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Items: 1 to 50 of 118

1.

Analysis of Chromatin Binding of Ectopically Expressed Proteins in Early Xenopus Embryos.

Hardwick LJA, Philpott A.

Cold Spring Harb Protoc. 2019 Jul 1;2019(7):pdb.prot105577. doi: 10.1101/pdb.prot105577.

PMID:
31138717
2.

Analysis of Phosphorylation Status of Ectopically Expressed Proteins in Early Xenopus Embryos.

Hardwick LJA, Philpott A.

Cold Spring Harb Protoc. 2019 Jul 1;2019(7):pdb.prot105569. doi: 10.1101/pdb.prot105569.

PMID:
31138716
3.

Multi-site phosphorylation controls the neurogenic and myogenic activity of E47.

Hardwick LJA, Davies JD, Philpott A.

Biochem Biophys Res Commun. 2019 Mar 26;511(1):111-116. doi: 10.1016/j.bbrc.2019.02.045. Epub 2019 Feb 14.

4.

N-terminal phosphorylation of xHes1 controls inhibition of primary neurogenesis in Xenopus.

Hardwick LJA, Philpott A.

Biochem Biophys Res Commun. 2019 Feb 5;509(2):557-563. doi: 10.1016/j.bbrc.2018.12.135. Epub 2018 Dec 29.

5.

Xenopus Models of Cancer: Expanding the Oncologist's Toolbox.

Hardwick LJA, Philpott A.

Front Physiol. 2018 Nov 27;9:1660. doi: 10.3389/fphys.2018.01660. eCollection 2018. Review.

6.

Interaction between opposing modes of phospho-regulation of the proneural proteins Ascl1 and Ngn2.

Hardwick LJA, Philpott A.

Wellcome Open Res. 2018 Oct 1;3:129. doi: 10.12688/wellcomeopenres.14848.1. eCollection 2018.

7.

The N terminus of Ascl1 underlies differing proneural activity of mouse and Xenopus Ascl1 proteins.

Hardwick LJA, Philpott A.

Wellcome Open Res. 2018 Sep 26;3:125. doi: 10.12688/wellcomeopenres.14842.1. eCollection 2018.

8.

Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells.

Azzarelli R, Rulands S, Nestorowa S, Davies J, Campinoti S, Gillotin S, Bonfanti P, Göttgens B, Huch M, Simons B, Philpott A.

Sci Rep. 2018 Oct 18;8(1):15374. doi: 10.1038/s41598-018-33838-5.

9.

Cell cycle-dependent phosphorylation and regulation of cellular differentiation.

Hardwick LJA, Azzarelli R, Philpott A.

Biochem Soc Trans. 2018 Oct 19;46(5):1083-1091. doi: 10.1042/BST20180276. Epub 2018 Sep 20. Review.

PMID:
30242121
10.

Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration.

Tomic G, Morrissey E, Kozar S, Ben-Moshe S, Hoyle A, Azzarelli R, Kemp R, Chilamakuri CSR, Itzkovitz S, Philpott A, Winton DJ.

Cell Stem Cell. 2018 Sep 6;23(3):436-443.e7. doi: 10.1016/j.stem.2018.07.002. Epub 2018 Aug 9.

11.

Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.

Sznurkowska MK, Hannezo E, Azzarelli R, Rulands S, Nestorowa S, Hindley CJ, Nichols J, Göttgens B, Huch M, Philpott A, Simons BD.

Dev Cell. 2018 Aug 6;46(3):360-375.e5. doi: 10.1016/j.devcel.2018.06.028. Epub 2018 Jul 26.

12.

Calculating the Degradation Rate of Individual Proteins Using Xenopus Extract Systems.

McDowell GS, Philpott A.

Cold Spring Harb Protoc. 2019 Jun 3;2019(6):pdb.prot103481. doi: 10.1101/pdb.prot103481.

PMID:
29769400
13.

Assessing Ubiquitylation of Individual Proteins Using Xenopus Extract Systems.

McDowell GS, Philpott A.

Cold Spring Harb Protoc. 2019 Jun 3;2019(6):pdb.prot104513. doi: 10.1101/pdb.prot104513.

PMID:
29769387
14.

Factors influencing reoperation following breast-conserving surgery.

Philpott A, Wong J, Elder K, Gorelik A, Mann GB, Skandarajah A.

ANZ J Surg. 2018 Sep;88(9):922-927. doi: 10.1111/ans.14467. Epub 2018 May 15.

PMID:
29763991
15.

The developmental origin of brain tumours: a cellular and molecular framework.

Azzarelli R, Simons BD, Philpott A.

Development. 2018 May 14;145(10). pii: dev162693. doi: 10.1242/dev.162693. Review.

16.

Universality of clone dynamics during tissue development.

Rulands S, Lescroart F, Chabab S, Hindley CJ, Prior N, Sznurkowska MK, Huch M, Philpott A, Blanpain C, Simons BD.

Nat Phys. 2018 May;14(5):469-474. doi: 10.1038/s41567-018-0055-6. Epub 2018 Feb 26.

17.

Subcellular localisation modulates ubiquitylation and degradation of Ascl1.

Gillotin S, Davies JD, Philpott A.

Sci Rep. 2018 Mar 15;8(1):4625. doi: 10.1038/s41598-018-23056-4.

18.

Modified Dorsal Approach in the Management of Lisfranc Injuries.

Philpott A, Lawford C, Lau SC, Chambers S, Bozin M, Oppy A.

Foot Ankle Int. 2018 May;39(5):573-584. doi: 10.1177/1071100717750837. Epub 2018 Jan 10.

PMID:
29320935
19.

Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.

Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Göttgens B, Huch M, Evan G, Simons BD, Winton D, Philpott A.

Dev Cell. 2017 May 8;41(3):274-286.e5. doi: 10.1016/j.devcel.2017.04.004. Epub 2017 Apr 27.

20.

MyoD phosphorylation on multiple C terminal sites regulates myogenic conversion activity.

Hardwick LJ, Davies JD, Philpott A.

Biochem Biophys Res Commun. 2016 Dec 2;481(1-2):97-103. doi: 10.1016/j.bbrc.2016.11.009. Epub 2016 Nov 4.

21.

Ubiquitin-mediated proteolysis in Xenopus extract.

McDowell GS, Philpott A.

Int J Dev Biol. 2016;60(7-8-9):263-270. Review.

22.

Cortical inhibitory deficits in Huntington's disease are not influenced by gender.

Philpott AL, Cummins TD, Bailey NW, Churchyard A, Fitzgerald PB, Georgiou-Karistianis N.

Psychiatry Res Neuroimaging. 2016 Nov 30;257:1-4. doi: 10.1016/j.pscychresns.2016.04.018. Epub 2016 Sep 22.

PMID:
27685894
23.

Characterizing social communication changes in amyotrophic lateral sclerosis.

Fisher F, Philpott A, Andrews SC, Maule R, Douglas J.

Int J Lang Commun Disord. 2017 Mar;52(2):137-142. doi: 10.1111/1460-6984.12267. Epub 2016 Jun 30.

PMID:
27363686
24.

New Insights Into the Role of Ubiquitylation of Proteins.

McDowell GS, Philpott A.

Int Rev Cell Mol Biol. 2016;325:35-88. doi: 10.1016/bs.ircmb.2016.02.002. Epub 2016 Mar 8. Review.

PMID:
27241218
25.

Emotion Evaluation and Social Inference Impairments in Huntington's Disease.

Philpott AL, Andrews SC, Staios M, Churchyard A, Fisher F.

J Huntingtons Dis. 2016 May 3;5(2):175-83. doi: 10.3233/JHD-160190.

PMID:
27163947
26.

A GABBR2 gene variant modifies pathophysiology in Huntington's disease.

Philpott AL, Fitzgerald PB, Bailey NW, Churchyard A, Georgiou-Karistianis N, Cummins TD.

Neurosci Lett. 2016 May 4;620:8-13. doi: 10.1016/j.neulet.2016.03.038. Epub 2016 Mar 23.

PMID:
27033668
27.

Cortical inhibitory deficits in premanifest and early Huntington's disease.

Philpott AL, Cummins TDR, Bailey NW, Churchyard A, Fitzgerald PB, Georgiou-Karistianis N.

Behav Brain Res. 2016 Jan 1;296:311-317. doi: 10.1016/j.bbr.2015.09.030. Epub 2015 Sep 28.

PMID:
26416671
28.
29.

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma.

Wylie LA, Hardwick LJ, Papkovskaia TD, Thiele CJ, Philpott A.

Dis Model Mech. 2015 May;8(5):429-41. doi: 10.1242/dmm.018630. Epub 2015 Mar 18.

30.

An oncologist׳s friend: How Xenopus contributes to cancer research.

Hardwick LJ, Philpott A.

Dev Biol. 2015 Dec 15;408(2):180-7. doi: 10.1016/j.ydbio.2015.02.003. Epub 2015 Feb 19. Review.

31.

Emergence of neuronal diversity from patterning of telencephalic progenitors.

Azzarelli R, Hardwick LJ, Philpott A.

Wiley Interdiscip Rev Dev Biol. 2015 May-Jun;4(3):197-214. doi: 10.1002/wdev.174. Epub 2015 Jan 23. Review.

PMID:
25619507
32.

Multi-site phospho-regulation of proneural transcription factors controls proliferation versus differentiation in development and reprogramming.

Philpott A.

Neurogenesis (Austin). 2015 Aug 7;2(1):e1049733. doi: 10.1080/23262133.2015.1049733. eCollection 2015.

33.

Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2.

McDowell GS, Hindley CJ, Lippens G, Landrieu I, Philpott A.

BMC Biochem. 2014 Nov 6;15:24. doi: 10.1186/s12858-014-0024-3.

34.

Lineage selection and plasticity in the intestinal crypt.

Philpott A, Winton DJ.

Curr Opin Cell Biol. 2014 Dec;31:39-45. doi: 10.1016/j.ceb.2014.07.002. Epub 2014 Sep 15. Review.

35.

Complex domain interactions regulate stability and activity of closely related proneural transcription factors.

McDowell GS, Hardwick LJ, Philpott A.

Biochem Biophys Res Commun. 2014 Aug 8;450(4):1283-90. doi: 10.1016/j.bbrc.2014.06.127. Epub 2014 Jul 3.

36.

Cell cycle regulation of proliferation versus differentiation in the central nervous system.

Hardwick LJ, Ali FR, Azzarelli R, Philpott A.

Cell Tissue Res. 2015 Jan;359(1):187-200. doi: 10.1007/s00441-014-1895-8. Epub 2014 May 25. Review.

37.

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.

Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A.

Development. 2014 Jun;141(11):2216-24. doi: 10.1242/dev.106377. Epub 2014 May 12.

38.

Nervous decision-making: to divide or differentiate.

Hardwick LJ, Philpott A.

Trends Genet. 2014 Jun;30(6):254-61. doi: 10.1016/j.tig.2014.04.001. Epub 2014 Apr 30. Review.

39.

Predictive outcomes of revision total hip replacement--a consecutive series of 1176 patients with a minimum 10-year follow-up.

Philpott A, Weston-Simons JS, Grammatopoulos G, Bejon P, Gill HS, McLardy-Smith P, Gundle R, Murray DW, Pandit H.

Maturitas. 2014 Feb;77(2):185-90. doi: 10.1016/j.maturitas.2013.10.019. Epub 2013 Nov 7.

PMID:
24289896
40.

Time dependency of outcomes for drug-eluting vs bare-metal stents.

Leung AA, Southern DA, Galbraith PD, Knudtson ML, Philpott AC, Ghali WA; APPROACH Investigators.

Can J Cardiol. 2013 Dec;29(12):1616-22. doi: 10.1016/j.cjca.2013.09.003.

PMID:
24267804
41.

The effect of particle agglomeration on the formation of a surface-connected compartment induced by hydroxyapatite nanoparticles in human monocyte-derived macrophages.

Müller KH, Motskin M, Philpott AJ, Routh AF, Shanahan CM, Duer MJ, Skepper JN.

Biomaterials. 2014 Jan;35(3):1074-88. doi: 10.1016/j.biomaterials.2013.10.041. Epub 2013 Oct 30.

42.

Non-canonical ubiquitylation: mechanisms and consequences.

McDowell GS, Philpott A.

Int J Biochem Cell Biol. 2013 Aug;45(8):1833-42. doi: 10.1016/j.biocel.2013.05.026. Epub 2013 May 31. Review.

43.

Transcranial magnetic stimulation as a tool for understanding neurophysiology in Huntington's disease: a review.

Philpott AL, Fitzgerald PB, Cummins TD, Georgiou-Karistianis N.

Neurosci Biobehav Rev. 2013 Sep;37(8):1420-33. doi: 10.1016/j.neubiorev.2013.05.009. Epub 2013 May 29. Review.

PMID:
23727400
44.

The cell cycle and pluripotency.

Hindley C, Philpott A.

Biochem J. 2013 Apr 15;451(2):135-43. doi: 10.1042/BJ20121627. Review.

45.

Complex regulation controls Neurogenin3 proteolysis.

Roark R, Itzhaki L, Philpott A.

Biol Open. 2012 Dec 15;1(12):1264-72. doi: 10.1242/bio.20121750. Epub 2012 Oct 16.

46.

Niacin improves lipid profile but not endothelial function in patients with coronary artery disease on high dose statin therapy.

Philpott AC, Hubacek J, Sun YC, Hillard D, Anderson TJ.

Atherosclerosis. 2013 Feb;226(2):453-8. doi: 10.1016/j.atherosclerosis.2012.10.067. Epub 2012 Nov 5.

PMID:
23174368
47.

Flexion following hip resurfacing and factors that influence it.

Grammatopoulos G, Philpott A, Reilly K, Pandit H, Barker K, Murray DW, Gill HS.

Hip Int. 2012 May-Jun;22(3):266-73. doi: 10.5301/HIP.2012.9280.

PMID:
22740280
48.

Co-ordination of cell cycle and differentiation in the developing nervous system.

Hindley C, Philpott A.

Biochem J. 2012 Jun 15;444(3):375-82. doi: 10.1042/BJ20112040. Review.

49.

Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.

Hindley C, Ali F, McDowell G, Cheng K, Jones A, Guillemot F, Philpott A.

Development. 2012 May;139(10):1718-23. doi: 10.1242/dev.077552. Epub 2012 Apr 4.

50.

Hes6 is required for the neurogenic activity of neurogenin and NeuroD.

Murai K, Philpott A, Jones PH.

PLoS One. 2011;6(11):e27880. doi: 10.1371/journal.pone.0027880. Epub 2011 Nov 16.

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