, Owen MJ.

Science. 1992 Jun 5;256(5062):1448-52.

PMID:
1604321
24.

Expression of H-2 class I genes in murine extra-embryonic tissues.

Philpott KL, Rastan S, Brown S, Mellor AL.

Immunology. 1988 Jul;64(3):479-85.

25.

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